KLHL34 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	KLHL34
Entrez Gene ID	257240
Full Name	kelch like family member 34
General protein information	Preferred Names kelch like family member 34 Names kelch-like protein 34 RP11-450P7.3 kelch-like 34
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: X Map Location: Xp22.12

mRNA and Protein(s)

mRNA	Protein	Name
NM_153270.2	NP_695002.1	kelch-like protein 34
NM_153270.3	NP_695002.1	kelch-like protein 34

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	KLHL34	XP_529234.3
	KLHL34	XP_001086668.1
Canis lupus familiaris (dog)	KLHL34	XP_005642130.1
Rattus norvegicus (Norway rat)	Klhl34	XP_228962.2
Danio rerio (zebrafish)	LOC561692	XP_005162828.1
Xenopus tropicalis (tropical clawed frog)	klhl34	XP_002936091.1
Homo sapiens (human)	KLHL34	NP_695002.1
Gallus gallus (chicken)	KLHL34	XP_004934726.1
Mus musculus (house mouse)	Klhl34	NP_001075136.1
Bos taurus (cattle)	KLHL34	XP_005228440.1

Gene Ontology
Bibliography

Related articles in PubMed

Update on the Kelch-like (KLHL) gene family.
Dhanoa BS, Cogliati T, Satish AG, Bruford EA, Friedman JS
Human genomics713(2013 May)

Comparison of tear protein levels in breast cancer patients and healthy controls using a de novo proteomic approach.
B?hm D, Keller K, Pieter J, Boehm N, Wolters D, Siggelkow W, Lebrecht A, Schmidt M, K?lbl H, Pfeiffer N, Grus FH
Oncology reports28(2)429-38(2012 Aug)

The DNA sequence of the human X chromosome.
Ross MT, Grafham DV, Coffey AJ, Scherer S, McLay K, Muzny D, Platzer M, Howell GR, Burrows C, Bird CP, Frankish A, Lovell FL, Howe KL, Ashurst JL, Fulton RS, Sudbrak R, Wen G, Jones MC, Hurles ME, Andrews TD, Scott CE, Searle S, Ramser J, Whittaker A, Deadman R, Carter NP, Hunt SE, Chen R, Cree A, Gunaratne P, Havlak P, Hodgson A, Metzker ML, Richards S, Scott G, Steffen D, Sodergren E, Wheeler DA, Worley KC, Ainscough R, Ambrose KD, Ansari-Lari MA, Aradhya S, Ashwell RI, Babbage AK, Bagguley CL, Ballabio A, Banerjee R, Barker GE, Barlow KF, Barrett IP, Bates KN, Beare DM, Beasley H, Beasley O, Beck A, Bethel G, Blechschmidt K, Brady N, Bray-Allen S, Bridgeman AM, Brown AJ, Brown MJ, Bonnin D, Bruford EA, Buhay C, Burch P, Burford D, Burgess J, Burrill W, Burton J, Bye JM, Carder C, Carrel L, Chako J, Chapman JC, Chavez D, Chen E, Chen G, Chen Y, Chen Z, Chinault C, Ciccodicola A, Clark SY, Clarke G, Clee CM, Clegg S, Clerc-Blankenburg K, Clifford K, Cobley V, Cole CG, Conquer JS, Corby N, Connor RE, David R, Davies J, Davis C, Davis J, Delgado O, Deshazo D, Dhami P, Ding Y, Dinh H, Dodsworth S, Draper H, Dugan-Rocha S, Dunham A, Dunn M, Durbin KJ, Dutta I, Eades T, Ellwood M, Emery-Cohen A, Errington H, Evans KL, Faulkner L, Francis F, Frankland J, Fraser AE, Galgoczy P, Gilbert J, Gill R, Gl?ckner G, Gregory SG, Gribble S, Griffiths C, Grocock R, Gu Y, Gwilliam R, Hamilton C, Hart EA, Hawes A, Heath PD, Heitmann K, Hennig S, Hernandez J, Hinzmann B, Ho S, Hoffs M, Howden PJ, Huckle EJ, Hume J, Hunt PJ, Hunt AR, Isherwood J, Jacob L, Johnson D, Jones S, de Jong PJ, Joseph SS, Keenan S, Kelly S, Kershaw JK, Khan Z, Kioschis P, Klages S, Knights AJ, Kosiura A, Kovar-Smith C, Laird GK, Langford C, Lawlor S, Leversha M, Lewis L, Liu W, Lloyd C, Lloyd DM, Loulseged H, Loveland JE, Lovell JD, Lozado R, Lu J, Lyne R, Ma J, Maheshwari M, Matthews LH, McDowall J, McLaren S, McMurray A, Meidl P, Meitinger T, Milne S, Miner G, Mistry SL, Morgan M, Morris S, M?ller I, Mullikin JC, Nguyen N, Nordsiek G, Nyakatura G, O'Dell CN, Okwuonu G, Palmer S, Pandian R, Parker D, Parrish J, Pasternak S, Patel D, Pearce AV, Pearson DM, Pelan SE, Perez L, Porter KM, Ramsey Y, Reichwald K, Rhodes S, Ridler KA, Schlessinger D, Schueler MG, Sehra HK, Shaw-Smith C, Shen H, Sheridan EM, Shownkeen R, Skuce CD, Smith ML, Sotheran EC, Steingruber HE, Steward CA, Storey R, Swann RM, Swarbreck D, Tabor PE, Taudien S, Taylor T, Teague B, Thomas K, Thorpe A, Timms K, Tracey A, Trevanion S, Tromans AC, d'Urso M, Verduzco D, Villasana D, Waldron L, Wall M, Wang Q, Warren J, Warry GL, Wei X, West A, Whitehead SL, Whiteley MN, Wilkinson JE, Willey DL, Williams G, Williams L, Williamson A, Williamson H, Wilming L, Woodmansey RL, Wray PW, Yen J, Zhang J, Zhou J, Zoghbi H, Zorilla S, Buck D, Reinhardt R, Poustka A, Rosenthal A, Lehrach H, Meindl A, Minx PJ, Hillier LW, Willard HF, Wilson RK, Waterston RH, Rice CM, Vaudin M, Coulson A, Nelson DL, Weinstock G, Sulston JE, Durbin R, Hubbard T, Gibbs RA, Beck S, Rogers J, Bentley DR
Nature434(7031)325-37(2005 Mar)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following KLHL34 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the KLHL34 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu78461	NM_153270.3 Latest version!	Homo sapiens kelch like family member 34 (KLHL34), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
View Old Accession Versions >>
OHu78461	NM_153270.2	Homo sapiens kelch like family member 34 (KLHL34), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

