MLLT1 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	MLLT1
Entrez Gene ID	4298
Full Name	MLLT1, super elongation complex subunit
Synonyms	ENL,LTG19,YEATS1
General protein information	Preferred Names MLLT1, super elongation complex subunit Names protein ENL CTC-503J8.6 ENL/MLL fusion MLL/ENL fusion protein MLLT1/MLL fusion YEATS domain-containing protein 1 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog); translocated to, 1 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1 myeloid/lymphoid or mixed-lineage leukemia; translocated to, 1
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 19 Map Location: 19p13.3
Disorder MIM:	159556

mRNA and Protein(s)

mRNA	Protein	Name
NM_005934.3	NP_005925.2	protein ENL
XM_011528021.1	XP_011526323.1	protein ENL isoform X1
XM_017026819.2	XP_016882308.1	protein ENL isoform X4
NM_005934.4	NP_005925.2	protein ENL
XM_017026819.1	XP_016882308.1	protein ENL isoform X4
XM_011528022.1	XP_011526324.1	protein ENL isoform X2
XM_011528023.1	XP_011526325.1	protein ENL isoform X3

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Mllt1	NP_071723.1
Danio rerio (zebrafish)	mllt1	XP_693860.6
Xenopus tropicalis (tropical clawed frog)	mllt1	NP_001121476.1
Danio rerio (zebrafish)	zgc:136639	NP_001035474.1
	MLLT1	XP_001090388.2
Rattus norvegicus (Norway rat)	Mllt1	NP_001100346.1
Homo sapiens (human)	MLLT1	NP_005925.2
Pan troglodytes (chimpanzee)	MLLT1	XP_001143317.2
Canis lupus familiaris (dog)	MLLT1	XP_542141.4
Bos taurus (cattle)	MLLT1	XP_002688960.2
Gallus gallus (chicken)	MLLT1	XP_418209.4

Gene Ontology
Bibliography

Related articles in PubMed

ENL links histone acetylation to oncogenic gene expression in acute myeloid leukaemia.
Wan L, Wen H, Li Y, Lyu J, Xi Y, Hoshii T, Joseph JK, Wang X, Loh YE, Erb MA, Souza AL, Bradner JE, Shen L, Li W, Li H, Allis CD, Armstrong SA, Shi X
Nature543(7644)265-269(2017 03)

MLLT1 YEATS domain mutations in clinically distinctive Favourable Histology Wilms tumours.
Perlman EJ, Gadd S, Arold ST, Radhakrishnan A, Gerhard DS, Jennings L, Huff V, Guidry Auvil JM, Davidsen TM, Dome JS, Meerzaman D, Hsu CH, Nguyen C, Anderson J, Ma Y, Mungall AJ, Moore RA, Marra MA, Mullighan CG, Ma J, Wheeler DA, Hampton OA, Gastier-Foster JM, Ross N, Smith MA
Nature communications610013(2015 Dec)

Transcriptional elongation factor ENL phosphorylated by ATM recruits polycomb and switches off transcription for DSB repair.
Ui A, Nagaura Y, Yasui A
Molecular cell58(3)468-82(2015 May)

An AF9/ENL-targted peptide with therapeutic potential in mixed lineage leukemias.
Barretto NN, Karahalios DS, You D, Hemenway CS
Journal of experimental therapeutics & oncology10(4)293-300(2014)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

data identify ENL as a histone acetylation reader that regulates oncogenic transcriptional programs in acute myeloid leukaemia, and suggest that displacement of ENL from chromatin may be a promising epigenetic therapy, alone or in combination with BET inhibitors, for aggressive leukaemia
Title: ENL links histone acetylation to oncogenic gene expression in acute myeloid leukaemia.

Recurrent mutations within Wilms tumours involve the highly conserved YEATS domain of MLLT1.
Title: MLLT1 YEATS domain mutations in clinically distinctive Favourable Histology Wilms tumours.

Data suggest that AT mutated protein ATM-dependent phosphorylation of ENL (MLLT1) protein functions as switch from elongation to Polycomb-mediated repression to preserve genome integrity.
Title: Transcriptional elongation factor ENL phosphorylated by ATM recruits polycomb and switches off transcription for DSB repair.

Novel splice isoform of Mllt1 is documented and confirmed that both Mllt1 mRNA isoforms are translated. The data support that MLLT1 protein isoforms display distinct stage-specific expression during spermiogenesis and adult tissues.
Title: Identification of a novel isoform of the leukemia-associated MLLT1 (ENL/LTG19) protein.

AF9 and its homolog ENL directly interact with AF4.
Title: An AF9/ENL-targted peptide with therapeutic potential in mixed lineage leukemias.

The following MLLT1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the MLLT1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu05246	NM_005934.4 Latest version!	Homo sapiens MLLT1 super elongation complex subunit (MLLT1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
OHu59000	XM_011528021.1 Latest version!	Homo sapiens MLLT1 super elongation complex subunit (MLLT1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
OHu59001	XM_011528022.1 Latest version!	Homo sapiens MLLT1 super elongation complex subunit (MLLT1), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
OHu59002	XM_011528023.1 Latest version!	Homo sapiens MLLT1 super elongation complex subunit (MLLT1), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
OHu88473	XM_017026819.2 Latest version!	Homo sapiens MLLT1 super elongation complex subunit (MLLT1), transcript variant X4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	10-12	$307.30 $439.00
View Old Accession Versions >>
OHu05246	NM_005934.3	Homo sapiens MLLT1, super elongation complex subunit (MLLT1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
OHu88473	XM_017026819.1	Homo sapiens myeloid/lymphoid or mixed-lineage leukemia; translocated to, 1 (MLLT1), transcript variant X4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	10-12	$307.30 $439.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

MLLT1 ( NM_005934.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_005925.2 Homo sapiens MLLT1, super elongation complex subunit (MLLT1), mRNA.

Price & Availability↑

CloneID	OHu05246
Clone ID Related Accession (Same CDS sequence)	NM_005934.3 , NM_005934.4
Accession Version	NM_005934.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1680bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Homo sapiens(human)
Product	protein ENL
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from D14539.1, AC011471.6 and BC047008.1. On Mar 24, 2006 this sequence version replaced NM_005934.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: D14539.1, L04285.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END##

ATGGACAATC AGTGCACCGT CCAGGTGAGG TTAGAGCTGG GGCATCGCGC CCAACTGCGC 
AAGAAGCCCA CCACGGAGGG GTTCACTCAC GACTGGATGG TGTTTGTCCG CGGCCCCGAG 
CAATGTGACA TCCAGCACTT CGTGGAGAAG GTGGTCTTCT GGCTGCACGA CAGCTTCCCC 
AAGCCCAGAC GCGTGTGCAA GGAGCCCCCC TACAAAGTAG AGGAGTCGGG GTACGCTGGC 
TTCATCATGC CCATCGAGGT GCACTTCAAA AACAAGGAGG AGCCGAGGAA GGTCTGCTTC 
ACCTACGACC TGTTCCTGAA CCTGGAAGGC AACCCGCCCG TGAACCACCT GCGCTGCGAG 
AAGCTCACCT TCAACAACCC CACCACGGAG TTCCGGTACA AGCTCCTGCG GGCCGGCGGG 
GTGATGGTAA TGCCCGAAGG AGCAGACACG GTGTCCAGGC CCAGTCCCGA CTACCCCATG 
TTACCCACAA TTCCACTCTC TGCCTTCTCT GACCCCAAGA AGACCAAACC ATCCCACGGC 
TCCAAGGACG CCAACAAGGA GAGCAGCAAG ACCTCCAAGC CACACAAGGT GACCAAGGAG 
CACCGGGAGC GGCCCCGCAA AGACTCCGAG AGCAAGAGCT CCTCCAAGGA GCTGGAGCGT 
GAGCAGGCCA AAAGCTCCAA GGACACCTCG CGGAAGCTGG GCGAGGGCCG GCTGCCCAAG 
GAGGAGAAGG CGCCACCGCC CAAGGCTGCC TTCAAGGAAC CCAAGATGGC CCTGAAAGAG 
ACCAAGCTGG AAAGCACGTC CCCCAAGGGT GGGCCCCCAC CCCCACCCCC ACCCCCACCC 
CGGGCTTCCA GCAAGCGGCC GGCCACCGCC GACTCGCCAA AGCCCAGCGC CAAGAAGCAG 
AAGAAGAGCA GCTCGAAGGG GTCCCGGAGT GCTCCAGGCA CCTCGCCCCG CACCTCCTCC 
TCCTCCTCCT TCTCGGACAA GAAGCCGGCC AAGGACAAGA GCAGCACCAG AGGGGAGAAG 
GTGAAGGCCG AGAGTGAGCC CCGGGAGGCC AAAAAGGCCC TGGAGGTGGA GGAGTCCAAC 
TCAGAGGACG AGGCCTCCTT CAAGTCCGAG TCTGCCCAGT CAAGCCCGTC CAACTCCAGC 
TCCAGCTCAG ACTCCAGCTC AGACTCAGAC TTCGAGCCAT CCCAGAACCA CAGCCAAGGA 
CCCCTGCGCT CCATGGTGGA GGACCTGCAG TCCGAGGAGT CCGACGAGGA CGACTCTTCG 
TCAGGCGAGG AGGCTGCCGG CAAGACCAAC CCGGGGAGGG ACTCCAGGTT GAGCTTCAGC 
GACAGCGAGA GTGACAACAG CGCCGACTCC TCCCTGCCCA GCCGTGAGCC CCCACCCCCC 
CAGAAGCCAC CCCCGCCCAA CAGCAAGGTG TCAGGCCGGA GGAGCCCCGA GTCCTGCAGC 
AAGCCTGAGA AGATCCTCAA GAAGGGCACC TACGACAAGG CCTACACGGA TGAGCTGGTG 
GAGCTACACC GGAGGCTGAT GGCGCTGCGG GAGCGCAACG TGCTGCAGCA GATTGTGAAT 
CTGATCGAGG AGACTGGCCA CTTCAATGTC ACCAACACCA CCTTCGACTT CGACCTCTTC 
TCCCTGGACG AGACCACCGT GCGCAAACTG CAGAGCTGCC TGGAGGCCGT GGCCACATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_005925.2
CDS	165..1844
Translation	MDNQCTVQVRLELGHRAQLRKKPTTEGFTHDWMVFVRGPEQCDIQHFVEKVVFWLHDSFPKPRRVCKEPPYKVEESGYAGFIMPIEVHFKNKEEPRKVCFTYDLFLNLEGNPPVNHLRCEKLTFNNPTTEFRYKLLRAGGVMVMPEGADTVSRPSPDYPMLPTIPLSAFSDPKKTKPSHGSKDANKESSKTSKPHKVTKEHRERPRKDSESKSSSKELEREQAKSSKDTSRKLGEGRLPKEEKAPPPKAAFKEPKMALKETKLESTSPKGGPPPPPPPPPRASSKRPATADSPKPSAKKQKKSSSKGSRSAPGTSPRTSSSSSFSDKKPAKDKSSTRGEKVKAESEPREAKKALEVEESNSEDEASFKSESAQSSPSNSSSSSDSSSDSDFEPSQNHSQGPLRSMVEDLQSEESDEDDSSSGEEAAGKTNPGRDSRLSFSDSESDNSADSSLPSREPPPPQKPPPPNSKVSGRRSPESCSKPEKILKKGTYDKAYTDELVELHRRLMALRERNVLQQIVNLIEETGHFNVTNTTFDFDLFSLDETTVRKLQSCLEAVAT

