JCHAIN cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	JCHAIN
Entrez Gene ID	3512
Full Name	joining chain of multimeric IgA and IgM
Synonyms	IGCJ,IGJ,JCH
General protein information	Preferred Names joining chain of multimeric IgA and IgM Names immunoglobulin J chain IgJ chain J chain immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 4 Map Location: 4q13.3
Disorder MIM:	147790

mRNA and Protein(s)

mRNA	Protein	Name
XM_011531926.1	XP_011530228.1	immunoglobulin J chain isoform X1
XM_011531925.1	XP_011530227.1	immunoglobulin J chain isoform X1
XM_006714212.2	XP_006714275.1	immunoglobulin J chain isoform X1
XM_006714211.1	XP_006714274.1	immunoglobulin J chain isoform X1
NM_144646.4	NP_653247.1	immunoglobulin J chain precursor
XM_006714211.2	XP_006714274.1	immunoglobulin J chain isoform X1
NM_144646.3	NP_653247.1	immunoglobulin J chain precursor

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	IGJ	XP_532398.2
Gallus gallus (chicken)	IGJ	NP_989594.1
Pan troglodytes (chimpanzee)	IGJ	XP_517248.1
	IGJ	XP_001105782.1
Xenopus tropicalis (tropical clawed frog)	LOC101734759	XP_004911140.1
Homo sapiens (human)	IGJ	NP_653247.1
Bos taurus (cattle)	IGJ	NP_786967.1
Mus musculus (house mouse)	Igj	NP_690052.2

Gene Ontology
Bibliography

Related articles in PubMed

High expression of ID family and IGJ genes signature as predictor of low induction treatment response and worst survival in adult Hispanic patients with B-acute lymphoblastic leukemia.
Cruz-Rodriguez N, Combita AL, Enciso LJ, Quijano SM, Pinzon PL, Lozano OC, Castillo JS, Li L, Bare?o J, Cardozo C, Solano J, Herrera MV, Cudris J, Zabaleta J
Journal of experimental & clinical cancer research : CR3564(2016 Apr)

Expression and glycoengineering of functionally active heteromultimeric IgM in plants.
Loos A, Gruber C, Altmann F, Mehofer U, Hensel F, Grandits M, Oostenbrink C, Stadlmayr G, Furtm?ller PG, Steinkellner H
Proceedings of the National Academy of Sciences of the United States of America111(17)6263-8(2014 Apr)

Characterization, quantification, and assessment of immune protection potential of secretory immunoglobulin A in colostrum samples from Saudi women.
Almogren A
Saudi medical journal34(10)1013-9(2013 Oct)

Shotgun proteomics reveals specific modulated protein patterns in tears of patients with primary open angle glaucoma na?ve to therapy.
Pieragostino D, Agnifili L, Fasanella V, D'Aguanno S, Mastropasqua R, Di Ilio C, Sacchetta P, Urbani A, Del Boccio P
Molecular bioSystems9(6)1108-16(2013 Jun)

Human J chain gene: chromosomal localization and associated restriction fragment length polymorphisms.
Max EE, McBride OW, Morton CC, Robinson MA
Proceedings of the National Academy of Sciences of the United States of America83(15)5592-6(1986 Aug)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Results show that ID1, ID3 and IGJ genes are highly expressed in adult B-ALL and correlate with poor prognosis in Hispanic patients.
Title: High expression of ID family and IGJ genes signature as predictor of low induction treatment response and worst survival in adult Hispanic patients with B-acute lymphoblastic leukemia.

TLR2 ligands induce CCR9 and CCR10 expression by circulating B-cells and increase their chemotaxis. TLR2 stimulation also induced J chain and IgA production demonstrating the induction of mucosal-like antibody secreting cells.
Title: Toll-like receptor 2 induces mucosal homing receptor expression and IgA production by human B cells.

Observational study of gene-disease association. (HuGE Navigator)
Title: New genetic associations detected in a host response study to hepatitis B vaccine.

