ITIH1 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	ITIH1
Entrez Gene ID	3697
Full Name	inter-alpha-trypsin inhibitor heavy chain 1
Synonyms	H1P,IATIH,IGHEP1,ITI-HC1,ITIH,SHAP
General protein information	Preferred Names inter-alpha-trypsin inhibitor heavy chain 1 Names inter-alpha-trypsin inhibitor heavy chain H1 ITI heavy chain H1 inter-alpha (globulin) inhibitor, H1 polypeptide inter-alpha-inhibitor heavy chain 1 inter-alpha-trypsin inhibitor complex component III serum-derived hyaluronan-associated protein
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 3 Map Location: 3p21.1
Summary	This gene encodes a member of the inter-alpha-trypsin inhibitor family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the heavy chain of the inter-alpha-trypsin inhibitor complex, which is secreted by hepatocytes into the blood. The heavy chain also interacts with hyaluronan, and this interaction may play a role in ovulation and fertilization, and has been implicated in multiple inflammatory diseases. This gene is present in a gene cluster on chromosome 3. [provided by RefSeq, Nov 2015].
Disorder MIM:	147270

mRNA and Protein(s)

mRNA	Protein	Name
NM_002215.3	NP_002206.2	inter-alpha-trypsin inhibitor heavy chain H1 isoform a preproprotein
NM_001166434.2	NP_001159906.1	inter-alpha-trypsin inhibitor heavy chain H1 isoform b
NM_001166434.3	NP_001159906.1	inter-alpha-trypsin inhibitor heavy chain H1 isoform b
NM_002215.4	NP_002206.2	inter-alpha-trypsin inhibitor heavy chain H1 isoform a preproprotein
NM_001166435.2	NP_001159907.1	inter-alpha-trypsin inhibitor heavy chain H1 isoform c
NM_001166436.2	NP_001159908.1	inter-alpha-trypsin inhibitor heavy chain H1 isoform c

Pathways from BioSystems

Homologies

Homo sapiens (human)	ITIH1	NP_002206.2
Pan troglodytes (chimpanzee)	ITIH1	XP_001172464.1
Mus musculus (house mouse)	Itih1	NP_032432.2
Rattus norvegicus (Norway rat)	Itih1	NP_001100761.2
	ITIH1	XP_001084712.1
Canis lupus familiaris (dog)	LOC476590	XP_533794.2
Bos taurus (cattle)	ITIH1	NP_001068821.1

Gene Ontology
Bibliography

Related articles in PubMed

Characterization of the Extracellular Matrix of Normal and Diseased Tissues Using Proteomics.
Naba A, Pearce OMT, Del Rosario A, Ma D, Ding H, Rajeeve V, Cutillas PR, Balkwill FR, Hynes RO
Journal of proteome research16(8)3083-3091(2017 Aug)

Thrombin Cleavage of Inter-?-inhibitor Heavy Chain 1 Regulates Leukocyte Binding to an Inflammatory Hyaluronan Matrix.
Petrey AC, de la Motte CA
The Journal of biological chemistry291(47)24324-24334(2016 Nov)

The Compact and Biologically Relevant Structure of Inter-?-inhibitor Is Maintained by the Chondroitin Sulfate Chain and Divalent Cations.
Scavenius C, Nikolajsen CL, Stenvang M, Th?gersen IB, Wyro?emski ?, Wisniewski HG, Otzen DE, Sanggaard KW, Enghild JJ
The Journal of biological chemistry291(9)4658-70(2016 Feb)

Common variants near ABCA1, AFAP1 and GMDS confer risk of primary open-angle glaucoma.
Gharahkhani P, Burdon KP, Fogarty R, Sharma S, Hewitt AW, Martin S, Law MH, Cremin K, Bailey JNC, Loomis SJ, Pasquale LR, Haines JL, Hauser MA, Viswanathan AC, McGuffin P, Topouzis F, Foster PJ, Graham SL, Casson RJ, Chehade M, White AJ, Zhou T, Souzeau E, Landers J, Fitzgerald JT, Klebe S, Ruddle JB, Goldberg I, Healey PR, , Mills RA, Wang JJ, Montgomery GW, Martin NG, RadfordSmith G, Whiteman DC, Brown MA, Wiggs JL, Mackey DA, Mitchell P, MacGregor S, Craig JE
Nature genetics46(10)1120-1125(2014 Oct)

Biological insights from 108 schizophrenia-associated genetic loci.

Nature511(7510)421-7(2014 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Furthermore, thrombin treatment of the inflammatory matrix leads to dissolution of HC-HA cable structures and abolishes leukocyte adhesion. These data establish a novel mechanism whereby thrombin cleavage of HC1 regulates the adhesive properties of an inflammatory HA matrix.
Title: Thrombin Cleavage of Inter-?-inhibitor Heavy Chain 1 Regulates Leukocyte Binding to an Inflammatory Hyaluronan Matrix.

Data suggest that Mg2+ or Mn2+ (but not Ca2+) induce a conformational change in inter-alpha-inhibitor (ITIH1 and ITIH2) and a bikunin/chondroitin sulfate-dependent increase in thermodynamic stability; bikunin binds adjacent to the two heavy chains.
Title: The Compact and Biologically Relevant Structure of Inter-?-inhibitor Is Maintained by the Chondroitin Sulfate Chain and Divalent Cations.

The results of this study revealed that the shared genetic risk factors of both schizophrenia and major depressive disorder exist in ITIH family genes in the Han Chinese population.
Title: ITIH family genes confer risk to schizophrenia and major depressive disorder in the Han Chinese population.

Data indicate that TSG-6-mediated cross-linking of hyaluronan (HA) films is impaired in the presence of inter-alpha-inhibitor (IalphaI) and that this effect suppresses the TSG-6-mediated enhancement of HA binding to CD44-positive cells.
Title: Inter-?-inhibitor impairs TSG-6-induced hyaluronan cross-linking.

Human inter-alpha-inhibitor is a substrate for factor XIIIa and tissue transglutaminase.
Title: Human inter-?-inhibitor is a substrate for factor XIIIa and tissue transglutaminase.

The following ITIH1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ITIH1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu20775	NM_001166435.2 Latest version!	Homo sapiens inter-alpha-trypsin inhibitor heavy chain 1 (ITIH1), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$265.30 $379.00
OHu20775	NM_001166436.2 Latest version!	Homo sapiens inter-alpha-trypsin inhibitor heavy chain 1 (ITIH1), transcript variant 4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$265.30 $379.00
OHu20213	NM_002215.4 Latest version!	Homo sapiens inter-alpha-trypsin inhibitor heavy chain 1 (ITIH1), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$265.30 $379.00
OHu21901	NM_001166434.3 Latest version!	Homo sapiens inter-alpha-trypsin inhibitor heavy chain 1 (ITIH1), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$265.30 $379.00
View Old Accession Versions >>
OHu21901	NM_001166434.2	Homo sapiens inter-alpha-trypsin inhibitor heavy chain 1 (ITIH1), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$265.30 $379.00
OHu20213	NM_002215.3	Homo sapiens inter-alpha-trypsin inhibitor heavy chain 1 (ITIH1), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$265.30 $379.00
Hide Old Accession Versions >>

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***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

ITIH1 ( NM_001166435.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001159907.1 Homo sapiens inter-alpha-trypsin inhibitor heavy chain 1 (ITIH1), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu20775
Clone ID Related Accession (Same CDS sequence)	NM_001166435.2 , NM_001166436.2
Accession Version	NM_001166435.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1872bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-22
Organism	Homo sapiens(human)
Product	inter-alpha-trypsin inhibitor heavy chain H1 isoform c
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK303156.1, AC006254.10 and AA897466.1. On Oct 28, 2011 this sequence version replaced NM_001166435.1. Transcript Variant: This variant (3) differs in the 5' UTR and coding sequence compared to variant 1. The resulting isoform (c) has a shorter N-terminus and lacks a predicted signal peptide compared to isoform a. Both variants 3 and 4 ncode isoform c. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK303156.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01820693 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAACAAGA ACGTGGTTTT TGTGATTGAC ATCAGTGGCT CCATGAGAGG CCAGAAAGTG 
AAGCAGACCA AGGAGGCACT CCTTAAAATT CTGGGGGACA TGCAGCCAGG GGACTACTTT 
GACCTGGTTC TTTTTGGGAC TCGAGTACAA TCGTGGAAGG GCTCGCTGGT GCAAGCATCT 
GAGGCCAACC TACAAGCAGC TCAAGACTTT GTGCGGGGCT TTTCCCTGGA TGAGGCCACA 
AACCTGAATG GAGGTTTGCT CCGGGGAATT GAGATCTTGA ACCAAGTTCA GGAAAGCCTC 
CCAGAACTCA GCAACCATGC CTCAATACTC ATCATGTTGA CAGATGGCGA TCCCACAGAG 
GGGGTGACGG ACCGTTCCCA AATCCTCAAG AACGTCCGCA ACGCCATCCG GGGCAGGTTC 
CCGCTCTACA ACCTGGGTTT CGGCCACAAT GTGGACTTTA ACTTTCTGGA GGTCATGTCC 
ATGGAGAACA ACGGACGGGC CCAGAGAATC TACGAGGACC ATGATGCCAC CCAGCAGCTG 
CAGGGTTTCT ACAGCCAGGT AGCCAAACCC CTGCTGGTGG ATGTGGATTT GCAGTACCCC 
CAGGATGCTG TCTTGGCCCT GACCCAGAAC CACCATAAAC AGTACTACGA AGGCTCAGAG 
ATTGTGGTGG CCGGGCGCAT TGCTGACAAC AAACAGAGCA GCTTCAAGGC TGATGTGCAG 
GCCCATGGGG AGGGACAAGA ATTCAGTATA ACCTGCCTAG TGGATGAGGA GGAGATGAAG 
AAACTGCTCC GAGAGCGTGG CCACATGCTG GAGAACCACG TCGAGCGCCT CTGGGCCTAC 
CTCACCATCC AGGAGCTGCT GGCCAAGCGG ATGAAGGTGG ACAGGGAGGA GAGGGCCAAC 
CTGTCATCCC AGGCCCTGCA GATGTCGCTG GACTATGGGT TTGTGACCCC ACTGACCTCC 
ATGAGCATCA GGGGCATGGC GGACCAGGAC GGCCTGAAGC CCACCATCGA CAAGCCCTCA 
GAGGATTCTC CGCCTTTGGA GATGCTGGGA CCCAGAAGGA CGTTCGTGCT GTCAGCCTTG 
CAGCCTTCTC CTACTCATTC CAGCTCCAAT ACCCAGCGGC TGCCAGACCG AGTGACCGGC 
GTGGACACAG ACCCTCACTT CATCATCCAC GTGCCCCAGA AAGAGGACAC CCTGTGCTTC 
AACATCAATG AGGAGCCTGG TGTTATCCTG AGCCTGGTAC AGGACCCCAA CACAGGCTTC 
TCAGTGAATG GACAGCTCAT TGGCAACAAG GCCAGGAGCC CTGGGCAGCA TGACGGCACG 
TACTTCGGGC GGCTGGGAAT CGCAAACCCT GCCACGGACT TTCAGTTGGA AGTGACTCCT 
CAGAACATTA CGCTGAACCC CGGCTTTGGT GGGCCTGTGT TTTCCTGGAG GGACCAAGCT 
GTGCTGCGGC AGGACGGGGT GGTGGTGACC ATCAACAAGA AGAGGAACCT GGTGGTGTCT 
GTGGACGACG GTGGCACCTT TGAGGTTGTT TTGCACCGAG TGTGGAAGGG GAGCTCGGTC 
CACCAGGACT TCCTGGGCTT CTATGTGCTG GACAGTCATC GGATGTCAGC CCGGACGCAC 
GGGCTGCTGG GGCAATTTTT CCACCCCATC GGTTTTGAAG TGTCTGACAT CCACCCAGGC 
TCTGACCCCA CAAAGCCAGA TGCCACGATG GTGGTGAGGA ACCGCCGGCT CACGGTCACC 
AGGGGTTTGC AAAAAGACTA CAGCAAGGAC CCGTGGCATG GGGCCGAGGT GTCCTGCTGG 
TTCATTCACA ACAATGGGGC TGGACTCATC GATGGTGCCT ACACTGATTA TATCGTCCCC 
GACATCTTCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001159907.1
CDS	465..2336
Translation	MNKNVVFVIDISGSMRGQKVKQTKEALLKILGDMQPGDYFDLVLFGTRVQSWKGSLVQASEANLQAAQDFVRGFSLDEATNLNGGLLRGIEILNQVQESLPELSNHASILIMLTDGDPTEGVTDRSQILKNVRNAIRGRFPLYNLGFGHNVDFNFLEVMSMENNGRAQRIYEDHDATQQLQGFYSQVAKPLLVDVDLQYPQDAVLALTQNHHKQYYEGSEIVVAGRIADNKQSSFKADVQAHGEGQEFSITCLVDEEEMKKLLRERGHMLENHVERLWAYLTIQELLAKRMKVDREERANLSSQALQMSLDYGFVTPLTSMSIRGMADQDGLKPTIDKPSEDSPPLEMLGPRRTFVLSALQPSPTHSSSNTQRLPDRVTGVDTDPHFIIHVPQKEDTLCFNINEEPGVILSLVQDPNTGFSVNGQLIGNKARSPGQHDGTYFGRLGIANPATDFQLEVTPQNITLNPGFGGPVFSWRDQAVLRQDGVVVTINKKRNLVVSVDDGGTFEVVLHRVWKGSSVHQDFLGFYVLDSHRMSARTHGLLGQFFHPIGFEVSDIHPGSDPTKPDATMVVRNRRLTVTRGLQKDYSKDPWHGAEVSCWFIHNNGAGLIDGAYTDYIVPDIF

