RBM15B cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	RBM15B
Entrez Gene ID	29890
Full Name	RNA binding motif protein 15B
Synonyms	HUMAGCGB,OTT3
General protein information	Preferred Names RNA binding motif protein 15B Names putative RNA-binding protein 15B chromosome 3p21.1 gene sequence huOTT3 one twenty two protein 3
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 3 Map Location: 3p21.2
Summary	Members of the SPEN (Split-end) family of proteins, including RBM15B, have repressor function in several signaling pathways and may bind to RNA through interaction with spliceosome components (Hiriart et al., 2005 [PubMed 16129689]).[supplied by OMIM, Feb 2009].
Disorder MIM:	612602

mRNA and Protein(s)

mRNA	Protein	Name
NM_013286.5	NP_037418.3	putative RNA-binding protein 15B
NM_013286.4	NP_037418.3	putative RNA-binding protein 15B

Pathways from BioSystems

Homologies

	RBM15B	XP_001096996.1
Rattus norvegicus (Norway rat)	Rbm15b	XP_006243925.1
Bos taurus (cattle)	RBM15B	NP_001193510.1
Mus musculus (house mouse)	Rbm15b	NP_780611.3
Gallus gallus (chicken)	MANF	XP_003642020.2
Xenopus tropicalis (tropical clawed frog)	rbm15b	XP_002935665.2
Homo sapiens (human)	RBM15B	NP_037418.3
Pan troglodytes (chimpanzee)	RBM15B	XP_516489.2
Canis lupus familiaris (dog)	RBM15B	XP_003639807.1

Gene Ontology
Bibliography

Related articles in PubMed

m(6)A RNA methylation promotes XIST-mediated transcriptional repression.
Patil DP, Chen CK, Pickering BF, Chow A, Jackson C, Guttman M, Jaffrey SR
Nature537(7620)369-373(2016 09)

Insights into RNA biology from an atlas of mammalian mRNA-binding proteins.
Castello A, Fischer B, Eichelbaum K, Horos R, Beckmann BM, Strein C, Davey NE, Humphreys DT, Preiss T, Steinmetz LM, Krijgsveld J, Hentze MW
Cell149(6)1393-406(2012 Jun)

The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.
Baltz AG, Munschauer M, Schwanh?usser B, Vasile A, Murakawa Y, Schueler M, Youngs N, Penfold-Brown D, Drew K, Milek M, Wyler E, Bonneau R, Selbach M, Dieterich C, Landthaler M
Molecular cell46(5)674-90(2012 Jun)

Kaposi's sarcoma-associated herpesvirus ORF57 interacts with cellular RNA export cofactors RBM15 and OTT3 to promote expression of viral ORF59.
Majerciak V, Uranishi H, Kruhlak M, Pilkington GR, Massimelli MJ, Bear J, Pavlakis GN, Felber BK, Zheng ZM
Journal of virology85(4)1528-40(2011 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

HHV-8 ORF57 interacts with RBM15 and OTT3 to promote expression of viral intronless genes.
Title: Kaposi's sarcoma-associated herpesvirus ORF57 interacts with cellular RNA export cofactors RBM15 and OTT3 to promote expression of viral ORF59.

The RNA-binding motif protein 15B (RBM15B/OTT3) acts as cofactor of the nuclear export receptor NXF1.
Title: The RNA-binding motif protein 15B (RBM15B/OTT3) acts as cofactor of the nuclear export receptor NXF1.

The following RBM15B gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the RBM15B cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu11045	NM_013286.5 Latest version!	Homo sapiens RNA binding motif protein 15B (RBM15B), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$629.30 $899.00
View Old Accession Versions >>
OHu11045	NM_013286.4	Homo sapiens RNA binding motif protein 15B (RBM15B), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$629.30 $899.00
Hide Old Accession Versions >>

ORF Online Only Promotion

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

RBM15B ( NM_013286.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_037418.3 Homo sapiens RNA binding motif protein 15B (RBM15B), mRNA.