The following JCHAIN gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the JCHAIN cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu13960	NM_144646.4 Latest version!	Homo sapiens joining chain of multimeric IgA and IgM (JCHAIN), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu13960	XM_011531926.1 Latest version!	Homo sapiens joining chain of multimeric IgA and IgM (JCHAIN), transcript variant X4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu13960	XM_011531925.1 Latest version!	Homo sapiens joining chain of multimeric IgA and IgM (JCHAIN), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu13960	XM_006714211.2 Latest version!	Homo sapiens joining chain of multimeric IgA and IgM (JCHAIN), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu13960	XM_006714212.2 Latest version!	Homo sapiens joining chain of multimeric IgA and IgM (JCHAIN), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
View Old Accession Versions >>
OHu13960	XM_006714211.1	Homo sapiens immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides (IGJ), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu13960	NM_144646.3	Homo sapiens joining chain of multimeric IgA and IgM (JCHAIN), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

JCHAIN ( NM_144646.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_653247.1 Homo sapiens joining chain of multimeric IgA and IgM (JCHAIN), mRNA.

Price & Availability↑

CloneID	OHu13960
Clone ID Related Accession (Same CDS sequence)	XM_011531926.1 , XM_011531925.1 , XM_006714212.2 , XM_006714211.1 , NM_144646.4 , XM_006714211.2 , NM_144646.3
Accession Version	NM_144646.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 480bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-30
Organism	Homo sapiens(human)
Product	immunoglobulin J chain precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BC038982.1, BP221304.1 and BP418109.1. On Nov 22, 2018 this sequence version replaced NM_144646.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1163655.34465.1, SRR1163655.579552.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA1968832 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000254801.9/ ENSP00000254801.4 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGAAGAACC ATTTGCTTTT CTGGGGAGTC CTGGCGGTTT TTATTAAGGC TGTTCATGTG 
AAAGCCCAAG AAGATGAAAG GATTGTTCTT GTTGACAACA AATGTAAGTG TGCCCGGATT 
ACTTCCAGGA TCATCCGTTC TTCCGAAGAT CCTAATGAGG ACATTGTGGA GAGAAACATC 
CGAATTATTG TTCCTCTGAA CAACAGGGAG AATATCTCTG ATCCCACCTC ACCATTGAGA 
ACCAGATTTG TGTACCATTT GTCTGACCTC TGTAAAAAAT GTGATCCTAC AGAAGTGGAG 
CTGGATAATC AGATAGTTAC TGCTACCCAG AGCAATATCT GTGATGAAGA CAGTGCTACA 
GAGACCTGCT ACACTTATGA CAGAAACAAG TGCTACACAG CTGTGGTCCC ACTCGTATAT 
GGTGGTGAGA CCAAAATGGT GGAAACAGCC TTAACCCCAG ATGCCTGCTA TCCTGACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_653247.1
CDS	19..498
Translation	MKNHLLFWGVLAVFIKAVHVKAQEDERIVLVDNKCKCARITSRIIRSSEDPNEDIVERNIRIIVPLNNRENISDPTSPLRTRFVYHLSDLCKKCDPTEVELDNQIVTATQSNICDEDSATETCYTYDRNKCYTAVVPLVYGGETKMVETALTPDACYPD

Target ORF information:

RefSeq Version	NM_144646.4
Organism	Homo sapiens(human)
Definition	Homo sapiens joining chain of multimeric IgA and IgM (JCHAIN), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_144646.4

ORF Insert Sequence:

ATGAAGAACC ATTTGCTTTT CTGGGGAGTC CTGGCGGTTT TTATTAAGGC TGTTCATGTG 
AAAGCCCAAG AAGATGAAAG GATTGTTCTT GTTGACAACA AATGTAAGTG TGCCCGGATT 
ACTTCCAGGA TCATCCGTTC TTCCGAAGAT CCTAATGAGG ACATTGTGGA GAGAAACATC 
CGAATTATTG TTCCTCTGAA CAACAGGGAG AATATCTCTG ATCCCACCTC ACCATTGAGA 
ACCAGATTTG TGTACCATTT GTCTGACCTC TGTAAAAAAT GTGATCCTAC AGAAGTGGAG 
CTGGATAATC AGATAGTTAC TGCTACCCAG AGCAATATCT GTGATGAAGA CAGTGCTACA 
GAGACCTGCT ACACTTATGA CAGAAACAAG TGCTACACAG CTGTGGTCCC ACTCGTATAT 
GGTGGTGAGA CCAAAATGGT GGAAACAGCC TTAACCCCAG ATGCCTGCTA TCCTGACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

JCHAIN ( NM_144646.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_653247.1 Homo sapiens joining chain of multimeric IgA and IgM (JCHAIN), mRNA.