Target ORF information:

RefSeq Version	NM_001166435.2
Organism	Homo sapiens(human)
Definition	Homo sapiens inter-alpha-trypsin inhibitor heavy chain 1 (ITIH1), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001166435.2

ORF Insert Sequence:

ATGAACAAGA ACGTGGTTTT TGTGATTGAC ATCAGTGGCT CCATGAGAGG CCAGAAAGTG 
AAGCAGACCA AGGAGGCACT CCTTAAAATT CTGGGGGACA TGCAGCCAGG GGACTACTTT 
GACCTGGTTC TTTTTGGGAC TCGAGTACAA TCGTGGAAGG GCTCGCTGGT GCAAGCATCT 
GAGGCCAACC TACAAGCAGC TCAAGACTTT GTGCGGGGCT TTTCCCTGGA TGAGGCCACA 
AACCTGAATG GAGGTTTGCT CCGGGGAATT GAGATCTTGA ACCAAGTTCA GGAAAGCCTC 
CCAGAACTCA GCAACCATGC CTCAATACTC ATCATGTTGA CAGATGGCGA TCCCACAGAG 
GGGGTGACGG ACCGTTCCCA AATCCTCAAG AACGTCCGCA ACGCCATCCG GGGCAGGTTC 
CCGCTCTACA ACCTGGGTTT CGGCCACAAT GTGGACTTTA ACTTTCTGGA GGTCATGTCC 
ATGGAGAACA ACGGACGGGC CCAGAGAATC TACGAGGACC ATGATGCCAC CCAGCAGCTG 
CAGGGTTTCT ACAGCCAGGT AGCCAAACCC CTGCTGGTGG ATGTGGATTT GCAGTACCCC 
CAGGATGCTG TCTTGGCCCT GACCCAGAAC CACCATAAAC AGTACTACGA AGGCTCAGAG 
ATTGTGGTGG CCGGGCGCAT TGCTGACAAC AAACAGAGCA GCTTCAAGGC TGATGTGCAG 
GCCCATGGGG AGGGACAAGA ATTCAGTATA ACCTGCCTAG TGGATGAGGA GGAGATGAAG 
AAACTGCTCC GAGAGCGTGG CCACATGCTG GAGAACCACG TCGAGCGCCT CTGGGCCTAC 
CTCACCATCC AGGAGCTGCT GGCCAAGCGG ATGAAGGTGG ACAGGGAGGA GAGGGCCAAC 
CTGTCATCCC AGGCCCTGCA GATGTCGCTG GACTATGGGT TTGTGACCCC ACTGACCTCC 
ATGAGCATCA GGGGCATGGC GGACCAGGAC GGCCTGAAGC CCACCATCGA CAAGCCCTCA 
GAGGATTCTC CGCCTTTGGA GATGCTGGGA CCCAGAAGGA CGTTCGTGCT GTCAGCCTTG 
CAGCCTTCTC CTACTCATTC CAGCTCCAAT ACCCAGCGGC TGCCAGACCG AGTGACCGGC 
GTGGACACAG ACCCTCACTT CATCATCCAC GTGCCCCAGA AAGAGGACAC CCTGTGCTTC 
AACATCAATG AGGAGCCTGG TGTTATCCTG AGCCTGGTAC AGGACCCCAA CACAGGCTTC 
TCAGTGAATG GACAGCTCAT TGGCAACAAG GCCAGGAGCC CTGGGCAGCA TGACGGCACG 
TACTTCGGGC GGCTGGGAAT CGCAAACCCT GCCACGGACT TTCAGTTGGA AGTGACTCCT 
CAGAACATTA CGCTGAACCC CGGCTTTGGT GGGCCTGTGT TTTCCTGGAG GGACCAAGCT 
GTGCTGCGGC AGGACGGGGT GGTGGTGACC ATCAACAAGA AGAGGAACCT GGTGGTGTCT 
GTGGACGACG GTGGCACCTT TGAGGTTGTT TTGCACCGAG TGTGGAAGGG GAGCTCGGTC 
CACCAGGACT TCCTGGGCTT CTATGTGCTG GACAGTCATC GGATGTCAGC CCGGACGCAC 
GGGCTGCTGG GGCAATTTTT CCACCCCATC GGTTTTGAAG TGTCTGACAT CCACCCAGGC 
TCTGACCCCA CAAAGCCAGA TGCCACGATG GTGGTGAGGA ACCGCCGGCT CACGGTCACC 
AGGGGTTTGC AAAAAGACTA CAGCAAGGAC CCGTGGCATG GGGCCGAGGT GTCCTGCTGG 
TTCATTCACA ACAATGGGGC TGGACTCATC GATGGTGCCT ACACTGATTA TATCGTCCCC 
GACATCTTCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ITIH1 ( NM_001166436.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001159908.1 Homo sapiens inter-alpha-trypsin inhibitor heavy chain 1 (ITIH1), transcript variant 4, mRNA.

Price & Availability↑

CloneID	OHu20775
Clone ID Related Accession (Same CDS sequence)	NM_001166435.2 , NM_001166436.2
Accession Version	NM_001166436.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1872bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-23
Organism	Homo sapiens(human)
Product	inter-alpha-trypsin inhibitor heavy chain H1 isoform c
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK303110.1, AC006254.10 and AA897466.1. On Oct 28, 2011 this sequence version replaced NM_001166436.1. Transcript Variant: This variant (4) differs in the 5' UTR and coding sequence compared to variant 1. The resulting isoform (c) has a shorter N-terminus and lacks a predicted signal peptide compared to isoform a. Both variants 3 and 4 encode isoform c. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK303110.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAACAAGA ACGTGGTTTT TGTGATTGAC ATCAGTGGCT CCATGAGAGG CCAGAAAGTG 
AAGCAGACCA AGGAGGCACT CCTTAAAATT CTGGGGGACA TGCAGCCAGG GGACTACTTT 
GACCTGGTTC TTTTTGGGAC TCGAGTACAA TCGTGGAAGG GCTCGCTGGT GCAAGCATCT 
GAGGCCAACC TACAAGCAGC TCAAGACTTT GTGCGGGGCT TTTCCCTGGA TGAGGCCACA 
AACCTGAATG GAGGTTTGCT CCGGGGAATT GAGATCTTGA ACCAAGTTCA GGAAAGCCTC 
CCAGAACTCA GCAACCATGC CTCAATACTC ATCATGTTGA CAGATGGCGA TCCCACAGAG 
GGGGTGACGG ACCGTTCCCA AATCCTCAAG AACGTCCGCA ACGCCATCCG GGGCAGGTTC 
CCGCTCTACA ACCTGGGTTT CGGCCACAAT GTGGACTTTA ACTTTCTGGA GGTCATGTCC 
ATGGAGAACA ACGGACGGGC CCAGAGAATC TACGAGGACC ATGATGCCAC CCAGCAGCTG 
CAGGGTTTCT ACAGCCAGGT AGCCAAACCC CTGCTGGTGG ATGTGGATTT GCAGTACCCC 
CAGGATGCTG TCTTGGCCCT GACCCAGAAC CACCATAAAC AGTACTACGA AGGCTCAGAG 
ATTGTGGTGG CCGGGCGCAT TGCTGACAAC AAACAGAGCA GCTTCAAGGC TGATGTGCAG 
GCCCATGGGG AGGGACAAGA ATTCAGTATA ACCTGCCTAG TGGATGAGGA GGAGATGAAG 
AAACTGCTCC GAGAGCGTGG CCACATGCTG GAGAACCACG TCGAGCGCCT CTGGGCCTAC 
CTCACCATCC AGGAGCTGCT GGCCAAGCGG ATGAAGGTGG ACAGGGAGGA GAGGGCCAAC 
CTGTCATCCC AGGCCCTGCA GATGTCGCTG GACTATGGGT TTGTGACCCC ACTGACCTCC 
ATGAGCATCA GGGGCATGGC GGACCAGGAC GGCCTGAAGC CCACCATCGA CAAGCCCTCA 
GAGGATTCTC CGCCTTTGGA GATGCTGGGA CCCAGAAGGA CGTTCGTGCT GTCAGCCTTG 
CAGCCTTCTC CTACTCATTC CAGCTCCAAT ACCCAGCGGC TGCCAGACCG AGTGACCGGC 
GTGGACACAG ACCCTCACTT CATCATCCAC GTGCCCCAGA AAGAGGACAC CCTGTGCTTC 
AACATCAATG AGGAGCCTGG TGTTATCCTG AGCCTGGTAC AGGACCCCAA CACAGGCTTC 
TCAGTGAATG GACAGCTCAT TGGCAACAAG GCCAGGAGCC CTGGGCAGCA TGACGGCACG 
TACTTCGGGC GGCTGGGAAT CGCAAACCCT GCCACGGACT TTCAGTTGGA AGTGACTCCT 
CAGAACATTA CGCTGAACCC CGGCTTTGGT GGGCCTGTGT TTTCCTGGAG GGACCAAGCT 
GTGCTGCGGC AGGACGGGGT GGTGGTGACC ATCAACAAGA AGAGGAACCT GGTGGTGTCT 
GTGGACGACG GTGGCACCTT TGAGGTTGTT TTGCACCGAG TGTGGAAGGG GAGCTCGGTC 
CACCAGGACT TCCTGGGCTT CTATGTGCTG GACAGTCATC GGATGTCAGC CCGGACGCAC 
GGGCTGCTGG GGCAATTTTT CCACCCCATC GGTTTTGAAG TGTCTGACAT CCACCCAGGC 
TCTGACCCCA CAAAGCCAGA TGCCACGATG GTGGTGAGGA ACCGCCGGCT CACGGTCACC 
AGGGGTTTGC AAAAAGACTA CAGCAAGGAC CCGTGGCATG GGGCCGAGGT GTCCTGCTGG 
TTCATTCACA ACAATGGGGC TGGACTCATC GATGGTGCCT ACACTGATTA TATCGTCCCC 
GACATCTTCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001159908.1
CDS	351..2222
Translation	MNKNVVFVIDISGSMRGQKVKQTKEALLKILGDMQPGDYFDLVLFGTRVQSWKGSLVQASEANLQAAQDFVRGFSLDEATNLNGGLLRGIEILNQVQESLPELSNHASILIMLTDGDPTEGVTDRSQILKNVRNAIRGRFPLYNLGFGHNVDFNFLEVMSMENNGRAQRIYEDHDATQQLQGFYSQVAKPLLVDVDLQYPQDAVLALTQNHHKQYYEGSEIVVAGRIADNKQSSFKADVQAHGEGQEFSITCLVDEEEMKKLLRERGHMLENHVERLWAYLTIQELLAKRMKVDREERANLSSQALQMSLDYGFVTPLTSMSIRGMADQDGLKPTIDKPSEDSPPLEMLGPRRTFVLSALQPSPTHSSSNTQRLPDRVTGVDTDPHFIIHVPQKEDTLCFNINEEPGVILSLVQDPNTGFSVNGQLIGNKARSPGQHDGTYFGRLGIANPATDFQLEVTPQNITLNPGFGGPVFSWRDQAVLRQDGVVVTINKKRNLVVSVDDGGTFEVVLHRVWKGSSVHQDFLGFYVLDSHRMSARTHGLLGQFFHPIGFEVSDIHPGSDPTKPDATMVVRNRRLTVTRGLQKDYSKDPWHGAEVSCWFIHNNGAGLIDGAYTDYIVPDIF