Price & Availability↑

CloneID	OHu11045
Clone ID Related Accession (Same CDS sequence)	NM_013286.5 , NM_013286.4
Accession Version	NM_013286.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2673bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-04
Organism	Homo sapiens(human)
Product	putative RNA-binding protein 15B
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC092037.2 and BM980577.1. On Nov 22, 2018 this sequence version replaced NM_013286.4. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript is intronless :: SRR1163657.530463.1 [ECO:0000345] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000563281.2/ ENSP00000454545.1 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGAAGCGGC AGAGCGAGCG AGACTCTAGC CCGAGCGGGC GCGGCTCGTC ATCGTCCGCC 
AAGCGTCCGC GGGAGCGCGA ACGGGAGGCG GAGGCGGGCG GGCGGCGGGC GGCGCACAAG 
GCCTCTGGCG GCGCCAAGCA CCCGGTTCCA GCGCGGGCCC GCGACAAACC CCGCGGCAGC 
GGAAGCGGCG GGGGCGGGCA TCGCGACGGC CGCGGCACCG GGGACGCGAA TCACCGCGCG 
AGTAGCGGGC GCTCCTCGGG CTCCGGCGCT GGCGGCGGGG GACGCGGCGG CAAGGCCTCG 
GGGGACCCGG GCGCCTCCGG CATGTCGCCC CGCGCGTCTC CTCTGCCGCC GCCTCCGCCA 
CCGCCTGGGG CCGAGCCCGC GTGTCCCGGC TCATCCGCGG CCGCGCCTGA GTACAAGACG 
TTGCTCATCA GCAGCTTGAG CCCCGCGCTG CCCGCCGAGC ACCTCGAGGA CCGGCTCTTC 
CACCAGTTCA AGCGCTTCGG CGAGATCAGC CTCCGCCTGT CGCACACGCC TGAGCTGGGC 
CGTGTGGCCT ACGTGAATTT CCGGCACCCA CAGGACGCAC GCGAGGCCCG CCAGCACGCC 
CTGGCCCGGC AGCTGCTGCT CTACGACCGC CCGCTCAAGG TAGAGCCCGT GTACCTGCGT 
GGCGGCGGCG GGAGCAGTCG GCGAAGTAGC AGCAGCAGCG CCGCCGCTTC CACGCCTCCC 
CCAGGGCCGC CCGCGCCCGC CGACCCGCTC GGCTACCTCC CGCTACACGG AGGCTACCAG 
TACAAGCAGC GCTCGCTGTC CCCCGTCGCT GCCCCGCCCC TGCGGGAGCC CCGTGCCCGT 
CACGCCGCCG CAGCCTTCGC CCTGGATGCC GCTGCTGCCG CCGCCGTGGG ACTGTCCCGG 
GAGCGGGCCC TGGACTACTA CGGGCTGTAC GACGACCGTG GGCGCCCCTA TGGCTACCCA 
GCTGTGTGTG AGGAGGACCT GATGCCCGAG GATGACCAGC GGGCCACGCG CAACCTCTTC 
ATTGGTAACC TGGACCACAG CGTATCTGAG GTGGAGCTGC GAAGGGCCTT CGAGAAATAT 
GGCATCATCG AGGAGGTGGT CATCAAGAGG CCTGCCCGTG GCCAGGGCGG TGCCTATGCC 
TTCCTCAAGT TCCAGAACCT GGACATGGCC CATAGGGCTA AGGTGGCCAT GTCGGGCCGA 
GTGATTGGTC GCAACCCCAT TAAGATAGGC TATGGCAAGG CCAACCCCAC CACTCGTCTC 
TGGGTGGGTG GCCTGGGACC TAACACGTCA CTGGCGGCTC TGGCCCGAGA GTTTGACCGC 
TTTGGGAGCA TTCGGACCAT TGATCACGTC AAAGGAGATA GCTTTGCCTA TATTCAGTAC 
GAGAGCTTGG ACGCAGCCCA GGCCGCCTGT GCTAAAATGA GGGGTTTTCC CTTGGGTGGA 