KLHL34 ( NM_153270.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_695002.1 Homo sapiens kelch like family member 34 (KLHL34), mRNA.

Price & Availability↑

CloneID	OHu78461
Clone ID Related Accession (Same CDS sequence)	NM_153270.2 , NM_153270.3
Accession Version	NM_153270.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1935bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-06-29
Organism	Homo sapiens(human)
Product	kelch-like protein 34
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DA395149.1, BC109031.2 and AI792176.1. On Dec 25, 2014 this sequence version replaced NM_153270.1.

ATGAGTTACT TCCTGTCTTA CTGCAAAGCT CATGGCGGCG CGCTGCTCAC CGGCTACCAG 
GCCCTGCGCG CCGAGGGCTT CCTGTGCGAC GTGACACTGG AGACCGAGGG CAGCGAATTC 
CCGGCGCACA GGTCGCTCCT GGCGTGCTCC AGTGACTACT TCAGGGCCCT GTTCAAGAGC 
CACACCCAGG AATCCCGGGC GCGCGTGATC CACCTGCACG TGCCATCGGC AGCCGGCCTG 
CAGCGCCTGC TGGACTTCAT CTACACTGCC TGGCTGTCGC TTTCCATGGA CACTGTAGAG 
GACACTCTGG AGGCCGCCAG CTACCTGCAG GTCACTGAGG CCCTGGGGCT CTGTGGGCGC 
TACTTGGAGC GCCAGCTGGC TCCAGAGAAC TGCTGCTTCG CCGCCAACGT GGCAGCGCGC 
TTTGGCCTGG CTCACACGCT GGACGCGGCC GAGCGCTGCA TCGTGAGCCA CTTGCAGGAG 
CTGCTGGCGC GGGGCGCGGG CCCCGCGGGA CTCCTGGAGC TCAACCCTAC ATCGCTGAGG 
GCTGTACTGG GTGCCCCCGA CGTGGCGCGG GTGCCCGAGG CCCGGCTACT GGGCCTGGCG 
TTAGCTTGGT TGCGGCAGGA GCCCACAACT GAGCGCCTGG CACACTGTAC AGAGTTGCTG 
GAGCGTGTCC GCTTTGGCCT GGTTCCCGCC GACGTACTGC GGCGCGTGTA CTCGGGCTCT 
GGCCTCGTGC TGCCCGCCCG GGTCAAGGGC CTCATCATCC AGGCCCTCAA CTACCACACG 
ACGCCCTCCC GCCAGCCGCT CATGCAGGGC GAGCAGACCA GCATCCGGAG CCCCCAGACC 
CGCATCTTGT TGGTGGGGGG GCGCAGGGCA CGGGAGGTGG TGATTGAGGA GGTCGCGGCC 
CCGCAGAGGG CAGCTAGGGG CCAGGTCGCC GCCCCAGAGC CCGAGGAAGA AGAGGAAGAG 
TTGGAGGAAG AGGAGGAGGA GGAGGAGTGG GAGCTCACCC AGAACGTGGT GGCCTTCGAT 
