HMOX1 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	HMOX1
Entrez Gene ID	3162
Full Name	heme oxygenase 1
Synonyms	HMOX1D,HO-1,HSP32,bK286B10
General protein information	Preferred Names heme oxygenase 1 Names heme oxygenase 1 heat shock protein, 32-kD heme oxygenase (decycling) 1
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 22 Map Location: 22q12.3
Summary	Heme oxygenase, an essential enzyme in heme catabolism, cleaves heme to form biliverdin, which is subsequently converted to bilirubin by biliverdin reductase, and carbon monoxide, a putative neurotransmitter. Heme oxygenase activity is induced by its substrate heme and by various nonheme substances. Heme oxygenase occurs as 2 isozymes, an inducible heme oxygenase-1 and a constitutive heme oxygenase-2. HMOX1 and HMOX2 belong to the heme oxygenase family. [provided by RefSeq, Jul 2008].
Disorder MIM:	141250
Disorder Html:	Heme oxygenase-1 deficiency, 614034 (3); {Pulmonary disease, chronic obstructive, susceptibility to}, 606963 (3)

mRNA and Protein(s)

mRNA	Protein	Name
NM_002133.2	NP_002124.1	heme oxygenase 1
NM_002133.3	NP_002124.1	heme oxygenase 1

Pathways from BioSystems

Homologies

Bos taurus (cattle)	HMOX1	NP_001014912.1
Mus musculus (house mouse)	Hmox1	NP_034572.1
Homo sapiens (human)	HMOX1	NP_002124.1
Rattus norvegicus (Norway rat)	Hmox1	NP_036712.1
Xenopus tropicalis (tropical clawed frog)	hmox1	XP_002934766.1
Pan troglodytes (chimpanzee)	HMOX1	XP_525579.2
Canis lupus familiaris (dog)	HMOX1	NP_001181898.1
	HMOX1	XP_001113241.2
Gallus gallus (chicken)	HMOX1	NP_990675.1
Danio rerio (zebrafish)	hmox1a	NP_001120988.1

Gene Ontology

The following HMOX1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the HMOX1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu27420	NM_002133.3 Latest version!	Homo sapiens heme oxygenase 1 (HMOX1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
View Old Accession Versions >>
OHu27420	NM_002133.2	Homo sapiens heme oxygenase 1 (HMOX1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

HMOX1 ( NM_002133.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_002124.1 Homo sapiens heme oxygenase 1 (HMOX1), mRNA.

Price & Availability↑

CloneID	OHu27420
Clone ID Related Accession (Same CDS sequence)	NM_002133.2 , NM_002133.3
Accession Version	NM_002133.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 867bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-12-28
Organism	Homo sapiens(human)
Product	heme oxygenase 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BP288767.1, X06985.1 and CA306357.1. This sequence is a reference standard in the RefSeqGene project. On Jun 19, 2010 this sequence version replaced NM_002133.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: ERR279846.3550.1, BC001491.2 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGAGCGTC CGCAACCCGA CAGCATGCCC CAGGATTTGT CAGAGGCCCT GAAGGAGGCC 
ACCAAGGAGG TGCACACCCA GGCAGAGAAT GCTGAGTTCA TGAGGAACTT TCAGAAGGGC 
CAGGTGACCC GAGACGGCTT CAAGCTGGTG ATGGCCTCCC TGTACCACAT CTATGTGGCC 
CTGGAGGAGG AGATTGAGCG CAACAAGGAG AGCCCAGTCT TCGCCCCTGT CTACTTCCCA 
GAAGAGCTGC ACCGCAAGGC TGCCCTGGAG CAGGACCTGG CCTTCTGGTA CGGGCCCCGC 
TGGCAGGAGG TCATCCCCTA CACACCAGCC ATGCAGCGCT ATGTGAAGCG GCTCCACGAG 
GTGGGGCGCA CAGAGCCCGA GCTGCTGGTG GCCCACGCCT ACACCCGCTA CCTGGGTGAC 
CTGTCTGGGG GCCAGGTGCT CAAAAAGATT GCCCAGAAAG CCCTGGACCT GCCCAGCTCT 
GGCGAGGGCC TGGCCTTCTT CACCTTCCCC AACATTGCCA GTGCCACCAA GTTCAAGCAG 
CTCTACCGCT CCCGCATGAA CTCCCTGGAG ATGACTCCCG CAGTCAGGCA GAGGGTGATA 
GAAGAGGCCA AGACTGCGTT CCTGCTCAAC ATCCAGCTCT TTGAGGAGTT GCAGGAGCTG 
CTGACCCATG ACACCAAGGA CCAGAGCCCC TCACGGGCAC CAGGGCTTCG CCAGCGGGCC 
AGCAACAAAG TGCAAGATTC TGCCCCCGTG GAGACTCCCA GAGGGAAGCC CCCACTCAAC 
ACCCGCTCCC AGGCTCCGCT TCTCCGATGG GTCCTTACAC TCAGCTTTCT GGTGGCGACA 
GTTGCTGTAG GGCTTTATGC CATGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_002124.1
CDS	108..974
Translation	MERPQPDSMPQDLSEALKEATKEVHTQAENAEFMRNFQKGQVTRDGFKLVMASLYHIYVALEEEIERNKESPVFAPVYFPEELHRKAALEQDLAFWYGPRWQEVIPYTPAMQRYVKRLHEVGRTEPELLVAHAYTRYLGDLSGGQVLKKIAQKALDLPSSGEGLAFFTFPNIASATKFKQLYRSRMNSLEMTPAVRQRVIEEAKTAFLLNIQLFEELQELLTHDTKDQSPSRAPGLRQRASNKVQDSAPVETPRGKPPLNTRSQAPLLRWVLTLSFLVATVAVGLYAM