CCAGACCGCA GGCTCCGCGT GGATTTTGCC AAAGCAGAGG AGACTCGGTA CCCCCAGCAG 
TACCAGCCCT CGCCACTCCC TGTGCATTAT GAGCTGCTCA CAGATGGATA CACCCGGCAC 
CGCAACCTGG ACGCCGACCT GGTGCGGGAC AGGACGCCCC CACACCTTCT GTACTCAGAC 
CGAGACCGGA CTTTTTTGGA AGGGGACTGG ACCAGCCCCA GTAAAAGCTC TGACCGCCGA 
AACAGCCTTG AGGGCTACAG TCGCTCAGTG CGCAGCCGGA GTGGTGAGCG TTGGGGGGCA 
GATGGAGACC GTGGTTTGCC CAAGCCCTGG GAAGAGAGGC GGAAACGGAG AAGCCTTTCC 
AGTGACCGTG GGAGGACAAC CCATTCACCA TATGAGGAAC GGAGTAGGAC CAAGGGCAGT 
GGGCAGCAGT CAGAGCGGGG CTCCGACCGC ACCCCTGAGC GCAGCCGCAA GGAGAACCAC 
TCCAGTGAAG GGACCAAGGA GTCCAGCAGC AACTCCCTCA GCAACAGCAG ACATGGGGCT 
GAGGAACGGG GCCACCACCA CCACCACCAC GAGGCTGCAG ACTCTTCCCA CGGGAAGAAG 
GCAAGAGACA GCGAGCGCAA TCACCGGACC ACAGAGGCCG AGCCCAAGCC TCTGGAAGAG 
CCAAAACACG AGACCAAAAA GCTGAAGAAT CTTTCAGAGT ACGCTCAGAC ACTACAGCTG 
GGTTGGAATG GGCTTCTGGT GTTGAAAAAC AGCTGCTTCC CCACGTCTAT GCATATCCTA 
GAGGGGGACC AGGGGGTGAT CAGCAGTCTC CTCAAAGACC ACACTTCTGG GAGCAAGCTG 
ACCCAGCTGA AGATCGCCCA GCGCCTTCGA CTGGACCAGC CCAAGCTTGA CGAGGTCACA 
CGACGCATCA AGCAGGGGAG CCCCAACGGC TATGCGGTCC TCTTAGCCAC CCAGGCAACC 
CCCAGTGGGC TTGGCACTGA GGGGATGCCC ACAGTAGAGC CCGGTCTGCA GAGGCGGCTT 
CTCAGGAACC TGGTCTCCTA CTTGAAACAG AAGCAGGCCG CAGGGGTGAT CAGCTTGCCA 
GTGGGGGGGT CCAAGGGCAG AGACGGCACA GGCATGCTCT ACGCCTTCCC ACCCTGCGAC 
TTTTCCCAGC AGTACCTCCA GTCAGCACTA AGGACATTGG GCAAGCTAGA AGAAGAACAC 
ATGGTGATAG TCATCGTCAG AGACACTGCC TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_037418.3
CDS	116..2788
Translation	MKRQSERDSSPSGRGSSSSAKRPREREREAEAGGRRAAHKASGGAKHPVPARARDKPRGSGSGGGGHRDGRGTGDANHRASSGRSSGSGAGGGGRGGKASGDPGASGMSPRASPLPPPPPPPGAEPACPGSSAAAPEYKTLLISSLSPALPAEHLEDRLFHQFKRFGEISLRLSHTPELGRVAYVNFRHPQDAREARQHALARQLLLYDRPLKVEPVYLRGGGGSSRRSSSSSAAASTPPPGPPAPADPLGYLPLHGGYQYKQRSLSPVAAPPLREPRARHAAAAFALDAAAAAAVGLSRERALDYYGLYDDRGRPYGYPAVCEEDLMPEDDQRATRNLFIGNLDHSVSEVELRRAFEKYGIIEEVVIKRPARGQGGAYAFLKFQNLDMAHRAKVAMSGRVIGRNPIKIGYGKANPTTRLWVGGLGPNTSLAALAREFDRFGSIRTIDHVKGDSFAYIQYESLDAAQAACAKMRGFPLGGPDRRLRVDFAKAEETRYPQQYQPSPLPVHYELLTDGYTRHRNLDADLVRDRTPPHLLYSDRDRTFLEGDWTSPSKSSDRRNSLEGYSRSVRSRSGERWGADGDRGLPKPWEERRKRRSLSSDRGRTTHSPYEERSRTKGSGQQSERGSDRTPERSRKENHSSEGTKESSSNSLSNSRHGAEERGHHHHHHEAADSSHGKKARDSERNHRTTEAEPKPLEEPKHETKKLKNLSEYAQTLQLGWNGLLVLKNSCFPTSMHILEGDQGVISSLLKDHTSGSKLTQLKIAQRLRLDQPKLDEVTRRIKQGSPNGYAVLLATQATPSGLGTEGMPTVEPGLQRRLLRNLVSYLKQKQAAGVISLPVGGSKGRDGTGMLYAFPPCDFSQQYLQSALRTLGKLEEEHMVIVIVRDTA

