MEP1A cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	MEP1A
Entrez Gene ID	4224
Full Name	meprin A subunit alpha
Synonyms	PPHA
General protein information	Preferred Names meprin A subunit alpha Names meprin A subunit alpha N-benzoyl-L-tyrosyl-P-amino-benzoic acid hydrolase subunit alpha PABA peptide hydrolase PPH alpha bA268F1.1 (meprin A alpha (PABA peptide hydrolase)) endopeptidase-2 meprin A, alpha (PABA peptide hydrolase)
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 6 Map Location: 6p12.3
Disorder MIM:	600388

mRNA and Protein(s)

mRNA	Protein	Name
NM_005588.2	NP_005579.2	meprin A subunit alpha precursor
XM_011514629.1	XP_011512931.1	meprin A subunit alpha isoform X2
XM_011514629.2	XP_011512931.1	meprin A subunit alpha isoform X2
NM_005588.3	NP_005579.2	meprin A subunit alpha precursor
XM_011514628.1	XP_011512930.1	meprin A subunit alpha isoform X1

Pathways from BioSystems

Homologies

Bos taurus (cattle)	MEP1A	XP_003587735.2
Mus musculus (house mouse)	Mep1a	NP_032611.2
Xenopus tropicalis (tropical clawed frog)	mep1a	NP_001015767.1
Gallus gallus (chicken)	MEP1A	NP_001264650.1
	MEP1A	XP_001103444.1
Danio rerio (zebrafish)	mep1a.2	NP_001122199.1
Canis lupus familiaris (dog)	MEP1A	XP_538947.3
Rattus norvegicus (Norway rat)	Mep1a	NP_037275.1
Homo sapiens (human)	MEP1A	NP_005579.2
Pan troglodytes (chimpanzee)	MEP1A	XP_518520.3

Gene Ontology
Bibliography

Related articles in PubMed

Meprin metalloproteases: Molecular regulation and function in inflammation and fibrosis.
Arnold P, Otte A, Becker-Pauly C
Biochimica et biophysica acta1864(11 Pt B)2096-2104(2017 11)

Metalloproteinase meprin ? regulates migration and invasion of human hepatocarcinoma cells and is a mediator of the oncoprotein Reptin.
Breig O, Yates M, Neaud V, Couchy G, Grigoletto A, Lucchesi C, Prox J, Zucman-Rossi J, Becker-Pauly C, Rosenbaum J
Oncotarget8(5)7839-7851(2017 Jan)

Metalloproteases meprin-? (MEP1A) is a prognostic biomarker and promotes proliferation and invasion of colorectal cancer.
Wang X, Chen J, Wang J, Yu F, Zhao S, Zhang Y, Tang H, Peng Z
BMC cancer16383(2016 07)

Meprin metalloproteases inactivate interleukin 6.
Keiffer TR, Bond JS
The Journal of biological chemistry289(11)7580-8(2014 Mar)

Association of MEP1A gene variants with insulin metabolism in central European women with polycystic ovary syndrome.
Lam UD, Lerchbaum E, Schweighofer N, Trummer O, Eberhard K, Genser B, Pieber TR, Obermayer-Pietsch B
Gene537(2)245-52(2014 Mar)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Results showed that MEP1A expression was elevated in colorectal cancer (CRC) tissues at both the mRNA and protein levels, and provided evidence for its functionally crucial role in CRC carcinogenesis as tumor proliferation and invasion.
Title: Metalloproteases meprin-? (MEP1A) is a prognostic biomarker and promotes proliferation and invasion of colorectal cancer.

Meprin metalloproteases A and B inactivate interleukin 6
Title: Meprin metalloproteases inactivate interleukin 6.

Variants rs17468190 (G/T) in the MEP1A gene are associated with glucose and insulin metabolism in overweight/obese central European women with polycystic ovary syndrome.
Title: Association of MEP1A gene variants with insulin metabolism in central European women with polycystic ovary syndrome.

Proteolytically active meprinalpha leads to an increase in EGFR and ERK1/2 phosphorylation and subsequently enhances cell proliferation and migration
Title: Meprin? transactivates the epidermal growth factor receptor (EGFR) via ligand shedding, thereby enhancing colorectal cancer cell proliferation and migration.

The present results indicate that a TNF-alpha-mediated down-regulation of CDX2 can be related to suppressed expression of MEP1A during intestinal inflammation.
Title: TNF-?-induced down-regulation of CDX2 suppresses MEP1A expression in colitis.

The following MEP1A gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the MEP1A cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu25399	NM_005588.3 Latest version!	Homo sapiens meprin A subunit alpha (MEP1A), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$279.50-$391.30 $559.00
OHu58942	XM_011514628.1 Latest version!	Homo sapiens meprin A subunit alpha (MEP1A), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$391.30 $559.00
OHu58943	XM_011514629.2 Latest version!	Homo sapiens meprin A subunit alpha (MEP1A), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$391.30 $559.00
View Old Accession Versions >>
OHu58943	XM_011514629.1	Homo sapiens meprin A subunit alpha (MEP1A), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$391.30 $559.00
OHu25399	NM_005588.2	Homo sapiens meprin A subunit alpha (MEP1A), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$265.30 $379.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

MEP1A ( NM_005588.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_005579.2 Homo sapiens meprin A subunit alpha (MEP1A), mRNA.