Price & Availability↑

CloneID	OHu13960
Clone ID Related Accession (Same CDS sequence)	XM_011531926.1 , XM_011531925.1 , XM_006714212.2 , XM_006714211.1 , NM_144646.4 , XM_006714211.2 , NM_144646.3
Accession Version	NM_144646.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 480bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Homo sapiens(human)
Product	immunoglobulin J chain precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BP261870.1, BC038982.1, BP221304.1 and BP418109.1. On Jun 7, 2008 this sequence version replaced NM_144646.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1163655.681242.1, SRR1163655.274279.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA1968832 [ECO:0000348] ##Evidence-Data-END##

ATGAAGAACC ATTTGCTTTT CTGGGGAGTC CTGGCGGTTT TTATTAAGGC TGTTCATGTG 
AAAGCCCAAG AAGATGAAAG GATTGTTCTT GTTGACAACA AATGTAAGTG TGCCCGGATT 
ACTTCCAGGA TCATCCGTTC TTCCGAAGAT CCTAATGAGG ACATTGTGGA GAGAAACATC 
CGAATTATTG TTCCTCTGAA CAACAGGGAG AATATCTCTG ATCCCACCTC ACCATTGAGA 
ACCAGATTTG TGTACCATTT GTCTGACCTC TGTAAAAAAT GTGATCCTAC AGAAGTGGAG 
CTGGATAATC AGATAGTTAC TGCTACCCAG AGCAATATCT GTGATGAAGA CAGTGCTACA 
GAGACCTGCT ACACTTATGA CAGAAACAAG TGCTACACAG CTGTGGTCCC ACTCGTATAT 
GGTGGTGAGA CCAAAATGGT GGAAACAGCC TTAACCCCAG ATGCCTGCTA TCCTGACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_653247.1
CDS	142..621
Translation	MKNHLLFWGVLAVFIKAVHVKAQEDERIVLVDNKCKCARITSRIIRSSEDPNEDIVERNIRIIVPLNNRENISDPTSPLRTRFVYHLSDLCKKCDPTEVELDNQIVTATQSNICDEDSATETCYTYDRNKCYTAVVPLVYGGETKMVETALTPDACYPD

Target ORF information:

RefSeq Version	NM_144646.3
Organism	Homo sapiens(human)
Definition	Homo sapiens joining chain of multimeric IgA and IgM (JCHAIN), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_144646.3

ORF Insert Sequence:

ATGAAGAACC ATTTGCTTTT CTGGGGAGTC CTGGCGGTTT TTATTAAGGC TGTTCATGTG 
AAAGCCCAAG AAGATGAAAG GATTGTTCTT GTTGACAACA AATGTAAGTG TGCCCGGATT 
ACTTCCAGGA TCATCCGTTC TTCCGAAGAT CCTAATGAGG ACATTGTGGA GAGAAACATC 
CGAATTATTG TTCCTCTGAA CAACAGGGAG AATATCTCTG ATCCCACCTC ACCATTGAGA 
ACCAGATTTG TGTACCATTT GTCTGACCTC TGTAAAAAAT GTGATCCTAC AGAAGTGGAG 
CTGGATAATC AGATAGTTAC TGCTACCCAG AGCAATATCT GTGATGAAGA CAGTGCTACA 
GAGACCTGCT ACACTTATGA CAGAAACAAG TGCTACACAG CTGTGGTCCC ACTCGTATAT 
GGTGGTGAGA CCAAAATGGT GGAAACAGCC TTAACCCCAG ATGCCTGCTA TCCTGACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

JCHAIN ( XM_011531926.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_011530228.1 Homo sapiens joining chain of multimeric IgA and IgM (JCHAIN), transcript variant X4, mRNA.