Target ORF information:

RefSeq Version	NM_013286.5
Organism	Homo sapiens(human)
Definition	Homo sapiens RNA binding motif protein 15B (RBM15B), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_013286.5

ORF Insert Sequence:

ATGAAGCGGC AGAGCGAGCG AGACTCTAGC CCGAGCGGGC GCGGCTCGTC ATCGTCCGCC 
AAGCGTCCGC GGGAGCGCGA ACGGGAGGCG GAGGCGGGCG GGCGGCGGGC GGCGCACAAG 
GCCTCTGGCG GCGCCAAGCA CCCGGTTCCA GCGCGGGCCC GCGACAAACC CCGCGGCAGC 
GGAAGCGGCG GGGGCGGGCA TCGCGACGGC CGCGGCACCG GGGACGCGAA TCACCGCGCG 
AGTAGCGGGC GCTCCTCGGG CTCCGGCGCT GGCGGCGGGG GACGCGGCGG CAAGGCCTCG 
GGGGACCCGG GCGCCTCCGG CATGTCGCCC CGCGCGTCTC CTCTGCCGCC GCCTCCGCCA 
CCGCCTGGGG CCGAGCCCGC GTGTCCCGGC TCATCCGCGG CCGCGCCTGA GTACAAGACG 
TTGCTCATCA GCAGCTTGAG CCCCGCGCTG CCCGCCGAGC ACCTCGAGGA CCGGCTCTTC 
CACCAGTTCA AGCGCTTCGG CGAGATCAGC CTCCGCCTGT CGCACACGCC TGAGCTGGGC 
CGTGTGGCCT ACGTGAATTT CCGGCACCCA CAGGACGCAC GCGAGGCCCG CCAGCACGCC 
CTGGCCCGGC AGCTGCTGCT CTACGACCGC CCGCTCAAGG TAGAGCCCGT GTACCTGCGT 
GGCGGCGGCG GGAGCAGTCG GCGAAGTAGC AGCAGCAGCG CCGCCGCTTC CACGCCTCCC 
CCAGGGCCGC CCGCGCCCGC CGACCCGCTC GGCTACCTCC CGCTACACGG AGGCTACCAG 
TACAAGCAGC GCTCGCTGTC CCCCGTCGCT GCCCCGCCCC TGCGGGAGCC CCGTGCCCGT 
CACGCCGCCG CAGCCTTCGC CCTGGATGCC GCTGCTGCCG CCGCCGTGGG ACTGTCCCGG 
GAGCGGGCCC TGGACTACTA CGGGCTGTAC GACGACCGTG GGCGCCCCTA TGGCTACCCA 
GCTGTGTGTG AGGAGGACCT GATGCCCGAG GATGACCAGC GGGCCACGCG CAACCTCTTC 
ATTGGTAACC TGGACCACAG CGTATCTGAG GTGGAGCTGC GAAGGGCCTT CGAGAAATAT 
GGCATCATCG AGGAGGTGGT CATCAAGAGG CCTGCCCGTG GCCAGGGCGG TGCCTATGCC 
TTCCTCAAGT TCCAGAACCT GGACATGGCC CATAGGGCTA AGGTGGCCAT GTCGGGCCGA 
GTGATTGGTC GCAACCCCAT TAAGATAGGC TATGGCAAGG CCAACCCCAC CACTCGTCTC 
TGGGTGGGTG GCCTGGGACC TAACACGTCA CTGGCGGCTC TGGCCCGAGA GTTTGACCGC 
TTTGGGAGCA TTCGGACCAT TGATCACGTC AAAGGAGATA GCTTTGCCTA TATTCAGTAC 
GAGAGCTTGG ACGCAGCCCA GGCCGCCTGT GCTAAAATGA GGGGTTTTCC CTTGGGTGGA 
CCAGACCGCA GGCTCCGCGT GGATTTTGCC AAAGCAGAGG AGACTCGGTA CCCCCAGCAG 
TACCAGCCCT CGCCACTCCC TGTGCATTAT GAGCTGCTCA CAGATGGATA CACCCGGCAC 
CGCAACCTGG ACGCCGACCT GGTGCGGGAC AGGACGCCCC CACACCTTCT GTACTCAGAC 
CGAGACCGGA CTTTTTTGGA AGGGGACTGG ACCAGCCCCA GTAAAAGCTC TGACCGCCGA 
AACAGCCTTG AGGGCTACAG TCGCTCAGTG CGCAGCCGGA GTGGTGAGCG TTGGGGGGCA 
GATGGAGACC GTGGTTTGCC CAAGCCCTGG GAAGAGAGGC GGAAACGGAG AAGCCTTTCC 
AGTGACCGTG GGAGGACAAC CCATTCACCA TATGAGGAAC GGAGTAGGAC CAAGGGCAGT 
GGGCAGCAGT CAGAGCGGGG CTCCGACCGC ACCCCTGAGC GCAGCCGCAA GGAGAACCAC 
TCCAGTGAAG GGACCAAGGA GTCCAGCAGC AACTCCCTCA GCAACAGCAG ACATGGGGCT 
GAGGAACGGG GCCACCACCA CCACCACCAC GAGGCTGCAG ACTCTTCCCA CGGGAAGAAG 
GCAAGAGACA GCGAGCGCAA TCACCGGACC ACAGAGGCCG AGCCCAAGCC TCTGGAAGAG 
CCAAAACACG AGACCAAAAA GCTGAAGAAT CTTTCAGAGT ACGCTCAGAC ACTACAGCTG 
GGTTGGAATG GGCTTCTGGT GTTGAAAAAC AGCTGCTTCC CCACGTCTAT GCATATCCTA 
GAGGGGGACC AGGGGGTGAT CAGCAGTCTC CTCAAAGACC ACACTTCTGG GAGCAAGCTG 
ACCCAGCTGA AGATCGCCCA GCGCCTTCGA CTGGACCAGC CCAAGCTTGA CGAGGTCACA 
CGACGCATCA AGCAGGGGAG CCCCAACGGC TATGCGGTCC TCTTAGCCAC CCAGGCAACC 
CCCAGTGGGC TTGGCACTGA GGGGATGCCC ACAGTAGAGC CCGGTCTGCA GAGGCGGCTT 
CTCAGGAACC TGGTCTCCTA CTTGAAACAG AAGCAGGCCG CAGGGGTGAT CAGCTTGCCA 
GTGGGGGGGT CCAAGGGCAG AGACGGCACA GGCATGCTCT ACGCCTTCCC ACCCTGCGAC 
TTTTCCCAGC AGTACCTCCA GTCAGCACTA AGGACATTGG GCAAGCTAGA AGAAGAACAC 
ATGGTGATAG TCATCGTCAG AGACACTGCC TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RBM15B ( NM_013286.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_037418.3 Homo sapiens RNA binding motif protein 15B (RBM15B), mRNA.

