ALPP cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	ALPP
Entrez Gene ID	250
Full Name	alkaline phosphatase, placental
Synonyms	ALP,PALP,PLAP,PLAP-1
General protein information	Preferred Names alkaline phosphatase, placental Names alkaline phosphatase, placental type alkaline phosphatase Regan isozyme alkaline phosphomonoesterase glycerophosphatase placental alkaline phosphatase 1
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 2 Map Location: 2q37.1
Summary	The protein encoded by this gene is an alkaline phosphatase, a metalloenzyme that catalyzes the hydrolysis of phosphoric acid monoesters. It belongs to a multigene family composed of four alkaline phosphatase isoenzymes. The enzyme functions as a homodimer and has a catalytic site containing one magnesium and two zinc ions, which are required for its enzymatic function. The protein is primarily expressed in placental and endometrial tissue; however, strong ectopic expression has been detected in ovarian adenocarcinoma, serous cystadenocarcinoma, and other ovarian cancer cells. [provided by RefSeq, Jan 2015].
Disorder MIM:	171800

mRNA and Protein(s)

mRNA	Protein	Name
NM_001632.4	NP_001623.3	alkaline phosphatase, placental type preproprotein
NM_001632.5	NP_001623.3	alkaline phosphatase, placental type preproprotein

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Alpi	NP_001074551.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP010596	XP_314561.4
Rattus norvegicus (Norway rat)	Alpi	NP_073156.3
Drosophila melanogaster (fruit fly)	Aph-4	NP_524601.2
Homo sapiens (human)	ALPP	NP_001623.3
Pan troglodytes (chimpanzee)	ALPP	XP_001146156.2

Gene Ontology
Bibliography

Related articles in PubMed

Placental biomarkers and angiogenic factors in oral fluids of patients with preeclampsia.
Chaparro A, Gaedechens D, Ram?rez V, Zu?iga E, Kusanovic JP, Inostroza C, Varas-Godoy M, Silva K, Salomon C, Rice G, Illanes SE
Prenatal diagnosis36(5)476-82(2016 May)

Metastatic Treated Malignant Germ Cell Tumors: Is SALL4 a Better Marker Than Placental Alkaline Phosphatase?
Andeen NK, Tretiakova MS
Applied immunohistochemistry & molecular morphology : AIMM24(3)210-4(2016 Mar)

Identification of a region within the placental alkaline phosphatase mRNA that mediates p180-dependent targeting to the endoplasmic reticulum.
Cui XA, Zhang Y, Hong SJ, Palazzo AF
The Journal of biological chemistry288(41)29633-41(2013 Oct)

Refined structures of placental alkaline phosphatase show a consistent pattern of interactions at the peripheral site.
Stec B, Cheltsov A, Mill?n JL
Acta crystallographica. Section F, Structural biology and crystallization communications66(Pt 8)866-70(2010 Aug)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Concentrations of PLAP were elevated in gingival crevicular fluid of patients with pre-eclampsia.
Title: Placental biomarkers and angiogenic factors in oral fluids of patients with preeclampsia.

SALL4 also outperformed PLAP on a small sample of cytology blocks. Although SALL4 is not entirely specific, it is a highly sensitive marker with strong diffuse nuclear reactivity in the majority of MGCTs in the posttreatment setting, at significantly higher levels than PLAP
Title: Metastatic Treated Malignant Germ Cell Tumors: Is SALL4 a Better Marker Than Placental Alkaline Phosphatase?

Quantum-mechanical computational methods were employed to study the catalytic mechanism of human placental AP (PLAP). An active-site model was used, constructed on the basis of the X-ray crystal structure of the enzyme.
Title: Catalytic activity of human placental alkaline phosphatase (PLAP): insights from a computational study.

term placental explants, but not their conditioned medium, can de-phosphorylate IGFBP-1 through the action of placental alkaline phosphatase
Title: Placental alkaline phosphatase de-phosphorylates insulin-like growth factor (IGF)-binding protein-1.