Target ORF information:

RefSeq Version	NM_005934.3
Organism	Homo sapiens(human)
Definition	Homo sapiens MLLT1, super elongation complex subunit (MLLT1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_005934.3

ORF Insert Sequence:

ATGGACAATC AGTGCACCGT CCAGGTGAGG TTAGAGCTGG GGCATCGCGC CCAACTGCGC 
AAGAAGCCCA CCACGGAGGG GTTCACTCAC GACTGGATGG TGTTTGTCCG CGGCCCCGAG 
CAATGTGACA TCCAGCACTT CGTGGAGAAG GTGGTCTTCT GGCTGCACGA CAGCTTCCCC 
AAGCCCAGAC GCGTGTGCAA GGAGCCCCCC TACAAAGTAG AGGAGTCGGG GTACGCTGGC 
TTCATCATGC CCATCGAGGT GCACTTCAAA AACAAGGAGG AGCCGAGGAA GGTCTGCTTC 
ACCTACGACC TGTTCCTGAA CCTGGAAGGC AACCCGCCCG TGAACCACCT GCGCTGCGAG 
AAGCTCACCT TCAACAACCC CACCACGGAG TTCCGGTACA AGCTCCTGCG GGCCGGCGGG 
GTGATGGTAA TGCCCGAAGG AGCAGACACG GTGTCCAGGC CCAGTCCCGA CTACCCCATG 
TTACCCACAA TTCCACTCTC TGCCTTCTCT GACCCCAAGA AGACCAAACC ATCCCACGGC 
TCCAAGGACG CCAACAAGGA GAGCAGCAAG ACCTCCAAGC CACACAAGGT GACCAAGGAG 
CACCGGGAGC GGCCCCGCAA AGACTCCGAG AGCAAGAGCT CCTCCAAGGA GCTGGAGCGT 
GAGCAGGCCA AAAGCTCCAA GGACACCTCG CGGAAGCTGG GCGAGGGCCG GCTGCCCAAG 
GAGGAGAAGG CGCCACCGCC CAAGGCTGCC TTCAAGGAAC CCAAGATGGC CCTGAAAGAG 
ACCAAGCTGG AAAGCACGTC CCCCAAGGGT GGGCCCCCAC CCCCACCCCC ACCCCCACCC 
CGGGCTTCCA GCAAGCGGCC GGCCACCGCC GACTCGCCAA AGCCCAGCGC CAAGAAGCAG 
AAGAAGAGCA GCTCGAAGGG GTCCCGGAGT GCTCCAGGCA CCTCGCCCCG CACCTCCTCC 
TCCTCCTCCT TCTCGGACAA GAAGCCGGCC AAGGACAAGA GCAGCACCAG AGGGGAGAAG 
GTGAAGGCCG AGAGTGAGCC CCGGGAGGCC AAAAAGGCCC TGGAGGTGGA GGAGTCCAAC 
TCAGAGGACG AGGCCTCCTT CAAGTCCGAG TCTGCCCAGT CAAGCCCGTC CAACTCCAGC 
TCCAGCTCAG ACTCCAGCTC AGACTCAGAC TTCGAGCCAT CCCAGAACCA CAGCCAAGGA 
CCCCTGCGCT CCATGGTGGA GGACCTGCAG TCCGAGGAGT CCGACGAGGA CGACTCTTCG 
TCAGGCGAGG AGGCTGCCGG CAAGACCAAC CCGGGGAGGG ACTCCAGGTT GAGCTTCAGC 
GACAGCGAGA GTGACAACAG CGCCGACTCC TCCCTGCCCA GCCGTGAGCC CCCACCCCCC 
CAGAAGCCAC CCCCGCCCAA CAGCAAGGTG TCAGGCCGGA GGAGCCCCGA GTCCTGCAGC 
AAGCCTGAGA AGATCCTCAA GAAGGGCACC TACGACAAGG CCTACACGGA TGAGCTGGTG 
GAGCTACACC GGAGGCTGAT GGCGCTGCGG GAGCGCAACG TGCTGCAGCA GATTGTGAAT 
CTGATCGAGG AGACTGGCCA CTTCAATGTC ACCAACACCA CCTTCGACTT CGACCTCTTC 
TCCCTGGACG AGACCACCGT GCGCAAACTG CAGAGCTGCC TGGAGGCCGT GGCCACATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MLLT1 ( NM_005934.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_005925.2 Homo sapiens MLLT1 super elongation complex subunit (MLLT1), mRNA.

Price & Availability↑

CloneID	OHu05246
Clone ID Related Accession (Same CDS sequence)	NM_005934.3 , NM_005934.4
Accession Version	NM_005934.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1680bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-29
Organism	Homo sapiens(human)
Product	protein ENL
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC011471.6, D14539.1 and BC047008.1. On Nov 23, 2018 this sequence version replaced NM_005934.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: D14539.1, L04285.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000252674.9/ ENSP00000252674.6 RefSeq Select criteria :: based on conservation, expression ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGACAATC AGTGCACCGT CCAGGTGAGG TTAGAGCTGG GGCATCGCGC CCAACTGCGC 
AAGAAGCCCA CCACGGAGGG GTTCACTCAC GACTGGATGG TGTTTGTCCG CGGCCCCGAG 
CAATGTGACA TCCAGCACTT CGTGGAGAAG GTGGTCTTCT GGCTGCACGA CAGCTTCCCC 
AAGCCCAGAC GCGTGTGCAA GGAGCCCCCC TACAAAGTAG AGGAGTCGGG GTACGCTGGC 
TTCATCATGC CCATCGAGGT GCACTTCAAA AACAAGGAGG AGCCGAGGAA GGTCTGCTTC 
ACCTACGACC TGTTCCTGAA CCTGGAAGGC AACCCGCCCG TGAACCACCT GCGCTGCGAG 
AAGCTCACCT TCAACAACCC CACCACGGAG TTCCGGTACA AGCTCCTGCG GGCCGGCGGG 
GTGATGGTAA TGCCCGAAGG AGCAGACACG GTGTCCAGGC CCAGTCCCGA CTACCCCATG 
TTACCCACAA TTCCACTCTC TGCCTTCTCT GACCCCAAGA AGACCAAACC ATCCCACGGC 
TCCAAGGACG CCAACAAGGA GAGCAGCAAG ACCTCCAAGC CACACAAGGT GACCAAGGAG 
CACCGGGAGC GGCCCCGCAA AGACTCCGAG AGCAAGAGCT CCTCCAAGGA GCTGGAGCGT 
GAGCAGGCCA AAAGCTCCAA GGACACCTCG CGGAAGCTGG GCGAGGGCCG GCTGCCCAAG 
GAGGAGAAGG CGCCACCGCC CAAGGCTGCC TTCAAGGAAC CCAAGATGGC CCTGAAAGAG 
ACCAAGCTGG AAAGCACGTC CCCCAAGGGT GGGCCCCCAC CCCCACCCCC ACCCCCACCC 
CGGGCTTCCA GCAAGCGGCC GGCCACCGCC GACTCGCCAA AGCCCAGCGC CAAGAAGCAG 
AAGAAGAGCA GCTCGAAGGG GTCCCGGAGT GCTCCAGGCA CCTCGCCCCG CACCTCCTCC 
TCCTCCTCCT TCTCGGACAA GAAGCCGGCC AAGGACAAGA GCAGCACCAG AGGGGAGAAG 
GTGAAGGCCG AGAGTGAGCC CCGGGAGGCC AAAAAGGCCC TGGAGGTGGA GGAGTCCAAC 
TCAGAGGACG AGGCCTCCTT CAAGTCCGAG TCTGCCCAGT CAAGCCCGTC CAACTCCAGC 
TCCAGCTCAG ACTCCAGCTC AGACTCAGAC TTCGAGCCAT CCCAGAACCA CAGCCAAGGA 
CCCCTGCGCT CCATGGTGGA GGACCTGCAG TCCGAGGAGT CCGACGAGGA CGACTCTTCG 
TCAGGCGAGG AGGCTGCCGG CAAGACCAAC CCGGGGAGGG ACTCCAGGTT GAGCTTCAGC 
GACAGCGAGA GTGACAACAG CGCCGACTCC TCCCTGCCCA GCCGTGAGCC CCCACCCCCC 
CAGAAGCCAC CCCCGCCCAA CAGCAAGGTG TCAGGCCGGA GGAGCCCCGA GTCCTGCAGC 
AAGCCTGAGA AGATCCTCAA GAAGGGCACC TACGACAAGG CCTACACGGA TGAGCTGGTG 
GAGCTACACC GGAGGCTGAT GGCGCTGCGG GAGCGCAACG TGCTGCAGCA GATTGTGAAT 
CTGATCGAGG AGACTGGCCA CTTCAATGTC ACCAACACCA CCTTCGACTT CGACCTCTTC 
TCCCTGGACG AGACCACCGT GCGCAAACTG CAGAGCTGCC TGGAGGCCGT GGCCACATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_005925.2
CDS	192..1871
Translation	MDNQCTVQVRLELGHRAQLRKKPTTEGFTHDWMVFVRGPEQCDIQHFVEKVVFWLHDSFPKPRRVCKEPPYKVEESGYAGFIMPIEVHFKNKEEPRKVCFTYDLFLNLEGNPPVNHLRCEKLTFNNPTTEFRYKLLRAGGVMVMPEGADTVSRPSPDYPMLPTIPLSAFSDPKKTKPSHGSKDANKESSKTSKPHKVTKEHRERPRKDSESKSSSKELEREQAKSSKDTSRKLGEGRLPKEEKAPPPKAAFKEPKMALKETKLESTSPKGGPPPPPPPPPRASSKRPATADSPKPSAKKQKKSSSKGSRSAPGTSPRTSSSSSFSDKKPAKDKSSTRGEKVKAESEPREAKKALEVEESNSEDEASFKSESAQSSPSNSSSSSDSSSDSDFEPSQNHSQGPLRSMVEDLQSEESDEDDSSSGEEAAGKTNPGRDSRLSFSDSESDNSADSSLPSREPPPPQKPPPPNSKVSGRRSPESCSKPEKILKKGTYDKAYTDELVELHRRLMALRERNVLQQIVNLIEETGHFNVTNTTFDFDLFSLDETTVRKLQSCLEAVAT

