PRSS42 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	PRSS42
Entrez Gene ID	339906
Full Name	serine protease 42
Synonyms	TESSP2
General protein information	Preferred Names serine protease 42 Names serine protease 42 protease, serine 42 testis serine protease 2
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 3 Map Location: 3p21.31
Summary	This gene encodes a member of a family of testis-specific serine proteases that also includes PRSS41, PRSS43, and PRSS44. The orthologous mouse gene is expressed during meiosis in pachytene spermatocytes and is required for germ cell survival. [provided by RefSeq, Jul 2017]. COMPLETENESS: complete on the 3' end.

mRNA and Protein(s)

mRNA	Protein	Name
NM_182702.1	NP_874361.1	serine protease 42 precursor
NM_182702.2	NP_874361.1	serine protease 42 precursor

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Prss42	NP_694739.1
Homo sapiens (human)	PRSS42	NP_874361.1
Pan troglodytes (chimpanzee)	PRSS42	XP_526198.2
	LOC713075	XP_001102272.2
Canis lupus familiaris (dog)	PRSS42	XP_851584.3
Bos taurus (cattle)	PRSS42	NP_001108098.1
Rattus norvegicus (Norway rat)	Prss42	NP_001100333.2

Gene Ontology
Bibliography

Related articles in PubMed

Three testis-specific paralogous serine proteases play different roles in murine spermatogenesis and are involved in germ cell survival during meiosis.
Yoneda R, Takahashi T, Matsui H, Takano N, Hasebe Y, Ogiwara K, Kimura AP
Biology of reproduction88(5)118(2013 May)

Human and mouse proteases: a comparative genomic approach.
Puente XS, S?nchez LM, Overall CM, L?pez-Ot?n C
Nature reviews. Genetics4(7)544-58(2003 Jul)

Identification of 4370 expressed sequence tags from a 3'-end-specific cDNA library of human skeletal muscle by DNA sequencing and filter hybridization.
Lanfranchi G, Muraro T, Caldara F, Pacchioni B, Pallavicini A, Pandolfo D, Toppo S, Trevisan S, Scarso S, Valle G
Genome research6(1)35-42(1996 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following PRSS42 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the PRSS42 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu55702	NM_182702.2 Latest version!	Homo sapiens serine protease 42 (PRSS42), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$216.30 $309.00
View Old Accession Versions >>
OHu55702	NM_182702.1	Homo sapiens protease, serine 42 (PRSS42), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$216.30 $309.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

PRSS42 ( NM_182702.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_874361.1 Homo sapiens protease, serine 42 (PRSS42), mRNA.

Price & Availability↑

CloneID	OHu55702
Clone ID Related Accession (Same CDS sequence)	NM_182702.1 , NM_182702.2
Accession Version	NM_182702.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 882bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-08-25
Organism	Homo sapiens(Human)
Product	serine protease 42 precursor
Comment	PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AJ544583.1. ##Evidence-Data-START## Transcript exon combination :: AJ544583.1 [ECO:0000332] ##Evidence-Data-END##

ATGTCCTCTG GCGGCGGCTC CCGGGGCCTC CTGGCGTGGC TTCTGCTCCT TCAGCCCTGG 
CCCGGGCAGA ACTGGGCGGG CATGGCGGCG CCACGCCTCC CGTCCCCTCT CCTCTCAGAG 
GAGGGCGGCG AGAACCCCGA AGCGAGCCCG GCTCCAGGAC CTGAAGCGGG CCCCCCACTC 
AATCTGTTTA CGTCCTTTCC AGGTGACTCA CTGCTGTGTG GCCGAACCCC TCTGAGAATC 
GTGGGAGGAG TGGACGCGGA GGAAGGGAGG TGGCCCTGGC AGGTGAGCGT GAGGACCAAA 
GGCAGGCACA TCTGCGGCGG CACCCTGGTC ACCGCCACGT GGGTGCTGAC GGCAGGCCAC 
TGCATTTCCA GCCGTTTCCA TTACAGTGTC AAGATGGGAG ATCGGAGTGT CTATAATGAA 
AACACAAGTG TGGTGGTCTC AGTCCAAAGA GCTTTTGTCC ACCCTAAGTT CTCAACAGTT 
ACAACCATTC GAAATGACCT TGCCCTTCTC CAGCTCCAAC ATCCTGTGAA TTTTACCTCA 
AACATCCAGC CTATCTGCAT CCCTCAGGAG AATTTCCAGG TGGAAGGTAG GACCAGGTGC 
TGGGTGACCG GATGGGGCAA AACACCAGAA CGAGAGAAAC TTGCATCAGA AATTCTTCAG 
GATGTGGACC AATACATCAT GTGCTATGAG GAATGTAATA AGATAATACA GAAGGCCTTG 
TCATCTACTA AGGATGTAAT AATAAAAGGG ATGGTCTGTG GCTATAAAGA ACAAGGAAAG 
GATTCTTGTC AAGGAGATTC TGGGGGCCGC TTGGCCTGTG AATATAATGA CACATGGGTC 
CAGGTAGGGA TTGTGAGCTG GGGCATCGGC TGTGGTCGCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_874361.1
CDS	1..882
Translation	MSSGGGSRGLLAWLLLLQPWPGQNWAGMAAPRLPSPLLSEEGGENPEASPAPGPEAGPPLNLFTSFPGDSLLCGRTPLRIVGGVDAEEGRWPWQVSVRTKGRHICGGTLVTATWVLTAGHCISSRFHYSVKMGDRSVYNENTSVVVSVQRAFVHPKFSTVTTIRNDLALLQLQHPVNFTSNIQPICIPQENFQVEGRTRCWVTGWGKTPEREKLASEILQDVDQYIMCYEECNKIIQKALSSTKDVIIKGMVCGYKEQGKDSCQGDSGGRLACEYNDTWVQVGIVSWGIGCGR