GTGTACAATC ACCGCTGGCG CAGCCTTACG CAGCTACCCA CACCACTGCT GGGGCACAGC 
GTGTGCACCG CGGGCAACTT CCTGTTTGTC CTGGGTGGGG AGAGCCCTTC CGGCAGTGCA 
TCCTCTCCCC TGGCCGACGA CTCGCGGGTG GTCACGGCCC AAGTGCACCG TTACGACCCG 
CGCTTCCACG CTTGGACGGA AGTGCCCGCC ATGCGGGAAG CGCGGGCCCA CTTCTGGTGC 
GGCGCGGTGG GCGAGAGGCT CCTGGCCGTC GGGGGCCTGG GTGCGGGCGG TGAGGTGCTG 
GCCTCGGTGG AGATGTACGA CCTGCGTCGG GACCGCTGGA CGGCGGCTGG GGCACTACCG 
CGGGCTCTGC ACGGTCACGC GGGGGCCGTC GGGGACCGCG GTGTTGTGTA CATCTCGGGG 
GGCAAGGCAG GGAGAGGCGA GGGCGGAGCG AGCAGCCTCC GGGACTTATA CGTCCTGGGC 
CCTGAGGAGC AGGTTTGGAG CAAGAAGGCA CCCATGGGCA CCGCACGTTT CGGGCACCAC 
ATGGCAGTGC TGCGCGGCGC TGTGTTTGCT TTTCTGGGGC GATACGAGCC CTTCTCTGAG 
ATCGAGCGCT ACGACCCCGG CGCCGACCAG TGGACTCGGT TGCGGCCGCT GCCCTACGAC 
CGCTTCTGCT ATGGGCTGGC CGTGGTCGAG GAGACAGCGT TGCTGCTGGG CGGCCTCAAG 
TGGCGGGACT CGCGCCAGGT GCCTACCCGC AACGTAGTGG GCTACGACCT CGACCTGGAC 
CGTTGGGAGG ACATCGGCTG CGCGTTGCCC TGGGCCTGGA GCGGCCTGCG GTGCGCAGTG 
CTGCAGCTGG CCGAGGGTGG GGACGACGAG AGGGAGGGAG AGGTTGGAGA GGCGCTAGAT 
TTGGTGCTGG GCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_695002.1
CDS	600..2534
Translation	MSYFLSYCKAHGGALLTGYQALRAEGFLCDVTLETEGSEFPAHRSLLACSSDYFRALFKSHTQESRARVIHLHVPSAAGLQRLLDFIYTAWLSLSMDTVEDTLEAASYLQVTEALGLCGRYLERQLAPENCCFAANVAARFGLAHTLDAAERCIVSHLQELLARGAGPAGLLELNPTSLRAVLGAPDVARVPEARLLGLALAWLRQEPTTERLAHCTELLERVRFGLVPADVLRRVYSGSGLVLPARVKGLIIQALNYHTTPSRQPLMQGEQTSIRSPQTRILLVGGRRAREVVIEEVAAPQRAARGQVAAPEPEEEEEELEEEEEEEEWELTQNVVAFDVYNHRWRSLTQLPTPLLGHSVCTAGNFLFVLGGESPSGSASSPLADDSRVVTAQVHRYDPRFHAWTEVPAMREARAHFWCGAVGERLLAVGGLGAGGEVLASVEMYDLRRDRWTAAGALPRALHGHAGAVGDRGVVYISGGKAGRGEGGASSLRDLYVLGPEEQVWSKKAPMGTARFGHHMAVLRGAVFAFLGRYEPFSEIERYDPGADQWTRLRPLPYDRFCYGLAVVEETALLLGGLKWRDSRQVPTRNVVGYDLDLDRWEDIGCALPWAWSGLRCAVLQLAEGGDDEREGEVGEALDLVLG