Price & Availability↑

CloneID	OHu25399
Clone ID Related Accession (Same CDS sequence)	NM_005588.2 , NM_005588.3
Accession Version	NM_005588.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2241bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-26
Organism	Homo sapiens(human)
Product	meprin A subunit alpha precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DA432559.1 and AF478685.1. On Nov 23, 2018 this sequence version replaced NM_005588.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF478685.1, AK315840.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1966682, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000230588.9/ ENSP00000230588.4 RefSeq Select criteria :: based on conservation, expression ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCTTGGA TTAGATCCAC TTGCATTCTC TTTTTTACCT TGCTTTTTGC CCACATAGCA 
GCTGTACCGA TTAAGTATCT TCCTGAAGAA AATGTACATG ATGCAGATTT TGGTGAACAG 
AAGGATATTT CAGAAATCAA TTTAGCTGCA GGCTTGGACC TCTTTCAAGG GGACATCCTC 
TTGCAGAAAT CCAGAAATGG CCTGAGAGAC CCAAACACCA GGTGGACGTT CCCCATTCCT 
TACATCTTGG CTGATAATTT GGGGCTGAAT GCTAAAGGAG CCATTCTGTA TGCCTTTGAG 
ATGTTCCGTC TCAAGTCCTG TGTGGATTTC AAGCCCTATG AAGGAGAGAG CTCATATATC 
ATATTTCAAC AGTTTGATGG GTGCTGGTCT GAGGTTGGTG ACCAACATGT GGGACAGAAC 
ATTTCCATTG GCCAAGGATG TGCCTATAAG GCCATCATAG AACACGAGAT CCTGCATGCT 
TTGGGATTTT ACCACGAGCA GTCAAGGACG GACCGGGATG ATTATGTGAA CATCTGGTGG 
GACCAAATTC TTTCAGGTTA CCAGCACAAC TTTGACACCT ATGATGATAG CTTAATCACA 
GACCTCAATA CACCCTATGA TTATGAGTCT TTGATGCACT ACCAGCCTTT CTCATTTAAC 
AAGAATGCAA GTGTTCCCAC CATCACAGCC AAGATCCCTG AGTTTAACTC CATTATCGGA 
CAGCGCCTGG ATTTCAGTGC CATTGATTTA GAGAGGCTGA ACCGAATGTA CAATTGCACC 
ACAACTCACA CTCTTTTGGA CCACTGTACT TTTGAGAAGG CAAACATCTG TGGAATGATT 
CAGGGCACCA GAGATGACAC TGACTGGGCC CATCAGGACA GTGCTCAGGC TGGAGAAGTG 
GATCACACCT TGTTGGGACA ATGCACAGGT GCCGGCTACT TCATGCAGTT CAGCACCAGC 
TCGGGGTCCG CGGAAGAGGC AGCCCTACTG GAGTCTCGGA TTCTTTACCC AAAGAGGAAG 
CAGCAGTGCC TGCAATTTTT CTATAAAATG ACGGGAAGTC CTTCAGACAG ACTCGTTGTC 
TGGGTCAGGA GGGATGACAG CACAGGCAAT GTTCGCAAGT TGGTGAAGGT GCAGACTTTT 
CAAGGAGATG ATGACCACAA TTGGAAAATT GCCCATGTGG TGCTCAAAGA GGAACAGAAG 
TTTCGCTACC TTTTCCAGGG CACAAAAGGC GACCCTCAGA ACTCAACTGG GGGAATTTAC 
CTAGATGACA TCACTCTGAC AGAAACCCCC TGCCCCACAG GGGTCTGGAC AGTCCGGAAT 
TTCTCCCAAG TCCTTGAGAA CACCAGCAAA GGGGACAAGC TTCAGAGCCC TCGATTCTAC 
AATTCGGAGG GATATGGTTT TGGGGTAACT TTATACCCAA ATAGCAGAGA AAGCTCTGGT 
TACTTGAGAC TTGCTTTTCA TGTGTGCAGT GGGGAGAACG ATGCTATCCT GGAGTGGCCG 
GTAGAAAACA GACAGGTGAT AATTACCATC CTTGACCAGG AGCCTGATGT CCGGAACAGG 
ATGTCCTCAA GCATGGTGTT CACTACCTCG AAGTCGCACA CATCTCCAGC GATAAATGAC 
ACTGTCATCT GGGACAGGCC GTCCAGGGTG GGAACCTATC ATACGGACTG TAATTGTTTT 
AGAAGCATCG ACTTGGGCTG GAGTGGTTTC ATTTCCCACC AAATGCTGAA AAGGAGGAGT 
TTCCTGAAAA ATGATGACCT CATCATATTT GTGGACTTTG AAGATATCAC CCACCTCAGC 
CAGACTGAAG TTCCCACTAA AGGCAAAAGA CTGAGCCCCC AAGGCCTCAT TCTCCAAGGC 
CAGGAGCAGC AGGTCTCCGA AGAAGGTTCG GGAAAGGCCA TGTTAGAGGA AGCCCTACCT 
GTCAGCCTGA GCCAGGGGCA GCCCAGCCGA CAGAAGCGGT CGGTGGAGAA CACAGGCCCC 
CTGGAGGACC ATAACTGGCC ACAGTACTTC AGAGACCCAT GTGACCCAAA CCCTTGCCAA 
AATGACGGCA TCTGTGTGAA CGTGAAGGGG ATGGCGAGCT GCAGGTGCAT CTCTGGACAT 
GCTTTCTTCT ACACGGGGGA GCGCTGTCAG GCCGTGCAGG TGCACGGCAG TGTCCTGGGC 
ATGGTGATCG GAGGCACGGC TGGCGTGATC TTCTTGACCT TCTCCATCAT CGCCATCCTT 
TCCCAAAGGC CAAGGAAGTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_005579.2
CDS	11..2251