Target ORF information:

RefSeq Version	NM_005934.4
Organism	Homo sapiens(human)
Definition	Homo sapiens MLLT1 super elongation complex subunit (MLLT1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_005934.4

ORF Insert Sequence:

ATGGACAATC AGTGCACCGT CCAGGTGAGG TTAGAGCTGG GGCATCGCGC CCAACTGCGC 
AAGAAGCCCA CCACGGAGGG GTTCACTCAC GACTGGATGG TGTTTGTCCG CGGCCCCGAG 
CAATGTGACA TCCAGCACTT CGTGGAGAAG GTGGTCTTCT GGCTGCACGA CAGCTTCCCC 
AAGCCCAGAC GCGTGTGCAA GGAGCCCCCC TACAAAGTAG AGGAGTCGGG GTACGCTGGC 
TTCATCATGC CCATCGAGGT GCACTTCAAA AACAAGGAGG AGCCGAGGAA GGTCTGCTTC 
ACCTACGACC TGTTCCTGAA CCTGGAAGGC AACCCGCCCG TGAACCACCT GCGCTGCGAG 
AAGCTCACCT TCAACAACCC CACCACGGAG TTCCGGTACA AGCTCCTGCG GGCCGGCGGG 
GTGATGGTAA TGCCCGAAGG AGCAGACACG GTGTCCAGGC CCAGTCCCGA CTACCCCATG 
TTACCCACAA TTCCACTCTC TGCCTTCTCT GACCCCAAGA AGACCAAACC ATCCCACGGC 
TCCAAGGACG CCAACAAGGA GAGCAGCAAG ACCTCCAAGC CACACAAGGT GACCAAGGAG 
CACCGGGAGC GGCCCCGCAA AGACTCCGAG AGCAAGAGCT CCTCCAAGGA GCTGGAGCGT 
GAGCAGGCCA AAAGCTCCAA GGACACCTCG CGGAAGCTGG GCGAGGGCCG GCTGCCCAAG 
GAGGAGAAGG CGCCACCGCC CAAGGCTGCC TTCAAGGAAC CCAAGATGGC CCTGAAAGAG 
ACCAAGCTGG AAAGCACGTC CCCCAAGGGT GGGCCCCCAC CCCCACCCCC ACCCCCACCC 
CGGGCTTCCA GCAAGCGGCC GGCCACCGCC GACTCGCCAA AGCCCAGCGC CAAGAAGCAG 
AAGAAGAGCA GCTCGAAGGG GTCCCGGAGT GCTCCAGGCA CCTCGCCCCG CACCTCCTCC 
TCCTCCTCCT TCTCGGACAA GAAGCCGGCC AAGGACAAGA GCAGCACCAG AGGGGAGAAG 
GTGAAGGCCG AGAGTGAGCC CCGGGAGGCC AAAAAGGCCC TGGAGGTGGA GGAGTCCAAC 
TCAGAGGACG AGGCCTCCTT CAAGTCCGAG TCTGCCCAGT CAAGCCCGTC CAACTCCAGC 
TCCAGCTCAG ACTCCAGCTC AGACTCAGAC TTCGAGCCAT CCCAGAACCA CAGCCAAGGA 
CCCCTGCGCT CCATGGTGGA GGACCTGCAG TCCGAGGAGT CCGACGAGGA CGACTCTTCG 
TCAGGCGAGG AGGCTGCCGG CAAGACCAAC CCGGGGAGGG ACTCCAGGTT GAGCTTCAGC 
GACAGCGAGA GTGACAACAG CGCCGACTCC TCCCTGCCCA GCCGTGAGCC CCCACCCCCC 
CAGAAGCCAC CCCCGCCCAA CAGCAAGGTG TCAGGCCGGA GGAGCCCCGA GTCCTGCAGC 
AAGCCTGAGA AGATCCTCAA GAAGGGCACC TACGACAAGG CCTACACGGA TGAGCTGGTG 
GAGCTACACC GGAGGCTGAT GGCGCTGCGG GAGCGCAACG TGCTGCAGCA GATTGTGAAT 
CTGATCGAGG AGACTGGCCA CTTCAATGTC ACCAACACCA CCTTCGACTT CGACCTCTTC 
TCCCTGGACG AGACCACCGT GCGCAAACTG CAGAGCTGCC TGGAGGCCGT GGCCACATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MLLT1 ( XM_011528021.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_011526323.1 Homo sapiens MLLT1 super elongation complex subunit (MLLT1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu59000
Clone ID Related Accession (Same CDS sequence)	XM_011528021.1
Accession Version	XM_011528021.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1803bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	protein ENL isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000019.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTGCGCGT TTCCTGCATT TCCTCAGTTC TGGGACTCTG AGATACCAGG ACAGCGCCAC 
CAACTCAGGA GCAGCTTCTG TGTCTGTGTG TGCACGTGTG CGCCTGTGTG CAGGCTGGAC 
TCTGACTTCA AAAGGTGCAC CGTCCAGGTG AGGTTAGAGC TGGGGCATCG CGCCCAACTG 
CGCAAGAAGC CCACCACGGA GGGGTTCACT CACGACTGGA TGGTGTTTGT CCGCGGCCCC 
GAGCAATGTG ACATCCAGCA CTTCGTGGAG AAGGTGGTCT TCTGGCTGCA CGACAGCTTC 
CCCAAGCCCA GACGCGTGTG CAAGGAGCCC CCCTACAAAG TAGAGGAGTC GGGGTACGCT 
GGCTTCATCA TGCCCATCGA GGTGCACTTC AAAAACAAGG AGGAGCCGAG GAAGGTCTGC 
TTCACCTACG ACCTGTTCCT GAACCTGGAA GGCAACCCGC CCGTGAACCA CCTGCGCTGC 
GAGAAGCTCA CCTTCAACAA CCCCACCACG GAGTTCCGGT ACAAGCTCCT GCGGGCCGGC 
GGGGTGATGG TAATGCCCGA AGGAGCAGAC ACGGTGTCCA GGCCCAGTCC CGACTACCCC 
ATGTTACCCA CAATTCCACT CTCTGCCTTC TCTGACCCCA AGAAGACCAA ACCATCCCAC 
GGCTCCAAGG ACGCCAACAA GGAGAGCAGC AAGACCTCCA AGCCACACAA GGTGACCAAG 
GAGCACCGGG AGCGGCCCCG CAAAGACTCC GAGAGCAAGA GCTCCTCCAA GGAGCTGGAG 
CGTGAGCAGG CCAAAAGCTC CAAGGACACC TCGCGGAAGC TGGGCGAGGG CCGGCTGCCC 
AAGGAGGAGA AGGCGCCACC GCCCAAGGCT GCCTTCAAGG AACCCAAGAT GGCCCTGAAA 
GAGACCAAGC TGGAAAGCAC GTCCCCCAAG GGTGGGCCCC CACCCCCACC CCCACCCCCA 
CCCCGGGCTT CCAGCAAGCG GCCGGCCACC GCCGACTCGC CAAAGCCCAG CGCCAAGAAG 
CAGAAGAAGA GCAGCTCGAA GGGGTCCCGG AGTGCTCCAG GCACCTCGCC CCGCACCTCC 
TCCTCCTCCT CCTTCTCGGA CAAGAAGCCG GCCAAGGACA AGAGCAGCAC CAGAGGGGAG 
AAGGTGAAGG CCGAGAGTGA GCCCCGGGAG GCCAAAAAGG CCCTGGAGGT GGAGGAGTCC 
AACTCAGAGG ACGAGGCCTC CTTCAAGTCC GAGTCTGCCC AGTCAAGCCC GTCCAACTCC 
AGCTCCAGCT CAGACTCCAG CTCAGACTCA GACTTCGAGC CATCCCAGAA CCACAGCCAA 
GGACCCCTGC GCTCCATGGT GGAGGACCTG CAGTCCGAGG AGTCCGACGA GGACGACTCT 
TCGTCAGGCG AGGAGGCTGC CGGCAAGACC AACCCGGGGA GGGACTCCAG GTTGAGCTTC 
AGCGACAGCG AGAGTGACAA CAGCGCCGAC TCCTCCCTGC CCAGCCGTGA GCCCCCACCC 
CCCCAGAAGC CACCCCCGCC CAACAGCAAG GTGTCAGGCC GGAGGAGCCC CGAGTCCTGC 
AGCAAGCCTG AGAAGATCCT CAAGAAGGGC ACCTACGACA AGGCCTACAC GGATGAGCTG 
GTGGAGCTAC ACCGGAGGCT GATGGCGCTG CGGGAGCGCA ACGTGCTGCA GCAGATTGTG 
AATCTGATCG AGGAGACTGG CCACTTCAAT GTCACCAACA CCACCTTCGA CTTCGACCTC 
TTCTCCCTGG ACGAGACCAC CGTGCGCAAA CTGCAGAGCT GCCTGGAGGC CGTGGCCACA 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011526323.1
CDS	16..1818
Translation	MCAFPAFPQFWDSEIPGQRHQLRSSFCVCVCTCAPVCRLDSDFKRCTVQVRLELGHRAQLRKKPTTEGFTHDWMVFVRGPEQCDIQHFVEKVVFWLHDSFPKPRRVCKEPPYKVEESGYAGFIMPIEVHFKNKEEPRKVCFTYDLFLNLEGNPPVNHLRCEKLTFNNPTTEFRYKLLRAGGVMVMPEGADTVSRPSPDYPMLPTIPLSAFSDPKKTKPSHGSKDANKESSKTSKPHKVTKEHRERPRKDSESKSSSKELEREQAKSSKDTSRKLGEGRLPKEEKAPPPKAAFKEPKMALKETKLESTSPKGGPPPPPPPPPRASSKRPATADSPKPSAKKQKKSSSKGSRSAPGTSPRTSSSSSFSDKKPAKDKSSTRGEKVKAESEPREAKKALEVEESNSEDEASFKSESAQSSPSNSSSSSDSSSDSDFEPSQNHSQGPLRSMVEDLQSEESDEDDSSSGEEAAGKTNPGRDSRLSFSDSESDNSADSSLPSREPPPPQKPPPPNSKVSGRRSPESCSKPEKILKKGTYDKAYTDELVELHRRLMALRERNVLQQIVNLIEETGHFNVTNTTFDFDLFSLDETTVRKLQSCLEAVAT