Price & Availability↑

CloneID	OHu13960
Clone ID Related Accession (Same CDS sequence)	XM_011531926.1 , XM_011531925.1 , XM_006714212.2 , XM_006714211.1 , NM_144646.4 , XM_006714211.2 , NM_144646.3
Accession Version	XM_011531926.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 480bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	immunoglobulin J chain isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000004.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAAGAACC ATTTGCTTTT CTGGGGAGTC CTGGCGGTTT TTATTAAGGC TGTTCATGTG 
AAAGCCCAAG AAGATGAAAG GATTGTTCTT GTTGACAACA AATGTAAGTG TGCCCGGATT 
ACTTCCAGGA TCATCCGTTC TTCCGAAGAT CCTAATGAGG ACATTGTGGA GAGAAACATC 
CGAATTATTG TTCCTCTGAA CAACAGGGAG AATATCTCTG ATCCCACCTC ACCATTGAGA 
ACCAGATTTG TGTACCATTT GTCTGACCTC TGTAAAAAAT GTGATCCTAC AGAAGTGGAG 
CTGGATAATC AGATAGTTAC TGCTACCCAG AGCAATATCT GTGATGAAGA CAGTGCTACA 
GAGACCTGCT ACACTTATGA CAGAAACAAG TGCTACACAG CTGTGGTCCC ACTCGTATAT 
GGTGGTGAGA CCAAAATGGT GGAAACAGCC TTAACCCCAG ATGCCTGCTA TCCTGACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011530228.1
CDS	44..523
Translation	MKNHLLFWGVLAVFIKAVHVKAQEDERIVLVDNKCKCARITSRIIRSSEDPNEDIVERNIRIIVPLNNRENISDPTSPLRTRFVYHLSDLCKKCDPTEVELDNQIVTATQSNICDEDSATETCYTYDRNKCYTAVVPLVYGGETKMVETALTPDACYPD

Target ORF information:

RefSeq Version	XM_011531926.1
Organism	Homo sapiens(human)
Definition	Homo sapiens joining chain of multimeric IgA and IgM (JCHAIN), transcript variant X4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011531926.1

ORF Insert Sequence:

ATGAAGAACC ATTTGCTTTT CTGGGGAGTC CTGGCGGTTT TTATTAAGGC TGTTCATGTG 
AAAGCCCAAG AAGATGAAAG GATTGTTCTT GTTGACAACA AATGTAAGTG TGCCCGGATT 
ACTTCCAGGA TCATCCGTTC TTCCGAAGAT CCTAATGAGG ACATTGTGGA GAGAAACATC 
CGAATTATTG TTCCTCTGAA CAACAGGGAG AATATCTCTG ATCCCACCTC ACCATTGAGA 
ACCAGATTTG TGTACCATTT GTCTGACCTC TGTAAAAAAT GTGATCCTAC AGAAGTGGAG 
CTGGATAATC AGATAGTTAC TGCTACCCAG AGCAATATCT GTGATGAAGA CAGTGCTACA 
GAGACCTGCT ACACTTATGA CAGAAACAAG TGCTACACAG CTGTGGTCCC ACTCGTATAT 
GGTGGTGAGA CCAAAATGGT GGAAACAGCC TTAACCCCAG ATGCCTGCTA TCCTGACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

JCHAIN ( XM_011531925.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_011530227.1 Homo sapiens joining chain of multimeric IgA and IgM (JCHAIN), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu13960
Clone ID Related Accession (Same CDS sequence)	XM_011531926.1 , XM_011531925.1 , XM_006714212.2 , XM_006714211.1 , NM_144646.4 , XM_006714211.2 , NM_144646.3
Accession Version	XM_011531925.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 480bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	immunoglobulin J chain isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000004.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAAGAACC ATTTGCTTTT CTGGGGAGTC CTGGCGGTTT TTATTAAGGC TGTTCATGTG 
AAAGCCCAAG AAGATGAAAG GATTGTTCTT GTTGACAACA AATGTAAGTG TGCCCGGATT 
ACTTCCAGGA TCATCCGTTC TTCCGAAGAT CCTAATGAGG ACATTGTGGA GAGAAACATC 
CGAATTATTG TTCCTCTGAA CAACAGGGAG AATATCTCTG ATCCCACCTC ACCATTGAGA 
ACCAGATTTG TGTACCATTT GTCTGACCTC TGTAAAAAAT GTGATCCTAC AGAAGTGGAG 
CTGGATAATC AGATAGTTAC TGCTACCCAG AGCAATATCT GTGATGAAGA CAGTGCTACA 
GAGACCTGCT ACACTTATGA CAGAAACAAG TGCTACACAG CTGTGGTCCC ACTCGTATAT 
GGTGGTGAGA CCAAAATGGT GGAAACAGCC TTAACCCCAG ATGCCTGCTA TCCTGACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011530227.1
CDS	44..523
Translation	MKNHLLFWGVLAVFIKAVHVKAQEDERIVLVDNKCKCARITSRIIRSSEDPNEDIVERNIRIIVPLNNRENISDPTSPLRTRFVYHLSDLCKKCDPTEVELDNQIVTATQSNICDEDSATETCYTYDRNKCYTAVVPLVYGGETKMVETALTPDACYPD

