PABPC3 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	PABPC3
Entrez Gene ID	5042
Full Name	poly(A) binding protein cytoplasmic 3
Synonyms	PABP3,PABPL3,tPABP
General protein information	Preferred Names poly(A) binding protein cytoplasmic 3 Names polyadenylate-binding protein 3 PABP-3 poly(A)-binding protein 3 poly(A)-binding protein-like 3 testis PABP testis-specific poly(A)-binding protein (PABP) testis-specific poly(A)-binding protein 3
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 13 Map Location: 13q12.13
Summary	Messenger RNA stability and translation initiation are extensively under the control of poly(A)-binding proteins (PABP). See PABPC1 (MIM 604679) for background information.[supplied by OMIM, Jul 2002].
Disorder MIM:	604680

mRNA and Protein(s)

mRNA	Protein	Name
NM_030979.2	NP_112241.2	polyadenylate-binding protein 3

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	PABPC3	XP_001154541.1
	PABPC1	XP_001096930.2
Homo sapiens (human)	PABPC3	NP_112241.2
Danio rerio (zebrafish)	pabpc1a	NP_001026846.1

Gene Ontology
Bibliography

Related articles in PubMed

The poly(A)-binding protein genes, EPAB, PABPC1, and PABPC3 are differentially expressed in infertile men with non-obstructive azoospermia.
Ozturk S, Sozen B, Uysal F, Bassorgun IC, Usta MF, Akkoyunlu G, Demir N
Journal of assisted reproduction and genetics33(3)335-348(2016 Mar)

Emergence of young human genes after a burst of retroposition in primates.
Marques AC, Dupanloup I, Vinckenbosch N, Reymond A, Kaessmann H
PLoS biology3(11)e357(2005 Nov)

Human testis expresses a specific poly(A)-binding protein.
F?ral C, Guella?n G, Pawlak A
Nucleic acids research29(9)1872-83(2001 May)

Chromosomal localization of three human poly(A)-binding protein genes and four related pseudogenes.
F?ral C, Matt?i MG, Pawlak A, Guella?n G
Human genetics105(4)347-53(1999 Oct)

The eukaryotic polypeptide chain releasing factor (eRF3/GSPT) carrying the translation termination signal to the 3'-Poly(A) tail of mRNA. Direct association of erf3/GSPT with polyadenylate-binding protein.
Hoshino S, Imai M, Kobayashi T, Uchida N, Katada T
The Journal of biological chemistry274(24)16677-80(1999 Jun)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

PABPC3 decreased expression in in infertile men with non-obstructive azoospermia
Title: The poly(A)-binding protein genes, EPAB, PABPC1, and PABPC3 are differentially expressed in infertile men with non-obstructive azoospermia.

molecular cloning and expression in testis
Title: Human testis expresses a specific poly(A)-binding protein.

The following PABPC3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the PABPC3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OHu30103	NM_030979.2 Latest version!	Homo sapiens poly(A) binding protein cytoplasmic 3 (PABPC3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

PABPC3 ( NM_030979.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_112241.2 Homo sapiens poly(A) binding protein cytoplasmic 3 (PABPC3), mRNA.

Price & Availability↑

CloneID	OHu30103
Clone ID Related Accession (Same CDS sequence)	NM_030979.2
Accession Version	NM_030979.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1896bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-21
Organism	Homo sapiens(human)
Product	polyadenylate-binding protein 3
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BG718483.1, AF132026.1, BC027617.2 and AA954581.1. On Mar 8, 2004 this sequence version replaced NM_030979.1. ##RefSeq-Attributes-START## RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END##