Target ORF information:

RefSeq Version	NM_182702.1
Organism	Homo sapiens(Human)
Definition	Homo sapiens protease, serine 42 (PRSS42), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_182702.1

ORF Insert Sequence:

ATGTCCTCTG GCGGCGGCTC CCGGGGCCTC CTGGCGTGGC TTCTGCTCCT TCAGCCCTGG 
CCCGGGCAGA ACTGGGCGGG CATGGCGGCG CCACGCCTCC CGTCCCCTCT CCTCTCAGAG 
GAGGGCGGCG AGAACCCCGA AGCGAGCCCG GCTCCAGGAC CTGAAGCGGG CCCCCCACTC 
AATCTGTTTA CGTCCTTTCC AGGTGACTCA CTGCTGTGTG GCCGAACCCC TCTGAGAATC 
GTGGGAGGAG TGGACGCGGA GGAAGGGAGG TGGCCCTGGC AGGTGAGCGT GAGGACCAAA 
GGCAGGCACA TCTGCGGCGG CACCCTGGTC ACCGCCACGT GGGTGCTGAC GGCAGGCCAC 
TGCATTTCCA GCCGTTTCCA TTACAGTGTC AAGATGGGAG ATCGGAGTGT CTATAATGAA 
AACACAAGTG TGGTGGTCTC AGTCCAAAGA GCTTTTGTCC ACCCTAAGTT CTCAACAGTT 
ACAACCATTC GAAATGACCT TGCCCTTCTC CAGCTCCAAC ATCCTGTGAA TTTTACCTCA 
AACATCCAGC CTATCTGCAT CCCTCAGGAG AATTTCCAGG TGGAAGGTAG GACCAGGTGC 
TGGGTGACCG GATGGGGCAA AACACCAGAA CGAGAGAAAC TTGCATCAGA AATTCTTCAG 
GATGTGGACC AATACATCAT GTGCTATGAG GAATGTAATA AGATAATACA GAAGGCCTTG 
TCATCTACTA AGGATGTAAT AATAAAAGGG ATGGTCTGTG GCTATAAAGA ACAAGGAAAG 
GATTCTTGTC AAGGAGATTC TGGGGGCCGC TTGGCCTGTG AATATAATGA CACATGGGTC 
CAGGTAGGGA TTGTGAGCTG GGGCATCGGC TGTGGTCGCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PRSS42 ( NM_182702.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_874361.1 Homo sapiens serine protease 42 (PRSS42), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu55702
Clone ID Related Accession (Same CDS sequence)	NM_182702.1 , NM_182702.2
Accession Version	NM_182702.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 882bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-12-04
Organism	Homo sapiens(human)
Product	serine protease 42 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AJ544583.1, AK092703.1, AC109583.2 and F36354.1. On Jul 6, 2017 this sequence version replaced NM_182702.1. ##Evidence-Data-START## Transcript exon combination :: AJ544583.1 [ECO:0000332] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTCCTCTG GCGGCGGCTC CCGGGGCCTC CTGGCGTGGC TTCTGCTCCT TCAGCCCTGG 
CCCGGGCAGA ACTGGGCGGG CATGGCGGCG CCACGCCTCC CGTCCCCTCT CCTCTCAGAG 
GAGGGCGGCG AGAACCCCGA AGCGAGCCCG GCTCCAGGAC CTGAAGCGGG CCCCCCACTC 
AATCTGTTTA CGTCCTTTCC AGGTGACTCA CTGCTGTGTG GCCGAACCCC TCTGAGAATC 
GTGGGAGGAG TGGACGCGGA GGAAGGGAGG TGGCCCTGGC AGGTGAGCGT GAGGACCAAA 
GGCAGGCACA TCTGCGGCGG CACCCTGGTC ACCGCCACGT GGGTGCTGAC GGCAGGCCAC 
TGCATTTCCA GCCGTTTCCA TTACAGTGTC AAGATGGGAG ATCGGAGTGT CTATAATGAA 
AACACAAGTG TGGTGGTCTC AGTCCAAAGA GCTTTTGTCC ACCCTAAGTT CTCAACAGTT 
ACAACCATTC GAAATGACCT TGCCCTTCTC CAGCTCCAAC ATCCTGTGAA TTTTACCTCA 
AACATCCAGC CTATCTGCAT CCCTCAGGAG AATTTCCAGG TGGAAGGTAG GACCAGGTGC 
TGGGTGACCG GATGGGGCAA AACACCAGAA CGAGAGAAAC TTGCATCAGA AATTCTTCAG 
GATGTGGACC AATACATCAT GTGCTATGAG GAATGTAATA AGATAATACA GAAGGCCTTG 
TCATCTACTA AGGATGTAAT AATAAAAGGG ATGGTCTGTG GCTATAAAGA ACAAGGAAAG 
GATTCTTGTC AAGGAGATTC TGGGGGCCGC TTGGCCTGTG AATATAATGA CACATGGGTC 
CAGGTAGGGA TTGTGAGCTG GGGCATCGGC TGTGGTCGCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_874361.1
CDS	1..882
Translation	MSSGGGSRGLLAWLLLLQPWPGQNWAGMAAPRLPSPLLSEEGGENPEASPAPGPEAGPPLNLFTSFPGDSLLCGRTPLRIVGGVDAEEGRWPWQVSVRTKGRHICGGTLVTATWVLTAGHCISSRFHYSVKMGDRSVYNENTSVVVSVQRAFVHPKFSTVTTIRNDLALLQLQHPVNFTSNIQPICIPQENFQVEGRTRCWVTGWGKTPEREKLASEILQDVDQYIMCYEECNKIIQKALSSTKDVIIKGMVCGYKEQGKDSCQGDSGGRLACEYNDTWVQVGIVSWGIGCGR