Translation	MAWIRSTCILFFTLLFAHIAAVPIKYLPEENVHDADFGEQKDISEINLAAGLDLFQGDILLQKSRNGLRDPNTRWTFPIPYILADNLGLNAKGAILYAFEMFRLKSCVDFKPYEGESSYIIFQQFDGCWSEVGDQHVGQNISIGQGCAYKAIIEHEILHALGFYHEQSRTDRDDYVNIWWDQILSGYQHNFDTYDDSLITDLNTPYDYESLMHYQPFSFNKNASVPTITAKIPEFNSIIGQRLDFSAIDLERLNRMYNCTTTHTLLDHCTFEKANICGMIQGTRDDTDWAHQDSAQAGEVDHTLLGQCTGAGYFMQFSTSSGSAEEAALLESRILYPKRKQQCLQFFYKMTGSPSDRLVVWVRRDDSTGNVRKLVKVQTFQGDDDHNWKIAHVVLKEEQKFRYLFQGTKGDPQNSTGGIYLDDITLTETPCPTGVWTVRNFSQVLENTSKGDKLQSPRFYNSEGYGFGVTLYPNSRESSGYLRLAFHVCSGENDAILEWPVENRQVIITILDQEPDVRNRMSSSMVFTTSKSHTSPAINDTVIWDRPSRVGTYHTDCNCFRSIDLGWSGFISHQMLKRRSFLKNDDLIIFVDFEDITHLSQTEVPTKGKRLSPQGLILQGQEQQVSEEGSGKAMLEEALPVSLSQGQPSRQKRSVENTGPLEDHNWPQYFRDPCDPNPCQNDGICVNVKGMASCRCISGHAFFYTGERCQAVQVHGSVLGMVIGGTAGVIFLTFSIIAILSQRPRK

Target ORF information:

RefSeq Version	NM_005588.3
Organism	Homo sapiens(human)
Definition	Homo sapiens meprin A subunit alpha (MEP1A), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_005588.3

ORF Insert Sequence:

ATGGCTTGGA TTAGATCCAC TTGCATTCTC TTTTTTACCT TGCTTTTTGC CCACATAGCA 
GCTGTACCGA TTAAGTATCT TCCTGAAGAA AATGTACATG ATGCAGATTT TGGTGAACAG 
AAGGATATTT CAGAAATCAA TTTAGCTGCA GGCTTGGACC TCTTTCAAGG GGACATCCTC 
TTGCAGAAAT CCAGAAATGG CCTGAGAGAC CCAAACACCA GGTGGACGTT CCCCATTCCT 
TACATCTTGG CTGATAATTT GGGGCTGAAT GCTAAAGGAG CCATTCTGTA TGCCTTTGAG 
ATGTTCCGTC TCAAGTCCTG TGTGGATTTC AAGCCCTATG AAGGAGAGAG CTCATATATC 
ATATTTCAAC AGTTTGATGG GTGCTGGTCT GAGGTTGGTG ACCAACATGT GGGACAGAAC 
ATTTCCATTG GCCAAGGATG TGCCTATAAG GCCATCATAG AACACGAGAT CCTGCATGCT 
TTGGGATTTT ACCACGAGCA GTCAAGGACG GACCGGGATG ATTATGTGAA CATCTGGTGG 
GACCAAATTC TTTCAGGTTA CCAGCACAAC TTTGACACCT ATGATGATAG CTTAATCACA 
GACCTCAATA CACCCTATGA TTATGAGTCT TTGATGCACT ACCAGCCTTT CTCATTTAAC 
AAGAATGCAA GTGTTCCCAC CATCACAGCC AAGATCCCTG AGTTTAACTC CATTATCGGA 
CAGCGCCTGG ATTTCAGTGC CATTGATTTA GAGAGGCTGA ACCGAATGTA CAATTGCACC 
ACAACTCACA CTCTTTTGGA CCACTGTACT TTTGAGAAGG CAAACATCTG TGGAATGATT 
CAGGGCACCA GAGATGACAC TGACTGGGCC CATCAGGACA GTGCTCAGGC TGGAGAAGTG 
GATCACACCT TGTTGGGACA ATGCACAGGT GCCGGCTACT TCATGCAGTT CAGCACCAGC 
TCGGGGTCCG CGGAAGAGGC AGCCCTACTG GAGTCTCGGA TTCTTTACCC AAAGAGGAAG 
CAGCAGTGCC TGCAATTTTT CTATAAAATG ACGGGAAGTC CTTCAGACAG ACTCGTTGTC 
TGGGTCAGGA GGGATGACAG CACAGGCAAT GTTCGCAAGT TGGTGAAGGT GCAGACTTTT 
CAAGGAGATG ATGACCACAA TTGGAAAATT GCCCATGTGG TGCTCAAAGA GGAACAGAAG 
TTTCGCTACC TTTTCCAGGG CACAAAAGGC GACCCTCAGA ACTCAACTGG GGGAATTTAC 
CTAGATGACA TCACTCTGAC AGAAACCCCC TGCCCCACAG GGGTCTGGAC AGTCCGGAAT 
TTCTCCCAAG TCCTTGAGAA CACCAGCAAA GGGGACAAGC TTCAGAGCCC TCGATTCTAC 
AATTCGGAGG GATATGGTTT TGGGGTAACT TTATACCCAA ATAGCAGAGA AAGCTCTGGT 
TACTTGAGAC TTGCTTTTCA TGTGTGCAGT GGGGAGAACG ATGCTATCCT GGAGTGGCCG 
GTAGAAAACA GACAGGTGAT AATTACCATC CTTGACCAGG AGCCTGATGT CCGGAACAGG 
ATGTCCTCAA GCATGGTGTT CACTACCTCG AAGTCGCACA CATCTCCAGC GATAAATGAC 
ACTGTCATCT GGGACAGGCC GTCCAGGGTG GGAACCTATC ATACGGACTG TAATTGTTTT 
AGAAGCATCG ACTTGGGCTG GAGTGGTTTC ATTTCCCACC AAATGCTGAA AAGGAGGAGT 
TTCCTGAAAA ATGATGACCT CATCATATTT GTGGACTTTG AAGATATCAC CCACCTCAGC 
CAGACTGAAG TTCCCACTAA AGGCAAAAGA CTGAGCCCCC AAGGCCTCAT TCTCCAAGGC 
CAGGAGCAGC AGGTCTCCGA AGAAGGTTCG GGAAAGGCCA TGTTAGAGGA AGCCCTACCT 
GTCAGCCTGA GCCAGGGGCA GCCCAGCCGA CAGAAGCGGT CGGTGGAGAA CACAGGCCCC 
CTGGAGGACC ATAACTGGCC ACAGTACTTC AGAGACCCAT GTGACCCAAA CCCTTGCCAA 
AATGACGGCA TCTGTGTGAA CGTGAAGGGG ATGGCGAGCT GCAGGTGCAT CTCTGGACAT 
GCTTTCTTCT ACACGGGGGA GCGCTGTCAG GCCGTGCAGG TGCACGGCAG TGTCCTGGGC 
ATGGTGATCG GAGGCACGGC TGGCGTGATC TTCTTGACCT TCTCCATCAT CGCCATCCTT 
TCCCAAAGGC CAAGGAAGTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MEP1A ( NM_005588.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_005579.2 Homo sapiens meprin A subunit alpha (MEP1A), mRNA.