Target ORF information:

RefSeq Version	XM_011528021.1
Organism	Homo sapiens(human)
Definition	Homo sapiens MLLT1 super elongation complex subunit (MLLT1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011528021.1

ORF Insert Sequence:

ATGTGCGCGT TTCCTGCATT TCCTCAGTTC TGGGACTCTG AGATACCAGG ACAGCGCCAC 
CAACTCAGGA GCAGCTTCTG TGTCTGTGTG TGCACGTGTG CGCCTGTGTG CAGGCTGGAC 
TCTGACTTCA AAAGGTGCAC CGTCCAGGTG AGGTTAGAGC TGGGGCATCG CGCCCAACTG 
CGCAAGAAGC CCACCACGGA GGGGTTCACT CACGACTGGA TGGTGTTTGT CCGCGGCCCC 
GAGCAATGTG ACATCCAGCA CTTCGTGGAG AAGGTGGTCT TCTGGCTGCA CGACAGCTTC 
CCCAAGCCCA GACGCGTGTG CAAGGAGCCC CCCTACAAAG TAGAGGAGTC GGGGTACGCT 
GGCTTCATCA TGCCCATCGA GGTGCACTTC AAAAACAAGG AGGAGCCGAG GAAGGTCTGC 
TTCACCTACG ACCTGTTCCT GAACCTGGAA GGCAACCCGC CCGTGAACCA CCTGCGCTGC 
GAGAAGCTCA CCTTCAACAA CCCCACCACG GAGTTCCGGT ACAAGCTCCT GCGGGCCGGC 
GGGGTGATGG TAATGCCCGA AGGAGCAGAC ACGGTGTCCA GGCCCAGTCC CGACTACCCC 
ATGTTACCCA CAATTCCACT CTCTGCCTTC TCTGACCCCA AGAAGACCAA ACCATCCCAC 
GGCTCCAAGG ACGCCAACAA GGAGAGCAGC AAGACCTCCA AGCCACACAA GGTGACCAAG 
GAGCACCGGG AGCGGCCCCG CAAAGACTCC GAGAGCAAGA GCTCCTCCAA GGAGCTGGAG 
CGTGAGCAGG CCAAAAGCTC CAAGGACACC TCGCGGAAGC TGGGCGAGGG CCGGCTGCCC 
AAGGAGGAGA AGGCGCCACC GCCCAAGGCT GCCTTCAAGG AACCCAAGAT GGCCCTGAAA 
GAGACCAAGC TGGAAAGCAC GTCCCCCAAG GGTGGGCCCC CACCCCCACC CCCACCCCCA 
CCCCGGGCTT CCAGCAAGCG GCCGGCCACC GCCGACTCGC CAAAGCCCAG CGCCAAGAAG 
CAGAAGAAGA GCAGCTCGAA GGGGTCCCGG AGTGCTCCAG GCACCTCGCC CCGCACCTCC 
TCCTCCTCCT CCTTCTCGGA CAAGAAGCCG GCCAAGGACA AGAGCAGCAC CAGAGGGGAG 
AAGGTGAAGG CCGAGAGTGA GCCCCGGGAG GCCAAAAAGG CCCTGGAGGT GGAGGAGTCC 
AACTCAGAGG ACGAGGCCTC CTTCAAGTCC GAGTCTGCCC AGTCAAGCCC GTCCAACTCC 
AGCTCCAGCT CAGACTCCAG CTCAGACTCA GACTTCGAGC CATCCCAGAA CCACAGCCAA 
GGACCCCTGC GCTCCATGGT GGAGGACCTG CAGTCCGAGG AGTCCGACGA GGACGACTCT 
TCGTCAGGCG AGGAGGCTGC CGGCAAGACC AACCCGGGGA GGGACTCCAG GTTGAGCTTC 
AGCGACAGCG AGAGTGACAA CAGCGCCGAC TCCTCCCTGC CCAGCCGTGA GCCCCCACCC 
CCCCAGAAGC CACCCCCGCC CAACAGCAAG GTGTCAGGCC GGAGGAGCCC CGAGTCCTGC 
AGCAAGCCTG AGAAGATCCT CAAGAAGGGC ACCTACGACA AGGCCTACAC GGATGAGCTG 
GTGGAGCTAC ACCGGAGGCT GATGGCGCTG CGGGAGCGCA ACGTGCTGCA GCAGATTGTG 
AATCTGATCG AGGAGACTGG CCACTTCAAT GTCACCAACA CCACCTTCGA CTTCGACCTC 
TTCTCCCTGG ACGAGACCAC CGTGCGCAAA CTGCAGAGCT GCCTGGAGGC CGTGGCCACA 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MLLT1 ( XM_011528022.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_011526324.1 Homo sapiens MLLT1 super elongation complex subunit (MLLT1), transcript variant X2, mRNA.