Target ORF information:

RefSeq Version	NM_182702.2
Organism	Homo sapiens(human)
Definition	Homo sapiens serine protease 42 (PRSS42), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_182702.2

ORF Insert Sequence:

ATGTCCTCTG GCGGCGGCTC CCGGGGCCTC CTGGCGTGGC TTCTGCTCCT TCAGCCCTGG 
CCCGGGCAGA ACTGGGCGGG CATGGCGGCG CCACGCCTCC CGTCCCCTCT CCTCTCAGAG 
GAGGGCGGCG AGAACCCCGA AGCGAGCCCG GCTCCAGGAC CTGAAGCGGG CCCCCCACTC 
AATCTGTTTA CGTCCTTTCC AGGTGACTCA CTGCTGTGTG GCCGAACCCC TCTGAGAATC 
GTGGGAGGAG TGGACGCGGA GGAAGGGAGG TGGCCCTGGC AGGTGAGCGT GAGGACCAAA 
GGCAGGCACA TCTGCGGCGG CACCCTGGTC ACCGCCACGT GGGTGCTGAC GGCAGGCCAC 
TGCATTTCCA GCCGTTTCCA TTACAGTGTC AAGATGGGAG ATCGGAGTGT CTATAATGAA 
AACACAAGTG TGGTGGTCTC AGTCCAAAGA GCTTTTGTCC ACCCTAAGTT CTCAACAGTT 
ACAACCATTC GAAATGACCT TGCCCTTCTC CAGCTCCAAC ATCCTGTGAA TTTTACCTCA 
AACATCCAGC CTATCTGCAT CCCTCAGGAG AATTTCCAGG TGGAAGGTAG GACCAGGTGC 
TGGGTGACCG GATGGGGCAA AACACCAGAA CGAGAGAAAC TTGCATCAGA AATTCTTCAG 
GATGTGGACC AATACATCAT GTGCTATGAG GAATGTAATA AGATAATACA GAAGGCCTTG 
TCATCTACTA AGGATGTAAT AATAAAAGGG ATGGTCTGTG GCTATAAAGA ACAAGGAAAG 
GATTCTTGTC AAGGAGATTC TGGGGGCCGC TTGGCCTGTG AATATAATGA CACATGGGTC 
CAGGTAGGGA TTGTGAGCTG GGGCATCGGC TGTGGTCGCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Three testis-specific paralogous serine proteases play different roles in murine spermatogenesis and are involved in germ cell survival during meiosis.
Biology of reproduction88(5)118(2013 May)
Yoneda R,Takahashi T,Matsui H,Takano N,Hasebe Y,Ogiwara K,Kimura AP

Human and mouse proteases: a comparative genomic approach.
Nature reviews. Genetics4(7)544-58(2003 Jul)
Puente XS,S?nchez LM,Overall CM,L?pez-Ot?n C

Identification of 4370 expressed sequence tags from a 3'-end-specific cDNA library of human skeletal muscle by DNA sequencing and filter hybridization.
Genome research6(1)35-42(1996 Jan)
Lanfranchi G,Muraro T,Caldara F,Pacchioni B,Pallavicini A,Pandolfo D,Toppo S,Trevisan S,Scarso S,Valle G