Price & Availability↑

CloneID	OHu25399
Clone ID Related Accession (Same CDS sequence)	NM_005588.2 , NM_005588.3
Accession Version	NM_005588.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2241bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-23
Organism	Homo sapiens(human)
Product	meprin A subunit alpha precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DA432559.1 and AF478685.1. On Jul 24, 2007 this sequence version replaced NM_005588.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF478685.1, M82962.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1966682, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCTTGGA TTAGATCCAC TTGCATTCTC TTTTTTACCT TGCTTTTTGC CCACATAGCA 
GCTGTACCGA TTAAGTATCT TCCTGAAGAA AATGTACATG ATGCAGATTT TGGTGAACAG 
AAGGATATTT CAGAAATCAA TTTAGCTGCA GGCTTGGACC TCTTTCAAGG GGACATCCTC 
TTGCAGAAAT CCAGAAATGG CCTGAGAGAC CCAAACACCA GGTGGACGTT CCCCATTCCT 
TACATCTTGG CTGATAATTT GGGGCTGAAT GCTAAAGGAG CCATTCTGTA TGCCTTTGAG 
ATGTTCCGTC TCAAGTCCTG TGTGGATTTC AAGCCCTATG AAGGAGAGAG CTCATATATC 
ATATTTCAAC AGTTTGATGG GTGCTGGTCT GAGGTTGGTG ACCAACATGT GGGACAGAAC 
ATTTCCATTG GCCAAGGATG TGCCTATAAG GCCATCATAG AACACGAGAT CCTGCATGCT 
TTGGGATTTT ACCACGAGCA GTCAAGGACG GACCGGGATG ATTATGTGAA CATCTGGTGG 
GACCAAATTC TTTCAGGTTA CCAGCACAAC TTTGACACCT ATGATGATAG CTTAATCACA 
GACCTCAATA CACCCTATGA TTATGAGTCT TTGATGCACT ACCAGCCTTT CTCATTTAAC 
AAGAATGCAA GTGTTCCCAC CATCACAGCC AAGATCCCTG AGTTTAACTC CATTATCGGA 
CAGCGCCTGG ATTTCAGTGC CATTGATTTA GAGAGGCTGA ACCGAATGTA CAATTGCACC 
ACAACTCACA CTCTTTTGGA CCACTGTACT TTTGAGAAGG CAAACATCTG TGGAATGATT 
CAGGGCACCA GAGATGACAC TGACTGGGCC CATCAGGACA GTGCTCAGGC TGGAGAAGTG 
GATCACACCT TGTTGGGACA ATGCACAGGT GCCGGCTACT TCATGCAGTT CAGCACCAGC 
TCGGGGTCCG CGGAAGAGGC AGCCCTACTG GAGTCTCGGA TTCTTTACCC AAAGAGGAAG 
CAGCAGTGCC TGCAATTTTT CTATAAAATG ACGGGAAGTC CTTCAGACAG ACTCGTTGTC 
TGGGTCAGGA GGGATGACAG CACAGGCAAT GTTCGCAAGT TGGTGAAGGT GCAGACTTTT 
CAAGGAGATG ATGACCACAA TTGGAAAATT GCCCATGTGG TGCTCAAAGA GGAACAGAAG 
TTTCGCTACC TTTTCCAGGG CACAAAAGGC GACCCTCAGA ACTCAACTGG GGGAATTTAC 
CTAGATGACA TCACTCTGAC AGAAACCCCC TGCCCCACAG GGGTCTGGAC AGTCCGGAAT 
TTCTCCCAAG TCCTTGAGAA CACCAGCAAA GGGGACAAGC TTCAGAGCCC TCGATTCTAC 
AATTCGGAGG GATATGGTTT TGGGGTAACT TTATACCCAA ATAGCAGAGA AAGCTCTGGT 
TACTTGAGAC TTGCTTTTCA TGTGTGCAGT GGGGAGAACG ATGCTATCCT GGAGTGGCCG 
GTAGAAAACA GACAGGTGAT AATTACCATC CTTGACCAGG AGCCTGATGT CCGGAACAGG 
ATGTCCTCAA GCATGGTGTT CACTACCTCG AAGTCGCACA CATCTCCAGC GATAAATGAC 
ACTGTCATCT GGGACAGGCC GTCCAGGGTG GGAACCTATC ATACGGACTG TAATTGTTTT 
AGAAGCATCG ACTTGGGCTG GAGTGGTTTC ATTTCCCACC AAATGCTGAA AAGGAGGAGT 
TTCCTGAAAA ATGATGACCT CATCATATTT GTGGACTTTG AAGATATCAC CCACCTCAGC 
CAGACTGAAG TTCCCACTAA AGGCAAAAGA CTGAGCCCCC AAGGCCTCAT TCTCCAAGGC 
CAGGAGCAGC AGGTCTCCGA AGAAGGTTCG GGAAAGGCCA TGTTAGAGGA AGCCCTACCT 
GTCAGCCTGA GCCAGGGGCA GCCCAGCCGA CAGAAGCGGT CGGTGGAGAA CACAGGCCCC 
CTGGAGGACC ATAACTGGCC ACAGTACTTC AGAGACCCAT GTGACCCAAA CCCTTGCCAA 
AATGACGGCA TCTGTGTGAA CGTGAAGGGG ATGGCGAGCT GCAGGTGCAT CTCTGGACAT 
GCTTTCTTCT ACACGGGGGA GCGCTGTCAG GCCGTGCAGG TGCACGGCAG TGTCCTGGGC 
ATGGTGATCG GAGGCACGGC TGGCGTGATC TTCTTGACCT TCTCCATCAT CGCCATCCTT 
TCCCAAAGGC CAAGGAAGTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_005579.2
CDS	43..2283
Translation	MAWIRSTCILFFTLLFAHIAAVPIKYLPEENVHDADFGEQKDISEINLAAGLDLFQGDILLQKSRNGLRDPNTRWTFPIPYILADNLGLNAKGAILYAFEMFRLKSCVDFKPYEGESSYIIFQQFDGCWSEVGDQHVGQNISIGQGCAYKAIIEHEILHALGFYHEQSRTDRDDYVNIWWDQILSGYQHNFDTYDDSLITDLNTPYDYESLMHYQPFSFNKNASVPTITAKIPEFNSIIGQRLDFSAIDLERLNRMYNCTTTHTLLDHCTFEKANICGMIQGTRDDTDWAHQDSAQAGEVDHTLLGQCTGAGYFMQFSTSSGSAEEAALLESRILYPKRKQQCLQFFYKMTGSPSDRLVVWVRRDDSTGNVRKLVKVQTFQGDDDHNWKIAHVVLKEEQKFRYLFQGTKGDPQNSTGGIYLDDITLTETPCPTGVWTVRNFSQVLENTSKGDKLQSPRFYNSEGYGFGVTLYPNSRESSGYLRLAFHVCSGENDAILEWPVENRQVIITILDQEPDVRNRMSSSMVFTTSKSHTSPAINDTVIWDRPSRVGTYHTDCNCFRSIDLGWSGFISHQMLKRRSFLKNDDLIIFVDFEDITHLSQTEVPTKGKRLSPQGLILQGQEQQVSEEGSGKAMLEEALPVSLSQGQPSRQKRSVENTGPLEDHNWPQYFRDPCDPNPCQNDGICVNVKGMASCRCISGHAFFYTGERCQAVQVHGSVLGMVIGGTAGVIFLTFSIIAILSQRPRK

Target ORF information:

RefSeq Version	NM_005588.2
Organism	Homo sapiens(human)
Definition	Homo sapiens meprin A subunit alpha (MEP1A), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_005588.2

ORF Insert Sequence:

ATGGCTTGGA TTAGATCCAC TTGCATTCTC TTTTTTACCT TGCTTTTTGC CCACATAGCA 
GCTGTACCGA TTAAGTATCT TCCTGAAGAA AATGTACATG ATGCAGATTT TGGTGAACAG 
AAGGATATTT CAGAAATCAA TTTAGCTGCA GGCTTGGACC TCTTTCAAGG GGACATCCTC 
TTGCAGAAAT CCAGAAATGG CCTGAGAGAC CCAAACACCA GGTGGACGTT CCCCATTCCT 
TACATCTTGG CTGATAATTT GGGGCTGAAT GCTAAAGGAG CCATTCTGTA TGCCTTTGAG 
ATGTTCCGTC TCAAGTCCTG TGTGGATTTC AAGCCCTATG AAGGAGAGAG CTCATATATC 
ATATTTCAAC AGTTTGATGG GTGCTGGTCT GAGGTTGGTG ACCAACATGT GGGACAGAAC 
ATTTCCATTG GCCAAGGATG TGCCTATAAG GCCATCATAG AACACGAGAT CCTGCATGCT 
TTGGGATTTT ACCACGAGCA GTCAAGGACG GACCGGGATG ATTATGTGAA CATCTGGTGG 
GACCAAATTC TTTCAGGTTA CCAGCACAAC TTTGACACCT ATGATGATAG CTTAATCACA 
GACCTCAATA CACCCTATGA TTATGAGTCT TTGATGCACT ACCAGCCTTT CTCATTTAAC 
AAGAATGCAA GTGTTCCCAC CATCACAGCC AAGATCCCTG AGTTTAACTC CATTATCGGA 
CAGCGCCTGG ATTTCAGTGC CATTGATTTA GAGAGGCTGA ACCGAATGTA CAATTGCACC 
ACAACTCACA CTCTTTTGGA CCACTGTACT TTTGAGAAGG CAAACATCTG TGGAATGATT 
CAGGGCACCA GAGATGACAC TGACTGGGCC CATCAGGACA GTGCTCAGGC TGGAGAAGTG 
GATCACACCT TGTTGGGACA ATGCACAGGT GCCGGCTACT TCATGCAGTT CAGCACCAGC 
TCGGGGTCCG CGGAAGAGGC AGCCCTACTG GAGTCTCGGA TTCTTTACCC AAAGAGGAAG 
CAGCAGTGCC TGCAATTTTT CTATAAAATG ACGGGAAGTC CTTCAGACAG ACTCGTTGTC 
TGGGTCAGGA GGGATGACAG CACAGGCAAT GTTCGCAAGT TGGTGAAGGT GCAGACTTTT 
CAAGGAGATG ATGACCACAA TTGGAAAATT GCCCATGTGG TGCTCAAAGA GGAACAGAAG 
TTTCGCTACC TTTTCCAGGG CACAAAAGGC GACCCTCAGA ACTCAACTGG GGGAATTTAC 
CTAGATGACA TCACTCTGAC AGAAACCCCC TGCCCCACAG GGGTCTGGAC AGTCCGGAAT 
TTCTCCCAAG TCCTTGAGAA CACCAGCAAA GGGGACAAGC TTCAGAGCCC TCGATTCTAC 
AATTCGGAGG GATATGGTTT TGGGGTAACT TTATACCCAA ATAGCAGAGA AAGCTCTGGT 
TACTTGAGAC TTGCTTTTCA TGTGTGCAGT GGGGAGAACG ATGCTATCCT GGAGTGGCCG 
GTAGAAAACA GACAGGTGAT AATTACCATC CTTGACCAGG AGCCTGATGT CCGGAACAGG 
ATGTCCTCAA GCATGGTGTT CACTACCTCG AAGTCGCACA CATCTCCAGC GATAAATGAC 
ACTGTCATCT GGGACAGGCC GTCCAGGGTG GGAACCTATC ATACGGACTG TAATTGTTTT 
AGAAGCATCG ACTTGGGCTG GAGTGGTTTC ATTTCCCACC AAATGCTGAA AAGGAGGAGT 
TTCCTGAAAA ATGATGACCT CATCATATTT GTGGACTTTG AAGATATCAC CCACCTCAGC 
CAGACTGAAG TTCCCACTAA AGGCAAAAGA CTGAGCCCCC AAGGCCTCAT TCTCCAAGGC 
CAGGAGCAGC AGGTCTCCGA AGAAGGTTCG GGAAAGGCCA TGTTAGAGGA AGCCCTACCT 
GTCAGCCTGA GCCAGGGGCA GCCCAGCCGA CAGAAGCGGT CGGTGGAGAA CACAGGCCCC 
CTGGAGGACC ATAACTGGCC ACAGTACTTC AGAGACCCAT GTGACCCAAA CCCTTGCCAA 
AATGACGGCA TCTGTGTGAA CGTGAAGGGG ATGGCGAGCT GCAGGTGCAT CTCTGGACAT 
GCTTTCTTCT ACACGGGGGA GCGCTGTCAG GCCGTGCAGG TGCACGGCAG TGTCCTGGGC 
ATGGTGATCG GAGGCACGGC TGGCGTGATC TTCTTGACCT TCTCCATCAT CGCCATCCTT 
TCCCAAAGGC CAAGGAAGTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MEP1A ( XM_011514628.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_011512930.1 Homo sapiens meprin A subunit alpha (MEP1A), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu58942
Clone ID Related Accession (Same CDS sequence)	XM_011514628.1
Accession Version	XM_011514628.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2325bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	meprin A subunit alpha isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000006.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCTTGGA TTAGATCCAC TTGCATTCTC TTTTTTACCT TGCTTTTTGC CCACATAGCA 
GCTGTACCGG TAAGTCGAGT CCTGCTTTTT GGATATTTAG AAATATTAAT TCTAGTATAC 
ATTATCCATT TTCTGTATAT TTATTTTTTT CAGATTAAGT ATCTTCCTGA AGAAAATGTA 
CATGATGCAG ATTTTGGTGA ACAGAAGGAT ATTTCAGAAA TCAATTTAGC TGCAGGCTTG 
GACCTCTTTC AAGGGGACAT CCTCTTGCAG AAATCCAGAA ATGGCCTGAG AGACCCAAAC 
ACCAGGTGGA CGTTCCCCAT TCCTTACATC TTGGCTGATA ATTTGGGGCT GAATGCTAAA 
GGAGCCATTC TGTATGCCTT TGAGATGTTC CGTCTCAAGT CCTGTGTGGA TTTCAAGCCC 
TATGAAGGAG AGAGCTCATA TATCATATTT CAACAGTTTG ATGGGTGCTG GTCTGAGGTT 
GGTGACCAAC ATGTGGGACA GAACATTTCC ATTGGCCAAG GATGTGCCTA TAAGGCCATC 
ATAGAACACG AGATCCTGCA TGCTTTGGGA TTTTACCACG AGCAGTCAAG GACGGACCGG 
GATGATTATG TGAACATCTG GTGGGACCAA ATTCTTTCAG GTTACCAGCA CAACTTTGAC 
ACCTATGATG ATAGCTTAAT CACAGACCTC AATACACCCT ATGATTATGA GTCTTTGATG 
CACTACCAGC CTTTCTCATT TAACAAGAAT GCAAGTGTTC CCACCATCAC AGCCAAGATC 
CCTGAGTTTA ACTCCATTAT CGGACAGCGC CTGGATTTCA GTGCCATTGA TTTAGAGAGG 
CTGAACCGAA TGTACAATTG CACCACAACT CACACTCTTT TGGACCACTG TACTTTTGAG 
AAGGCAAACA TCTGTGGAAT GATTCAGGGC ACCAGAGATG ACACTGACTG GGCCCATCAG 
GACAGTGCTC AGGCTGGAGA AGTGGATCAC ACCTTGTTGG GACAATGCAC AGGTGCCGGC 
TACTTCATGC AGTTCAGCAC CAGCTCGGGG TCCGCGGAAG AGGCAGCCCT ACTGGAGTCT 
CGGATTCTTT ACCCAAAGAG GAAGCAGCAG TGCCTGCAAT TTTTCTATAA AATGACGGGA 
AGTCCTTCAG ACAGACTCGT TGTCTGGGTC AGGAGGGATG ACAGCACAGG CAATGTTCGC 
AAGTTGGTGA AGGTGCAGAC TTTTCAAGGA GATGATGACC ACAATTGGAA AATTGCCCAT 
GTGGTGCTCA AAGAGGAACA GAAGTTTCGC TACCTTTTCC AGGGCACAAA AGGCGACCCT 
CAGAACTCAA CTGGGGGAAT TTACCTAGAT GACATCACTC TGACAGAAAC CCCCTGCCCC 
ACAGGGGTCT GGACAGTCCG GAATTTCTCC CAAGTCCTTG AGAACACCAG CAAAGGGGAC 
AAGCTTCAGA GCCCTCGATT CTACAATTCG GAGGGATATG GTTTTGGGGT AACTTTATAC 
CCAAATAGCA GAGAAAGCTC TGGTTACTTG AGACTTGCTT TTCATGTGTG CAGTGGGGAG 
AACGATGCTA TCCTGGAGTG GCCGGTAGAA AACAGACAGG TGATAATTAC CATCCTTGAC 
CAGGAGCCTG ATGTCCGGAA CAGGATGTCC TCAAGCATGG TGTTCACTAC CTCGAAGTCG 
CACACATCTC CAGCGATAAA TGACACTGTC ATCTGGGACA GGCCGTCCAG GGTGGGAACC 
TATCATACGG ACTGTAATTG TTTTAGAAGC ATCGACTTGG GCTGGAGTGG TTTCATTTCC 
CACCAAATGC TGAAAAGGAG GAGTTTCCTG AAAAATGATG ACCTCATCAT ATTTGTGGAC 
TTTGAAGATA TCACCCACCT CAGCCAGACT GAAGTTCCCA CTAAAGGCAA AAGACTGAGC 
CCCCAAGGCC TCATTCTCCA AGGCCAGGAG CAGCAGGTCT CCGAAGAAGG TTCGGGAAAG 
GCCATGTTAG AGGAAGCCCT ACCTGTCAGC CTGAGCCAGG GGCAGCCCAG CCGACAGAAG 
CGGTCGGTGG AGAACACAGG CCCCCTGGAG GACCATAACT GGCCACAGTA CTTCAGAGAC 
CCATGTGACC CAAACCCTTG CCAAAATGAC GGCATCTGTG TGAACGTGAA GGGGATGGCG 
AGCTGCAGGT GCATCTCTGG ACATGCTTTC TTCTACACGG GGGAGCGCTG TCAGGCCGTG 
CAGGTGCACG GCAGTGTCCT GGGCATGGTG ATCGGAGGCA CGGCTGGCGT GATCTTCTTG 
ACCTTCTCCA TCATCGCCAT CCTTTCCCAA AGGCCAAGGA AGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011512930.1
CDS	16..2340
Translation	MAWIRSTCILFFTLLFAHIAAVPVSRVLLFGYLEILILVYIIHFLYIYFFQIKYLPEENVHDADFGEQKDISEINLAAGLDLFQGDILLQKSRNGLRDPNTRWTFPIPYILADNLGLNAKGAILYAFEMFRLKSCVDFKPYEGESSYIIFQQFDGCWSEVGDQHVGQNISIGQGCAYKAIIEHEILHALGFYHEQSRTDRDDYVNIWWDQILSGYQHNFDTYDDSLITDLNTPYDYESLMHYQPFSFNKNASVPTITAKIPEFNSIIGQRLDFSAIDLERLNRMYNCTTTHTLLDHCTFEKANICGMIQGTRDDTDWAHQDSAQAGEVDHTLLGQCTGAGYFMQFSTSSGSAEEAALLESRILYPKRKQQCLQFFYKMTGSPSDRLVVWVRRDDSTGNVRKLVKVQTFQGDDDHNWKIAHVVLKEEQKFRYLFQGTKGDPQNSTGGIYLDDITLTETPCPTGVWTVRNFSQVLENTSKGDKLQSPRFYNSEGYGFGVTLYPNSRESSGYLRLAFHVCSGENDAILEWPVENRQVIITILDQEPDVRNRMSSSMVFTTSKSHTSPAINDTVIWDRPSRVGTYHTDCNCFRSIDLGWSGFISHQMLKRRSFLKNDDLIIFVDFEDITHLSQTEVPTKGKRLSPQGLILQGQEQQVSEEGSGKAMLEEALPVSLSQGQPSRQKRSVENTGPLEDHNWPQYFRDPCDPNPCQNDGICVNVKGMASCRCISGHAFFYTGERCQAVQVHGSVLGMVIGGTAGVIFLTFSIIAILSQRPRK