Price & Availability↑

CloneID	OHu11045
Clone ID Related Accession (Same CDS sequence)	NM_013286.5 , NM_013286.4
Accession Version	NM_013286.4	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2673bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Homo sapiens(human)
Product	putative RNA-binding protein 15B
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC092037.2 and BM980577.1. On Dec 27, 2010 this sequence version replaced NM_013286.3. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. COMPLETENESS: complete on the 3' end.

ATGAAGCGGC AGAGCGAGCG AGACTCTAGC CCGAGCGGGC GCGGCTCGTC ATCGTCCGCC 
AAGCGTCCGC GGGAGCGCGA ACGGGAGGCG GAGGCGGGCG GGCGGCGGGC GGCGCACAAG 
GCCTCTGGCG GCGCCAAGCA CCCGGTTCCA GCGCGGGCCC GCGACAAACC CCGCGGCAGC 
GGAAGCGGCG GGGGCGGGCA TCGCGACGGC CGCGGCACCG GGGACGCGAA TCACCGCGCG 
AGTAGCGGGC GCTCCTCGGG CTCCGGCGCT GGCGGCGGGG GACGCGGCGG CAAGGCCTCG 
GGGGACCCGG GCGCCTCCGG CATGTCGCCC CGCGCGTCTC CTCTGCCGCC GCCTCCGCCA 
CCGCCTGGGG CCGAGCCCGC GTGTCCCGGC TCATCCGCGG CCGCGCCTGA GTACAAGACG 
TTGCTCATCA GCAGCTTGAG CCCCGCGCTG CCCGCCGAGC ACCTCGAGGA CCGGCTCTTC 
CACCAGTTCA AGCGCTTCGG CGAGATCAGC CTCCGCCTGT CGCACACGCC TGAGCTGGGC 
CGTGTGGCCT ACGTGAATTT CCGGCACCCA CAGGACGCAC GCGAGGCCCG CCAGCACGCC 
CTGGCCCGGC AGCTGCTGCT CTACGACCGC CCGCTCAAGG TAGAGCCCGT GTACCTGCGT 
GGCGGCGGCG GGAGCAGTCG GCGAAGTAGC AGCAGCAGCG CCGCCGCTTC CACGCCTCCC 
CCAGGGCCGC CCGCGCCCGC CGACCCGCTC GGCTACCTCC CGCTACACGG AGGCTACCAG 
TACAAGCAGC GCTCGCTGTC CCCCGTCGCT GCCCCGCCCC TGCGGGAGCC CCGTGCCCGT 
CACGCCGCCG CAGCCTTCGC CCTGGATGCC GCTGCTGCCG CCGCCGTGGG ACTGTCCCGG 
GAGCGGGCCC TGGACTACTA CGGGCTGTAC GACGACCGTG GGCGCCCCTA TGGCTACCCA 
GCTGTGTGTG AGGAGGACCT GATGCCCGAG GATGACCAGC GGGCCACGCG CAACCTCTTC 
ATTGGTAACC TGGACCACAG CGTATCTGAG GTGGAGCTGC GAAGGGCCTT CGAGAAATAT 
GGCATCATCG AGGAGGTGGT CATCAAGAGG CCTGCCCGTG GCCAGGGCGG TGCCTATGCC 
TTCCTCAAGT TCCAGAACCT GGACATGGCC CATAGGGCTA AGGTGGCCAT GTCGGGCCGA 
GTGATTGGTC GCAACCCCAT TAAGATAGGC TATGGCAAGG CCAACCCCAC CACTCGTCTC 
TGGGTGGGTG GCCTGGGACC TAACACGTCA CTGGCGGCTC TGGCCCGAGA GTTTGACCGC 
TTTGGGAGCA TTCGGACCAT TGATCACGTC AAAGGAGATA GCTTTGCCTA TATTCAGTAC 
GAGAGCTTGG ACGCAGCCCA GGCCGCCTGT GCTAAAATGA GGGGTTTTCC CTTGGGTGGA 
CCAGACCGCA GGCTCCGCGT GGATTTTGCC AAAGCAGAGG AGACTCGGTA CCCCCAGCAG 