Target ORF information:

RefSeq Version	NM_001166436.2
Organism	Homo sapiens(human)
Definition	Homo sapiens inter-alpha-trypsin inhibitor heavy chain 1 (ITIH1), transcript variant 4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001166436.2

ORF Insert Sequence:

ATGAACAAGA ACGTGGTTTT TGTGATTGAC ATCAGTGGCT CCATGAGAGG CCAGAAAGTG 
AAGCAGACCA AGGAGGCACT CCTTAAAATT CTGGGGGACA TGCAGCCAGG GGACTACTTT 
GACCTGGTTC TTTTTGGGAC TCGAGTACAA TCGTGGAAGG GCTCGCTGGT GCAAGCATCT 
GAGGCCAACC TACAAGCAGC TCAAGACTTT GTGCGGGGCT TTTCCCTGGA TGAGGCCACA 
AACCTGAATG GAGGTTTGCT CCGGGGAATT GAGATCTTGA ACCAAGTTCA GGAAAGCCTC 
CCAGAACTCA GCAACCATGC CTCAATACTC ATCATGTTGA CAGATGGCGA TCCCACAGAG 
GGGGTGACGG ACCGTTCCCA AATCCTCAAG AACGTCCGCA ACGCCATCCG GGGCAGGTTC 
CCGCTCTACA ACCTGGGTTT CGGCCACAAT GTGGACTTTA ACTTTCTGGA GGTCATGTCC 
ATGGAGAACA ACGGACGGGC CCAGAGAATC TACGAGGACC ATGATGCCAC CCAGCAGCTG 
CAGGGTTTCT ACAGCCAGGT AGCCAAACCC CTGCTGGTGG ATGTGGATTT GCAGTACCCC 
CAGGATGCTG TCTTGGCCCT GACCCAGAAC CACCATAAAC AGTACTACGA AGGCTCAGAG 
ATTGTGGTGG CCGGGCGCAT TGCTGACAAC AAACAGAGCA GCTTCAAGGC TGATGTGCAG 
GCCCATGGGG AGGGACAAGA ATTCAGTATA ACCTGCCTAG TGGATGAGGA GGAGATGAAG 
AAACTGCTCC GAGAGCGTGG CCACATGCTG GAGAACCACG TCGAGCGCCT CTGGGCCTAC 
CTCACCATCC AGGAGCTGCT GGCCAAGCGG ATGAAGGTGG ACAGGGAGGA GAGGGCCAAC 
CTGTCATCCC AGGCCCTGCA GATGTCGCTG GACTATGGGT TTGTGACCCC ACTGACCTCC 
ATGAGCATCA GGGGCATGGC GGACCAGGAC GGCCTGAAGC CCACCATCGA CAAGCCCTCA 
GAGGATTCTC CGCCTTTGGA GATGCTGGGA CCCAGAAGGA CGTTCGTGCT GTCAGCCTTG 
CAGCCTTCTC CTACTCATTC CAGCTCCAAT ACCCAGCGGC TGCCAGACCG AGTGACCGGC 
GTGGACACAG ACCCTCACTT CATCATCCAC GTGCCCCAGA AAGAGGACAC CCTGTGCTTC 
AACATCAATG AGGAGCCTGG TGTTATCCTG AGCCTGGTAC AGGACCCCAA CACAGGCTTC 
TCAGTGAATG GACAGCTCAT TGGCAACAAG GCCAGGAGCC CTGGGCAGCA TGACGGCACG 
TACTTCGGGC GGCTGGGAAT CGCAAACCCT GCCACGGACT TTCAGTTGGA AGTGACTCCT 
CAGAACATTA CGCTGAACCC CGGCTTTGGT GGGCCTGTGT TTTCCTGGAG GGACCAAGCT 
GTGCTGCGGC AGGACGGGGT GGTGGTGACC ATCAACAAGA AGAGGAACCT GGTGGTGTCT 
GTGGACGACG GTGGCACCTT TGAGGTTGTT TTGCACCGAG TGTGGAAGGG GAGCTCGGTC 
CACCAGGACT TCCTGGGCTT CTATGTGCTG GACAGTCATC GGATGTCAGC CCGGACGCAC 
GGGCTGCTGG GGCAATTTTT CCACCCCATC GGTTTTGAAG TGTCTGACAT CCACCCAGGC 
TCTGACCCCA CAAAGCCAGA TGCCACGATG GTGGTGAGGA ACCGCCGGCT CACGGTCACC 
AGGGGTTTGC AAAAAGACTA CAGCAAGGAC CCGTGGCATG GGGCCGAGGT GTCCTGCTGG 
TTCATTCACA ACAATGGGGC TGGACTCATC GATGGTGCCT ACACTGATTA TATCGTCCCC 
GACATCTTCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ITIH1 ( NM_002215.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_002206.2 Homo sapiens inter-alpha-trypsin inhibitor heavy chain 1 (ITIH1), transcript variant 1, mRNA.