Target ORF information:

RefSeq Version	NM_002133.2
Organism	Homo sapiens(human)
Definition	Homo sapiens heme oxygenase 1 (HMOX1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_002133.2

ORF Insert Sequence:

ATGGAGCGTC CGCAACCCGA CAGCATGCCC CAGGATTTGT CAGAGGCCCT GAAGGAGGCC 
ACCAAGGAGG TGCACACCCA GGCAGAGAAT GCTGAGTTCA TGAGGAACTT TCAGAAGGGC 
CAGGTGACCC GAGACGGCTT CAAGCTGGTG ATGGCCTCCC TGTACCACAT CTATGTGGCC 
CTGGAGGAGG AGATTGAGCG CAACAAGGAG AGCCCAGTCT TCGCCCCTGT CTACTTCCCA 
GAAGAGCTGC ACCGCAAGGC TGCCCTGGAG CAGGACCTGG CCTTCTGGTA CGGGCCCCGC 
TGGCAGGAGG TCATCCCCTA CACACCAGCC ATGCAGCGCT ATGTGAAGCG GCTCCACGAG 
GTGGGGCGCA CAGAGCCCGA GCTGCTGGTG GCCCACGCCT ACACCCGCTA CCTGGGTGAC 
CTGTCTGGGG GCCAGGTGCT CAAAAAGATT GCCCAGAAAG CCCTGGACCT GCCCAGCTCT 
GGCGAGGGCC TGGCCTTCTT CACCTTCCCC AACATTGCCA GTGCCACCAA GTTCAAGCAG 
CTCTACCGCT CCCGCATGAA CTCCCTGGAG ATGACTCCCG CAGTCAGGCA GAGGGTGATA 
GAAGAGGCCA AGACTGCGTT CCTGCTCAAC ATCCAGCTCT TTGAGGAGTT GCAGGAGCTG 
CTGACCCATG ACACCAAGGA CCAGAGCCCC TCACGGGCAC CAGGGCTTCG CCAGCGGGCC 
AGCAACAAAG TGCAAGATTC TGCCCCCGTG GAGACTCCCA GAGGGAAGCC CCCACTCAAC 
ACCCGCTCCC AGGCTCCGCT TCTCCGATGG GTCCTTACAC TCAGCTTTCT GGTGGCGACA 
GTTGCTGTAG GGCTTTATGC CATGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

HMOX1 ( NM_002133.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_002124.1 Homo sapiens heme oxygenase 1 (HMOX1), mRNA.