Target ORF information:

RefSeq Version	XM_011531925.1
Organism	Homo sapiens(human)
Definition	Homo sapiens joining chain of multimeric IgA and IgM (JCHAIN), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011531925.1

ORF Insert Sequence:

ATGAAGAACC ATTTGCTTTT CTGGGGAGTC CTGGCGGTTT TTATTAAGGC TGTTCATGTG 
AAAGCCCAAG AAGATGAAAG GATTGTTCTT GTTGACAACA AATGTAAGTG TGCCCGGATT 
ACTTCCAGGA TCATCCGTTC TTCCGAAGAT CCTAATGAGG ACATTGTGGA GAGAAACATC 
CGAATTATTG TTCCTCTGAA CAACAGGGAG AATATCTCTG ATCCCACCTC ACCATTGAGA 
ACCAGATTTG TGTACCATTT GTCTGACCTC TGTAAAAAAT GTGATCCTAC AGAAGTGGAG 
CTGGATAATC AGATAGTTAC TGCTACCCAG AGCAATATCT GTGATGAAGA CAGTGCTACA 
GAGACCTGCT ACACTTATGA CAGAAACAAG TGCTACACAG CTGTGGTCCC ACTCGTATAT 
GGTGGTGAGA CCAAAATGGT GGAAACAGCC TTAACCCCAG ATGCCTGCTA TCCTGACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

JCHAIN ( XM_006714212.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_006714275.1 Homo sapiens joining chain of multimeric IgA and IgM (JCHAIN), transcript variant X3, mRNA.

Price & Availability↑

CloneID	OHu13960
Clone ID Related Accession (Same CDS sequence)	XM_011531926.1 , XM_011531925.1 , XM_006714212.2 , XM_006714211.1 , NM_144646.4 , XM_006714211.2 , NM_144646.3
Accession Version	XM_006714212.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 480bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	immunoglobulin J chain isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000004.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 12, 2015 this sequence version replaced XM_006714212.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAAGAACC ATTTGCTTTT CTGGGGAGTC CTGGCGGTTT TTATTAAGGC TGTTCATGTG 
AAAGCCCAAG AAGATGAAAG GATTGTTCTT GTTGACAACA AATGTAAGTG TGCCCGGATT 
ACTTCCAGGA TCATCCGTTC TTCCGAAGAT CCTAATGAGG ACATTGTGGA GAGAAACATC 
CGAATTATTG TTCCTCTGAA CAACAGGGAG AATATCTCTG ATCCCACCTC ACCATTGAGA 
ACCAGATTTG TGTACCATTT GTCTGACCTC TGTAAAAAAT GTGATCCTAC AGAAGTGGAG 
CTGGATAATC AGATAGTTAC TGCTACCCAG AGCAATATCT GTGATGAAGA CAGTGCTACA 
GAGACCTGCT ACACTTATGA CAGAAACAAG TGCTACACAG CTGTGGTCCC ACTCGTATAT 
GGTGGTGAGA CCAAAATGGT GGAAACAGCC TTAACCCCAG ATGCCTGCTA TCCTGACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006714275.1
CDS	44..523
Translation	MKNHLLFWGVLAVFIKAVHVKAQEDERIVLVDNKCKCARITSRIIRSSEDPNEDIVERNIRIIVPLNNRENISDPTSPLRTRFVYHLSDLCKKCDPTEVELDNQIVTATQSNICDEDSATETCYTYDRNKCYTAVVPLVYGGETKMVETALTPDACYPD

Target ORF information:

RefSeq Version	XM_006714212.2
Organism	Homo sapiens(human)
Definition	Homo sapiens joining chain of multimeric IgA and IgM (JCHAIN), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006714212.2

ORF Insert Sequence:

ATGAAGAACC ATTTGCTTTT CTGGGGAGTC CTGGCGGTTT TTATTAAGGC TGTTCATGTG 
AAAGCCCAAG AAGATGAAAG GATTGTTCTT GTTGACAACA AATGTAAGTG TGCCCGGATT 
ACTTCCAGGA TCATCCGTTC TTCCGAAGAT CCTAATGAGG ACATTGTGGA GAGAAACATC 
CGAATTATTG TTCCTCTGAA CAACAGGGAG AATATCTCTG ATCCCACCTC ACCATTGAGA 
ACCAGATTTG TGTACCATTT GTCTGACCTC TGTAAAAAAT GTGATCCTAC AGAAGTGGAG 
CTGGATAATC AGATAGTTAC TGCTACCCAG AGCAATATCT GTGATGAAGA CAGTGCTACA 
GAGACCTGCT ACACTTATGA CAGAAACAAG TGCTACACAG CTGTGGTCCC ACTCGTATAT 
GGTGGTGAGA CCAAAATGGT GGAAACAGCC TTAACCCCAG ATGCCTGCTA TCCTGACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

JCHAIN ( XM_006714211.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_006714274.1 Homo sapiens immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides (IGJ), transcript variant X2, mRNA.