Target ORF information:

RefSeq Version	XM_011514628.1
Organism	Homo sapiens(human)
Definition	Homo sapiens meprin A subunit alpha (MEP1A), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011514628.1

ORF Insert Sequence:

ATGGCTTGGA TTAGATCCAC TTGCATTCTC TTTTTTACCT TGCTTTTTGC CCACATAGCA 
GCTGTACCGG TAAGTCGAGT CCTGCTTTTT GGATATTTAG AAATATTAAT TCTAGTATAC 
ATTATCCATT TTCTGTATAT TTATTTTTTT CAGATTAAGT ATCTTCCTGA AGAAAATGTA 
CATGATGCAG ATTTTGGTGA ACAGAAGGAT ATTTCAGAAA TCAATTTAGC TGCAGGCTTG 
GACCTCTTTC AAGGGGACAT CCTCTTGCAG AAATCCAGAA ATGGCCTGAG AGACCCAAAC 
ACCAGGTGGA CGTTCCCCAT TCCTTACATC TTGGCTGATA ATTTGGGGCT GAATGCTAAA 
GGAGCCATTC TGTATGCCTT TGAGATGTTC CGTCTCAAGT CCTGTGTGGA TTTCAAGCCC 
TATGAAGGAG AGAGCTCATA TATCATATTT CAACAGTTTG ATGGGTGCTG GTCTGAGGTT 
GGTGACCAAC ATGTGGGACA GAACATTTCC ATTGGCCAAG GATGTGCCTA TAAGGCCATC 
ATAGAACACG AGATCCTGCA TGCTTTGGGA TTTTACCACG AGCAGTCAAG GACGGACCGG 
GATGATTATG TGAACATCTG GTGGGACCAA ATTCTTTCAG GTTACCAGCA CAACTTTGAC 
ACCTATGATG ATAGCTTAAT CACAGACCTC AATACACCCT ATGATTATGA GTCTTTGATG 
CACTACCAGC CTTTCTCATT TAACAAGAAT GCAAGTGTTC CCACCATCAC AGCCAAGATC 
CCTGAGTTTA ACTCCATTAT CGGACAGCGC CTGGATTTCA GTGCCATTGA TTTAGAGAGG 
CTGAACCGAA TGTACAATTG CACCACAACT CACACTCTTT TGGACCACTG TACTTTTGAG 
AAGGCAAACA TCTGTGGAAT GATTCAGGGC ACCAGAGATG ACACTGACTG GGCCCATCAG 
GACAGTGCTC AGGCTGGAGA AGTGGATCAC ACCTTGTTGG GACAATGCAC AGGTGCCGGC 
TACTTCATGC AGTTCAGCAC CAGCTCGGGG TCCGCGGAAG AGGCAGCCCT ACTGGAGTCT 
CGGATTCTTT ACCCAAAGAG GAAGCAGCAG TGCCTGCAAT TTTTCTATAA AATGACGGGA 
AGTCCTTCAG ACAGACTCGT TGTCTGGGTC AGGAGGGATG ACAGCACAGG CAATGTTCGC 
AAGTTGGTGA AGGTGCAGAC TTTTCAAGGA GATGATGACC ACAATTGGAA AATTGCCCAT 
GTGGTGCTCA AAGAGGAACA GAAGTTTCGC TACCTTTTCC AGGGCACAAA AGGCGACCCT 
CAGAACTCAA CTGGGGGAAT TTACCTAGAT GACATCACTC TGACAGAAAC CCCCTGCCCC 
ACAGGGGTCT GGACAGTCCG GAATTTCTCC CAAGTCCTTG AGAACACCAG CAAAGGGGAC 
AAGCTTCAGA GCCCTCGATT CTACAATTCG GAGGGATATG GTTTTGGGGT AACTTTATAC 
CCAAATAGCA GAGAAAGCTC TGGTTACTTG AGACTTGCTT TTCATGTGTG CAGTGGGGAG 
AACGATGCTA TCCTGGAGTG GCCGGTAGAA AACAGACAGG TGATAATTAC CATCCTTGAC 
CAGGAGCCTG ATGTCCGGAA CAGGATGTCC TCAAGCATGG TGTTCACTAC CTCGAAGTCG 
CACACATCTC CAGCGATAAA TGACACTGTC ATCTGGGACA GGCCGTCCAG GGTGGGAACC 
TATCATACGG ACTGTAATTG TTTTAGAAGC ATCGACTTGG GCTGGAGTGG TTTCATTTCC 
CACCAAATGC TGAAAAGGAG GAGTTTCCTG AAAAATGATG ACCTCATCAT ATTTGTGGAC 
TTTGAAGATA TCACCCACCT CAGCCAGACT GAAGTTCCCA CTAAAGGCAA AAGACTGAGC 
CCCCAAGGCC TCATTCTCCA AGGCCAGGAG CAGCAGGTCT CCGAAGAAGG TTCGGGAAAG 
GCCATGTTAG AGGAAGCCCT ACCTGTCAGC CTGAGCCAGG GGCAGCCCAG CCGACAGAAG 
CGGTCGGTGG AGAACACAGG CCCCCTGGAG GACCATAACT GGCCACAGTA CTTCAGAGAC 
CCATGTGACC CAAACCCTTG CCAAAATGAC GGCATCTGTG TGAACGTGAA GGGGATGGCG 
AGCTGCAGGT GCATCTCTGG ACATGCTTTC TTCTACACGG GGGAGCGCTG TCAGGCCGTG 
CAGGTGCACG GCAGTGTCCT GGGCATGGTG ATCGGAGGCA CGGCTGGCGT GATCTTCTTG 
ACCTTCTCCA TCATCGCCAT CCTTTCCCAA AGGCCAAGGA AGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MEP1A ( XM_011514629.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_011512931.1 Homo sapiens meprin A subunit alpha (MEP1A), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu58943
Clone ID Related Accession (Same CDS sequence)	XM_011514629.1 , XM_011514629.2
Accession Version	XM_011514629.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2118bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	meprin A subunit alpha isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000006.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCTTGGA TTAGATCCAC TTGCATTCTC TTTTTTACCT TGCTTTTTGC CCACATAGCA 
GCTGTACCGA TTAAGTATCT TCCTGAAGAA AATGTACATG ATGCAGATTT TGGTGAACAG 
AAGGATATTT CAGAAATCAA TTTAGCTGCA GGCTTGGACC TCTTTCAAGG GGACATCCTC 
TTGCAGAAAT CCAGAAATGG CCTGAGAGAC CCAAACACCA GGTGGACGTT CCCCATTCCT 
TACATCTTGG CTGATAATTT GGGGCTGAAT GCTAAAGGAG CCATTCTGTA TGCCTTTGAG 
ATGTTCCGTC TCAAGTCCTG TGTGGATTTC AAGCCCTATG AAGGAGAGAG CTCATATATC 
ATATTTCAAC AGTTTGATGG GTGCTGGTCT GAGGTTGGTG ACCAACATGT GGGACAGAAC 
ATTTCCATTG GCCAAGGATG TGCCTATAAG GCCATCATAG AACACGAGAT CCTGCATGCT 
TTGGGATTTT ACCACGAGCA GTCAAGGACG GACCGGGATG ATTATGTGAA CATCTGGTGG 
GACCAAATTC TTTCAGGTTA CCAGCACAAC TTTGACACCT ATGATGATAG CTTAATCACA 
GACCTCAATA CACCCTATGA TTATGAGTCT TTGATGCACT ACCAGCCTTT CTCATTTAAC 
AAGAATGCAA GTGTTCCCAC CATCACAGCC AAGATCCCTG AGTTTAACTC CATTATCGGA 
CAGCGCCTGG ATTTCAGTGC CATTGATTTA GAGAGGCTGA ACCGAATGTA CAATTGCACC 
ACAACTCACA CTCTTTTGGA CCACTGTACT TTTGAGAAGG CAAACATCTG TGGAATGATT 
CAGGGCACCA GAGATGACAC TGACTGGGCC CATCAGGACA GTGCTCAGGC TGGAGAAGTG 
GATCACACCT TGTTGGGACA ATGCACAGGT GCCGGCTACT TCATGCAGTT CAGCACCAGC 
TCGGGGTCCG CGGAAGAGGC AGCCCTACTG GAGTCTCGGA TTCTTTACCC AAAGAGGAAG 
CAGCAGTGCC TGCAATTTTT CTATAAAATG ACGGGAAGTC CTTCAGACAG ACTCGTTGTC 
TGGGTCAGGA GGGATGACAG CACAGGCAAT GTTCGCAAGT TGGTGAAGGT GCAGACTTTT 
CAAGGAGATG ATGACCACAA TTGGAAAATT GCCCATGTGG TGCTCAAAGA GGAACAGAAG 
TTTCGCTACC TTTTCCAGGG CACAAAAGGC GACCCTCAGA ACTCAACTGG GGGAATTTAC 
CTAGATGACA TCACTCTGAC AGAAACCCCC TGCCCCACAG GGGTCTGGAC AGTCCGGAAT 
TTCTCCCAAG TCCTTGAGAA CACCAGCAAA GGGGACAAGC TTCAGAGCCC TCGATTCTAC 
AATTCGGAGG GATATGGTTT TGGGGTAACT TTATACCCAA ATAGCAGAGA AAGCTCTGGT 
TACTTGAGAC TTGCTTTTCA TGTGTGCAGT GGGGAGAACG ATGCTATCCT GGAGTGGCCG 
GTAGAAAACA GACAGGTGAT AATTACCATC CTTGACCAGG AGCCTGATGT CCGGAACAGG 
ATGTCCTCAA GCATGGTGTT CACTACCTCG AAGTCGCACA CATCTCCAGC GATAAATGAC 
ACTGTCATCT GGGACAGGCC GTCCAGGGTG GGAACCTATC ATACGGACTG TAATTGTTTT 
AGAAGCATCG ACTTGGGCTG GAGTGGTTTC ATTTCCCACC AAATGCTGAA AAGGAGGAGT 
TTCCTGAAAA ATGATGACCT CATCATATTT GTGGACTTTG AAGATATCAC CCACCTCAGC 
CAGACTGAAG TTCCCACTAA AGGCAAAAGA CTGAGCCCCC AAGGCCTCAT TCTCCAAGGC 
CAGGAGCAGC AGGTCTCCGA AGAAGGTTCG GGAAAGGCCA TGTTAGAGGA AGCCCTACCT 
GTCAGCCTGA GCCAGGGGCA GCCCAGCCGA CAGAAGCGGT CGGTGGAGAA CACAGGCCCC 
CTGGAGGACC ATAACTGGCC ACAGTACTTC AGAGACCCAT GTGACCCAAA CCCTTGCCAA 
AATGACGGCA TCTGTGTGAA CGTGAAGGGG ATGGCGAGCT GCAGGGCCAG CATATGGCTT 
AGACTAAGCC AATCATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011512931.1
CDS	43..2160
Translation	MAWIRSTCILFFTLLFAHIAAVPIKYLPEENVHDADFGEQKDISEINLAAGLDLFQGDILLQKSRNGLRDPNTRWTFPIPYILADNLGLNAKGAILYAFEMFRLKSCVDFKPYEGESSYIIFQQFDGCWSEVGDQHVGQNISIGQGCAYKAIIEHEILHALGFYHEQSRTDRDDYVNIWWDQILSGYQHNFDTYDDSLITDLNTPYDYESLMHYQPFSFNKNASVPTITAKIPEFNSIIGQRLDFSAIDLERLNRMYNCTTTHTLLDHCTFEKANICGMIQGTRDDTDWAHQDSAQAGEVDHTLLGQCTGAGYFMQFSTSSGSAEEAALLESRILYPKRKQQCLQFFYKMTGSPSDRLVVWVRRDDSTGNVRKLVKVQTFQGDDDHNWKIAHVVLKEEQKFRYLFQGTKGDPQNSTGGIYLDDITLTETPCPTGVWTVRNFSQVLENTSKGDKLQSPRFYNSEGYGFGVTLYPNSRESSGYLRLAFHVCSGENDAILEWPVENRQVIITILDQEPDVRNRMSSSMVFTTSKSHTSPAINDTVIWDRPSRVGTYHTDCNCFRSIDLGWSGFISHQMLKRRSFLKNDDLIIFVDFEDITHLSQTEVPTKGKRLSPQGLILQGQEQQVSEEGSGKAMLEEALPVSLSQGQPSRQKRSVENTGPLEDHNWPQYFRDPCDPNPCQNDGICVNVKGMASCRASIWLRLSQS

Target ORF information:

RefSeq Version	XM_011514629.1
Organism	Homo sapiens(human)
Definition	Homo sapiens meprin A subunit alpha (MEP1A), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011514629.1

ORF Insert Sequence:

ATGGCTTGGA TTAGATCCAC TTGCATTCTC TTTTTTACCT TGCTTTTTGC CCACATAGCA 
GCTGTACCGA TTAAGTATCT TCCTGAAGAA AATGTACATG ATGCAGATTT TGGTGAACAG 
AAGGATATTT CAGAAATCAA TTTAGCTGCA GGCTTGGACC TCTTTCAAGG GGACATCCTC 
TTGCAGAAAT CCAGAAATGG CCTGAGAGAC CCAAACACCA GGTGGACGTT CCCCATTCCT 
TACATCTTGG CTGATAATTT GGGGCTGAAT GCTAAAGGAG CCATTCTGTA TGCCTTTGAG 
ATGTTCCGTC TCAAGTCCTG TGTGGATTTC AAGCCCTATG AAGGAGAGAG CTCATATATC 
ATATTTCAAC AGTTTGATGG GTGCTGGTCT GAGGTTGGTG ACCAACATGT GGGACAGAAC 
ATTTCCATTG GCCAAGGATG TGCCTATAAG GCCATCATAG AACACGAGAT CCTGCATGCT 
TTGGGATTTT ACCACGAGCA GTCAAGGACG GACCGGGATG ATTATGTGAA CATCTGGTGG 
GACCAAATTC TTTCAGGTTA CCAGCACAAC TTTGACACCT ATGATGATAG CTTAATCACA 
GACCTCAATA CACCCTATGA TTATGAGTCT TTGATGCACT ACCAGCCTTT CTCATTTAAC 
AAGAATGCAA GTGTTCCCAC CATCACAGCC AAGATCCCTG AGTTTAACTC CATTATCGGA 
CAGCGCCTGG ATTTCAGTGC CATTGATTTA GAGAGGCTGA ACCGAATGTA CAATTGCACC 
ACAACTCACA CTCTTTTGGA CCACTGTACT TTTGAGAAGG CAAACATCTG TGGAATGATT 
CAGGGCACCA GAGATGACAC TGACTGGGCC CATCAGGACA GTGCTCAGGC TGGAGAAGTG 
GATCACACCT TGTTGGGACA ATGCACAGGT GCCGGCTACT TCATGCAGTT CAGCACCAGC 
TCGGGGTCCG CGGAAGAGGC AGCCCTACTG GAGTCTCGGA TTCTTTACCC AAAGAGGAAG 
CAGCAGTGCC TGCAATTTTT CTATAAAATG ACGGGAAGTC CTTCAGACAG ACTCGTTGTC 
TGGGTCAGGA GGGATGACAG CACAGGCAAT GTTCGCAAGT TGGTGAAGGT GCAGACTTTT 
CAAGGAGATG ATGACCACAA TTGGAAAATT GCCCATGTGG TGCTCAAAGA GGAACAGAAG 
TTTCGCTACC TTTTCCAGGG CACAAAAGGC GACCCTCAGA ACTCAACTGG GGGAATTTAC 
CTAGATGACA TCACTCTGAC AGAAACCCCC TGCCCCACAG GGGTCTGGAC AGTCCGGAAT 
TTCTCCCAAG TCCTTGAGAA CACCAGCAAA GGGGACAAGC TTCAGAGCCC TCGATTCTAC 
AATTCGGAGG GATATGGTTT TGGGGTAACT TTATACCCAA ATAGCAGAGA AAGCTCTGGT 
TACTTGAGAC TTGCTTTTCA TGTGTGCAGT GGGGAGAACG ATGCTATCCT GGAGTGGCCG 
GTAGAAAACA GACAGGTGAT AATTACCATC CTTGACCAGG AGCCTGATGT CCGGAACAGG 
ATGTCCTCAA GCATGGTGTT CACTACCTCG AAGTCGCACA CATCTCCAGC GATAAATGAC 
ACTGTCATCT GGGACAGGCC GTCCAGGGTG GGAACCTATC ATACGGACTG TAATTGTTTT 
AGAAGCATCG ACTTGGGCTG GAGTGGTTTC ATTTCCCACC AAATGCTGAA AAGGAGGAGT 
TTCCTGAAAA ATGATGACCT CATCATATTT GTGGACTTTG AAGATATCAC CCACCTCAGC 
CAGACTGAAG TTCCCACTAA AGGCAAAAGA CTGAGCCCCC AAGGCCTCAT TCTCCAAGGC 
CAGGAGCAGC AGGTCTCCGA AGAAGGTTCG GGAAAGGCCA TGTTAGAGGA AGCCCTACCT 
GTCAGCCTGA GCCAGGGGCA GCCCAGCCGA CAGAAGCGGT CGGTGGAGAA CACAGGCCCC 
CTGGAGGACC ATAACTGGCC ACAGTACTTC AGAGACCCAT GTGACCCAAA CCCTTGCCAA 
AATGACGGCA TCTGTGTGAA CGTGAAGGGG ATGGCGAGCT GCAGGGCCAG CATATGGCTT 
AGACTAAGCC AATCATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MEP1A ( XM_011514629.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011512931.1 Homo sapiens meprin A subunit alpha (MEP1A), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu58943
Clone ID Related Accession (Same CDS sequence)	XM_011514629.1 , XM_011514629.2
Accession Version	XM_011514629.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2118bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	meprin A subunit alpha isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000006.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_011514629.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCTTGGA TTAGATCCAC TTGCATTCTC TTTTTTACCT TGCTTTTTGC CCACATAGCA 
GCTGTACCGA TTAAGTATCT TCCTGAAGAA AATGTACATG ATGCAGATTT TGGTGAACAG 
AAGGATATTT CAGAAATCAA TTTAGCTGCA GGCTTGGACC TCTTTCAAGG GGACATCCTC 
TTGCAGAAAT CCAGAAATGG CCTGAGAGAC CCAAACACCA GGTGGACGTT CCCCATTCCT 
TACATCTTGG CTGATAATTT GGGGCTGAAT GCTAAAGGAG CCATTCTGTA TGCCTTTGAG 
ATGTTCCGTC TCAAGTCCTG TGTGGATTTC AAGCCCTATG AAGGAGAGAG CTCATATATC 
ATATTTCAAC AGTTTGATGG GTGCTGGTCT GAGGTTGGTG ACCAACATGT GGGACAGAAC 
ATTTCCATTG GCCAAGGATG TGCCTATAAG GCCATCATAG AACACGAGAT CCTGCATGCT 
TTGGGATTTT ACCACGAGCA GTCAAGGACG GACCGGGATG ATTATGTGAA CATCTGGTGG 
GACCAAATTC TTTCAGGTTA CCAGCACAAC TTTGACACCT ATGATGATAG CTTAATCACA 
GACCTCAATA CACCCTATGA TTATGAGTCT TTGATGCACT ACCAGCCTTT CTCATTTAAC 
AAGAATGCAA GTGTTCCCAC CATCACAGCC AAGATCCCTG AGTTTAACTC CATTATCGGA 
CAGCGCCTGG ATTTCAGTGC CATTGATTTA GAGAGGCTGA ACCGAATGTA CAATTGCACC 
ACAACTCACA CTCTTTTGGA CCACTGTACT TTTGAGAAGG CAAACATCTG TGGAATGATT 
CAGGGCACCA GAGATGACAC TGACTGGGCC CATCAGGACA GTGCTCAGGC TGGAGAAGTG 
GATCACACCT TGTTGGGACA ATGCACAGGT GCCGGCTACT TCATGCAGTT CAGCACCAGC 
TCGGGGTCCG CGGAAGAGGC AGCCCTACTG GAGTCTCGGA TTCTTTACCC AAAGAGGAAG 
CAGCAGTGCC TGCAATTTTT CTATAAAATG ACGGGAAGTC CTTCAGACAG ACTCGTTGTC 
TGGGTCAGGA GGGATGACAG CACAGGCAAT GTTCGCAAGT TGGTGAAGGT GCAGACTTTT 
CAAGGAGATG ATGACCACAA TTGGAAAATT GCCCATGTGG TGCTCAAAGA GGAACAGAAG 
TTTCGCTACC TTTTCCAGGG CACAAAAGGC GACCCTCAGA ACTCAACTGG GGGAATTTAC 
CTAGATGACA TCACTCTGAC AGAAACCCCC TGCCCCACAG GGGTCTGGAC AGTCCGGAAT 
TTCTCCCAAG TCCTTGAGAA CACCAGCAAA GGGGACAAGC TTCAGAGCCC TCGATTCTAC 
AATTCGGAGG GATATGGTTT TGGGGTAACT TTATACCCAA ATAGCAGAGA AAGCTCTGGT 
TACTTGAGAC TTGCTTTTCA TGTGTGCAGT GGGGAGAACG ATGCTATCCT GGAGTGGCCG 
GTAGAAAACA GACAGGTGAT AATTACCATC CTTGACCAGG AGCCTGATGT CCGGAACAGG 
ATGTCCTCAA GCATGGTGTT CACTACCTCG AAGTCGCACA CATCTCCAGC GATAAATGAC 
ACTGTCATCT GGGACAGGCC GTCCAGGGTG GGAACCTATC ATACGGACTG TAATTGTTTT 
AGAAGCATCG ACTTGGGCTG GAGTGGTTTC ATTTCCCACC AAATGCTGAA AAGGAGGAGT 
TTCCTGAAAA ATGATGACCT CATCATATTT GTGGACTTTG AAGATATCAC CCACCTCAGC 
CAGACTGAAG TTCCCACTAA AGGCAAAAGA CTGAGCCCCC AAGGCCTCAT TCTCCAAGGC 
CAGGAGCAGC AGGTCTCCGA AGAAGGTTCG GGAAAGGCCA TGTTAGAGGA AGCCCTACCT 
GTCAGCCTGA GCCAGGGGCA GCCCAGCCGA CAGAAGCGGT CGGTGGAGAA CACAGGCCCC 
CTGGAGGACC ATAACTGGCC ACAGTACTTC AGAGACCCAT GTGACCCAAA CCCTTGCCAA 
AATGACGGCA TCTGTGTGAA CGTGAAGGGG ATGGCGAGCT GCAGGGCCAG CATATGGCTT 
AGACTAAGCC AATCATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011512931.1
CDS	14..2131
Translation	MAWIRSTCILFFTLLFAHIAAVPIKYLPEENVHDADFGEQKDISEINLAAGLDLFQGDILLQKSRNGLRDPNTRWTFPIPYILADNLGLNAKGAILYAFEMFRLKSCVDFKPYEGESSYIIFQQFDGCWSEVGDQHVGQNISIGQGCAYKAIIEHEILHALGFYHEQSRTDRDDYVNIWWDQILSGYQHNFDTYDDSLITDLNTPYDYESLMHYQPFSFNKNASVPTITAKIPEFNSIIGQRLDFSAIDLERLNRMYNCTTTHTLLDHCTFEKANICGMIQGTRDDTDWAHQDSAQAGEVDHTLLGQCTGAGYFMQFSTSSGSAEEAALLESRILYPKRKQQCLQFFYKMTGSPSDRLVVWVRRDDSTGNVRKLVKVQTFQGDDDHNWKIAHVVLKEEQKFRYLFQGTKGDPQNSTGGIYLDDITLTETPCPTGVWTVRNFSQVLENTSKGDKLQSPRFYNSEGYGFGVTLYPNSRESSGYLRLAFHVCSGENDAILEWPVENRQVIITILDQEPDVRNRMSSSMVFTTSKSHTSPAINDTVIWDRPSRVGTYHTDCNCFRSIDLGWSGFISHQMLKRRSFLKNDDLIIFVDFEDITHLSQTEVPTKGKRLSPQGLILQGQEQQVSEEGSGKAMLEEALPVSLSQGQPSRQKRSVENTGPLEDHNWPQYFRDPCDPNPCQNDGICVNVKGMASCRASIWLRLSQS