ATGAACCCCA GCACCCCCAG CTACCCAACG GCCTCGCTCT ACGTGGGGGA CCTCCACCCC 
GACGTGACTG AGGCGATGCT CTACGAGAAG TTCAGCCCGG CAGGGCCCAT CCTCTCCATC 
CGGATCTGCA GGGACTTGAT CACCAGCGGC TCCTCCAACT ACGCGTATGT GAACTTCCAG 
CATACGAAGG ACGCGGAGCA TGCTCTGGAC ACCATGAATT TTGATGTTAT AAAGGGCAAG 
CCAGTACGCA TCATGTGGTC TCAGCGTGAT CCATCACTTC GAAAAAGTGG AGTGGGCAAC 
ATATTCGTTA AAAATCTGGA TAAGTCCATT AATAATAAAG CACTGTATGA TACAGTTTCT 
GCTTTTGGTA ACATCCTTTC GTGTAACGTG GTTTGTGATG AAAATGGTTC CAAGGGTTAT 
GGATTTGTAC ACTTTGAGAC ACACGAAGCA GCTGAAAGAG CTATTAAAAA AATGAACGGA 
ATGCTCCTAA ATGGTCGCAA AGTATTTGTT GGACAATTTA AGTCTCGTAA AGAACGAGAA 
GCTGAACTTG GAGCTAGGGC AAAAGAGTTC CCCAATGTTT ACATCAAGAA TTTTGGAGAA 
GACATGGATG ATGAGCGCCT TAAGGATCTC TTTGGCAAGT TCGGGCCCGC CTTAAGTGTG 
AAAGTAATGA CCGATGAAAG TGGAAAATCC AAAGGATTTG GATTTGTAAG CTTTGAAAGG 
CATGAAGATG CACAGAAAGC TGTAGATGAG ATGAATGGAA AGGAGCTCAA TGGAAAACAA 
ATTTACGTTG GTCGAGCTCA GAAAAAAGTG GAACGGCAGA CGGAACTTAA GCGCACATTT 
GAACAGATGA AGCAAGATAG GATCACCAGA TACCAGGTTG TTAATCTTTA TGTGAAAAAT 
CTTGATGATG GTATTGATGA TGAACGTCTC CGGAAAGCGT TTTCTCCATT TGGTACAATC 
ACTAGTGCAA AGGTTATGAT GGAAGGTGGT CGCAGCAAAG GGTTTGGTTT TGTATGTTTC 
TCCTCCCCAG AAGAAGCCAC TAAAGCAGTT ACAGAAATGA ACGGTAGAAT TGTGGCCACA 
AAGCCATTGT ATGTAGCTTT AGCTCAGCGC AAAGAAGAGC GCCAGGCTTA CCTCACTAAC 
GAGTATATGC AGAGAATGGC AAGTGTACGA GCTGTGCCCA ACCAGCGAGC ACCTCCTTCA 
GGTTACTTCA TGACAGCTGT CCCACAGACT CAGAACCATG CTGCATACTA TCCTCCTAGC 
CAAATTGCTC GACTAAGACC AAGTCCTCGC TGGACTGCTC AGGGTGCCAG ACCTCATCCA 
TTCCAAAATA AGCCCAGTGC TATCCGCCCA GGTGCTCCTA GAGTACCATT TAGTACTATG 
AGACCAGCTT CTTCACAGGT TCCACGAGTC ATGTCAACGC AGCGTGTTGC TAACACATCA 
ACACAGACAG TGGGTCCACG TCCTGCAGCT GCTGCTGCTG CTGCAGCTAC CCCTGCTGTG 
CGCACGGTTC CACGGTATAA ATATGCTGCG GGAGTTCGCA ATCCTCAGCA ACATCGTAAT 
GCACAGCCAC AAGTTACAAT GCAACAGCTT GCTGTTCATG TACAAGGTCA GGAAACTTTG 
ACTGCCTCCA GGTTGGCATC TGCCCCTCCT CAAAAGCAAA AGCAAATGTT AGGTGAACGG 
CTCTTTCCTC TTATTCAAGC CATGCACCCT ACTCTTGCTG GGAAAATCAC TGGCATGTTG 
TTGGAGATTG ATAATTCAGA ACTTCTTTAT ATGCTCGAGT CTCCAGAGTC ACTCCGTTCT 
AAGGTTGATG AAGCTGTAGC TGTACTACAA GCCCACCAAG CTAAAGAGGC TACCCAGAAA 
GCAGTTAACA GTGCTACCGG TGTTCCAACT GTTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_112241.2
CDS	62..1957
Translation	MNPSTPSYPTASLYVGDLHPDVTEAMLYEKFSPAGPILSIRICRDLITSGSSNYAYVNFQHTKDAEHALDTMNFDVIKGKPVRIMWSQRDPSLRKSGVGNIFVKNLDKSINNKALYDTVSAFGNILSCNVVCDENGSKGYGFVHFETHEAAERAIKKMNGMLLNGRKVFVGQFKSRKEREAELGARAKEFPNVYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDESGKSKGFGFVSFERHEDAQKAVDEMNGKELNGKQIYVGRAQKKVERQTELKRTFEQMKQDRITRYQVVNLYVKNLDDGIDDERLRKAFSPFGTITSAKVMMEGGRSKGFGFVCFSSPEEATKAVTEMNGRIVATKPLYVALAQRKEERQAYLTNEYMQRMASVRAVPNQRAPPSGYFMTAVPQTQNHAAYYPPSQIARLRPSPRWTAQGARPHPFQNKPSAIRPGAPRVPFSTMRPASSQVPRVMSTQRVANTSTQTVGPRPAAAAAAAATPAVRTVPRYKYAAGVRNPQQHRNAQPQVTMQQLAVHVQGQETLTASRLASAPPQKQKQMLGERLFPLIQAMHPTLAGKITGMLLEIDNSELLYMLESPESLRSKVDEAVAVLQAHQAKEATQKAVNSATGVPTV