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CloneID	OHu13960
Clone ID Related Accession (Same CDS sequence)	XM_011531926.1 , XM_011531925.1 , XM_006714212.2 , XM_006714211.1 , NM_144646.4 , XM_006714211.2 , NM_144646.3
Accession Version	XM_006714211.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 480bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-03-11
Organism	Homo sapiens(Human)
Product	immunoglobulin J chain isoform X1
Comment

ATGAAGAACC ATTTGCTTTT CTGGGGAGTC CTGGCGGTTT TTATTAAGGC TGTTCATGTG 
AAAGCCCAAG AAGATGAAAG GATTGTTCTT GTTGACAACA AATGTAAGTG TGCCCGGATT 
ACTTCCAGGA TCATCCGTTC TTCCGAAGAT CCTAATGAGG ACATTGTGGA GAGAAACATC 
CGAATTATTG TTCCTCTGAA CAACAGGGAG AATATCTCTG ATCCCACCTC ACCATTGAGA 
ACCAGATTTG TGTACCATTT GTCTGACCTC TGTAAAAAAT GTGATCCTAC AGAAGTGGAG 
CTGGATAATC AGATAGTTAC TGCTACCCAG AGCAATATCT GTGATGAAGA CAGTGCTACA 
GAGACCTGCT ACACTTATGA CAGAAACAAG TGCTACACAG CTGTGGTCCC ACTCGTATAT 
GGTGGTGAGA CCAAAATGGT GGAAACAGCC TTAACCCCAG ATGCCTGCTA TCCTGACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006714274.1
Translation	MKNHLLFWGVLAVFIKAVHVKAQEDERIVLVDNKCKCARITSRIIRSSEDPNEDIVERNIRIIVPLNNRENISDPTSPLRTRFVYHLSDLCKKCDPTEVELDNQIVTATQSNICDEDSATETCYTYDRNKCYTAVVPLVYGGETKMVETALTPDACYPD

Target ORF information:

RefSeq Version	XM_006714211.1
Organism	Homo sapiens(Human)
Definition	Homo sapiens immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides (IGJ), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006714211.1

ORF Insert Sequence:

ATGAAGAACC ATTTGCTTTT CTGGGGAGTC CTGGCGGTTT TTATTAAGGC TGTTCATGTG 
AAAGCCCAAG AAGATGAAAG GATTGTTCTT GTTGACAACA AATGTAAGTG TGCCCGGATT 
ACTTCCAGGA TCATCCGTTC TTCCGAAGAT CCTAATGAGG ACATTGTGGA GAGAAACATC 
CGAATTATTG TTCCTCTGAA CAACAGGGAG AATATCTCTG ATCCCACCTC ACCATTGAGA 
ACCAGATTTG TGTACCATTT GTCTGACCTC TGTAAAAAAT GTGATCCTAC AGAAGTGGAG 
CTGGATAATC AGATAGTTAC TGCTACCCAG AGCAATATCT GTGATGAAGA CAGTGCTACA 
GAGACCTGCT ACACTTATGA CAGAAACAAG TGCTACACAG CTGTGGTCCC ACTCGTATAT 
GGTGGTGAGA CCAAAATGGT GGAAACAGCC TTAACCCCAG ATGCCTGCTA TCCTGACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