A candidate gene, ALPP, encoding the placental alkaline phosphatase, was identified as being potentially involved in recurrent spontaneous abortion.
Title: Polymorphisms of human placental alkaline phosphatase are associated with in vitro fertilization success and recurrent pregnancy loss.

The following ALPP gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ALPP cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu18818	NM_001632.5 Latest version!	Homo sapiens alkaline phosphatase, placental (ALPP), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$219.50-$307.30 $439.00
View Old Accession Versions >>
OHu18818	NM_001632.4	Homo sapiens alkaline phosphatase, placental (ALPP), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$265.30 $379.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

ALPP ( NM_001632.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_001623.3 Homo sapiens alkaline phosphatase, placental (ALPP), mRNA.

Price & Availability↑

CloneID	OHu18818
Clone ID Related Accession (Same CDS sequence)	NM_001632.4 , NM_001632.5
Accession Version	NM_001632.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1608bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-21
Organism	Homo sapiens(human)
Product	alkaline phosphatase, placental type preproprotein
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC094743.1, BC009647.1 and AF217992.1. This sequence is a reference standard in the RefSeqGene project. On Dec 7, 2018 this sequence version replaced NM_001632.4. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC068501.1, BC094743.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2142853, SAMEA2149398 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## CDS uses downstream in-frame AUG :: upstream AUG and CDS extension is not conserved MANE Ensembl match :: ENST00000392027.3/ ENSP00000375881.2 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGCTGGGGC CCTGCATGCT GCTGCTGCTG CTGCTGCTGG GCCTGAGGCT ACAGCTCTCC 
CTGGGCATCA TCCCAGTTGA GGAGGAGAAC CCGGACTTCT GGAACCGCGA GGCAGCCGAG 
GCCCTGGGTG CCGCCAAGAA GCTGCAGCCT GCACAGACAG CCGCCAAGAA CCTCATCATC 
TTCCTGGGCG ATGGGATGGG GGTGTCTACG GTGACAGCTG CCAGGATCCT AAAAGGGCAG 