TACCAGCCCT CGCCACTCCC TGTGCATTAT GAGCTGCTCA CAGATGGATA CACCCGGCAC 
CGCAACCTGG ACGCCGACCT GGTGCGGGAC AGGACGCCCC CACACCTTCT GTACTCAGAC 
CGAGACCGGA CTTTTTTGGA AGGGGACTGG ACCAGCCCCA GTAAAAGCTC TGACCGCCGA 
AACAGCCTTG AGGGCTACAG TCGCTCAGTG CGCAGCCGGA GTGGTGAGCG TTGGGGGGCA 
GATGGAGACC GTGGTTTGCC CAAGCCCTGG GAAGAGAGGC GGAAACGGAG AAGCCTTTCC 
AGTGACCGTG GGAGGACAAC CCATTCACCA TATGAGGAAC GGAGTAGGAC CAAGGGCAGT 
GGGCAGCAGT CAGAGCGGGG CTCCGACCGC ACCCCTGAGC GCAGCCGCAA GGAGAACCAC 
TCCAGTGAAG GGACCAAGGA GTCCAGCAGC AACTCCCTCA GCAACAGCAG ACATGGGGCT 
GAGGAACGGG GCCACCACCA CCACCACCAC GAGGCTGCAG ACTCTTCCCA CGGGAAGAAG 
GCAAGAGACA GCGAGCGCAA TCACCGGACC ACAGAGGCCG AGCCCAAGCC TCTGGAAGAG 
CCAAAACACG AGACCAAAAA GCTGAAGAAT CTTTCAGAGT ACGCTCAGAC ACTACAGCTG 
GGTTGGAATG GGCTTCTGGT GTTGAAAAAC AGCTGCTTCC CCACGTCTAT GCATATCCTA 
GAGGGGGACC AGGGGGTGAT CAGCAGTCTC CTCAAAGACC ACACTTCTGG GAGCAAGCTG 
ACCCAGCTGA AGATCGCCCA GCGCCTTCGA CTGGACCAGC CCAAGCTTGA CGAGGTCACA 
CGACGCATCA AGCAGGGGAG CCCCAACGGC TATGCGGTCC TCTTAGCCAC CCAGGCAACC 
CCCAGTGGGC TTGGCACTGA GGGGATGCCC ACAGTAGAGC CCGGTCTGCA GAGGCGGCTT 
CTCAGGAACC TGGTCTCCTA CTTGAAACAG AAGCAGGCCG CAGGGGTGAT CAGCTTGCCA 
GTGGGGGGGT CCAAGGGCAG AGACGGCACA GGCATGCTCT ACGCCTTCCC ACCCTGCGAC 
TTTTCCCAGC AGTACCTCCA GTCAGCACTA AGGACATTGG GCAAGCTAGA AGAAGAACAC 
ATGGTGATAG TCATCGTCAG AGACACTGCC TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_037418.3
CDS	133..2805
Translation	MKRQSERDSSPSGRGSSSSAKRPREREREAEAGGRRAAHKASGGAKHPVPARARDKPRGSGSGGGGHRDGRGTGDANHRASSGRSSGSGAGGGGRGGKASGDPGASGMSPRASPLPPPPPPPGAEPACPGSSAAAPEYKTLLISSLSPALPAEHLEDRLFHQFKRFGEISLRLSHTPELGRVAYVNFRHPQDAREARQHALARQLLLYDRPLKVEPVYLRGGGGSSRRSSSSSAAASTPPPGPPAPADPLGYLPLHGGYQYKQRSLSPVAAPPLREPRARHAAAAFALDAAAAAAVGLSRERALDYYGLYDDRGRPYGYPAVCEEDLMPEDDQRATRNLFIGNLDHSVSEVELRRAFEKYGIIEEVVIKRPARGQGGAYAFLKFQNLDMAHRAKVAMSGRVIGRNPIKIGYGKANPTTRLWVGGLGPNTSLAALAREFDRFGSIRTIDHVKGDSFAYIQYESLDAAQAACAKMRGFPLGGPDRRLRVDFAKAEETRYPQQYQPSPLPVHYELLTDGYTRHRNLDADLVRDRTPPHLLYSDRDRTFLEGDWTSPSKSSDRRNSLEGYSRSVRSRSGERWGADGDRGLPKPWEERRKRRSLSSDRGRTTHSPYEERSRTKGSGQQSERGSDRTPERSRKENHSSEGTKESSSNSLSNSRHGAEERGHHHHHHEAADSSHGKKARDSERNHRTTEAEPKPLEEPKHETKKLKNLSEYAQTLQLGWNGLLVLKNSCFPTSMHILEGDQGVISSLLKDHTSGSKLTQLKIAQRLRLDQPKLDEVTRRIKQGSPNGYAVLLATQATPSGLGTEGMPTVEPGLQRRLLRNLVSYLKQKQAAGVISLPVGGSKGRDGTGMLYAFPPCDFSQQYLQSALRTLGKLEEEHMVIVIVRDTA