Target ORF information:

RefSeq Version	XM_011514629.2
Organism	Homo sapiens(human)
Definition	Homo sapiens meprin A subunit alpha (MEP1A), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011514629.2

ORF Insert Sequence:

ATGGCTTGGA TTAGATCCAC TTGCATTCTC TTTTTTACCT TGCTTTTTGC CCACATAGCA 
GCTGTACCGA TTAAGTATCT TCCTGAAGAA AATGTACATG ATGCAGATTT TGGTGAACAG 
AAGGATATTT CAGAAATCAA TTTAGCTGCA GGCTTGGACC TCTTTCAAGG GGACATCCTC 
TTGCAGAAAT CCAGAAATGG CCTGAGAGAC CCAAACACCA GGTGGACGTT CCCCATTCCT 
TACATCTTGG CTGATAATTT GGGGCTGAAT GCTAAAGGAG CCATTCTGTA TGCCTTTGAG 
ATGTTCCGTC TCAAGTCCTG TGTGGATTTC AAGCCCTATG AAGGAGAGAG CTCATATATC 
ATATTTCAAC AGTTTGATGG GTGCTGGTCT GAGGTTGGTG ACCAACATGT GGGACAGAAC 
ATTTCCATTG GCCAAGGATG TGCCTATAAG GCCATCATAG AACACGAGAT CCTGCATGCT 
TTGGGATTTT ACCACGAGCA GTCAAGGACG GACCGGGATG ATTATGTGAA CATCTGGTGG 
GACCAAATTC TTTCAGGTTA CCAGCACAAC TTTGACACCT ATGATGATAG CTTAATCACA 
GACCTCAATA CACCCTATGA TTATGAGTCT TTGATGCACT ACCAGCCTTT CTCATTTAAC 
AAGAATGCAA GTGTTCCCAC CATCACAGCC AAGATCCCTG AGTTTAACTC CATTATCGGA 
CAGCGCCTGG ATTTCAGTGC CATTGATTTA GAGAGGCTGA ACCGAATGTA CAATTGCACC 
ACAACTCACA CTCTTTTGGA CCACTGTACT TTTGAGAAGG CAAACATCTG TGGAATGATT 
CAGGGCACCA GAGATGACAC TGACTGGGCC CATCAGGACA GTGCTCAGGC TGGAGAAGTG 
GATCACACCT TGTTGGGACA ATGCACAGGT GCCGGCTACT TCATGCAGTT CAGCACCAGC 
TCGGGGTCCG CGGAAGAGGC AGCCCTACTG GAGTCTCGGA TTCTTTACCC AAAGAGGAAG 
CAGCAGTGCC TGCAATTTTT CTATAAAATG ACGGGAAGTC CTTCAGACAG ACTCGTTGTC 
TGGGTCAGGA GGGATGACAG CACAGGCAAT GTTCGCAAGT TGGTGAAGGT GCAGACTTTT 
CAAGGAGATG ATGACCACAA TTGGAAAATT GCCCATGTGG TGCTCAAAGA GGAACAGAAG 
TTTCGCTACC TTTTCCAGGG CACAAAAGGC GACCCTCAGA ACTCAACTGG GGGAATTTAC 
CTAGATGACA TCACTCTGAC AGAAACCCCC TGCCCCACAG GGGTCTGGAC AGTCCGGAAT 
TTCTCCCAAG TCCTTGAGAA CACCAGCAAA GGGGACAAGC TTCAGAGCCC TCGATTCTAC 
AATTCGGAGG GATATGGTTT TGGGGTAACT TTATACCCAA ATAGCAGAGA AAGCTCTGGT 
TACTTGAGAC TTGCTTTTCA TGTGTGCAGT GGGGAGAACG ATGCTATCCT GGAGTGGCCG 
GTAGAAAACA GACAGGTGAT AATTACCATC CTTGACCAGG AGCCTGATGT CCGGAACAGG 
ATGTCCTCAA GCATGGTGTT CACTACCTCG AAGTCGCACA CATCTCCAGC GATAAATGAC 
ACTGTCATCT GGGACAGGCC GTCCAGGGTG GGAACCTATC ATACGGACTG TAATTGTTTT 
AGAAGCATCG ACTTGGGCTG GAGTGGTTTC ATTTCCCACC AAATGCTGAA AAGGAGGAGT 
TTCCTGAAAA ATGATGACCT CATCATATTT GTGGACTTTG AAGATATCAC CCACCTCAGC 
CAGACTGAAG TTCCCACTAA AGGCAAAAGA CTGAGCCCCC AAGGCCTCAT TCTCCAAGGC 
CAGGAGCAGC AGGTCTCCGA AGAAGGTTCG GGAAAGGCCA TGTTAGAGGA AGCCCTACCT 
GTCAGCCTGA GCCAGGGGCA GCCCAGCCGA CAGAAGCGGT CGGTGGAGAA CACAGGCCCC 
CTGGAGGACC ATAACTGGCC ACAGTACTTC AGAGACCCAT GTGACCCAAA CCCTTGCCAA 
AATGACGGCA TCTGTGTGAA CGTGAAGGGG ATGGCGAGCT GCAGGGCCAG CATATGGCTT 
AGACTAAGCC AATCATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Meprin metalloproteases: Molecular regulation and function in inflammation and fibrosis.
Biochimica et biophysica acta1864(11 Pt B)2096-2104(2017 11)
Arnold P,Otte A,Becker-Pauly C

Metalloproteinase meprin ? regulates migration and invasion of human hepatocarcinoma cells and is a mediator of the oncoprotein Reptin.
Oncotarget8(5)7839-7851(2017 Jan)
Breig O,Yates M,Neaud V,Couchy G,Grigoletto A,Lucchesi C,Prox J,Zucman-Rossi J,Becker-Pauly C,Rosenbaum J

Metalloproteases meprin-? (MEP1A) is a prognostic biomarker and promotes proliferation and invasion of colorectal cancer.
BMC cancer16383(2016 07)
Wang X,Chen J,Wang J,Yu F,Zhao S,Zhang Y,Tang H,Peng Z

Meprin metalloproteases inactivate interleukin 6.
The Journal of biological chemistry289(11)7580-8(2014 Mar)
Keiffer TR,Bond JS

Association of MEP1A gene variants with insulin metabolism in central European women with polycystic ovary syndrome.
Gene537(2)245-52(2014 Mar)
Lam UD,Lerchbaum E,Schweighofer N,Trummer O,Eberhard K,Genser B,Pieber TR,Obermayer-Pietsch B

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MEP1A cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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