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CloneID	OHu59001
Clone ID Related Accession (Same CDS sequence)	XM_011528022.1
Accession Version	XM_011528022.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1686bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	protein ENL isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000019.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCCAAAGA AGAGACAGTG CACCGTCCAG GTGAGGTTAG AGCTGGGGCA TCGCGCCCAA 
CTGCGCAAGA AGCCCACCAC GGAGGGGTTC ACTCACGACT GGATGGTGTT TGTCCGCGGC 
CCCGAGCAAT GTGACATCCA GCACTTCGTG GAGAAGGTGG TCTTCTGGCT GCACGACAGC 
TTCCCCAAGC CCAGACGCGT GTGCAAGGAG CCCCCCTACA AAGTAGAGGA GTCGGGGTAC 
GCTGGCTTCA TCATGCCCAT CGAGGTGCAC TTCAAAAACA AGGAGGAGCC GAGGAAGGTC 
TGCTTCACCT ACGACCTGTT CCTGAACCTG GAAGGCAACC CGCCCGTGAA CCACCTGCGC 
TGCGAGAAGC TCACCTTCAA CAACCCCACC ACGGAGTTCC GGTACAAGCT CCTGCGGGCC 
GGCGGGGTGA TGGTAATGCC CGAAGGAGCA GACACGGTGT CCAGGCCCAG TCCCGACTAC 
CCCATGTTAC CCACAATTCC ACTCTCTGCC TTCTCTGACC CCAAGAAGAC CAAACCATCC 
CACGGCTCCA AGGACGCCAA CAAGGAGAGC AGCAAGACCT CCAAGCCACA CAAGGTGACC 
AAGGAGCACC GGGAGCGGCC CCGCAAAGAC TCCGAGAGCA AGAGCTCCTC CAAGGAGCTG 
GAGCGTGAGC AGGCCAAAAG CTCCAAGGAC ACCTCGCGGA AGCTGGGCGA GGGCCGGCTG 
CCCAAGGAGG AGAAGGCGCC ACCGCCCAAG GCTGCCTTCA AGGAACCCAA GATGGCCCTG 
AAAGAGACCA AGCTGGAAAG CACGTCCCCC AAGGGTGGGC CCCCACCCCC ACCCCCACCC 
CCACCCCGGG CTTCCAGCAA GCGGCCGGCC ACCGCCGACT CGCCAAAGCC CAGCGCCAAG 
AAGCAGAAGA AGAGCAGCTC GAAGGGGTCC CGGAGTGCTC CAGGCACCTC GCCCCGCACC 
TCCTCCTCCT CCTCCTTCTC GGACAAGAAG CCGGCCAAGG ACAAGAGCAG CACCAGAGGG 
GAGAAGGTGA AGGCCGAGAG TGAGCCCCGG GAGGCCAAAA AGGCCCTGGA GGTGGAGGAG 
TCCAACTCAG AGGACGAGGC CTCCTTCAAG TCCGAGTCTG CCCAGTCAAG CCCGTCCAAC 
TCCAGCTCCA GCTCAGACTC CAGCTCAGAC TCAGACTTCG AGCCATCCCA GAACCACAGC 
CAAGGACCCC TGCGCTCCAT GGTGGAGGAC CTGCAGTCCG AGGAGTCCGA CGAGGACGAC 
TCTTCGTCAG GCGAGGAGGC TGCCGGCAAG ACCAACCCGG GGAGGGACTC CAGGTTGAGC 
TTCAGCGACA GCGAGAGTGA CAACAGCGCC GACTCCTCCC TGCCCAGCCG TGAGCCCCCA 
CCCCCCCAGA AGCCACCCCC GCCCAACAGC AAGGTGTCAG GCCGGAGGAG CCCCGAGTCC 
TGCAGCAAGC CTGAGAAGAT CCTCAAGAAG GGCACCTACG ACAAGGCCTA CACGGATGAG 
CTGGTGGAGC TACACCGGAG GCTGATGGCG CTGCGGGAGC GCAACGTGCT GCAGCAGATT 
GTGAATCTGA TCGAGGAGAC TGGCCACTTC AATGTCACCA ACACCACCTT CGACTTCGAC 
CTCTTCTCCC TGGACGAGAC CACCGTGCGC AAACTGCAGA GCTGCCTGGA GGCCGTGGCC 
ACATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011526324.1
CDS	16..1701
Translation	MPKKRQCTVQVRLELGHRAQLRKKPTTEGFTHDWMVFVRGPEQCDIQHFVEKVVFWLHDSFPKPRRVCKEPPYKVEESGYAGFIMPIEVHFKNKEEPRKVCFTYDLFLNLEGNPPVNHLRCEKLTFNNPTTEFRYKLLRAGGVMVMPEGADTVSRPSPDYPMLPTIPLSAFSDPKKTKPSHGSKDANKESSKTSKPHKVTKEHRERPRKDSESKSSSKELEREQAKSSKDTSRKLGEGRLPKEEKAPPPKAAFKEPKMALKETKLESTSPKGGPPPPPPPPPRASSKRPATADSPKPSAKKQKKSSSKGSRSAPGTSPRTSSSSSFSDKKPAKDKSSTRGEKVKAESEPREAKKALEVEESNSEDEASFKSESAQSSPSNSSSSSDSSSDSDFEPSQNHSQGPLRSMVEDLQSEESDEDDSSSGEEAAGKTNPGRDSRLSFSDSESDNSADSSLPSREPPPPQKPPPPNSKVSGRRSPESCSKPEKILKKGTYDKAYTDELVELHRRLMALRERNVLQQIVNLIEETGHFNVTNTTFDFDLFSLDETTVRKLQSCLEAVAT

Target ORF information:

RefSeq Version	XM_011528022.1
Organism	Homo sapiens(human)
Definition	Homo sapiens MLLT1 super elongation complex subunit (MLLT1), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011528022.1

ORF Insert Sequence:

ATGCCAAAGA AGAGACAGTG CACCGTCCAG GTGAGGTTAG AGCTGGGGCA TCGCGCCCAA 
CTGCGCAAGA AGCCCACCAC GGAGGGGTTC ACTCACGACT GGATGGTGTT TGTCCGCGGC 
CCCGAGCAAT GTGACATCCA GCACTTCGTG GAGAAGGTGG TCTTCTGGCT GCACGACAGC 
TTCCCCAAGC CCAGACGCGT GTGCAAGGAG CCCCCCTACA AAGTAGAGGA GTCGGGGTAC 
GCTGGCTTCA TCATGCCCAT CGAGGTGCAC TTCAAAAACA AGGAGGAGCC GAGGAAGGTC 
TGCTTCACCT ACGACCTGTT CCTGAACCTG GAAGGCAACC CGCCCGTGAA CCACCTGCGC 
TGCGAGAAGC TCACCTTCAA CAACCCCACC ACGGAGTTCC GGTACAAGCT CCTGCGGGCC 
GGCGGGGTGA TGGTAATGCC CGAAGGAGCA GACACGGTGT CCAGGCCCAG TCCCGACTAC 
CCCATGTTAC CCACAATTCC ACTCTCTGCC TTCTCTGACC CCAAGAAGAC CAAACCATCC 
CACGGCTCCA AGGACGCCAA CAAGGAGAGC AGCAAGACCT CCAAGCCACA CAAGGTGACC 
AAGGAGCACC GGGAGCGGCC CCGCAAAGAC TCCGAGAGCA AGAGCTCCTC CAAGGAGCTG 
GAGCGTGAGC AGGCCAAAAG CTCCAAGGAC ACCTCGCGGA AGCTGGGCGA GGGCCGGCTG 
CCCAAGGAGG AGAAGGCGCC ACCGCCCAAG GCTGCCTTCA AGGAACCCAA GATGGCCCTG 
AAAGAGACCA AGCTGGAAAG CACGTCCCCC AAGGGTGGGC CCCCACCCCC ACCCCCACCC 
CCACCCCGGG CTTCCAGCAA GCGGCCGGCC ACCGCCGACT CGCCAAAGCC CAGCGCCAAG 
AAGCAGAAGA AGAGCAGCTC GAAGGGGTCC CGGAGTGCTC CAGGCACCTC GCCCCGCACC 
TCCTCCTCCT CCTCCTTCTC GGACAAGAAG CCGGCCAAGG ACAAGAGCAG CACCAGAGGG 
GAGAAGGTGA AGGCCGAGAG TGAGCCCCGG GAGGCCAAAA AGGCCCTGGA GGTGGAGGAG 
TCCAACTCAG AGGACGAGGC CTCCTTCAAG TCCGAGTCTG CCCAGTCAAG CCCGTCCAAC 
TCCAGCTCCA GCTCAGACTC CAGCTCAGAC TCAGACTTCG AGCCATCCCA GAACCACAGC 
CAAGGACCCC TGCGCTCCAT GGTGGAGGAC CTGCAGTCCG AGGAGTCCGA CGAGGACGAC 
TCTTCGTCAG GCGAGGAGGC TGCCGGCAAG ACCAACCCGG GGAGGGACTC CAGGTTGAGC 
TTCAGCGACA GCGAGAGTGA CAACAGCGCC GACTCCTCCC TGCCCAGCCG TGAGCCCCCA 
CCCCCCCAGA AGCCACCCCC GCCCAACAGC AAGGTGTCAG GCCGGAGGAG CCCCGAGTCC 
TGCAGCAAGC CTGAGAAGAT CCTCAAGAAG GGCACCTACG ACAAGGCCTA CACGGATGAG 
CTGGTGGAGC TACACCGGAG GCTGATGGCG CTGCGGGAGC GCAACGTGCT GCAGCAGATT 
GTGAATCTGA TCGAGGAGAC TGGCCACTTC AATGTCACCA ACACCACCTT CGACTTCGAC 
CTCTTCTCCC TGGACGAGAC CACCGTGCGC AAACTGCAGA GCTGCCTGGA GGCCGTGGCC 
ACATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MLLT1 ( XM_011528023.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_011526325.1 Homo sapiens MLLT1 super elongation complex subunit (MLLT1), transcript variant X3, mRNA.