Target ORF information:

RefSeq Version	NM_013286.4
Organism	Homo sapiens(human)
Definition	Homo sapiens RNA binding motif protein 15B (RBM15B), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_013286.4

ORF Insert Sequence:

ATGAAGCGGC AGAGCGAGCG AGACTCTAGC CCGAGCGGGC GCGGCTCGTC ATCGTCCGCC 
AAGCGTCCGC GGGAGCGCGA ACGGGAGGCG GAGGCGGGCG GGCGGCGGGC GGCGCACAAG 
GCCTCTGGCG GCGCCAAGCA CCCGGTTCCA GCGCGGGCCC GCGACAAACC CCGCGGCAGC 
GGAAGCGGCG GGGGCGGGCA TCGCGACGGC CGCGGCACCG GGGACGCGAA TCACCGCGCG 
AGTAGCGGGC GCTCCTCGGG CTCCGGCGCT GGCGGCGGGG GACGCGGCGG CAAGGCCTCG 
GGGGACCCGG GCGCCTCCGG CATGTCGCCC CGCGCGTCTC CTCTGCCGCC GCCTCCGCCA 
CCGCCTGGGG CCGAGCCCGC GTGTCCCGGC TCATCCGCGG CCGCGCCTGA GTACAAGACG 
TTGCTCATCA GCAGCTTGAG CCCCGCGCTG CCCGCCGAGC ACCTCGAGGA CCGGCTCTTC 
CACCAGTTCA AGCGCTTCGG CGAGATCAGC CTCCGCCTGT CGCACACGCC TGAGCTGGGC 
CGTGTGGCCT ACGTGAATTT CCGGCACCCA CAGGACGCAC GCGAGGCCCG CCAGCACGCC 
CTGGCCCGGC AGCTGCTGCT CTACGACCGC CCGCTCAAGG TAGAGCCCGT GTACCTGCGT 
GGCGGCGGCG GGAGCAGTCG GCGAAGTAGC AGCAGCAGCG CCGCCGCTTC CACGCCTCCC 
CCAGGGCCGC CCGCGCCCGC CGACCCGCTC GGCTACCTCC CGCTACACGG AGGCTACCAG 
TACAAGCAGC GCTCGCTGTC CCCCGTCGCT GCCCCGCCCC TGCGGGAGCC CCGTGCCCGT 
CACGCCGCCG CAGCCTTCGC CCTGGATGCC GCTGCTGCCG CCGCCGTGGG ACTGTCCCGG 
GAGCGGGCCC TGGACTACTA CGGGCTGTAC GACGACCGTG GGCGCCCCTA TGGCTACCCA 
GCTGTGTGTG AGGAGGACCT GATGCCCGAG GATGACCAGC GGGCCACGCG CAACCTCTTC 
ATTGGTAACC TGGACCACAG CGTATCTGAG GTGGAGCTGC GAAGGGCCTT CGAGAAATAT 
GGCATCATCG AGGAGGTGGT CATCAAGAGG CCTGCCCGTG GCCAGGGCGG TGCCTATGCC 
TTCCTCAAGT TCCAGAACCT GGACATGGCC CATAGGGCTA AGGTGGCCAT GTCGGGCCGA 
GTGATTGGTC GCAACCCCAT TAAGATAGGC TATGGCAAGG CCAACCCCAC CACTCGTCTC 
TGGGTGGGTG GCCTGGGACC TAACACGTCA CTGGCGGCTC TGGCCCGAGA GTTTGACCGC 
TTTGGGAGCA TTCGGACCAT TGATCACGTC AAAGGAGATA GCTTTGCCTA TATTCAGTAC 
GAGAGCTTGG ACGCAGCCCA GGCCGCCTGT GCTAAAATGA GGGGTTTTCC CTTGGGTGGA 
CCAGACCGCA GGCTCCGCGT GGATTTTGCC AAAGCAGAGG AGACTCGGTA CCCCCAGCAG 
TACCAGCCCT CGCCACTCCC TGTGCATTAT GAGCTGCTCA CAGATGGATA CACCCGGCAC 
CGCAACCTGG ACGCCGACCT GGTGCGGGAC AGGACGCCCC CACACCTTCT GTACTCAGAC 
CGAGACCGGA CTTTTTTGGA AGGGGACTGG ACCAGCCCCA GTAAAAGCTC TGACCGCCGA 