AAGAAGGACA AACTGGGGCC TGAGATACCC CTGGCCATGG ACCGCTTCCC ATATGTGGCT 
CTGTCCAAGA CATACAATGT AGACAAACAT GTGCCAGACA GTGGAGCCAC AGCCACGGCC 
TACCTGTGCG GGGTCAAGGG CAACTTCCAG ACCATTGGCT TGAGTGCAGC CGCCCGCTTT 
AACCAGTGCA ACACGACACG CGGCAACGAG GTCATCTCCG TGATGAATCG GGCCAAGAAA 
GCAGGGAAGT CAGTGGGAGT GGTAACCACC ACACGAGTGC AGCACGCCTC GCCAGCCGGC 
ACCTACGCCC ACACGGTGAA CCGCAACTGG TACTCGGACG CCGACGTGCC TGCCTCCGCC 
CGCCAGGAGG GGTGCCAGGA CATCGCTACG CAGCTCATCT CCAACATGGA CATTGACGTG 
ATCCTAGGTG GAGGCCGAAA GTACATGTTT CGCATGGGAA CCCCAGACCC TGAGTACCCA 
GATGACTACA GCCAAGGTGG GACCAGGCTG GACGGGAAGA ATCTGGTGCA GGAATGGCTG 
GCGAAGCGCC AGGGTGCCCG GTATGTGTGG AACCGCACTG AGCTCATGCA GGCTTCCCTG 
GACCCGTCTG TGACCCATCT CATGGGTCTC TTTGAGCCTG GAGACATGAA ATACGAGATC 
CACCGAGACT CCACACTGGA CCCCTCCCTG ATGGAGATGA CAGAGGCTGC CCTGCGCCTG 
CTGAGCAGGA ACCCCCGCGG CTTCTTCCTC TTCGTGGAGG GTGGTCGCAT CGACCATGGT 
CATCATGAAA GCAGGGCTTA CCGGGCACTG ACTGAGACGA TCATGTTCGA CGACGCCATT 
GAGAGGGCGG GCCAGCTCAC CAGCGAGGAG GACACGCTGA GCCTCGTCAC TGCCGACCAC 
TCCCACGTCT TCTCCTTCGG AGGCTACCCC CTGCGAGGGA GCTCCATCTT CGGGCTGGCC 
CCTGGCAAGG CCCGGGACAG GAAGGCCTAC ACGGTCCTCC TATACGGAAA CGGTCCAGGC 
TATGTGCTCA AGGACGGCGC CCGGCCGGAT GTTACCGAGA GCGAGAGCGG GAGCCCCGAG 
TATCGGCAGC AGTCAGCAGT GCCCCTGGAC GAAGAGACCC ACGCAGGCGA GGACGTGGCG 
GTGTTCGCGC GCGGCCCGCA GGCGCACCTG GTTCACGGCG TGCAGGAGCA GACCTTCATA 
GCGCACGTCA TGGCCTTCGC CGCCTGCCTG GAGCCCTACA CCGCCTGCGA CCTGGCGCCC 
CCCGCCGGCA CCACCGACGC CGCGCACCCG GGGCGGTCCG TGGTCCCCGC GTTGCTTCCT 
CTGCTGGCCG GGACCCTGCT GCTGCTGGAG ACGGCCACTG CTCCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001623.3
CDS	53..1660
Translation	MLGPCMLLLLLLLGLRLQLSLGIIPVEEENPDFWNREAAEALGAAKKLQPAQTAAKNLIIFLGDGMGVSTVTAARILKGQKKDKLGPEIPLAMDRFPYVALSKTYNVDKHVPDSGATATAYLCGVKGNFQTIGLSAAARFNQCNTTRGNEVISVMNRAKKAGKSVGVVTTTRVQHASPAGTYAHTVNRNWYSDADVPASARQEGCQDIATQLISNMDIDVILGGGRKYMFRMGTPDPEYPDDYSQGGTRLDGKNLVQEWLAKRQGARYVWNRTELMQASLDPSVTHLMGLFEPGDMKYEIHRDSTLDPSLMEMTEAALRLLSRNPRGFFLFVEGGRIDHGHHESRAYRALTETIMFDDAIERAGQLTSEEDTLSLVTADHSHVFSFGGYPLRGSSIFGLAPGKARDRKAYTVLLYGNGPGYVLKDGARPDVTESESGSPEYRQQSAVPLDEETHAGEDVAVFARGPQAHLVHGVQEQTFIAHVMAFAACLEPYTACDLAPPAGTTDAAHPGRSVVPALLPLLAGTLLLLETATAP