Price & Availability↑

CloneID	OHu59002
Clone ID Related Accession (Same CDS sequence)	XM_011528023.1
Accession Version	XM_011528023.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1677bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	protein ENL isoform X3
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000019.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTGCGCGT TTCCTGCATT TCCTCAGTTC TGGGACTCTG AGATACCAGG ACAGCGCCAC 
CAACTCAGGA GCAGCTTCTG TGTCTGTGTG TGCACGTGTG CGCCTGTGTG CAGGCTGGAC 
TCTGACTTCA AAAGGTGCAC CGTCCAGGTG AGGTTAGAGC TGGGGCATCG CGCCCAACTG 
CGCAAGAAGC CCACCACGGA GGGGTTCACT CACGACTGGA TGGTGTTTGT CCGCGGCCCC 
GAGCAATGTG ACATCCAGCA CTTCGTGGAG AAGGTGGTCT TCTGGCTGCA CGACAGCTTC 
CCCAAGCCCA GACGCGTGTG CAAGGAGCCC CCCTACAAAG TAGAGGAGTC GGGGTACGCT 
GGCTTCATCA TGCCCATCGA GGTGCACTTC AAAAACAAGG AGGAGCCGAG GAAGGTCTGC 
TTCACCTACG ACCTGTTCCT GAACCTGGAA GGCAACCCGC CCGTGAACCA CCTGCGCTGC 
GAGAAGCTCA CCTTCAACAA CCCCACCACG GAGTTCCGGT ACAAGCTCCT GCGGGCCGGC 
GGGGACGCCA ACAAGGAGAG CAGCAAGACC TCCAAGCCAC ACAAGGTGAC CAAGGAGCAC 
CGGGAGCGGC CCCGCAAAGA CTCCGAGAGC AAGAGCTCCT CCAAGGAGCT GGAGCGTGAG 
CAGGCCAAAA GCTCCAAGGA CACCTCGCGG AAGCTGGGCG AGGGCCGGCT GCCCAAGGAG 
GAGAAGGCGC CACCGCCCAA GGCTGCCTTC AAGGAACCCA AGATGGCCCT GAAAGAGACC 
AAGCTGGAAA GCACGTCCCC CAAGGGTGGG CCCCCACCCC CACCCCCACC CCCACCCCGG 
GCTTCCAGCA AGCGGCCGGC CACCGCCGAC TCGCCAAAGC CCAGCGCCAA GAAGCAGAAG 
AAGAGCAGCT CGAAGGGGTC CCGGAGTGCT CCAGGCACCT CGCCCCGCAC CTCCTCCTCC 
TCCTCCTTCT CGGACAAGAA GCCGGCCAAG GACAAGAGCA GCACCAGAGG GGAGAAGGTG 
AAGGCCGAGA GTGAGCCCCG GGAGGCCAAA AAGGCCCTGG AGGTGGAGGA GTCCAACTCA 
GAGGACGAGG CCTCCTTCAA GTCCGAGTCT GCCCAGTCAA GCCCGTCCAA CTCCAGCTCC 
AGCTCAGACT CCAGCTCAGA CTCAGACTTC GAGCCATCCC AGAACCACAG CCAAGGACCC 
CTGCGCTCCA TGGTGGAGGA CCTGCAGTCC GAGGAGTCCG ACGAGGACGA CTCTTCGTCA 
GGCGAGGAGG CTGCCGGCAA GACCAACCCG GGGAGGGACT CCAGGTTGAG CTTCAGCGAC 
AGCGAGAGTG ACAACAGCGC CGACTCCTCC CTGCCCAGCC GTGAGCCCCC ACCCCCCCAG 
AAGCCACCCC CGCCCAACAG CAAGGTGTCA GGCCGGAGGA GCCCCGAGTC CTGCAGCAAG 
CCTGAGAAGA TCCTCAAGAA GGGCACCTAC GACAAGGCCT ACACGGATGA GCTGGTGGAG 
CTACACCGGA GGCTGATGGC GCTGCGGGAG CGCAACGTGC TGCAGCAGAT TGTGAATCTG 
ATCGAGGAGA CTGGCCACTT CAATGTCACC AACACCACCT TCGACTTCGA CCTCTTCTCC 
CTGGACGAGA CCACCGTGCG CAAACTGCAG AGCTGCCTGG AGGCCGTGGC CACATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011526325.1
CDS	16..1692
Translation	MCAFPAFPQFWDSEIPGQRHQLRSSFCVCVCTCAPVCRLDSDFKRCTVQVRLELGHRAQLRKKPTTEGFTHDWMVFVRGPEQCDIQHFVEKVVFWLHDSFPKPRRVCKEPPYKVEESGYAGFIMPIEVHFKNKEEPRKVCFTYDLFLNLEGNPPVNHLRCEKLTFNNPTTEFRYKLLRAGGDANKESSKTSKPHKVTKEHRERPRKDSESKSSSKELEREQAKSSKDTSRKLGEGRLPKEEKAPPPKAAFKEPKMALKETKLESTSPKGGPPPPPPPPPRASSKRPATADSPKPSAKKQKKSSSKGSRSAPGTSPRTSSSSSFSDKKPAKDKSSTRGEKVKAESEPREAKKALEVEESNSEDEASFKSESAQSSPSNSSSSSDSSSDSDFEPSQNHSQGPLRSMVEDLQSEESDEDDSSSGEEAAGKTNPGRDSRLSFSDSESDNSADSSLPSREPPPPQKPPPPNSKVSGRRSPESCSKPEKILKKGTYDKAYTDELVELHRRLMALRERNVLQQIVNLIEETGHFNVTNTTFDFDLFSLDETTVRKLQSCLEAVAT

Target ORF information:

RefSeq Version	XM_011528023.1
Organism	Homo sapiens(human)
Definition	Homo sapiens MLLT1 super elongation complex subunit (MLLT1), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011528023.1

ORF Insert Sequence:

ATGTGCGCGT TTCCTGCATT TCCTCAGTTC TGGGACTCTG AGATACCAGG ACAGCGCCAC 
CAACTCAGGA GCAGCTTCTG TGTCTGTGTG TGCACGTGTG CGCCTGTGTG CAGGCTGGAC 
TCTGACTTCA AAAGGTGCAC CGTCCAGGTG AGGTTAGAGC TGGGGCATCG CGCCCAACTG 
CGCAAGAAGC CCACCACGGA GGGGTTCACT CACGACTGGA TGGTGTTTGT CCGCGGCCCC 
GAGCAATGTG ACATCCAGCA CTTCGTGGAG AAGGTGGTCT TCTGGCTGCA CGACAGCTTC 
CCCAAGCCCA GACGCGTGTG CAAGGAGCCC CCCTACAAAG TAGAGGAGTC GGGGTACGCT 
GGCTTCATCA TGCCCATCGA GGTGCACTTC AAAAACAAGG AGGAGCCGAG GAAGGTCTGC 
TTCACCTACG ACCTGTTCCT GAACCTGGAA GGCAACCCGC CCGTGAACCA CCTGCGCTGC 
GAGAAGCTCA CCTTCAACAA CCCCACCACG GAGTTCCGGT ACAAGCTCCT GCGGGCCGGC 
GGGGACGCCA ACAAGGAGAG CAGCAAGACC TCCAAGCCAC ACAAGGTGAC CAAGGAGCAC 
CGGGAGCGGC CCCGCAAAGA CTCCGAGAGC AAGAGCTCCT CCAAGGAGCT GGAGCGTGAG 
CAGGCCAAAA GCTCCAAGGA CACCTCGCGG AAGCTGGGCG AGGGCCGGCT GCCCAAGGAG 
GAGAAGGCGC CACCGCCCAA GGCTGCCTTC AAGGAACCCA AGATGGCCCT GAAAGAGACC 
AAGCTGGAAA GCACGTCCCC CAAGGGTGGG CCCCCACCCC CACCCCCACC CCCACCCCGG 
GCTTCCAGCA AGCGGCCGGC CACCGCCGAC TCGCCAAAGC CCAGCGCCAA GAAGCAGAAG 
AAGAGCAGCT CGAAGGGGTC CCGGAGTGCT CCAGGCACCT CGCCCCGCAC CTCCTCCTCC 
TCCTCCTTCT CGGACAAGAA GCCGGCCAAG GACAAGAGCA GCACCAGAGG GGAGAAGGTG 
AAGGCCGAGA GTGAGCCCCG GGAGGCCAAA AAGGCCCTGG AGGTGGAGGA GTCCAACTCA 
GAGGACGAGG CCTCCTTCAA GTCCGAGTCT GCCCAGTCAA GCCCGTCCAA CTCCAGCTCC 
AGCTCAGACT CCAGCTCAGA CTCAGACTTC GAGCCATCCC AGAACCACAG CCAAGGACCC 
CTGCGCTCCA TGGTGGAGGA CCTGCAGTCC GAGGAGTCCG ACGAGGACGA CTCTTCGTCA 
GGCGAGGAGG CTGCCGGCAA GACCAACCCG GGGAGGGACT CCAGGTTGAG CTTCAGCGAC 
AGCGAGAGTG ACAACAGCGC CGACTCCTCC CTGCCCAGCC GTGAGCCCCC ACCCCCCCAG 
AAGCCACCCC CGCCCAACAG CAAGGTGTCA GGCCGGAGGA GCCCCGAGTC CTGCAGCAAG 
CCTGAGAAGA TCCTCAAGAA GGGCACCTAC GACAAGGCCT ACACGGATGA GCTGGTGGAG 
CTACACCGGA GGCTGATGGC GCTGCGGGAG CGCAACGTGC TGCAGCAGAT TGTGAATCTG 
ATCGAGGAGA CTGGCCACTT CAATGTCACC AACACCACCT TCGACTTCGA CCTCTTCTCC 
CTGGACGAGA CCACCGTGCG CAAACTGCAG AGCTGCCTGG AGGCCGTGGC CACATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MLLT1 ( XM_017026819.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_016882308.1 Homo sapiens MLLT1 super elongation complex subunit (MLLT1), transcript variant X4, mRNA.