Target ORF information:

RefSeq Version	NM_153270.2
Organism	Homo sapiens(human)
Definition	Homo sapiens kelch like family member 34 (KLHL34), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_153270.2

ORF Insert Sequence:

ATGAGTTACT TCCTGTCTTA CTGCAAAGCT CATGGCGGCG CGCTGCTCAC CGGCTACCAG 
GCCCTGCGCG CCGAGGGCTT CCTGTGCGAC GTGACACTGG AGACCGAGGG CAGCGAATTC 
CCGGCGCACA GGTCGCTCCT GGCGTGCTCC AGTGACTACT TCAGGGCCCT GTTCAAGAGC 
CACACCCAGG AATCCCGGGC GCGCGTGATC CACCTGCACG TGCCATCGGC AGCCGGCCTG 
CAGCGCCTGC TGGACTTCAT CTACACTGCC TGGCTGTCGC TTTCCATGGA CACTGTAGAG 
GACACTCTGG AGGCCGCCAG CTACCTGCAG GTCACTGAGG CCCTGGGGCT CTGTGGGCGC 
TACTTGGAGC GCCAGCTGGC TCCAGAGAAC TGCTGCTTCG CCGCCAACGT GGCAGCGCGC 
TTTGGCCTGG CTCACACGCT GGACGCGGCC GAGCGCTGCA TCGTGAGCCA CTTGCAGGAG 
CTGCTGGCGC GGGGCGCGGG CCCCGCGGGA CTCCTGGAGC TCAACCCTAC ATCGCTGAGG 
GCTGTACTGG GTGCCCCCGA CGTGGCGCGG GTGCCCGAGG CCCGGCTACT GGGCCTGGCG 
TTAGCTTGGT TGCGGCAGGA GCCCACAACT GAGCGCCTGG CACACTGTAC AGAGTTGCTG 
GAGCGTGTCC GCTTTGGCCT GGTTCCCGCC GACGTACTGC GGCGCGTGTA CTCGGGCTCT 
GGCCTCGTGC TGCCCGCCCG GGTCAAGGGC CTCATCATCC AGGCCCTCAA CTACCACACG 
ACGCCCTCCC GCCAGCCGCT CATGCAGGGC GAGCAGACCA GCATCCGGAG CCCCCAGACC 
CGCATCTTGT TGGTGGGGGG GCGCAGGGCA CGGGAGGTGG TGATTGAGGA GGTCGCGGCC 
CCGCAGAGGG CAGCTAGGGG CCAGGTCGCC GCCCCAGAGC CCGAGGAAGA AGAGGAAGAG 
TTGGAGGAAG AGGAGGAGGA GGAGGAGTGG GAGCTCACCC AGAACGTGGT GGCCTTCGAT 
GTGTACAATC ACCGCTGGCG CAGCCTTACG CAGCTACCCA CACCACTGCT GGGGCACAGC 
GTGTGCACCG CGGGCAACTT CCTGTTTGTC CTGGGTGGGG AGAGCCCTTC CGGCAGTGCA 
TCCTCTCCCC TGGCCGACGA CTCGCGGGTG GTCACGGCCC AAGTGCACCG TTACGACCCG 
CGCTTCCACG CTTGGACGGA AGTGCCCGCC ATGCGGGAAG CGCGGGCCCA CTTCTGGTGC 
GGCGCGGTGG GCGAGAGGCT CCTGGCCGTC GGGGGCCTGG GTGCGGGCGG TGAGGTGCTG 
GCCTCGGTGG AGATGTACGA CCTGCGTCGG GACCGCTGGA CGGCGGCTGG GGCACTACCG 
CGGGCTCTGC ACGGTCACGC GGGGGCCGTC GGGGACCGCG GTGTTGTGTA CATCTCGGGG 
GGCAAGGCAG GGAGAGGCGA GGGCGGAGCG AGCAGCCTCC GGGACTTATA CGTCCTGGGC 
CCTGAGGAGC AGGTTTGGAG CAAGAAGGCA CCCATGGGCA CCGCACGTTT CGGGCACCAC 
ATGGCAGTGC TGCGCGGCGC TGTGTTTGCT TTTCTGGGGC GATACGAGCC CTTCTCTGAG 
ATCGAGCGCT ACGACCCCGG CGCCGACCAG TGGACTCGGT TGCGGCCGCT GCCCTACGAC 
CGCTTCTGCT ATGGGCTGGC CGTGGTCGAG GAGACAGCGT TGCTGCTGGG CGGCCTCAAG 
TGGCGGGACT CGCGCCAGGT GCCTACCCGC AACGTAGTGG GCTACGACCT CGACCTGGAC 
CGTTGGGAGG ACATCGGCTG CGCGTTGCCC TGGGCCTGGA GCGGCCTGCG GTGCGCAGTG 
CTGCAGCTGG CCGAGGGTGG GGACGACGAG AGGGAGGGAG AGGTTGGAGA GGCGCTAGAT 
TTGGTGCTGG GCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