Price & Availability↑

CloneID	OHu27420
Clone ID Related Accession (Same CDS sequence)	NM_002133.2 , NM_002133.3
Accession Version	NM_002133.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 867bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-30
Organism	Homo sapiens(human)
Product	heme oxygenase 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BP288767.1, X06985.1 and CA306357.1. This sequence is a reference standard in the RefSeqGene project. On Nov 22, 2018 this sequence version replaced NM_002133.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR3476690.1099521.1, X06985.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000216117.9/ ENSP00000216117.8 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGAGCGTC CGCAACCCGA CAGCATGCCC CAGGATTTGT CAGAGGCCCT GAAGGAGGCC 
ACCAAGGAGG TGCACACCCA GGCAGAGAAT GCTGAGTTCA TGAGGAACTT TCAGAAGGGC 
CAGGTGACCC GAGACGGCTT CAAGCTGGTG ATGGCCTCCC TGTACCACAT CTATGTGGCC 
CTGGAGGAGG AGATTGAGCG CAACAAGGAG AGCCCAGTCT TCGCCCCTGT CTACTTCCCA 
GAAGAGCTGC ACCGCAAGGC TGCCCTGGAG CAGGACCTGG CCTTCTGGTA CGGGCCCCGC 
TGGCAGGAGG TCATCCCCTA CACACCAGCC ATGCAGCGCT ATGTGAAGCG GCTCCACGAG 
GTGGGGCGCA CAGAGCCCGA GCTGCTGGTG GCCCACGCCT ACACCCGCTA CCTGGGTGAC 
CTGTCTGGGG GCCAGGTGCT CAAAAAGATT GCCCAGAAAG CCCTGGACCT GCCCAGCTCT 
GGCGAGGGCC TGGCCTTCTT CACCTTCCCC AACATTGCCA GTGCCACCAA GTTCAAGCAG 
CTCTACCGCT CCCGCATGAA CTCCCTGGAG ATGACTCCCG CAGTCAGGCA GAGGGTGATA 
GAAGAGGCCA AGACTGCGTT CCTGCTCAAC ATCCAGCTCT TTGAGGAGTT GCAGGAGCTG 
CTGACCCATG ACACCAAGGA CCAGAGCCCC TCACGGGCAC CAGGGCTTCG CCAGCGGGCC 
AGCAACAAAG TGCAAGATTC TGCCCCCGTG GAGACTCCCA GAGGGAAGCC CCCACTCAAC 
ACCCGCTCCC AGGCTCCGCT TCTCCGATGG GTCCTTACAC TCAGCTTTCT GGTGGCGACA 
GTTGCTGTAG GGCTTTATGC CATGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_002124.1
CDS	79..945
Translation	MERPQPDSMPQDLSEALKEATKEVHTQAENAEFMRNFQKGQVTRDGFKLVMASLYHIYVALEEEIERNKESPVFAPVYFPEELHRKAALEQDLAFWYGPRWQEVIPYTPAMQRYVKRLHEVGRTEPELLVAHAYTRYLGDLSGGQVLKKIAQKALDLPSSGEGLAFFTFPNIASATKFKQLYRSRMNSLEMTPAVRQRVIEEAKTAFLLNIQLFEELQELLTHDTKDQSPSRAPGLRQRASNKVQDSAPVETPRGKPPLNTRSQAPLLRWVLTLSFLVATVAVGLYAM

Target ORF information:

RefSeq Version	NM_002133.3
Organism	Homo sapiens(human)
Definition	Homo sapiens heme oxygenase 1 (HMOX1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_002133.3

ORF Insert Sequence:

ATGGAGCGTC CGCAACCCGA CAGCATGCCC CAGGATTTGT CAGAGGCCCT GAAGGAGGCC 
ACCAAGGAGG TGCACACCCA GGCAGAGAAT GCTGAGTTCA TGAGGAACTT TCAGAAGGGC 
CAGGTGACCC GAGACGGCTT CAAGCTGGTG ATGGCCTCCC TGTACCACAT CTATGTGGCC 
CTGGAGGAGG AGATTGAGCG CAACAAGGAG AGCCCAGTCT TCGCCCCTGT CTACTTCCCA 
GAAGAGCTGC ACCGCAAGGC TGCCCTGGAG CAGGACCTGG CCTTCTGGTA CGGGCCCCGC 
TGGCAGGAGG TCATCCCCTA CACACCAGCC ATGCAGCGCT ATGTGAAGCG GCTCCACGAG 
GTGGGGCGCA CAGAGCCCGA GCTGCTGGTG GCCCACGCCT ACACCCGCTA CCTGGGTGAC 
CTGTCTGGGG GCCAGGTGCT CAAAAAGATT GCCCAGAAAG CCCTGGACCT GCCCAGCTCT 
GGCGAGGGCC TGGCCTTCTT CACCTTCCCC AACATTGCCA GTGCCACCAA GTTCAAGCAG 
CTCTACCGCT CCCGCATGAA CTCCCTGGAG ATGACTCCCG CAGTCAGGCA GAGGGTGATA 
GAAGAGGCCA AGACTGCGTT CCTGCTCAAC ATCCAGCTCT TTGAGGAGTT GCAGGAGCTG 
CTGACCCATG ACACCAAGGA CCAGAGCCCC TCACGGGCAC CAGGGCTTCG CCAGCGGGCC 
AGCAACAAAG TGCAAGATTC TGCCCCCGTG GAGACTCCCA GAGGGAAGCC CCCACTCAAC 
ACCCGCTCCC AGGCTCCGCT TCTCCGATGG GTCCTTACAC TCAGCTTTCT GGTGGCGACA 
GTTGCTGTAG GGCTTTATGC CATGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.