Target ORF information:

RefSeq Version	NM_030979.2
Organism	Homo sapiens(human)
Definition	Homo sapiens poly(A) binding protein cytoplasmic 3 (PABPC3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_030979.2

ORF Insert Sequence:

ATGAACCCCA GCACCCCCAG CTACCCAACG GCCTCGCTCT ACGTGGGGGA CCTCCACCCC 
GACGTGACTG AGGCGATGCT CTACGAGAAG TTCAGCCCGG CAGGGCCCAT CCTCTCCATC 
CGGATCTGCA GGGACTTGAT CACCAGCGGC TCCTCCAACT ACGCGTATGT GAACTTCCAG 
CATACGAAGG ACGCGGAGCA TGCTCTGGAC ACCATGAATT TTGATGTTAT AAAGGGCAAG 
CCAGTACGCA TCATGTGGTC TCAGCGTGAT CCATCACTTC GAAAAAGTGG AGTGGGCAAC 
ATATTCGTTA AAAATCTGGA TAAGTCCATT AATAATAAAG CACTGTATGA TACAGTTTCT 
GCTTTTGGTA ACATCCTTTC GTGTAACGTG GTTTGTGATG AAAATGGTTC CAAGGGTTAT 
GGATTTGTAC ACTTTGAGAC ACACGAAGCA GCTGAAAGAG CTATTAAAAA AATGAACGGA 
ATGCTCCTAA ATGGTCGCAA AGTATTTGTT GGACAATTTA AGTCTCGTAA AGAACGAGAA 
GCTGAACTTG GAGCTAGGGC AAAAGAGTTC CCCAATGTTT ACATCAAGAA TTTTGGAGAA 
GACATGGATG ATGAGCGCCT TAAGGATCTC TTTGGCAAGT TCGGGCCCGC CTTAAGTGTG 
AAAGTAATGA CCGATGAAAG TGGAAAATCC AAAGGATTTG GATTTGTAAG CTTTGAAAGG 
CATGAAGATG CACAGAAAGC TGTAGATGAG ATGAATGGAA AGGAGCTCAA TGGAAAACAA 
ATTTACGTTG GTCGAGCTCA GAAAAAAGTG GAACGGCAGA CGGAACTTAA GCGCACATTT 
GAACAGATGA AGCAAGATAG GATCACCAGA TACCAGGTTG TTAATCTTTA TGTGAAAAAT 
CTTGATGATG GTATTGATGA TGAACGTCTC CGGAAAGCGT TTTCTCCATT TGGTACAATC 
ACTAGTGCAA AGGTTATGAT GGAAGGTGGT CGCAGCAAAG GGTTTGGTTT TGTATGTTTC 
TCCTCCCCAG AAGAAGCCAC TAAAGCAGTT ACAGAAATGA ACGGTAGAAT TGTGGCCACA 
AAGCCATTGT ATGTAGCTTT AGCTCAGCGC AAAGAAGAGC GCCAGGCTTA CCTCACTAAC 
GAGTATATGC AGAGAATGGC AAGTGTACGA GCTGTGCCCA ACCAGCGAGC ACCTCCTTCA 
GGTTACTTCA TGACAGCTGT CCCACAGACT CAGAACCATG CTGCATACTA TCCTCCTAGC 
CAAATTGCTC GACTAAGACC AAGTCCTCGC TGGACTGCTC AGGGTGCCAG ACCTCATCCA 
TTCCAAAATA AGCCCAGTGC TATCCGCCCA GGTGCTCCTA GAGTACCATT TAGTACTATG 
AGACCAGCTT CTTCACAGGT TCCACGAGTC ATGTCAACGC AGCGTGTTGC TAACACATCA 
ACACAGACAG TGGGTCCACG TCCTGCAGCT GCTGCTGCTG CTGCAGCTAC CCCTGCTGTG 
CGCACGGTTC CACGGTATAA ATATGCTGCG GGAGTTCGCA ATCCTCAGCA ACATCGTAAT 
GCACAGCCAC AAGTTACAAT GCAACAGCTT GCTGTTCATG TACAAGGTCA GGAAACTTTG 
ACTGCCTCCA GGTTGGCATC TGCCCCTCCT CAAAAGCAAA AGCAAATGTT AGGTGAACGG 
CTCTTTCCTC TTATTCAAGC CATGCACCCT ACTCTTGCTG GGAAAATCAC TGGCATGTTG 
TTGGAGATTG ATAATTCAGA ACTTCTTTAT ATGCTCGAGT CTCCAGAGTC ACTCCGTTCT 
AAGGTTGATG AAGCTGTAGC TGTACTACAA GCCCACCAAG CTAAAGAGGC TACCCAGAAA 
GCAGTTAACA GTGCTACCGG TGTTCCAACT GTTTAA