AACAGCCTTG AGGGCTACAG TCGCTCAGTG CGCAGCCGGA GTGGTGAGCG TTGGGGGGCA 
GATGGAGACC GTGGTTTGCC CAAGCCCTGG GAAGAGAGGC GGAAACGGAG AAGCCTTTCC 
AGTGACCGTG GGAGGACAAC CCATTCACCA TATGAGGAAC GGAGTAGGAC CAAGGGCAGT 
GGGCAGCAGT CAGAGCGGGG CTCCGACCGC ACCCCTGAGC GCAGCCGCAA GGAGAACCAC 
TCCAGTGAAG GGACCAAGGA GTCCAGCAGC AACTCCCTCA GCAACAGCAG ACATGGGGCT 
GAGGAACGGG GCCACCACCA CCACCACCAC GAGGCTGCAG ACTCTTCCCA CGGGAAGAAG 
GCAAGAGACA GCGAGCGCAA TCACCGGACC ACAGAGGCCG AGCCCAAGCC TCTGGAAGAG 
CCAAAACACG AGACCAAAAA GCTGAAGAAT CTTTCAGAGT ACGCTCAGAC ACTACAGCTG 
GGTTGGAATG GGCTTCTGGT GTTGAAAAAC AGCTGCTTCC CCACGTCTAT GCATATCCTA 
GAGGGGGACC AGGGGGTGAT CAGCAGTCTC CTCAAAGACC ACACTTCTGG GAGCAAGCTG 
ACCCAGCTGA AGATCGCCCA GCGCCTTCGA CTGGACCAGC CCAAGCTTGA CGAGGTCACA 
CGACGCATCA AGCAGGGGAG CCCCAACGGC TATGCGGTCC TCTTAGCCAC CCAGGCAACC 
CCCAGTGGGC TTGGCACTGA GGGGATGCCC ACAGTAGAGC CCGGTCTGCA GAGGCGGCTT 
CTCAGGAACC TGGTCTCCTA CTTGAAACAG AAGCAGGCCG CAGGGGTGAT CAGCTTGCCA 
GTGGGGGGGT CCAAGGGCAG AGACGGCACA GGCATGCTCT ACGCCTTCCC ACCCTGCGAC 
TTTTCCCAGC AGTACCTCCA GTCAGCACTA AGGACATTGG GCAAGCTAGA AGAAGAACAC 
ATGGTGATAG TCATCGTCAG AGACACTGCC TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

m(6)A RNA methylation promotes XIST-mediated transcriptional repression.
Nature537(7620)369-373(2016 09)
Patil DP,Chen CK,Pickering BF,Chow A,Jackson C,Guttman M,Jaffrey SR

Insights into RNA biology from an atlas of mammalian mRNA-binding proteins.
Cell149(6)1393-406(2012 Jun)
Castello A,Fischer B,Eichelbaum K,Horos R,Beckmann BM,Strein C,Davey NE,Humphreys DT,Preiss T,Steinmetz LM,Krijgsveld J,Hentze MW

The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.
Molecular cell46(5)674-90(2012 Jun)
Baltz AG,Munschauer M,Schwanh?usser B,Vasile A,Murakawa Y,Schueler M,Youngs N,Penfold-Brown D,Drew K,Milek M,Wyler E,Bonneau R,Selbach M,Dieterich C,Landthaler M

Kaposi's sarcoma-associated herpesvirus ORF57 interacts with cellular RNA export cofactors RBM15 and OTT3 to promote expression of viral ORF59.
Journal of virology85(4)1528-40(2011 Feb)
Majerciak V,Uranishi H,Kruhlak M,Pilkington GR,Massimelli MJ,Bear J,Pavlakis GN,Felber BK,Zheng ZM