Price & Availability↑

CloneID	OHu88473
Clone ID Related Accession (Same CDS sequence)	XM_017026819.2 , XM_017026819.1
Accession Version	XM_017026819.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1584bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	protein ENL isoform X4
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000019.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_017026819.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGTGTTTG TCCGCGGCCC CGAGCAATGT GACATCCAGC ACTTCGTGGA GAAGGTGGTC 
TTCTGGCTGC ACGACAGCTT CCCCAAGCCC AGACGCGTGT GCAAGGAGCC CCCCTACAAA 
GTAGAGGAGT CGGGGTACGC TGGCTTCATC ATGCCCATCG AGGTGCACTT CAAAAACAAG 
GAGGAGCCGA GGAAGGTCTG CTTCACCTAC GACCTGTTCC TGAACCTGGA AGGCAACCCG 
CCCGTGAACC ACCTGCGCTG CGAGAAGCTC ACCTTCAACA ACCCCACCAC GGAGTTCCGG 
TACAAGCTCC TGCGGGCCGG CGGGGTGATG GTAATGCCCG AAGGAGCAGA CACGGTGTCC 
AGGCCCAGTC CCGACTACCC CATGTTACCC ACAATTCCAC TCTCTGCCTT CTCTGACCCC 
AAGAAGACCA AACCATCCCA CGGCTCCAAG GACGCCAACA AGGAGAGCAG CAAGACCTCC 
AAGCCACACA AGGTGACCAA GGAGCACCGG GAGCGGCCCC GCAAAGACTC CGAGAGCAAG 
AGCTCCTCCA AGGAGCTGGA GCGTGAGCAG GCCAAAAGCT CCAAGGACAC CTCGCGGAAG 
CTGGGCGAGG GCCGGCTGCC CAAGGAGGAG AAGGCGCCAC CGCCCAAGGC TGCCTTCAAG 
GAACCCAAGA TGGCCCTGAA AGAGACCAAG CTGGAAAGCA CGTCCCCCAA GGGTGGGCCC 
CCACCCCCAC CCCCACCCCC ACCCCGGGCT TCCAGCAAGC GGCCGGCCAC CGCCGACTCG 
CCAAAGCCCA GCGCCAAGAA GCAGAAGAAG AGCAGCTCGA AGGGGTCCCG GAGTGCTCCA 
GGCACCTCGC CCCGCACCTC CTCCTCCTCC TCCTTCTCGG ACAAGAAGCC GGCCAAGGAC 
AAGAGCAGCA CCAGAGGGGA GAAGGTGAAG GCCGAGAGTG AGCCCCGGGA GGCCAAAAAG 
GCCCTGGAGG TGGAGGAGTC CAACTCAGAG GACGAGGCCT CCTTCAAGTC CGAGTCTGCC 
CAGTCAAGCC CGTCCAACTC CAGCTCCAGC TCAGACTCCA GCTCAGACTC AGACTTCGAG 
CCATCCCAGA ACCACAGCCA AGGACCCCTG CGCTCCATGG TGGAGGACCT GCAGTCCGAG 
GAGTCCGACG AGGACGACTC TTCGTCAGGC GAGGAGGCTG CCGGCAAGAC CAACCCGGGG 
AGGGACTCCA GGTTGAGCTT CAGCGACAGC GAGAGTGACA ACAGCGCCGA CTCCTCCCTG 
CCCAGCCGTG AGCCCCCACC CCCCCAGAAG CCACCCCCGC CCAACAGCAA GGTGTCAGGC 
CGGAGGAGCC CCGAGTCCTG CAGCAAGCCT GAGAAGATCC TCAAGAAGGG CACCTACGAC 
AAGGCCTACA CGGATGAGCT GGTGGAGCTA CACCGGAGGC TGATGGCGCT GCGGGAGCGC 
AACGTGCTGC AGCAGATTGT GAATCTGATC GAGGAGACTG GCCACTTCAA TGTCACCAAC 
ACCACCTTCG ACTTCGACCT CTTCTCCCTG GACGAGACCA CCGTGCGCAA ACTGCAGAGC 
TGCCTGGAGG CCGTGGCCAC ATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016882308.1
CDS	818..2401
Translation	MVFVRGPEQCDIQHFVEKVVFWLHDSFPKPRRVCKEPPYKVEESGYAGFIMPIEVHFKNKEEPRKVCFTYDLFLNLEGNPPVNHLRCEKLTFNNPTTEFRYKLLRAGGVMVMPEGADTVSRPSPDYPMLPTIPLSAFSDPKKTKPSHGSKDANKESSKTSKPHKVTKEHRERPRKDSESKSSSKELEREQAKSSKDTSRKLGEGRLPKEEKAPPPKAAFKEPKMALKETKLESTSPKGGPPPPPPPPPRASSKRPATADSPKPSAKKQKKSSSKGSRSAPGTSPRTSSSSSFSDKKPAKDKSSTRGEKVKAESEPREAKKALEVEESNSEDEASFKSESAQSSPSNSSSSSDSSSDSDFEPSQNHSQGPLRSMVEDLQSEESDEDDSSSGEEAAGKTNPGRDSRLSFSDSESDNSADSSLPSREPPPPQKPPPPNSKVSGRRSPESCSKPEKILKKGTYDKAYTDELVELHRRLMALRERNVLQQIVNLIEETGHFNVTNTTFDFDLFSLDETTVRKLQSCLEAVAT

Target ORF information:

RefSeq Version	XM_017026819.2
Organism	Homo sapiens(human)
Definition	Homo sapiens MLLT1 super elongation complex subunit (MLLT1), transcript variant X4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017026819.2

ORF Insert Sequence:

ATGGTGTTTG TCCGCGGCCC CGAGCAATGT GACATCCAGC ACTTCGTGGA GAAGGTGGTC 
TTCTGGCTGC ACGACAGCTT CCCCAAGCCC AGACGCGTGT GCAAGGAGCC CCCCTACAAA 
GTAGAGGAGT CGGGGTACGC TGGCTTCATC ATGCCCATCG AGGTGCACTT CAAAAACAAG 
GAGGAGCCGA GGAAGGTCTG CTTCACCTAC GACCTGTTCC TGAACCTGGA AGGCAACCCG 
CCCGTGAACC ACCTGCGCTG CGAGAAGCTC ACCTTCAACA ACCCCACCAC GGAGTTCCGG 
TACAAGCTCC TGCGGGCCGG CGGGGTGATG GTAATGCCCG AAGGAGCAGA CACGGTGTCC 
AGGCCCAGTC CCGACTACCC CATGTTACCC ACAATTCCAC TCTCTGCCTT CTCTGACCCC 
AAGAAGACCA AACCATCCCA CGGCTCCAAG GACGCCAACA AGGAGAGCAG CAAGACCTCC 
AAGCCACACA AGGTGACCAA GGAGCACCGG GAGCGGCCCC GCAAAGACTC CGAGAGCAAG 
AGCTCCTCCA AGGAGCTGGA GCGTGAGCAG GCCAAAAGCT CCAAGGACAC CTCGCGGAAG 
CTGGGCGAGG GCCGGCTGCC CAAGGAGGAG AAGGCGCCAC CGCCCAAGGC TGCCTTCAAG 
GAACCCAAGA TGGCCCTGAA AGAGACCAAG CTGGAAAGCA CGTCCCCCAA GGGTGGGCCC 
CCACCCCCAC CCCCACCCCC ACCCCGGGCT TCCAGCAAGC GGCCGGCCAC CGCCGACTCG 
CCAAAGCCCA GCGCCAAGAA GCAGAAGAAG AGCAGCTCGA AGGGGTCCCG GAGTGCTCCA 
GGCACCTCGC CCCGCACCTC CTCCTCCTCC TCCTTCTCGG ACAAGAAGCC GGCCAAGGAC 
AAGAGCAGCA CCAGAGGGGA GAAGGTGAAG GCCGAGAGTG AGCCCCGGGA GGCCAAAAAG 
GCCCTGGAGG TGGAGGAGTC CAACTCAGAG GACGAGGCCT CCTTCAAGTC CGAGTCTGCC 
CAGTCAAGCC CGTCCAACTC CAGCTCCAGC TCAGACTCCA GCTCAGACTC AGACTTCGAG 
CCATCCCAGA ACCACAGCCA AGGACCCCTG CGCTCCATGG TGGAGGACCT GCAGTCCGAG 
GAGTCCGACG AGGACGACTC TTCGTCAGGC GAGGAGGCTG CCGGCAAGAC CAACCCGGGG 
AGGGACTCCA GGTTGAGCTT CAGCGACAGC GAGAGTGACA ACAGCGCCGA CTCCTCCCTG 
CCCAGCCGTG AGCCCCCACC CCCCCAGAAG CCACCCCCGC CCAACAGCAA GGTGTCAGGC 
CGGAGGAGCC CCGAGTCCTG CAGCAAGCCT GAGAAGATCC TCAAGAAGGG CACCTACGAC 
AAGGCCTACA CGGATGAGCT GGTGGAGCTA CACCGGAGGC TGATGGCGCT GCGGGAGCGC 
AACGTGCTGC AGCAGATTGT GAATCTGATC GAGGAGACTG GCCACTTCAA TGTCACCAAC 
ACCACCTTCG ACTTCGACCT CTTCTCCCTG GACGAGACCA CCGTGCGCAA ACTGCAGAGC 
TGCCTGGAGG CCGTGGCCAC ATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MLLT1 ( XM_017026819.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016882308.1 Homo sapiens myeloid/lymphoid or mixed-lineage leukemia; translocated to, 1 (MLLT1), transcript variant X4, mRNA.