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CloneID	OHu20213
Clone ID Related Accession (Same CDS sequence)	NM_002215.3 , NM_002215.4
Accession Version	NM_002215.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2736bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Homo sapiens(human)
Product	inter-alpha-trypsin inhibitor heavy chain H1 isoform a preproprotein
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BX496392.1, BC069464.1 and AA897466.1. This sequence is a reference standard in the RefSeqGene project. On Oct 28, 2011 this sequence version replaced NM_002215.2. Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (a). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: X63652.1, AK292750.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2145122, SAMEA2155590 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGACGGTG CCATGGGGCC TCGGGGGCTG CTGTTGTGCA TGTACCTGGT ATCTCTCCTC 
ATCCTGCAGG CCATGCCTGC CCTGGGCTCG GCTACAGGCA GGTCCAAGAG CAGCGAGAAG 
CGACAGGCTG TGGACACCGC TGTCGATGGC GTGTTCATCC GGAGTTTGAA AGTCAACTGC 
AAAGTCACCT CTCGCTTCGC CCACTATGTT GTCACCAGCC AAGTGGTCAA CACTGCCAAT 
GAAGCCAGGG AAGTGGCCTT CGACCTGGAA ATCCCCAAGA CAGCATTCAT CAGTGACTTT 
GCCGTTACAG CAGATGGAAA CGCATTTATC GGAGACATAA AGGACAAGGT GACTGCATGG 
AAGCAGTACC GGAAAGCAGC TATCTCAGGA GAGAATGCCG GCCTTGTCAG GGCCTCGGGG 
AGAACTATGG AGCAATTCAC CATCCACCTC ACCGTCAATC CCCAGAGCAA GGTCACGTTT 
CAGCTGACTT ATGAGGAAGT GCTGAAGAGA AACCATATGC AGTATGAAAT TGTCATCAAA 
GTCAAGCCCA AGCAGCTGGT GCATCATTTT GAGATTGATG TGGACATCTT CGAGCCCCAG 
GGGATCAGCA AGCTGGATGC CCAGGCCTCT TTCCTGCCGA AGGAACTGGC AGCCCAAACT 
ATCAAGAAGT CCTTCTCAGG AAAAAAGGGT CATGTGCTGT TCCGTCCCAC CGTGAGCCAG 
CAGCAGTCCT GCCCCACATG CTCTACATCC TTACTGAACG GGCACTTCAA GGTGACCTAC 
GATGTCAGTC GAGACAAGAT CTGCGACCTC CTGGTGGCCA ATAACCACTT TGCCCACTTC 
TTTGCCCCCC AAAACCTGAC AAACATGAAC AAGAACGTGG TTTTTGTGAT TGACATCAGT 
GGCTCCATGA GAGGCCAGAA AGTGAAGCAG ACCAAGGAGG CACTCCTTAA AATTCTGGGG 
GACATGCAGC CAGGGGACTA CTTTGACCTG GTTCTTTTTG GGACTCGAGT ACAATCGTGG 
AAGGGCTCGC TGGTGCAAGC ATCTGAGGCC AACCTACAAG CAGCTCAAGA CTTTGTGCGG 
GGCTTTTCCC TGGATGAGGC CACAAACCTG AATGGAGGTT TGCTCCGGGG AATTGAGATC 
TTGAACCAAG TTCAGGAAAG CCTCCCAGAA CTCAGCAACC ATGCCTCAAT ACTCATCATG 
TTGACAGATG GCGATCCCAC AGAGGGGGTG ACGGACCGTT CCCAAATCCT CAAGAACGTC 
CGCAACGCCA TCCGGGGCAG GTTCCCGCTC TACAACCTGG GTTTCGGCCA CAATGTGGAC 
TTTAACTTTC TGGAGGTCAT GTCCATGGAG AACAACGGAC GGGCCCAGAG AATCTACGAG 
GACCATGATG CCACCCAGCA GCTGCAGGGT TTCTACAGCC AGGTAGCCAA ACCCCTGCTG 
GTGGATGTGG ATTTGCAGTA CCCCCAGGAT GCTGTCTTGG CCCTGACCCA GAACCACCAT 
AAACAGTACT ACGAAGGCTC AGAGATTGTG GTGGCCGGGC GCATTGCTGA CAACAAACAG 
AGCAGCTTCA AGGCTGATGT GCAGGCCCAT GGGGAGGGAC AAGAATTCAG TATAACCTGC 
CTAGTGGATG AGGAGGAGAT GAAGAAACTG CTCCGAGAGC GTGGCCACAT GCTGGAGAAC 
CACGTCGAGC GCCTCTGGGC CTACCTCACC ATCCAGGAGC TGCTGGCCAA GCGGATGAAG 
GTGGACAGGG AGGAGAGGGC CAACCTGTCA TCCCAGGCCC TGCAGATGTC GCTGGACTAT 
GGGTTTGTGA CCCCACTGAC CTCCATGAGC ATCAGGGGCA TGGCGGACCA GGACGGCCTG 
AAGCCCACCA TCGACAAGCC CTCAGAGGAT TCTCCGCCTT TGGAGATGCT GGGACCCAGA 
AGGACGTTCG TGCTGTCAGC CTTGCAGCCT TCTCCTACTC ATTCCAGCTC CAATACCCAG 
CGGCTGCCAG ACCGAGTGAC CGGCGTGGAC ACAGACCCTC ACTTCATCAT CCACGTGCCC 
CAGAAAGAGG ACACCCTGTG CTTCAACATC AATGAGGAGC CTGGTGTTAT CCTGAGCCTG 
GTACAGGACC CCAACACAGG CTTCTCAGTG AATGGACAGC TCATTGGCAA CAAGGCCAGG 
AGCCCTGGGC AGCATGACGG CACGTACTTC GGGCGGCTGG GAATCGCAAA CCCTGCCACG 
GACTTTCAGT TGGAAGTGAC TCCTCAGAAC ATTACGCTGA ACCCCGGCTT TGGTGGGCCT 
GTGTTTTCCT GGAGGGACCA AGCTGTGCTG CGGCAGGACG GGGTGGTGGT GACCATCAAC 
AAGAAGAGGA ACCTGGTGGT GTCTGTGGAC GACGGTGGCA CCTTTGAGGT TGTTTTGCAC 
CGAGTGTGGA AGGGGAGCTC GGTCCACCAG GACTTCCTGG GCTTCTATGT GCTGGACAGT 
CATCGGATGT CAGCCCGGAC GCACGGGCTG CTGGGGCAAT TTTTCCACCC CATCGGTTTT 
GAAGTGTCTG ACATCCACCC AGGCTCTGAC CCCACAAAGC CAGATGCCAC GATGGTGGTG 
AGGAACCGCC GGCTCACGGT CACCAGGGGT TTGCAAAAAG ACTACAGCAA GGACCCGTGG 
CATGGGGCCG AGGTGTCCTG CTGGTTCATT CACAACAATG GGGCTGGACT CATCGATGGT 
GCCTACACTG ATTATATCGT CCCCGACATC TTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_002206.2
CDS	31..2766
Translation	MDGAMGPRGLLLCMYLVSLLILQAMPALGSATGRSKSSEKRQAVDTAVDGVFIRSLKVNCKVTSRFAHYVVTSQVVNTANEAREVAFDLEIPKTAFISDFAVTADGNAFIGDIKDKVTAWKQYRKAAISGENAGLVRASGRTMEQFTIHLTVNPQSKVTFQLTYEEVLKRNHMQYEIVIKVKPKQLVHHFEIDVDIFEPQGISKLDAQASFLPKELAAQTIKKSFSGKKGHVLFRPTVSQQQSCPTCSTSLLNGHFKVTYDVSRDKICDLLVANNHFAHFFAPQNLTNMNKNVVFVIDISGSMRGQKVKQTKEALLKILGDMQPGDYFDLVLFGTRVQSWKGSLVQASEANLQAAQDFVRGFSLDEATNLNGGLLRGIEILNQVQESLPELSNHASILIMLTDGDPTEGVTDRSQILKNVRNAIRGRFPLYNLGFGHNVDFNFLEVMSMENNGRAQRIYEDHDATQQLQGFYSQVAKPLLVDVDLQYPQDAVLALTQNHHKQYYEGSEIVVAGRIADNKQSSFKADVQAHGEGQEFSITCLVDEEEMKKLLRERGHMLENHVERLWAYLTIQELLAKRMKVDREERANLSSQALQMSLDYGFVTPLTSMSIRGMADQDGLKPTIDKPSEDSPPLEMLGPRRTFVLSALQPSPTHSSSNTQRLPDRVTGVDTDPHFIIHVPQKEDTLCFNINEEPGVILSLVQDPNTGFSVNGQLIGNKARSPGQHDGTYFGRLGIANPATDFQLEVTPQNITLNPGFGGPVFSWRDQAVLRQDGVVVTINKKRNLVVSVDDGGTFEVVLHRVWKGSSVHQDFLGFYVLDSHRMSARTHGLLGQFFHPIGFEVSDIHPGSDPTKPDATMVVRNRRLTVTRGLQKDYSKDPWHGAEVSCWFIHNNGAGLIDGAYTDYIVPDIF

Target ORF information:

RefSeq Version	NM_002215.3
Organism	Homo sapiens(human)
Definition	Homo sapiens inter-alpha-trypsin inhibitor heavy chain 1 (ITIH1), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_002215.3

ORF Insert Sequence:

ATGGACGGTG CCATGGGGCC TCGGGGGCTG CTGTTGTGCA TGTACCTGGT ATCTCTCCTC 
ATCCTGCAGG CCATGCCTGC CCTGGGCTCG GCTACAGGCA GGTCCAAGAG CAGCGAGAAG 
CGACAGGCTG TGGACACCGC TGTCGATGGC GTGTTCATCC GGAGTTTGAA AGTCAACTGC 
AAAGTCACCT CTCGCTTCGC CCACTATGTT GTCACCAGCC AAGTGGTCAA CACTGCCAAT 
GAAGCCAGGG AAGTGGCCTT CGACCTGGAA ATCCCCAAGA CAGCATTCAT CAGTGACTTT 
GCCGTTACAG CAGATGGAAA CGCATTTATC GGAGACATAA AGGACAAGGT GACTGCATGG 
AAGCAGTACC GGAAAGCAGC TATCTCAGGA GAGAATGCCG GCCTTGTCAG GGCCTCGGGG 
AGAACTATGG AGCAATTCAC CATCCACCTC ACCGTCAATC CCCAGAGCAA GGTCACGTTT 
CAGCTGACTT ATGAGGAAGT GCTGAAGAGA AACCATATGC AGTATGAAAT TGTCATCAAA 
GTCAAGCCCA AGCAGCTGGT GCATCATTTT GAGATTGATG TGGACATCTT CGAGCCCCAG 
GGGATCAGCA AGCTGGATGC CCAGGCCTCT TTCCTGCCGA AGGAACTGGC AGCCCAAACT 
ATCAAGAAGT CCTTCTCAGG AAAAAAGGGT CATGTGCTGT TCCGTCCCAC CGTGAGCCAG 
CAGCAGTCCT GCCCCACATG CTCTACATCC TTACTGAACG GGCACTTCAA GGTGACCTAC 
GATGTCAGTC GAGACAAGAT CTGCGACCTC CTGGTGGCCA ATAACCACTT TGCCCACTTC 
TTTGCCCCCC AAAACCTGAC AAACATGAAC AAGAACGTGG TTTTTGTGAT TGACATCAGT 
GGCTCCATGA GAGGCCAGAA AGTGAAGCAG ACCAAGGAGG CACTCCTTAA AATTCTGGGG 
GACATGCAGC CAGGGGACTA CTTTGACCTG GTTCTTTTTG GGACTCGAGT ACAATCGTGG 
AAGGGCTCGC TGGTGCAAGC ATCTGAGGCC AACCTACAAG CAGCTCAAGA CTTTGTGCGG 
GGCTTTTCCC TGGATGAGGC CACAAACCTG AATGGAGGTT TGCTCCGGGG AATTGAGATC 
TTGAACCAAG TTCAGGAAAG CCTCCCAGAA CTCAGCAACC ATGCCTCAAT ACTCATCATG 
TTGACAGATG GCGATCCCAC AGAGGGGGTG ACGGACCGTT CCCAAATCCT CAAGAACGTC 
CGCAACGCCA TCCGGGGCAG GTTCCCGCTC TACAACCTGG GTTTCGGCCA CAATGTGGAC 
TTTAACTTTC TGGAGGTCAT GTCCATGGAG AACAACGGAC GGGCCCAGAG AATCTACGAG 
GACCATGATG CCACCCAGCA GCTGCAGGGT TTCTACAGCC AGGTAGCCAA ACCCCTGCTG 
GTGGATGTGG ATTTGCAGTA CCCCCAGGAT GCTGTCTTGG CCCTGACCCA GAACCACCAT 
AAACAGTACT ACGAAGGCTC AGAGATTGTG GTGGCCGGGC GCATTGCTGA CAACAAACAG 
AGCAGCTTCA AGGCTGATGT GCAGGCCCAT GGGGAGGGAC AAGAATTCAG TATAACCTGC 
CTAGTGGATG AGGAGGAGAT GAAGAAACTG CTCCGAGAGC GTGGCCACAT GCTGGAGAAC 
CACGTCGAGC GCCTCTGGGC CTACCTCACC ATCCAGGAGC TGCTGGCCAA GCGGATGAAG 
GTGGACAGGG AGGAGAGGGC CAACCTGTCA TCCCAGGCCC TGCAGATGTC GCTGGACTAT 
GGGTTTGTGA CCCCACTGAC CTCCATGAGC ATCAGGGGCA TGGCGGACCA GGACGGCCTG 
AAGCCCACCA TCGACAAGCC CTCAGAGGAT TCTCCGCCTT TGGAGATGCT GGGACCCAGA 
AGGACGTTCG TGCTGTCAGC CTTGCAGCCT TCTCCTACTC ATTCCAGCTC CAATACCCAG 
CGGCTGCCAG ACCGAGTGAC CGGCGTGGAC ACAGACCCTC ACTTCATCAT CCACGTGCCC 
CAGAAAGAGG ACACCCTGTG CTTCAACATC AATGAGGAGC CTGGTGTTAT CCTGAGCCTG 
GTACAGGACC CCAACACAGG CTTCTCAGTG AATGGACAGC TCATTGGCAA CAAGGCCAGG 
AGCCCTGGGC AGCATGACGG CACGTACTTC GGGCGGCTGG GAATCGCAAA CCCTGCCACG 
GACTTTCAGT TGGAAGTGAC TCCTCAGAAC ATTACGCTGA ACCCCGGCTT TGGTGGGCCT 
GTGTTTTCCT GGAGGGACCA AGCTGTGCTG CGGCAGGACG GGGTGGTGGT GACCATCAAC 
AAGAAGAGGA ACCTGGTGGT GTCTGTGGAC GACGGTGGCA CCTTTGAGGT TGTTTTGCAC 
CGAGTGTGGA AGGGGAGCTC GGTCCACCAG GACTTCCTGG GCTTCTATGT GCTGGACAGT 
CATCGGATGT CAGCCCGGAC GCACGGGCTG CTGGGGCAAT TTTTCCACCC CATCGGTTTT 
GAAGTGTCTG ACATCCACCC AGGCTCTGAC CCCACAAAGC CAGATGCCAC GATGGTGGTG 
AGGAACCGCC GGCTCACGGT CACCAGGGGT TTGCAAAAAG ACTACAGCAA GGACCCGTGG 
CATGGGGCCG AGGTGTCCTG CTGGTTCATT CACAACAATG GGGCTGGACT CATCGATGGT 
GCCTACACTG ATTATATCGT CCCCGACATC TTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ITIH1 ( NM_002215.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_002206.2 Homo sapiens inter-alpha-trypsin inhibitor heavy chain 1 (ITIH1), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu20213
Clone ID Related Accession (Same CDS sequence)	NM_002215.3 , NM_002215.4
Accession Version	NM_002215.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2736bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-26
Organism	Homo sapiens(human)
Product	inter-alpha-trypsin inhibitor heavy chain H1 isoform a preproprotein
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC069464.1 and AA897466.1. This sequence is a reference standard in the RefSeqGene project. On Nov 23, 2018 this sequence version replaced NM_002215.3. Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (a). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: X63652.1, SRR5189664.80686.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2145122, SAMEA2155590 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000273283.7/ ENSP00000273283.2 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGACGGTG CCATGGGGCC TCGGGGGCTG CTGTTGTGCA TGTACCTGGT ATCTCTCCTC 
ATCCTGCAGG CCATGCCTGC CCTGGGCTCG GCTACAGGCA GGTCCAAGAG CAGCGAGAAG 
CGACAGGCTG TGGACACCGC TGTCGATGGC GTGTTCATCC GGAGTTTGAA AGTCAACTGC 
AAAGTCACCT CTCGCTTCGC CCACTATGTT GTCACCAGCC AAGTGGTCAA CACTGCCAAT 
GAAGCCAGGG AAGTGGCCTT CGACCTGGAA ATCCCCAAGA CAGCATTCAT CAGTGACTTT 
GCCGTTACAG CAGATGGAAA CGCATTTATC GGAGACATAA AGGACAAGGT GACTGCATGG 
AAGCAGTACC GGAAAGCAGC TATCTCAGGA GAGAATGCCG GCCTTGTCAG GGCCTCGGGG 
AGAACTATGG AGCAATTCAC CATCCACCTC ACCGTCAATC CCCAGAGCAA GGTCACGTTT 
CAGCTGACTT ATGAGGAAGT GCTGAAGAGA AACCATATGC AGTATGAAAT TGTCATCAAA 
GTCAAGCCCA AGCAGCTGGT GCATCATTTT GAGATTGATG TGGACATCTT CGAGCCCCAG 
GGGATCAGCA AGCTGGATGC CCAGGCCTCT TTCCTGCCGA AGGAACTGGC AGCCCAAACT 
ATCAAGAAGT CCTTCTCAGG AAAAAAGGGT CATGTGCTGT TCCGTCCCAC CGTGAGCCAG 
CAGCAGTCCT GCCCCACATG CTCTACATCC TTACTGAACG GGCACTTCAA GGTGACCTAC 
GATGTCAGTC GAGACAAGAT CTGCGACCTC CTGGTGGCCA ATAACCACTT TGCCCACTTC 
TTTGCCCCCC AAAACCTGAC AAACATGAAC AAGAACGTGG TTTTTGTGAT TGACATCAGT 
GGCTCCATGA GAGGCCAGAA AGTGAAGCAG ACCAAGGAGG CACTCCTTAA AATTCTGGGG 
GACATGCAGC CAGGGGACTA CTTTGACCTG GTTCTTTTTG GGACTCGAGT ACAATCGTGG 
AAGGGCTCGC TGGTGCAAGC ATCTGAGGCC AACCTACAAG CAGCTCAAGA CTTTGTGCGG 
GGCTTTTCCC TGGATGAGGC CACAAACCTG AATGGAGGTT TGCTCCGGGG AATTGAGATC 
TTGAACCAAG TTCAGGAAAG CCTCCCAGAA CTCAGCAACC ATGCCTCAAT ACTCATCATG 
TTGACAGATG GCGATCCCAC AGAGGGGGTG ACGGACCGTT CCCAAATCCT CAAGAACGTC 
CGCAACGCCA TCCGGGGCAG GTTCCCGCTC TACAACCTGG GTTTCGGCCA CAATGTGGAC 
TTTAACTTTC TGGAGGTCAT GTCCATGGAG AACAACGGAC GGGCCCAGAG AATCTACGAG 
GACCATGATG CCACCCAGCA GCTGCAGGGT TTCTACAGCC AGGTAGCCAA ACCCCTGCTG 
GTGGATGTGG ATTTGCAGTA CCCCCAGGAT GCTGTCTTGG CCCTGACCCA GAACCACCAT 
AAACAGTACT ACGAAGGCTC AGAGATTGTG GTGGCCGGGC GCATTGCTGA CAACAAACAG 
AGCAGCTTCA AGGCTGATGT GCAGGCCCAT GGGGAGGGAC AAGAATTCAG TATAACCTGC 
CTAGTGGATG AGGAGGAGAT GAAGAAACTG CTCCGAGAGC GTGGCCACAT GCTGGAGAAC 
CACGTCGAGC GCCTCTGGGC CTACCTCACC ATCCAGGAGC TGCTGGCCAA GCGGATGAAG 
GTGGACAGGG AGGAGAGGGC CAACCTGTCA TCCCAGGCCC TGCAGATGTC GCTGGACTAT 
GGGTTTGTGA CCCCACTGAC CTCCATGAGC ATCAGGGGCA TGGCGGACCA GGACGGCCTG 
AAGCCCACCA TCGACAAGCC CTCAGAGGAT TCTCCGCCTT TGGAGATGCT GGGACCCAGA 
AGGACGTTCG TGCTGTCAGC CTTGCAGCCT TCTCCTACTC ATTCCAGCTC CAATACCCAG 
CGGCTGCCAG ACCGAGTGAC CGGCGTGGAC ACAGACCCTC ACTTCATCAT CCACGTGCCC 
CAGAAAGAGG ACACCCTGTG CTTCAACATC AATGAGGAGC CTGGTGTTAT CCTGAGCCTG 
GTACAGGACC CCAACACAGG CTTCTCAGTG AATGGACAGC TCATTGGCAA CAAGGCCAGG 
AGCCCTGGGC AGCATGACGG CACGTACTTC GGGCGGCTGG GAATCGCAAA CCCTGCCACG 
GACTTTCAGT TGGAAGTGAC TCCTCAGAAC ATTACGCTGA ACCCCGGCTT TGGTGGGCCT 
GTGTTTTCCT GGAGGGACCA AGCTGTGCTG CGGCAGGACG GGGTGGTGGT GACCATCAAC 
AAGAAGAGGA ACCTGGTGGT GTCTGTGGAC GACGGTGGCA CCTTTGAGGT TGTTTTGCAC 
CGAGTGTGGA AGGGGAGCTC GGTCCACCAG GACTTCCTGG GCTTCTATGT GCTGGACAGT 
CATCGGATGT CAGCCCGGAC GCACGGGCTG CTGGGGCAAT TTTTCCACCC CATCGGTTTT 
GAAGTGTCTG ACATCCACCC AGGCTCTGAC CCCACAAAGC CAGATGCCAC GATGGTGGTG 
AGGAACCGCC GGCTCACGGT CACCAGGGGT TTGCAAAAAG ACTACAGCAA GGACCCGTGG 
CATGGGGCCG AGGTGTCCTG CTGGTTCATT CACAACAATG GGGCTGGACT CATCGATGGT 
GCCTACACTG ATTATATCGT CCCCGACATC TTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_002206.2
CDS	18..2753
Translation	MDGAMGPRGLLLCMYLVSLLILQAMPALGSATGRSKSSEKRQAVDTAVDGVFIRSLKVNCKVTSRFAHYVVTSQVVNTANEAREVAFDLEIPKTAFISDFAVTADGNAFIGDIKDKVTAWKQYRKAAISGENAGLVRASGRTMEQFTIHLTVNPQSKVTFQLTYEEVLKRNHMQYEIVIKVKPKQLVHHFEIDVDIFEPQGISKLDAQASFLPKELAAQTIKKSFSGKKGHVLFRPTVSQQQSCPTCSTSLLNGHFKVTYDVSRDKICDLLVANNHFAHFFAPQNLTNMNKNVVFVIDISGSMRGQKVKQTKEALLKILGDMQPGDYFDLVLFGTRVQSWKGSLVQASEANLQAAQDFVRGFSLDEATNLNGGLLRGIEILNQVQESLPELSNHASILIMLTDGDPTEGVTDRSQILKNVRNAIRGRFPLYNLGFGHNVDFNFLEVMSMENNGRAQRIYEDHDATQQLQGFYSQVAKPLLVDVDLQYPQDAVLALTQNHHKQYYEGSEIVVAGRIADNKQSSFKADVQAHGEGQEFSITCLVDEEEMKKLLRERGHMLENHVERLWAYLTIQELLAKRMKVDREERANLSSQALQMSLDYGFVTPLTSMSIRGMADQDGLKPTIDKPSEDSPPLEMLGPRRTFVLSALQPSPTHSSSNTQRLPDRVTGVDTDPHFIIHVPQKEDTLCFNINEEPGVILSLVQDPNTGFSVNGQLIGNKARSPGQHDGTYFGRLGIANPATDFQLEVTPQNITLNPGFGGPVFSWRDQAVLRQDGVVVTINKKRNLVVSVDDGGTFEVVLHRVWKGSSVHQDFLGFYVLDSHRMSARTHGLLGQFFHPIGFEVSDIHPGSDPTKPDATMVVRNRRLTVTRGLQKDYSKDPWHGAEVSCWFIHNNGAGLIDGAYTDYIVPDIF

Target ORF information:

RefSeq Version	NM_002215.4
Organism	Homo sapiens(human)
Definition	Homo sapiens inter-alpha-trypsin inhibitor heavy chain 1 (ITIH1), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_002215.4

ORF Insert Sequence:

ATGGACGGTG CCATGGGGCC TCGGGGGCTG CTGTTGTGCA TGTACCTGGT ATCTCTCCTC 
ATCCTGCAGG CCATGCCTGC CCTGGGCTCG GCTACAGGCA GGTCCAAGAG CAGCGAGAAG 
CGACAGGCTG TGGACACCGC TGTCGATGGC GTGTTCATCC GGAGTTTGAA AGTCAACTGC 
AAAGTCACCT CTCGCTTCGC CCACTATGTT GTCACCAGCC AAGTGGTCAA CACTGCCAAT 
GAAGCCAGGG AAGTGGCCTT CGACCTGGAA ATCCCCAAGA CAGCATTCAT CAGTGACTTT 
GCCGTTACAG CAGATGGAAA CGCATTTATC GGAGACATAA AGGACAAGGT GACTGCATGG 
AAGCAGTACC GGAAAGCAGC TATCTCAGGA GAGAATGCCG GCCTTGTCAG GGCCTCGGGG 
AGAACTATGG AGCAATTCAC CATCCACCTC ACCGTCAATC CCCAGAGCAA GGTCACGTTT 
CAGCTGACTT ATGAGGAAGT GCTGAAGAGA AACCATATGC AGTATGAAAT TGTCATCAAA 
GTCAAGCCCA AGCAGCTGGT GCATCATTTT GAGATTGATG TGGACATCTT CGAGCCCCAG 
GGGATCAGCA AGCTGGATGC CCAGGCCTCT TTCCTGCCGA AGGAACTGGC AGCCCAAACT 
ATCAAGAAGT CCTTCTCAGG AAAAAAGGGT CATGTGCTGT TCCGTCCCAC CGTGAGCCAG 
CAGCAGTCCT GCCCCACATG CTCTACATCC TTACTGAACG GGCACTTCAA GGTGACCTAC 
GATGTCAGTC GAGACAAGAT CTGCGACCTC CTGGTGGCCA ATAACCACTT TGCCCACTTC 
TTTGCCCCCC AAAACCTGAC AAACATGAAC AAGAACGTGG TTTTTGTGAT TGACATCAGT 
GGCTCCATGA GAGGCCAGAA AGTGAAGCAG ACCAAGGAGG CACTCCTTAA AATTCTGGGG 
GACATGCAGC CAGGGGACTA CTTTGACCTG GTTCTTTTTG GGACTCGAGT ACAATCGTGG 
AAGGGCTCGC TGGTGCAAGC ATCTGAGGCC AACCTACAAG CAGCTCAAGA CTTTGTGCGG 
GGCTTTTCCC TGGATGAGGC CACAAACCTG AATGGAGGTT TGCTCCGGGG AATTGAGATC 
TTGAACCAAG TTCAGGAAAG CCTCCCAGAA CTCAGCAACC ATGCCTCAAT ACTCATCATG 
TTGACAGATG GCGATCCCAC AGAGGGGGTG ACGGACCGTT CCCAAATCCT CAAGAACGTC 
CGCAACGCCA TCCGGGGCAG GTTCCCGCTC TACAACCTGG GTTTCGGCCA CAATGTGGAC 
TTTAACTTTC TGGAGGTCAT GTCCATGGAG AACAACGGAC GGGCCCAGAG AATCTACGAG 
GACCATGATG CCACCCAGCA GCTGCAGGGT TTCTACAGCC AGGTAGCCAA ACCCCTGCTG 
GTGGATGTGG ATTTGCAGTA CCCCCAGGAT GCTGTCTTGG CCCTGACCCA GAACCACCAT 
AAACAGTACT ACGAAGGCTC AGAGATTGTG GTGGCCGGGC GCATTGCTGA CAACAAACAG 
AGCAGCTTCA AGGCTGATGT GCAGGCCCAT GGGGAGGGAC AAGAATTCAG TATAACCTGC 
CTAGTGGATG AGGAGGAGAT GAAGAAACTG CTCCGAGAGC GTGGCCACAT GCTGGAGAAC 
CACGTCGAGC GCCTCTGGGC CTACCTCACC ATCCAGGAGC TGCTGGCCAA GCGGATGAAG 
GTGGACAGGG AGGAGAGGGC CAACCTGTCA TCCCAGGCCC TGCAGATGTC GCTGGACTAT 
GGGTTTGTGA CCCCACTGAC CTCCATGAGC ATCAGGGGCA TGGCGGACCA GGACGGCCTG 
AAGCCCACCA TCGACAAGCC CTCAGAGGAT TCTCCGCCTT TGGAGATGCT GGGACCCAGA 
AGGACGTTCG TGCTGTCAGC CTTGCAGCCT TCTCCTACTC ATTCCAGCTC CAATACCCAG 
CGGCTGCCAG ACCGAGTGAC CGGCGTGGAC ACAGACCCTC ACTTCATCAT CCACGTGCCC 
CAGAAAGAGG ACACCCTGTG CTTCAACATC AATGAGGAGC CTGGTGTTAT CCTGAGCCTG 
GTACAGGACC CCAACACAGG CTTCTCAGTG AATGGACAGC TCATTGGCAA CAAGGCCAGG 
AGCCCTGGGC AGCATGACGG CACGTACTTC GGGCGGCTGG GAATCGCAAA CCCTGCCACG 
GACTTTCAGT TGGAAGTGAC TCCTCAGAAC ATTACGCTGA ACCCCGGCTT TGGTGGGCCT 
GTGTTTTCCT GGAGGGACCA AGCTGTGCTG CGGCAGGACG GGGTGGTGGT GACCATCAAC 
AAGAAGAGGA ACCTGGTGGT GTCTGTGGAC GACGGTGGCA CCTTTGAGGT TGTTTTGCAC 
CGAGTGTGGA AGGGGAGCTC GGTCCACCAG GACTTCCTGG GCTTCTATGT GCTGGACAGT 
CATCGGATGT CAGCCCGGAC GCACGGGCTG CTGGGGCAAT TTTTCCACCC CATCGGTTTT 
GAAGTGTCTG ACATCCACCC AGGCTCTGAC CCCACAAAGC CAGATGCCAC GATGGTGGTG 
AGGAACCGCC GGCTCACGGT CACCAGGGGT TTGCAAAAAG ACTACAGCAA GGACCCGTGG 
CATGGGGCCG AGGTGTCCTG CTGGTTCATT CACAACAATG GGGCTGGACT CATCGATGGT 
GCCTACACTG ATTATATCGT CCCCGACATC TTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ITIH1 ( NM_001166434.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001159906.1 Homo sapiens inter-alpha-trypsin inhibitor heavy chain 1 (ITIH1), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu21901
Clone ID Related Accession (Same CDS sequence)	NM_001166434.2 , NM_001166434.3
Accession Version	NM_001166434.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2310bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-10-12
Organism	Homo sapiens(human)
Product	inter-alpha-trypsin inhibitor heavy chain H1 isoform b
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DB188130.1, AK298455.1, AC006254.10, M18192.1, AK292750.1 and AA897466.1. On Oct 28, 2011 this sequence version replaced NM_001166434.1. Transcript Variant: This variant (2) differs in the 5' UTR and coding sequence compared to variant 1. The resulting isoform (b) has a shorter N-terminus and lacks a predicted signal peptide compared to isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK298455.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2145122, SAMEA2155590 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGAGCAAT TCACCATCCA CCTCACCGTC AATCCCCAGA GCAAGGTCAC GTTTCAGCTG 
ACTTATGAGG AAGTGCTGAA GAGAAACCAT ATGCAGTATG AAATTGTCAT CAAAGTCAAG 
CCCAAGCAGC TGGTGCATCA TTTTGAGATT GATGTGGACA TCTTCGAGCC CCAGGGGATC 
AGCAAGCTGG ATGCCCAGGC CTCTTTCCTG CCGAAGGAAC TGGCAGCCCA AACTATCAAG 
AAGTCCTTCT CAGGAAAAAA GGGTCATGTG CTGTTCCGTC CCACCGTGAG CCAGCAGCAG 
TCCTGCCCCA CATGCTCTAC ATCCTTACTG AACGGGCACT TCAAGGTGAC CTACGATGTC 
AGTCGAGACA AGATCTGCGA CCTCCTGGTG GCCAATAACC ACTTTGCCCA CTTCTTTGCC 
CCCCAAAACC TGACAAACAT GAACAAGAAC GTGGTTTTTG TGATTGACAT CAGTGGCTCC 
ATGAGAGGCC AGAAAGTGAA GCAGACCAAG GAGGCACTCC TTAAAATTCT GGGGGACATG 
CAGCCAGGGG ACTACTTTGA CCTGGTTCTT TTTGGGACTC GAGTACAATC GTGGAAGGGC 
TCGCTGGTGC AAGCATCTGA GGCCAACCTA CAAGCAGCTC AAGACTTTGT GCGGGGCTTT 
TCCCTGGATG AGGCCACAAA CCTGAATGGA GGTTTGCTCC GGGGAATTGA GATCTTGAAC 
CAAGTTCAGG AAAGCCTCCC AGAACTCAGC AACCATGCCT CAATACTCAT CATGTTGACA 
GATGGCGATC CCACAGAGGG GGTGACGGAC CGTTCCCAAA TCCTCAAGAA CGTCCGCAAC 
GCCATCCGGG GCAGGTTCCC GCTCTACAAC CTGGGTTTCG GCCACAATGT GGACTTTAAC 
TTTCTGGAGG TCATGTCCAT GGAGAACAAC GGACGGGCCC AGAGAATCTA CGAGGACCAT 
GATGCCACCC AGCAGCTGCA GGGTTTCTAC AGCCAGGTAG CCAAACCCCT GCTGGTGGAT 
GTGGATTTGC AGTACCCCCA GGATGCTGTC TTGGCCCTGA CCCAGAACCA CCATAAACAG 
TACTACGAAG GCTCAGAGAT TGTGGTGGCC GGGCGCATTG CTGACAACAA ACAGAGCAGC 
TTCAAGGCTG ATGTGCAGGC CCATGGGGAG GGACAAGAAT TCAGTATAAC CTGCCTAGTG 
GATGAGGAGG AGATGAAGAA ACTGCTCCGA GAGCGTGGCC ACATGCTGGA GAACCACGTC 
GAGCGCCTCT GGGCCTACCT CACCATCCAG GAGCTGCTGG CCAAGCGGAT GAAGGTGGAC 
AGGGAGGAGA GGGCCAACCT GTCATCCCAG GCCCTGCAGA TGTCGCTGGA CTATGGGTTT 
GTGACCCCAC TGACCTCCAT GAGCATCAGG GGCATGGCGG ACCAGGACGG CCTGAAGCCC 
ACCATCGACA AGCCCTCAGA GGATTCTCCG CCTTTGGAGA TGCTGGGACC CAGAAGGACG 
TTCGTGCTGT CAGCCTTGCA GCCTTCTCCT ACTCATTCCA GCTCCAATAC CCAGCGGCTG 
CCAGACCGAG TGACCGGCGT GGACACAGAC CCTCACTTCA TCATCCACGT GCCCCAGAAA 
GAGGACACCC TGTGCTTCAA CATCAATGAG GAGCCTGGTG TTATCCTGAG CCTGGTACAG 
GACCCCAACA CAGGCTTCTC AGTGAATGGA CAGCTCATTG GCAACAAGGC CAGGAGCCCT 
GGGCAGCATG ACGGCACGTA CTTCGGGCGG CTGGGAATCG CAAACCCTGC CACGGACTTT 
CAGTTGGAAG TGACTCCTCA GAACATTACG CTGAACCCCG GCTTTGGTGG GCCTGTGTTT 
TCCTGGAGGG ACCAAGCTGT GCTGCGGCAG GACGGGGTGG TGGTGACCAT CAACAAGAAG 
AGGAACCTGG TGGTGTCTGT GGACGACGGT GGCACCTTTG AGGTTGTTTT GCACCGAGTG 
TGGAAGGGGA GCTCGGTCCA CCAGGACTTC CTGGGCTTCT ATGTGCTGGA CAGTCATCGG 
ATGTCAGCCC GGACGCACGG GCTGCTGGGG CAATTTTTCC ACCCCATCGG TTTTGAAGTG 
TCTGACATCC ACCCAGGCTC TGACCCCACA AAGCCAGATG CCACGATGGT GGTGAGGAAC 
CGCCGGCTCA CGGTCACCAG GGGTTTGCAA AAAGACTACA GCAAGGACCC GTGGCATGGG 
GCCGAGGTGT CCTGCTGGTT CATTCACAAC AATGGGGCTG GACTCATCGA TGGTGCCTAC 
ACTGATTATA TCGTCCCCGA CATCTTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001159906.1
CDS	296..2605
Translation	MEQFTIHLTVNPQSKVTFQLTYEEVLKRNHMQYEIVIKVKPKQLVHHFEIDVDIFEPQGISKLDAQASFLPKELAAQTIKKSFSGKKGHVLFRPTVSQQQSCPTCSTSLLNGHFKVTYDVSRDKICDLLVANNHFAHFFAPQNLTNMNKNVVFVIDISGSMRGQKVKQTKEALLKILGDMQPGDYFDLVLFGTRVQSWKGSLVQASEANLQAAQDFVRGFSLDEATNLNGGLLRGIEILNQVQESLPELSNHASILIMLTDGDPTEGVTDRSQILKNVRNAIRGRFPLYNLGFGHNVDFNFLEVMSMENNGRAQRIYEDHDATQQLQGFYSQVAKPLLVDVDLQYPQDAVLALTQNHHKQYYEGSEIVVAGRIADNKQSSFKADVQAHGEGQEFSITCLVDEEEMKKLLRERGHMLENHVERLWAYLTIQELLAKRMKVDREERANLSSQALQMSLDYGFVTPLTSMSIRGMADQDGLKPTIDKPSEDSPPLEMLGPRRTFVLSALQPSPTHSSSNTQRLPDRVTGVDTDPHFIIHVPQKEDTLCFNINEEPGVILSLVQDPNTGFSVNGQLIGNKARSPGQHDGTYFGRLGIANPATDFQLEVTPQNITLNPGFGGPVFSWRDQAVLRQDGVVVTINKKRNLVVSVDDGGTFEVVLHRVWKGSSVHQDFLGFYVLDSHRMSARTHGLLGQFFHPIGFEVSDIHPGSDPTKPDATMVVRNRRLTVTRGLQKDYSKDPWHGAEVSCWFIHNNGAGLIDGAYTDYIVPDIF