KLHL34 ( NM_153270.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_695002.1 Homo sapiens kelch like family member 34 (KLHL34), mRNA.

Price & Availability↑

CloneID	OHu78461
Clone ID Related Accession (Same CDS sequence)	NM_153270.2 , NM_153270.3
Accession Version	NM_153270.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1935bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-06-29
Organism	Homo sapiens(human)
Product	kelch-like protein 34
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DA395149.1, BC109031.2, AI792176.1 and AL772392.4. On May 17, 2019 this sequence version replaced NM_153270.2. ##Evidence-Data-START## Transcript is intronless :: AK092279.1, BC109031.2 [ECO:0000345] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000379499.3/ ENSP00000368813.2 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END##

ATGAGTTACT TCCTGTCTTA CTGCAAAGCT CATGGCGGCG CGCTGCTCAC CGGCTACCAG 
GCCCTGCGCG CCGAGGGCTT CCTGTGCGAC GTGACACTGG AGACCGAGGG CAGCGAATTC 
CCGGCGCACA GGTCGCTCCT GGCGTGCTCC AGTGACTACT TCAGGGCCCT GTTCAAGAGC 
CACACCCAGG AATCCCGGGC GCGCGTGATC CACCTGCACG TGCCATCGGC AGCCGGCCTG 
CAGCGCCTGC TGGACTTCAT CTACACTGCC TGGCTGTCGC TTTCCATGGA CACTGTAGAG 
GACACTCTGG AGGCCGCCAG CTACCTGCAG GTCACTGAGG CCCTGGGGCT CTGTGGGCGC 
TACTTGGAGC GCCAGCTGGC TCCAGAGAAC TGCTGCTTCG CCGCCAACGT GGCAGCGCGC 
TTTGGCCTGG CTCACACGCT GGACGCGGCC GAGCGCTGCA TCGTGAGCCA CTTGCAGGAG 
CTGCTGGCGC GGGGCGCGGG CCCCGCGGGA CTCCTGGAGC TCAACCCTAC ATCGCTGAGG 
GCTGTACTGG GTGCCCCCGA CGTGGCGCGG GTGCCCGAGG CCCGGCTACT GGGCCTGGCG 
TTAGCTTGGT TGCGGCAGGA GCCCACAACT GAGCGCCTGG CACACTGTAC AGAGTTGCTG 
GAGCGTGTCC GCTTTGGCCT GGTTCCCGCC GACGTACTGC GGCGCGTGTA CTCGGGCTCT 
GGCCTCGTGC TGCCCGCCCG GGTCAAGGGC CTCATCATCC AGGCCCTCAA CTACCACACG 
ACGCCCTCCC GCCAGCCGCT CATGCAGGGC GAGCAGACCA GCATCCGGAG CCCCCAGACC 
CGCATCTTGT TGGTGGGGGG GCGCAGGGCA CGGGAGGTGG TGATTGAGGA GGTCGCGGCC 
CCGCAGAGGG CAGCTAGGGG CCAGGTCGCC GCCCCAGAGC CCGAGGAAGA AGAGGAAGAG 
TTGGAGGAAG AGGAGGAGGA GGAGGAGTGG GAGCTCACCC AGAACGTGGT GGCCTTCGAT 