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CloneID	OHu88473
Clone ID Related Accession (Same CDS sequence)	XM_017026819.2 , XM_017026819.1
Accession Version	XM_017026819.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1584bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	protein ENL isoform X4
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000019.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGTGTTTG TCCGCGGCCC CGAGCAATGT GACATCCAGC ACTTCGTGGA GAAGGTGGTC 
TTCTGGCTGC ACGACAGCTT CCCCAAGCCC AGACGCGTGT GCAAGGAGCC CCCCTACAAA 
GTAGAGGAGT CGGGGTACGC TGGCTTCATC ATGCCCATCG AGGTGCACTT CAAAAACAAG 
GAGGAGCCGA GGAAGGTCTG CTTCACCTAC GACCTGTTCC TGAACCTGGA AGGCAACCCG 
CCCGTGAACC ACCTGCGCTG CGAGAAGCTC ACCTTCAACA ACCCCACCAC GGAGTTCCGG 
TACAAGCTCC TGCGGGCCGG CGGGGTGATG GTAATGCCCG AAGGAGCAGA CACGGTGTCC 
AGGCCCAGTC CCGACTACCC CATGTTACCC ACAATTCCAC TCTCTGCCTT CTCTGACCCC 
AAGAAGACCA AACCATCCCA CGGCTCCAAG GACGCCAACA AGGAGAGCAG CAAGACCTCC 
AAGCCACACA AGGTGACCAA GGAGCACCGG GAGCGGCCCC GCAAAGACTC CGAGAGCAAG 
AGCTCCTCCA AGGAGCTGGA GCGTGAGCAG GCCAAAAGCT CCAAGGACAC CTCGCGGAAG 
CTGGGCGAGG GCCGGCTGCC CAAGGAGGAG AAGGCGCCAC CGCCCAAGGC TGCCTTCAAG 
GAACCCAAGA TGGCCCTGAA AGAGACCAAG CTGGAAAGCA CGTCCCCCAA GGGTGGGCCC 
CCACCCCCAC CCCCACCCCC ACCCCGGGCT TCCAGCAAGC GGCCGGCCAC CGCCGACTCG 
CCAAAGCCCA GCGCCAAGAA GCAGAAGAAG AGCAGCTCGA AGGGGTCCCG GAGTGCTCCA 
GGCACCTCGC CCCGCACCTC CTCCTCCTCC TCCTTCTCGG ACAAGAAGCC GGCCAAGGAC 
AAGAGCAGCA CCAGAGGGGA GAAGGTGAAG GCCGAGAGTG AGCCCCGGGA GGCCAAAAAG 
GCCCTGGAGG TGGAGGAGTC CAACTCAGAG GACGAGGCCT CCTTCAAGTC CGAGTCTGCC 
CAGTCAAGCC CGTCCAACTC CAGCTCCAGC TCAGACTCCA GCTCAGACTC AGACTTCGAG 
CCATCCCAGA ACCACAGCCA AGGACCCCTG CGCTCCATGG TGGAGGACCT GCAGTCCGAG 
GAGTCCGACG AGGACGACTC TTCGTCAGGC GAGGAGGCTG CCGGCAAGAC CAACCCGGGG 
AGGGACTCCA GGTTGAGCTT CAGCGACAGC GAGAGTGACA ACAGCGCCGA CTCCTCCCTG 
CCCAGCCGTG AGCCCCCACC CCCCCAGAAG CCACCCCCGC CCAACAGCAA GGTGTCAGGC 
CGGAGGAGCC CCGAGTCCTG CAGCAAGCCT GAGAAGATCC TCAAGAAGGG CACCTACGAC 
AAGGCCTACA CGGATGAGCT GGTGGAGCTA CACCGGAGGC TGATGGCGCT GCGGGAGCGC 
AACGTGCTGC AGCAGATTGT GAATCTGATC GAGGAGACTG GCCACTTCAA TGTCACCAAC 
ACCACCTTCG ACTTCGACCT CTTCTCCCTG GACGAGACCA CCGTGCGCAA ACTGCAGAGC 
TGCCTGGAGG CCGTGGCCAC ATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016882308.1
CDS	817..2400
Translation	MVFVRGPEQCDIQHFVEKVVFWLHDSFPKPRRVCKEPPYKVEESGYAGFIMPIEVHFKNKEEPRKVCFTYDLFLNLEGNPPVNHLRCEKLTFNNPTTEFRYKLLRAGGVMVMPEGADTVSRPSPDYPMLPTIPLSAFSDPKKTKPSHGSKDANKESSKTSKPHKVTKEHRERPRKDSESKSSSKELEREQAKSSKDTSRKLGEGRLPKEEKAPPPKAAFKEPKMALKETKLESTSPKGGPPPPPPPPPRASSKRPATADSPKPSAKKQKKSSSKGSRSAPGTSPRTSSSSSFSDKKPAKDKSSTRGEKVKAESEPREAKKALEVEESNSEDEASFKSESAQSSPSNSSSSSDSSSDSDFEPSQNHSQGPLRSMVEDLQSEESDEDDSSSGEEAAGKTNPGRDSRLSFSDSESDNSADSSLPSREPPPPQKPPPPNSKVSGRRSPESCSKPEKILKKGTYDKAYTDELVELHRRLMALRERNVLQQIVNLIEETGHFNVTNTTFDFDLFSLDETTVRKLQSCLEAVAT

Target ORF information:

RefSeq Version	XM_017026819.1
Organism	Homo sapiens(human)
Definition	Homo sapiens myeloid/lymphoid or mixed-lineage leukemia; translocated to, 1 (MLLT1), transcript variant X4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017026819.1

ORF Insert Sequence:

ATGGTGTTTG TCCGCGGCCC CGAGCAATGT GACATCCAGC ACTTCGTGGA GAAGGTGGTC 
TTCTGGCTGC ACGACAGCTT CCCCAAGCCC AGACGCGTGT GCAAGGAGCC CCCCTACAAA 
GTAGAGGAGT CGGGGTACGC TGGCTTCATC ATGCCCATCG AGGTGCACTT CAAAAACAAG 
GAGGAGCCGA GGAAGGTCTG CTTCACCTAC GACCTGTTCC TGAACCTGGA AGGCAACCCG 
CCCGTGAACC ACCTGCGCTG CGAGAAGCTC ACCTTCAACA ACCCCACCAC GGAGTTCCGG 
TACAAGCTCC TGCGGGCCGG CGGGGTGATG GTAATGCCCG AAGGAGCAGA CACGGTGTCC 
AGGCCCAGTC CCGACTACCC CATGTTACCC ACAATTCCAC TCTCTGCCTT CTCTGACCCC 
AAGAAGACCA AACCATCCCA CGGCTCCAAG GACGCCAACA AGGAGAGCAG CAAGACCTCC 
AAGCCACACA AGGTGACCAA GGAGCACCGG GAGCGGCCCC GCAAAGACTC CGAGAGCAAG 
AGCTCCTCCA AGGAGCTGGA GCGTGAGCAG GCCAAAAGCT CCAAGGACAC CTCGCGGAAG 
CTGGGCGAGG GCCGGCTGCC CAAGGAGGAG AAGGCGCCAC CGCCCAAGGC TGCCTTCAAG 
GAACCCAAGA TGGCCCTGAA AGAGACCAAG CTGGAAAGCA CGTCCCCCAA GGGTGGGCCC 
CCACCCCCAC CCCCACCCCC ACCCCGGGCT TCCAGCAAGC GGCCGGCCAC CGCCGACTCG 
CCAAAGCCCA GCGCCAAGAA GCAGAAGAAG AGCAGCTCGA AGGGGTCCCG GAGTGCTCCA 
GGCACCTCGC CCCGCACCTC CTCCTCCTCC TCCTTCTCGG ACAAGAAGCC GGCCAAGGAC 
AAGAGCAGCA CCAGAGGGGA GAAGGTGAAG GCCGAGAGTG AGCCCCGGGA GGCCAAAAAG 
GCCCTGGAGG TGGAGGAGTC CAACTCAGAG GACGAGGCCT CCTTCAAGTC CGAGTCTGCC 
CAGTCAAGCC CGTCCAACTC CAGCTCCAGC TCAGACTCCA GCTCAGACTC AGACTTCGAG 
CCATCCCAGA ACCACAGCCA AGGACCCCTG CGCTCCATGG TGGAGGACCT GCAGTCCGAG 
GAGTCCGACG AGGACGACTC TTCGTCAGGC GAGGAGGCTG CCGGCAAGAC CAACCCGGGG 
AGGGACTCCA GGTTGAGCTT CAGCGACAGC GAGAGTGACA ACAGCGCCGA CTCCTCCCTG 
CCCAGCCGTG AGCCCCCACC CCCCCAGAAG CCACCCCCGC CCAACAGCAA GGTGTCAGGC 
CGGAGGAGCC CCGAGTCCTG CAGCAAGCCT GAGAAGATCC TCAAGAAGGG CACCTACGAC 
AAGGCCTACA CGGATGAGCT GGTGGAGCTA CACCGGAGGC TGATGGCGCT GCGGGAGCGC 
AACGTGCTGC AGCAGATTGT GAATCTGATC GAGGAGACTG GCCACTTCAA TGTCACCAAC 
ACCACCTTCG ACTTCGACCT CTTCTCCCTG GACGAGACCA CCGTGCGCAA ACTGCAGAGC 
TGCCTGGAGG CCGTGGCCAC ATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

ENL links histone acetylation to oncogenic gene expression in acute myeloid leukaemia.
Nature543(7644)265-269(2017 03)
Wan L,Wen H,Li Y,Lyu J,Xi Y,Hoshii T,Joseph JK,Wang X,Loh YE,Erb MA,Souza AL,Bradner JE,Shen L,Li W,Li H,Allis CD,Armstrong SA,Shi X

MLLT1 YEATS domain mutations in clinically distinctive Favourable Histology Wilms tumours.
Nature communications610013(2015 Dec)
Perlman EJ,Gadd S,Arold ST,Radhakrishnan A,Gerhard DS,Jennings L,Huff V,Guidry Auvil JM,Davidsen TM,Dome JS,Meerzaman D,Hsu CH,Nguyen C,Anderson J,Ma Y,Mungall AJ,Moore RA,Marra MA,Mullighan CG,Ma J,Wheeler DA,Hampton OA,Gastier-Foster JM,Ross N,Smith MA

Transcriptional elongation factor ENL phosphorylated by ATM recruits polycomb and switches off transcription for DSB repair.
Molecular cell58(3)468-82(2015 May)
Ui A,Nagaura Y,Yasui A

An AF9/ENL-targted peptide with therapeutic potential in mixed lineage leukemias.
Journal of experimental therapeutics & oncology10(4)293-300(2014)
Barretto NN,Karahalios DS,You D,Hemenway CS

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MLLT1 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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