Target ORF information:

RefSeq Version	NM_001166434.2
Organism	Homo sapiens(human)
Definition	Homo sapiens inter-alpha-trypsin inhibitor heavy chain 1 (ITIH1), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001166434.2

ORF Insert Sequence:

ATGGAGCAAT TCACCATCCA CCTCACCGTC AATCCCCAGA GCAAGGTCAC GTTTCAGCTG 
ACTTATGAGG AAGTGCTGAA GAGAAACCAT ATGCAGTATG AAATTGTCAT CAAAGTCAAG 
CCCAAGCAGC TGGTGCATCA TTTTGAGATT GATGTGGACA TCTTCGAGCC CCAGGGGATC 
AGCAAGCTGG ATGCCCAGGC CTCTTTCCTG CCGAAGGAAC TGGCAGCCCA AACTATCAAG 
AAGTCCTTCT CAGGAAAAAA GGGTCATGTG CTGTTCCGTC CCACCGTGAG CCAGCAGCAG 
TCCTGCCCCA CATGCTCTAC ATCCTTACTG AACGGGCACT TCAAGGTGAC CTACGATGTC 
AGTCGAGACA AGATCTGCGA CCTCCTGGTG GCCAATAACC ACTTTGCCCA CTTCTTTGCC 
CCCCAAAACC TGACAAACAT GAACAAGAAC GTGGTTTTTG TGATTGACAT CAGTGGCTCC 
ATGAGAGGCC AGAAAGTGAA GCAGACCAAG GAGGCACTCC TTAAAATTCT GGGGGACATG 
CAGCCAGGGG ACTACTTTGA CCTGGTTCTT TTTGGGACTC GAGTACAATC GTGGAAGGGC 
TCGCTGGTGC AAGCATCTGA GGCCAACCTA CAAGCAGCTC AAGACTTTGT GCGGGGCTTT 
TCCCTGGATG AGGCCACAAA CCTGAATGGA GGTTTGCTCC GGGGAATTGA GATCTTGAAC 
CAAGTTCAGG AAAGCCTCCC AGAACTCAGC AACCATGCCT CAATACTCAT CATGTTGACA 
GATGGCGATC CCACAGAGGG GGTGACGGAC CGTTCCCAAA TCCTCAAGAA CGTCCGCAAC 
GCCATCCGGG GCAGGTTCCC GCTCTACAAC CTGGGTTTCG GCCACAATGT GGACTTTAAC 
TTTCTGGAGG TCATGTCCAT GGAGAACAAC GGACGGGCCC AGAGAATCTA CGAGGACCAT 
GATGCCACCC AGCAGCTGCA GGGTTTCTAC AGCCAGGTAG CCAAACCCCT GCTGGTGGAT 
GTGGATTTGC AGTACCCCCA GGATGCTGTC TTGGCCCTGA CCCAGAACCA CCATAAACAG 
TACTACGAAG GCTCAGAGAT TGTGGTGGCC GGGCGCATTG CTGACAACAA ACAGAGCAGC 
TTCAAGGCTG ATGTGCAGGC CCATGGGGAG GGACAAGAAT TCAGTATAAC CTGCCTAGTG 
GATGAGGAGG AGATGAAGAA ACTGCTCCGA GAGCGTGGCC ACATGCTGGA GAACCACGTC 
GAGCGCCTCT GGGCCTACCT CACCATCCAG GAGCTGCTGG CCAAGCGGAT GAAGGTGGAC 
AGGGAGGAGA GGGCCAACCT GTCATCCCAG GCCCTGCAGA TGTCGCTGGA CTATGGGTTT 
GTGACCCCAC TGACCTCCAT GAGCATCAGG GGCATGGCGG ACCAGGACGG CCTGAAGCCC 
ACCATCGACA AGCCCTCAGA GGATTCTCCG CCTTTGGAGA TGCTGGGACC CAGAAGGACG 
TTCGTGCTGT CAGCCTTGCA GCCTTCTCCT ACTCATTCCA GCTCCAATAC CCAGCGGCTG 
CCAGACCGAG TGACCGGCGT GGACACAGAC CCTCACTTCA TCATCCACGT GCCCCAGAAA 
GAGGACACCC TGTGCTTCAA CATCAATGAG GAGCCTGGTG TTATCCTGAG CCTGGTACAG 
GACCCCAACA CAGGCTTCTC AGTGAATGGA CAGCTCATTG GCAACAAGGC CAGGAGCCCT 
GGGCAGCATG ACGGCACGTA CTTCGGGCGG CTGGGAATCG CAAACCCTGC CACGGACTTT 
CAGTTGGAAG TGACTCCTCA GAACATTACG CTGAACCCCG GCTTTGGTGG GCCTGTGTTT 
TCCTGGAGGG ACCAAGCTGT GCTGCGGCAG GACGGGGTGG TGGTGACCAT CAACAAGAAG 
AGGAACCTGG TGGTGTCTGT GGACGACGGT GGCACCTTTG AGGTTGTTTT GCACCGAGTG 
TGGAAGGGGA GCTCGGTCCA CCAGGACTTC CTGGGCTTCT ATGTGCTGGA CAGTCATCGG 
ATGTCAGCCC GGACGCACGG GCTGCTGGGG CAATTTTTCC ACCCCATCGG TTTTGAAGTG 
TCTGACATCC ACCCAGGCTC TGACCCCACA AAGCCAGATG CCACGATGGT GGTGAGGAAC 
CGCCGGCTCA CGGTCACCAG GGGTTTGCAA AAAGACTACA GCAAGGACCC GTGGCATGGG 
GCCGAGGTGT CCTGCTGGTT CATTCACAAC AATGGGGCTG GACTCATCGA TGGTGCCTAC 
ACTGATTATA TCGTCCCCGA CATCTTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ITIH1 ( NM_001166434.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_001159906.1 Homo sapiens inter-alpha-trypsin inhibitor heavy chain 1 (ITIH1), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu21901
Clone ID Related Accession (Same CDS sequence)	NM_001166434.2 , NM_001166434.3
Accession Version	NM_001166434.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2310bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-27
Organism	Homo sapiens(human)
Product	inter-alpha-trypsin inhibitor heavy chain H1 isoform b
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC006254.10, DB188130.1, AK298455.1, M18192.1, AK292750.1 and AA897466.1. On May 31, 2019 this sequence version replaced NM_001166434.2. Transcript Variant: This variant (2) differs in the 5' UTR and coding sequence compared to variant 1. The resulting isoform (b) has a shorter N-terminus and lacks a predicted signal peptide compared to isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK298455.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2145122, SAMEA2155590 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGAGCAAT TCACCATCCA CCTCACCGTC AATCCCCAGA GCAAGGTCAC GTTTCAGCTG 
ACTTATGAGG AAGTGCTGAA GAGAAACCAT ATGCAGTATG AAATTGTCAT CAAAGTCAAG 
CCCAAGCAGC TGGTGCATCA TTTTGAGATT GATGTGGACA TCTTCGAGCC CCAGGGGATC 
AGCAAGCTGG ATGCCCAGGC CTCTTTCCTG CCGAAGGAAC TGGCAGCCCA AACTATCAAG 
AAGTCCTTCT CAGGAAAAAA GGGTCATGTG CTGTTCCGTC CCACCGTGAG CCAGCAGCAG 
TCCTGCCCCA CATGCTCTAC ATCCTTACTG AACGGGCACT TCAAGGTGAC CTACGATGTC 
AGTCGAGACA AGATCTGCGA CCTCCTGGTG GCCAATAACC ACTTTGCCCA CTTCTTTGCC 
CCCCAAAACC TGACAAACAT GAACAAGAAC GTGGTTTTTG TGATTGACAT CAGTGGCTCC 
ATGAGAGGCC AGAAAGTGAA GCAGACCAAG GAGGCACTCC TTAAAATTCT GGGGGACATG 
CAGCCAGGGG ACTACTTTGA CCTGGTTCTT TTTGGGACTC GAGTACAATC GTGGAAGGGC 
TCGCTGGTGC AAGCATCTGA GGCCAACCTA CAAGCAGCTC AAGACTTTGT GCGGGGCTTT 
TCCCTGGATG AGGCCACAAA CCTGAATGGA GGTTTGCTCC GGGGAATTGA GATCTTGAAC 
CAAGTTCAGG AAAGCCTCCC AGAACTCAGC AACCATGCCT CAATACTCAT CATGTTGACA 
GATGGCGATC CCACAGAGGG GGTGACGGAC CGTTCCCAAA TCCTCAAGAA CGTCCGCAAC 
GCCATCCGGG GCAGGTTCCC GCTCTACAAC CTGGGTTTCG GCCACAATGT GGACTTTAAC 
TTTCTGGAGG TCATGTCCAT GGAGAACAAC GGACGGGCCC AGAGAATCTA CGAGGACCAT 
GATGCCACCC AGCAGCTGCA GGGTTTCTAC AGCCAGGTAG CCAAACCCCT GCTGGTGGAT 
GTGGATTTGC AGTACCCCCA GGATGCTGTC TTGGCCCTGA CCCAGAACCA CCATAAACAG 
TACTACGAAG GCTCAGAGAT TGTGGTGGCC GGGCGCATTG CTGACAACAA ACAGAGCAGC 
TTCAAGGCTG ATGTGCAGGC CCATGGGGAG GGACAAGAAT TCAGTATAAC CTGCCTAGTG 
GATGAGGAGG AGATGAAGAA ACTGCTCCGA GAGCGTGGCC ACATGCTGGA GAACCACGTC 
GAGCGCCTCT GGGCCTACCT CACCATCCAG GAGCTGCTGG CCAAGCGGAT GAAGGTGGAC 
AGGGAGGAGA GGGCCAACCT GTCATCCCAG GCCCTGCAGA TGTCGCTGGA CTATGGGTTT 
GTGACCCCAC TGACCTCCAT GAGCATCAGG GGCATGGCGG ACCAGGACGG CCTGAAGCCC 
ACCATCGACA AGCCCTCAGA GGATTCTCCG CCTTTGGAGA TGCTGGGACC CAGAAGGACG 
TTCGTGCTGT CAGCCTTGCA GCCTTCTCCT ACTCATTCCA GCTCCAATAC CCAGCGGCTG 
CCAGACCGAG TGACCGGCGT GGACACAGAC CCTCACTTCA TCATCCACGT GCCCCAGAAA 
GAGGACACCC TGTGCTTCAA CATCAATGAG GAGCCTGGTG TTATCCTGAG CCTGGTACAG 
GACCCCAACA CAGGCTTCTC AGTGAATGGA CAGCTCATTG GCAACAAGGC CAGGAGCCCT 
GGGCAGCATG ACGGCACGTA CTTCGGGCGG CTGGGAATCG CAAACCCTGC CACGGACTTT 
CAGTTGGAAG TGACTCCTCA GAACATTACG CTGAACCCCG GCTTTGGTGG GCCTGTGTTT 
TCCTGGAGGG ACCAAGCTGT GCTGCGGCAG GACGGGGTGG TGGTGACCAT CAACAAGAAG 
AGGAACCTGG TGGTGTCTGT GGACGACGGT GGCACCTTTG AGGTTGTTTT GCACCGAGTG 
TGGAAGGGGA GCTCGGTCCA CCAGGACTTC CTGGGCTTCT ATGTGCTGGA CAGTCATCGG 
ATGTCAGCCC GGACGCACGG GCTGCTGGGG CAATTTTTCC ACCCCATCGG TTTTGAAGTG 
TCTGACATCC ACCCAGGCTC TGACCCCACA AAGCCAGATG CCACGATGGT GGTGAGGAAC 
CGCCGGCTCA CGGTCACCAG GGGTTTGCAA AAAGACTACA GCAAGGACCC GTGGCATGGG 
GCCGAGGTGT CCTGCTGGTT CATTCACAAC AATGGGGCTG GACTCATCGA TGGTGCCTAC 
ACTGATTATA TCGTCCCCGA CATCTTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001159906.1
CDS	303..2612
Translation	MEQFTIHLTVNPQSKVTFQLTYEEVLKRNHMQYEIVIKVKPKQLVHHFEIDVDIFEPQGISKLDAQASFLPKELAAQTIKKSFSGKKGHVLFRPTVSQQQSCPTCSTSLLNGHFKVTYDVSRDKICDLLVANNHFAHFFAPQNLTNMNKNVVFVIDISGSMRGQKVKQTKEALLKILGDMQPGDYFDLVLFGTRVQSWKGSLVQASEANLQAAQDFVRGFSLDEATNLNGGLLRGIEILNQVQESLPELSNHASILIMLTDGDPTEGVTDRSQILKNVRNAIRGRFPLYNLGFGHNVDFNFLEVMSMENNGRAQRIYEDHDATQQLQGFYSQVAKPLLVDVDLQYPQDAVLALTQNHHKQYYEGSEIVVAGRIADNKQSSFKADVQAHGEGQEFSITCLVDEEEMKKLLRERGHMLENHVERLWAYLTIQELLAKRMKVDREERANLSSQALQMSLDYGFVTPLTSMSIRGMADQDGLKPTIDKPSEDSPPLEMLGPRRTFVLSALQPSPTHSSSNTQRLPDRVTGVDTDPHFIIHVPQKEDTLCFNINEEPGVILSLVQDPNTGFSVNGQLIGNKARSPGQHDGTYFGRLGIANPATDFQLEVTPQNITLNPGFGGPVFSWRDQAVLRQDGVVVTINKKRNLVVSVDDGGTFEVVLHRVWKGSSVHQDFLGFYVLDSHRMSARTHGLLGQFFHPIGFEVSDIHPGSDPTKPDATMVVRNRRLTVTRGLQKDYSKDPWHGAEVSCWFIHNNGAGLIDGAYTDYIVPDIF