Target ORF information:

RefSeq Version	NM_001632.5
Organism	Homo sapiens(human)
Definition	Homo sapiens alkaline phosphatase, placental (ALPP), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001632.5

ORF Insert Sequence:

ATGCTGGGGC CCTGCATGCT GCTGCTGCTG CTGCTGCTGG GCCTGAGGCT ACAGCTCTCC 
CTGGGCATCA TCCCAGTTGA GGAGGAGAAC CCGGACTTCT GGAACCGCGA GGCAGCCGAG 
GCCCTGGGTG CCGCCAAGAA GCTGCAGCCT GCACAGACAG CCGCCAAGAA CCTCATCATC 
TTCCTGGGCG ATGGGATGGG GGTGTCTACG GTGACAGCTG CCAGGATCCT AAAAGGGCAG 
AAGAAGGACA AACTGGGGCC TGAGATACCC CTGGCCATGG ACCGCTTCCC ATATGTGGCT 
CTGTCCAAGA CATACAATGT AGACAAACAT GTGCCAGACA GTGGAGCCAC AGCCACGGCC 
TACCTGTGCG GGGTCAAGGG CAACTTCCAG ACCATTGGCT TGAGTGCAGC CGCCCGCTTT 
AACCAGTGCA ACACGACACG CGGCAACGAG GTCATCTCCG TGATGAATCG GGCCAAGAAA 
GCAGGGAAGT CAGTGGGAGT GGTAACCACC ACACGAGTGC AGCACGCCTC GCCAGCCGGC 
ACCTACGCCC ACACGGTGAA CCGCAACTGG TACTCGGACG CCGACGTGCC TGCCTCCGCC 
CGCCAGGAGG GGTGCCAGGA CATCGCTACG CAGCTCATCT CCAACATGGA CATTGACGTG 
ATCCTAGGTG GAGGCCGAAA GTACATGTTT CGCATGGGAA CCCCAGACCC TGAGTACCCA 
GATGACTACA GCCAAGGTGG GACCAGGCTG GACGGGAAGA ATCTGGTGCA GGAATGGCTG 
GCGAAGCGCC AGGGTGCCCG GTATGTGTGG AACCGCACTG AGCTCATGCA GGCTTCCCTG 
GACCCGTCTG TGACCCATCT CATGGGTCTC TTTGAGCCTG GAGACATGAA ATACGAGATC 
CACCGAGACT CCACACTGGA CCCCTCCCTG ATGGAGATGA CAGAGGCTGC CCTGCGCCTG 
CTGAGCAGGA ACCCCCGCGG CTTCTTCCTC TTCGTGGAGG GTGGTCGCAT CGACCATGGT 
CATCATGAAA GCAGGGCTTA CCGGGCACTG ACTGAGACGA TCATGTTCGA CGACGCCATT 
GAGAGGGCGG GCCAGCTCAC CAGCGAGGAG GACACGCTGA GCCTCGTCAC TGCCGACCAC 
TCCCACGTCT TCTCCTTCGG AGGCTACCCC CTGCGAGGGA GCTCCATCTT CGGGCTGGCC 
CCTGGCAAGG CCCGGGACAG GAAGGCCTAC ACGGTCCTCC TATACGGAAA CGGTCCAGGC 
TATGTGCTCA AGGACGGCGC CCGGCCGGAT GTTACCGAGA GCGAGAGCGG GAGCCCCGAG 
TATCGGCAGC AGTCAGCAGT GCCCCTGGAC GAAGAGACCC ACGCAGGCGA GGACGTGGCG 
GTGTTCGCGC GCGGCCCGCA GGCGCACCTG GTTCACGGCG TGCAGGAGCA GACCTTCATA 
GCGCACGTCA TGGCCTTCGC CGCCTGCCTG GAGCCCTACA CCGCCTGCGA CCTGGCGCCC 
CCCGCCGGCA CCACCGACGC CGCGCACCCG GGGCGGTCCG TGGTCCCCGC GTTGCTTCCT 
CTGCTGGCCG GGACCCTGCT GCTGCTGGAG ACGGCCACTG CTCCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ALPP ( NM_001632.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_001623.3 Homo sapiens alkaline phosphatase, placental (ALPP), mRNA.