GTGTACAATC ACCGCTGGCG CAGCCTTACG CAGCTACCCA CACCACTGCT GGGGCACAGC 
GTGTGCACCG CGGGCAACTT CCTGTTTGTC CTGGGTGGGG AGAGCCCTTC CGGCAGTGCA 
TCCTCTCCCC TGGCCGACGA CTCGCGGGTG GTCACGGCCC AAGTGCACCG TTACGACCCG 
CGCTTCCACG CTTGGACGGA AGTGCCCGCC ATGCGGGAAG CGCGGGCCCA CTTCTGGTGC 
GGCGCGGTGG GCGAGAGGCT CCTGGCCGTC GGGGGCCTGG GTGCGGGCGG TGAGGTGCTG 
GCCTCGGTGG AGATGTACGA CCTGCGTCGG GACCGCTGGA CGGCGGCTGG GGCACTACCG 
CGGGCTCTGC ACGGTCACGC GGGGGCCGTC GGGGACCGCG GTGTTGTGTA CATCTCGGGG 
GGCAAGGCAG GGAGAGGCGA GGGCGGAGCG AGCAGCCTCC GGGACTTATA CGTCCTGGGC 
CCTGAGGAGC AGGTTTGGAG CAAGAAGGCA CCCATGGGCA CCGCACGTTT CGGGCACCAC 
ATGGCAGTGC TGCGCGGCGC TGTGTTTGCT TTTCTGGGGC GATACGAGCC CTTCTCTGAG 
ATCGAGCGCT ACGACCCCGG CGCCGACCAG TGGACTCGGT TGCGGCCGCT GCCCTACGAC 
CGCTTCTGCT ATGGGCTGGC CGTGGTCGAG GAGACAGCGT TGCTGCTGGG CGGCCTCAAG 
TGGCGGGACT CGCGCCAGGT GCCTACCCGC AACGTAGTGG GCTACGACCT CGACCTGGAC 
CGTTGGGAGG ACATCGGCTG CGCGTTGCCC TGGGCCTGGA GCGGCCTGCG GTGCGCAGTG 
CTGCAGCTGG CCGAGGGTGG GGACGACGAG AGGGAGGGAG AGGTTGGAGA GGCGCTAGAT 
TTGGTGCTGG GCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_695002.1
CDS	543..2477
Translation	MSYFLSYCKAHGGALLTGYQALRAEGFLCDVTLETEGSEFPAHRSLLACSSDYFRALFKSHTQESRARVIHLHVPSAAGLQRLLDFIYTAWLSLSMDTVEDTLEAASYLQVTEALGLCGRYLERQLAPENCCFAANVAARFGLAHTLDAAERCIVSHLQELLARGAGPAGLLELNPTSLRAVLGAPDVARVPEARLLGLALAWLRQEPTTERLAHCTELLERVRFGLVPADVLRRVYSGSGLVLPARVKGLIIQALNYHTTPSRQPLMQGEQTSIRSPQTRILLVGGRRAREVVIEEVAAPQRAARGQVAAPEPEEEEEELEEEEEEEEWELTQNVVAFDVYNHRWRSLTQLPTPLLGHSVCTAGNFLFVLGGESPSGSASSPLADDSRVVTAQVHRYDPRFHAWTEVPAMREARAHFWCGAVGERLLAVGGLGAGGEVLASVEMYDLRRDRWTAAGALPRALHGHAGAVGDRGVVYISGGKAGRGEGGASSLRDLYVLGPEEQVWSKKAPMGTARFGHHMAVLRGAVFAFLGRYEPFSEIERYDPGADQWTRLRPLPYDRFCYGLAVVEETALLLGGLKWRDSRQVPTRNVVGYDLDLDRWEDIGCALPWAWSGLRCAVLQLAEGGDDEREGEVGEALDLVLG

Target ORF information:

RefSeq Version	NM_153270.3
Organism	Homo sapiens(human)
Definition	Homo sapiens kelch like family member 34 (KLHL34), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_153270.3

ORF Insert Sequence:

ATGAGTTACT TCCTGTCTTA CTGCAAAGCT CATGGCGGCG CGCTGCTCAC CGGCTACCAG 
GCCCTGCGCG CCGAGGGCTT CCTGTGCGAC GTGACACTGG AGACCGAGGG CAGCGAATTC 
CCGGCGCACA GGTCGCTCCT GGCGTGCTCC AGTGACTACT TCAGGGCCCT GTTCAAGAGC 
CACACCCAGG AATCCCGGGC GCGCGTGATC CACCTGCACG TGCCATCGGC AGCCGGCCTG 
CAGCGCCTGC TGGACTTCAT CTACACTGCC TGGCTGTCGC TTTCCATGGA CACTGTAGAG 
GACACTCTGG AGGCCGCCAG CTACCTGCAG GTCACTGAGG CCCTGGGGCT CTGTGGGCGC 
TACTTGGAGC GCCAGCTGGC TCCAGAGAAC TGCTGCTTCG CCGCCAACGT GGCAGCGCGC 
TTTGGCCTGG CTCACACGCT GGACGCGGCC GAGCGCTGCA TCGTGAGCCA CTTGCAGGAG 
CTGCTGGCGC GGGGCGCGGG CCCCGCGGGA CTCCTGGAGC TCAACCCTAC ATCGCTGAGG 
GCTGTACTGG GTGCCCCCGA CGTGGCGCGG GTGCCCGAGG CCCGGCTACT GGGCCTGGCG 
TTAGCTTGGT TGCGGCAGGA GCCCACAACT GAGCGCCTGG CACACTGTAC AGAGTTGCTG 
GAGCGTGTCC GCTTTGGCCT GGTTCCCGCC GACGTACTGC GGCGCGTGTA CTCGGGCTCT 
GGCCTCGTGC TGCCCGCCCG GGTCAAGGGC CTCATCATCC AGGCCCTCAA CTACCACACG 
ACGCCCTCCC GCCAGCCGCT CATGCAGGGC GAGCAGACCA GCATCCGGAG CCCCCAGACC 
CGCATCTTGT TGGTGGGGGG GCGCAGGGCA CGGGAGGTGG TGATTGAGGA GGTCGCGGCC 
CCGCAGAGGG CAGCTAGGGG CCAGGTCGCC GCCCCAGAGC CCGAGGAAGA AGAGGAAGAG 
TTGGAGGAAG AGGAGGAGGA GGAGGAGTGG GAGCTCACCC AGAACGTGGT GGCCTTCGAT 
GTGTACAATC ACCGCTGGCG CAGCCTTACG CAGCTACCCA CACCACTGCT GGGGCACAGC 
GTGTGCACCG CGGGCAACTT CCTGTTTGTC CTGGGTGGGG AGAGCCCTTC CGGCAGTGCA 
TCCTCTCCCC TGGCCGACGA CTCGCGGGTG GTCACGGCCC AAGTGCACCG TTACGACCCG 
CGCTTCCACG CTTGGACGGA AGTGCCCGCC ATGCGGGAAG CGCGGGCCCA CTTCTGGTGC 
GGCGCGGTGG GCGAGAGGCT CCTGGCCGTC GGGGGCCTGG GTGCGGGCGG TGAGGTGCTG 
GCCTCGGTGG AGATGTACGA CCTGCGTCGG GACCGCTGGA CGGCGGCTGG GGCACTACCG 
CGGGCTCTGC ACGGTCACGC GGGGGCCGTC GGGGACCGCG GTGTTGTGTA CATCTCGGGG 
GGCAAGGCAG GGAGAGGCGA GGGCGGAGCG AGCAGCCTCC GGGACTTATA CGTCCTGGGC 
CCTGAGGAGC AGGTTTGGAG CAAGAAGGCA CCCATGGGCA CCGCACGTTT CGGGCACCAC 
ATGGCAGTGC TGCGCGGCGC TGTGTTTGCT TTTCTGGGGC GATACGAGCC CTTCTCTGAG 
ATCGAGCGCT ACGACCCCGG CGCCGACCAG TGGACTCGGT TGCGGCCGCT GCCCTACGAC 
CGCTTCTGCT ATGGGCTGGC CGTGGTCGAG GAGACAGCGT TGCTGCTGGG CGGCCTCAAG 
TGGCGGGACT CGCGCCAGGT GCCTACCCGC AACGTAGTGG GCTACGACCT CGACCTGGAC 
CGTTGGGAGG ACATCGGCTG CGCGTTGCCC TGGGCCTGGA GCGGCCTGCG GTGCGCAGTG 
CTGCAGCTGG CCGAGGGTGG GGACGACGAG AGGGAGGGAG AGGTTGGAGA GGCGCTAGAT 
TTGGTGCTGG GCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Update on the Kelch-like (KLHL) gene family.
Human genomics713(2013 May)
Dhanoa BS,Cogliati T,Satish AG,Bruford EA,Friedman JS

Comparison of tear protein levels in breast cancer patients and healthy controls using a de novo proteomic approach.
Oncology reports28(2)429-38(2012 Aug)
B?hm D,Keller K,Pieter J,Boehm N,Wolters D,Siggelkow W,Lebrecht A,Schmidt M,K?lbl H,Pfeiffer N,Grus FH