Target ORF information:

RefSeq Version	NM_001166434.3
Organism	Homo sapiens(human)
Definition	Homo sapiens inter-alpha-trypsin inhibitor heavy chain 1 (ITIH1), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001166434.3

ORF Insert Sequence:

ATGGAGCAAT TCACCATCCA CCTCACCGTC AATCCCCAGA GCAAGGTCAC GTTTCAGCTG 
ACTTATGAGG AAGTGCTGAA GAGAAACCAT ATGCAGTATG AAATTGTCAT CAAAGTCAAG 
CCCAAGCAGC TGGTGCATCA TTTTGAGATT GATGTGGACA TCTTCGAGCC CCAGGGGATC 
AGCAAGCTGG ATGCCCAGGC CTCTTTCCTG CCGAAGGAAC TGGCAGCCCA AACTATCAAG 
AAGTCCTTCT CAGGAAAAAA GGGTCATGTG CTGTTCCGTC CCACCGTGAG CCAGCAGCAG 
TCCTGCCCCA CATGCTCTAC ATCCTTACTG AACGGGCACT TCAAGGTGAC CTACGATGTC 
AGTCGAGACA AGATCTGCGA CCTCCTGGTG GCCAATAACC ACTTTGCCCA CTTCTTTGCC 
CCCCAAAACC TGACAAACAT GAACAAGAAC GTGGTTTTTG TGATTGACAT CAGTGGCTCC 
ATGAGAGGCC AGAAAGTGAA GCAGACCAAG GAGGCACTCC TTAAAATTCT GGGGGACATG 
CAGCCAGGGG ACTACTTTGA CCTGGTTCTT TTTGGGACTC GAGTACAATC GTGGAAGGGC 
TCGCTGGTGC AAGCATCTGA GGCCAACCTA CAAGCAGCTC AAGACTTTGT GCGGGGCTTT 
TCCCTGGATG AGGCCACAAA CCTGAATGGA GGTTTGCTCC GGGGAATTGA GATCTTGAAC 
CAAGTTCAGG AAAGCCTCCC AGAACTCAGC AACCATGCCT CAATACTCAT CATGTTGACA 
GATGGCGATC CCACAGAGGG GGTGACGGAC CGTTCCCAAA TCCTCAAGAA CGTCCGCAAC 
GCCATCCGGG GCAGGTTCCC GCTCTACAAC CTGGGTTTCG GCCACAATGT GGACTTTAAC 
TTTCTGGAGG TCATGTCCAT GGAGAACAAC GGACGGGCCC AGAGAATCTA CGAGGACCAT 
GATGCCACCC AGCAGCTGCA GGGTTTCTAC AGCCAGGTAG CCAAACCCCT GCTGGTGGAT 
GTGGATTTGC AGTACCCCCA GGATGCTGTC TTGGCCCTGA CCCAGAACCA CCATAAACAG 
TACTACGAAG GCTCAGAGAT TGTGGTGGCC GGGCGCATTG CTGACAACAA ACAGAGCAGC 
TTCAAGGCTG ATGTGCAGGC CCATGGGGAG GGACAAGAAT TCAGTATAAC CTGCCTAGTG 
GATGAGGAGG AGATGAAGAA ACTGCTCCGA GAGCGTGGCC ACATGCTGGA GAACCACGTC 
GAGCGCCTCT GGGCCTACCT CACCATCCAG GAGCTGCTGG CCAAGCGGAT GAAGGTGGAC 
AGGGAGGAGA GGGCCAACCT GTCATCCCAG GCCCTGCAGA TGTCGCTGGA CTATGGGTTT 
GTGACCCCAC TGACCTCCAT GAGCATCAGG GGCATGGCGG ACCAGGACGG CCTGAAGCCC 
ACCATCGACA AGCCCTCAGA GGATTCTCCG CCTTTGGAGA TGCTGGGACC CAGAAGGACG 
TTCGTGCTGT CAGCCTTGCA GCCTTCTCCT ACTCATTCCA GCTCCAATAC CCAGCGGCTG 
CCAGACCGAG TGACCGGCGT GGACACAGAC CCTCACTTCA TCATCCACGT GCCCCAGAAA 
GAGGACACCC TGTGCTTCAA CATCAATGAG GAGCCTGGTG TTATCCTGAG CCTGGTACAG 
GACCCCAACA CAGGCTTCTC AGTGAATGGA CAGCTCATTG GCAACAAGGC CAGGAGCCCT 
GGGCAGCATG ACGGCACGTA CTTCGGGCGG CTGGGAATCG CAAACCCTGC CACGGACTTT 
CAGTTGGAAG TGACTCCTCA GAACATTACG CTGAACCCCG GCTTTGGTGG GCCTGTGTTT 
TCCTGGAGGG ACCAAGCTGT GCTGCGGCAG GACGGGGTGG TGGTGACCAT CAACAAGAAG 
AGGAACCTGG TGGTGTCTGT GGACGACGGT GGCACCTTTG AGGTTGTTTT GCACCGAGTG 
TGGAAGGGGA GCTCGGTCCA CCAGGACTTC CTGGGCTTCT ATGTGCTGGA CAGTCATCGG 
ATGTCAGCCC GGACGCACGG GCTGCTGGGG CAATTTTTCC ACCCCATCGG TTTTGAAGTG 
TCTGACATCC ACCCAGGCTC TGACCCCACA AAGCCAGATG CCACGATGGT GGTGAGGAAC 
CGCCGGCTCA CGGTCACCAG GGGTTTGCAA AAAGACTACA GCAAGGACCC GTGGCATGGG 
GCCGAGGTGT CCTGCTGGTT CATTCACAAC AATGGGGCTG GACTCATCGA TGGTGCCTAC 
ACTGATTATA TCGTCCCCGA CATCTTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Characterization of the Extracellular Matrix of Normal and Diseased Tissues Using Proteomics.
Journal of proteome research16(8)3083-3091(2017 Aug)
Naba A,Pearce OMT,Del Rosario A,Ma D,Ding H,Rajeeve V,Cutillas PR,Balkwill FR,Hynes RO

Thrombin Cleavage of Inter-?-inhibitor Heavy Chain 1 Regulates Leukocyte Binding to an Inflammatory Hyaluronan Matrix.
The Journal of biological chemistry291(47)24324-24334(2016 Nov)
Petrey AC,de la Motte CA

The Compact and Biologically Relevant Structure of Inter-?-inhibitor Is Maintained by the Chondroitin Sulfate Chain and Divalent Cations.
The Journal of biological chemistry291(9)4658-70(2016 Feb)
Scavenius C,Nikolajsen CL,Stenvang M,Th?gersen IB,Wyro?emski ?,Wisniewski HG,Otzen DE,Sanggaard KW,Enghild JJ

Common variants near ABCA1, AFAP1 and GMDS confer risk of primary open-angle glaucoma.
Nature genetics46(10)1120-1125(2014 Oct)
Gharahkhani P,Burdon KP,Fogarty R,Sharma S,Hewitt AW,Martin S,Law MH,Cremin K,Bailey JNC,Loomis SJ,Pasquale LR,Haines JL,Hauser MA,Viswanathan AC,McGuffin P,Topouzis F,Foster PJ,Graham SL,Casson RJ,Chehade M,White AJ,Zhou T,Souzeau E,Landers J,Fitzgerald JT,Klebe S,Ruddle JB,Goldberg I,Healey PR,,Mills RA,Wang JJ,Montgomery GW,Martin NG,RadfordSmith G,Whiteman DC,Brown MA,Wiggs JL,Mackey DA,Mitchell P,MacGregor S,Craig JE

Biological insights from 108 schizophrenia-associated genetic loci.
Nature511(7510)421-7(2014 Jul)

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ITIH1 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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