JCHAIN ( XM_006714211.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_006714274.1 Homo sapiens joining chain of multimeric IgA and IgM (JCHAIN), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu13960
Clone ID Related Accession (Same CDS sequence)	XM_011531926.1 , XM_011531925.1 , XM_006714212.2 , XM_006714211.1 , NM_144646.4 , XM_006714211.2 , NM_144646.3
Accession Version	XM_006714211.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 480bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	immunoglobulin J chain isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000004.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_006714211.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAAGAACC ATTTGCTTTT CTGGGGAGTC CTGGCGGTTT TTATTAAGGC TGTTCATGTG 
AAAGCCCAAG AAGATGAAAG GATTGTTCTT GTTGACAACA AATGTAAGTG TGCCCGGATT 
ACTTCCAGGA TCATCCGTTC TTCCGAAGAT CCTAATGAGG ACATTGTGGA GAGAAACATC 
CGAATTATTG TTCCTCTGAA CAACAGGGAG AATATCTCTG ATCCCACCTC ACCATTGAGA 
ACCAGATTTG TGTACCATTT GTCTGACCTC TGTAAAAAAT GTGATCCTAC AGAAGTGGAG 
CTGGATAATC AGATAGTTAC TGCTACCCAG AGCAATATCT GTGATGAAGA CAGTGCTACA 
GAGACCTGCT ACACTTATGA CAGAAACAAG TGCTACACAG CTGTGGTCCC ACTCGTATAT 
GGTGGTGAGA CCAAAATGGT GGAAACAGCC TTAACCCCAG ATGCCTGCTA TCCTGACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006714274.1
CDS	107..586
Translation	MKNHLLFWGVLAVFIKAVHVKAQEDERIVLVDNKCKCARITSRIIRSSEDPNEDIVERNIRIIVPLNNRENISDPTSPLRTRFVYHLSDLCKKCDPTEVELDNQIVTATQSNICDEDSATETCYTYDRNKCYTAVVPLVYGGETKMVETALTPDACYPD

Target ORF information:

RefSeq Version	XM_006714211.2
Organism	Homo sapiens(human)
Definition	Homo sapiens joining chain of multimeric IgA and IgM (JCHAIN), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006714211.2

ORF Insert Sequence:

ATGAAGAACC ATTTGCTTTT CTGGGGAGTC CTGGCGGTTT TTATTAAGGC TGTTCATGTG 
AAAGCCCAAG AAGATGAAAG GATTGTTCTT GTTGACAACA AATGTAAGTG TGCCCGGATT 
ACTTCCAGGA TCATCCGTTC TTCCGAAGAT CCTAATGAGG ACATTGTGGA GAGAAACATC 
CGAATTATTG TTCCTCTGAA CAACAGGGAG AATATCTCTG ATCCCACCTC ACCATTGAGA 
ACCAGATTTG TGTACCATTT GTCTGACCTC TGTAAAAAAT GTGATCCTAC AGAAGTGGAG 
CTGGATAATC AGATAGTTAC TGCTACCCAG AGCAATATCT GTGATGAAGA CAGTGCTACA 
GAGACCTGCT ACACTTATGA CAGAAACAAG TGCTACACAG CTGTGGTCCC ACTCGTATAT 
GGTGGTGAGA CCAAAATGGT GGAAACAGCC TTAACCCCAG ATGCCTGCTA TCCTGACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

High expression of ID family and IGJ genes signature as predictor of low induction treatment response and worst survival in adult Hispanic patients with B-acute lymphoblastic leukemia.
Journal of experimental & clinical cancer research : CR3564(2016 Apr)
Cruz-Rodriguez N,Combita AL,Enciso LJ,Quijano SM,Pinzon PL,Lozano OC,Castillo JS,Li L,Bare?o J,Cardozo C,Solano J,Herrera MV,Cudris J,Zabaleta J

Expression and glycoengineering of functionally active heteromultimeric IgM in plants.
Proceedings of the National Academy of Sciences of the United States of America111(17)6263-8(2014 Apr)
Loos A,Gruber C,Altmann F,Mehofer U,Hensel F,Grandits M,Oostenbrink C,Stadlmayr G,Furtm?ller PG,Steinkellner H

Characterization, quantification, and assessment of immune protection potential of secretory immunoglobulin A in colostrum samples from Saudi women.
Saudi medical journal34(10)1013-9(2013 Oct)
Almogren A

Shotgun proteomics reveals specific modulated protein patterns in tears of patients with primary open angle glaucoma na?ve to therapy.
Molecular bioSystems9(6)1108-16(2013 Jun)
Pieragostino D,Agnifili L,Fasanella V,D'Aguanno S,Mastropasqua R,Di Ilio C,Sacchetta P,Urbani A,Del Boccio P

Human J chain gene: chromosomal localization and associated restriction fragment length polymorphisms.
Proceedings of the National Academy of Sciences of the United States of America83(15)5592-6(1986 Aug)
Max EE,McBride OW,Morton CC,Robinson MA

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JCHAIN cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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