The DNA sequence of the human X chromosome.
Nature434(7031)325-37(2005 Mar)
Ross MT,Grafham DV,Coffey AJ,Scherer S,McLay K,Muzny D,Platzer M,Howell GR,Burrows C,Bird CP,Frankish A,Lovell FL,Howe KL,Ashurst JL,Fulton RS,Sudbrak R,Wen G,Jones MC,Hurles ME,Andrews TD,Scott CE,Searle S,Ramser J,Whittaker A,Deadman R,Carter NP,Hunt SE,Chen R,Cree A,Gunaratne P,Havlak P,Hodgson A,Metzker ML,Richards S,Scott G,Steffen D,Sodergren E,Wheeler DA,Worley KC,Ainscough R,Ambrose KD,Ansari-Lari MA,Aradhya S,Ashwell RI,Babbage AK,Bagguley CL,Ballabio A,Banerjee R,Barker GE,Barlow KF,Barrett IP,Bates KN,Beare DM,Beasley H,Beasley O,Beck A,Bethel G,Blechschmidt K,Brady N,Bray-Allen S,Bridgeman AM,Brown AJ,Brown MJ,Bonnin D,Bruford EA,Buhay C,Burch P,Burford D,Burgess J,Burrill W,Burton J,Bye JM,Carder C,Carrel L,Chako J,Chapman JC,Chavez D,Chen E,Chen G,Chen Y,Chen Z,Chinault C,Ciccodicola A,Clark SY,Clarke G,Clee CM,Clegg S,Clerc-Blankenburg K,Clifford K,Cobley V,Cole CG,Conquer JS,Corby N,Connor RE,David R,Davies J,Davis C,Davis J,Delgado O,Deshazo D,Dhami P,Ding Y,Dinh H,Dodsworth S,Draper H,Dugan-Rocha S,Dunham A,Dunn M,Durbin KJ,Dutta I,Eades T,Ellwood M,Emery-Cohen A,Errington H,Evans KL,Faulkner L,Francis F,Frankland J,Fraser AE,Galgoczy P,Gilbert J,Gill R,Gl?ckner G,Gregory SG,Gribble S,Griffiths C,Grocock R,Gu Y,Gwilliam R,Hamilton C,Hart EA,Hawes A,Heath PD,Heitmann K,Hennig S,Hernandez J,Hinzmann B,Ho S,Hoffs M,Howden PJ,Huckle EJ,Hume J,Hunt PJ,Hunt AR,Isherwood J,Jacob L,Johnson D,Jones S,de Jong PJ,Joseph SS,Keenan S,Kelly S,Kershaw JK,Khan Z,Kioschis P,Klages S,Knights AJ,Kosiura A,Kovar-Smith C,Laird GK,Langford C,Lawlor S,Leversha M,Lewis L,Liu W,Lloyd C,Lloyd DM,Loulseged H,Loveland JE,Lovell JD,Lozado R,Lu J,Lyne R,Ma J,Maheshwari M,Matthews LH,McDowall J,McLaren S,McMurray A,Meidl P,Meitinger T,Milne S,Miner G,Mistry SL,Morgan M,Morris S,M?ller I,Mullikin JC,Nguyen N,Nordsiek G,Nyakatura G,O'Dell CN,Okwuonu G,Palmer S,Pandian R,Parker D,Parrish J,Pasternak S,Patel D,Pearce AV,Pearson DM,Pelan SE,Perez L,Porter KM,Ramsey Y,Reichwald K,Rhodes S,Ridler KA,Schlessinger D,Schueler MG,Sehra HK,Shaw-Smith C,Shen H,Sheridan EM,Shownkeen R,Skuce CD,Smith ML,Sotheran EC,Steingruber HE,Steward CA,Storey R,Swann RM,Swarbreck D,Tabor PE,Taudien S,Taylor T,Teague B,Thomas K,Thorpe A,Timms K,Tracey A,Trevanion S,Tromans AC,d'Urso M,Verduzco D,Villasana D,Waldron L,Wall M,Wang Q,Warren J,Warry GL,Wei X,West A,Whitehead SL,Whiteley MN,Wilkinson JE,Willey DL,Williams G,Williams L,Williamson A,Williamson H,Wilming L,Woodmansey RL,Wray PW,Yen J,Zhang J,Zhou J,Zoghbi H,Zorilla S,Buck D,Reinhardt R,Poustka A,Rosenthal A,Lehrach H,Meindl A,Minx PJ,Hillier LW,Willard HF,Wilson RK,Waterston RH,Rice CM,Vaudin M,Coulson A,Nelson DL,Weinstock G,Sulston JE,Durbin R,Hubbard T,Gibbs RA,Beck S,Rogers J,Bentley DR

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KLHL34 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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