Price & Availability↑

CloneID	OHu18818
Clone ID Related Accession (Same CDS sequence)	NM_001632.4 , NM_001632.5
Accession Version	NM_001632.4	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1608bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-09-09
Organism	Homo sapiens(human)
Product	alkaline phosphatase, placental type preproprotein
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK312931.1, DA851165.1, BC094743.1, BC009647.1 and AF217992.1. This sequence is a reference standard in the RefSeqGene project. On Jan 7, 2015 this sequence version replaced NM_001632.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK312931.1, BC094743.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2142853, SAMEA2149398 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## CDS uses downstream in-frame AUG :: upstream AUG and CDS extension is not conserved ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGCTGGGGC CCTGCATGCT GCTGCTGCTG CTGCTGCTGG GCCTGAGGCT ACAGCTCTCC 
CTGGGCATCA TCCCAGTTGA GGAGGAGAAC CCGGACTTCT GGAACCGCGA GGCAGCCGAG 
GCCCTGGGTG CCGCCAAGAA GCTGCAGCCT GCACAGACAG CCGCCAAGAA CCTCATCATC 
TTCCTGGGCG ATGGGATGGG GGTGTCTACG GTGACAGCTG CCAGGATCCT AAAAGGGCAG 
AAGAAGGACA AACTGGGGCC TGAGATACCC CTGGCCATGG ACCGCTTCCC ATATGTGGCT 
CTGTCCAAGA CATACAATGT AGACAAACAT GTGCCAGACA GTGGAGCCAC AGCCACGGCC 
TACCTGTGCG GGGTCAAGGG CAACTTCCAG ACCATTGGCT TGAGTGCAGC CGCCCGCTTT 
AACCAGTGCA ACACGACACG CGGCAACGAG GTCATCTCCG TGATGAATCG GGCCAAGAAA 
GCAGGGAAGT CAGTGGGAGT GGTAACCACC ACACGAGTGC AGCACGCCTC GCCAGCCGGC 
ACCTACGCCC ACACGGTGAA CCGCAACTGG TACTCGGACG CCGACGTGCC TGCCTCCGCC 
CGCCAGGAGG GGTGCCAGGA CATCGCTACG CAGCTCATCT CCAACATGGA CATTGACGTG 
ATCCTAGGTG GAGGCCGAAA GTACATGTTT CGCATGGGAA CCCCAGACCC TGAGTACCCA 
GATGACTACA GCCAAGGTGG GACCAGGCTG GACGGGAAGA ATCTGGTGCA GGAATGGCTG 
GCGAAGCGCC AGGGTGCCCG GTATGTGTGG AACCGCACTG AGCTCATGCA GGCTTCCCTG 
GACCCGTCTG TGACCCATCT CATGGGTCTC TTTGAGCCTG GAGACATGAA ATACGAGATC 
CACCGAGACT CCACACTGGA CCCCTCCCTG ATGGAGATGA CAGAGGCTGC CCTGCGCCTG 
CTGAGCAGGA ACCCCCGCGG CTTCTTCCTC TTCGTGGAGG GTGGTCGCAT CGACCATGGT 
CATCATGAAA GCAGGGCTTA CCGGGCACTG ACTGAGACGA TCATGTTCGA CGACGCCATT 
GAGAGGGCGG GCCAGCTCAC CAGCGAGGAG GACACGCTGA GCCTCGTCAC TGCCGACCAC 
TCCCACGTCT TCTCCTTCGG AGGCTACCCC CTGCGAGGGA GCTCCATCTT CGGGCTGGCC 
CCTGGCAAGG CCCGGGACAG GAAGGCCTAC ACGGTCCTCC TATACGGAAA CGGTCCAGGC 
TATGTGCTCA AGGACGGCGC CCGGCCGGAT GTTACCGAGA GCGAGAGCGG GAGCCCCGAG 
TATCGGCAGC AGTCAGCAGT GCCCCTGGAC GAAGAGACCC ACGCAGGCGA GGACGTGGCG 
GTGTTCGCGC GCGGCCCGCA GGCGCACCTG GTTCACGGCG TGCAGGAGCA GACCTTCATA 
GCGCACGTCA TGGCCTTCGC CGCCTGCCTG GAGCCCTACA CCGCCTGCGA CCTGGCGCCC 
CCCGCCGGCA CCACCGACGC CGCGCACCCG GGGCGGTCCG TGGTCCCCGC GTTGCTTCCT 
CTGCTGGCCG GGACCCTGCT GCTGCTGGAG ACGGCCACTG CTCCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001623.3
CDS	270..1877
Translation	MLGPCMLLLLLLLGLRLQLSLGIIPVEEENPDFWNREAAEALGAAKKLQPAQTAAKNLIIFLGDGMGVSTVTAARILKGQKKDKLGPEIPLAMDRFPYVALSKTYNVDKHVPDSGATATAYLCGVKGNFQTIGLSAAARFNQCNTTRGNEVISVMNRAKKAGKSVGVVTTTRVQHASPAGTYAHTVNRNWYSDADVPASARQEGCQDIATQLISNMDIDVILGGGRKYMFRMGTPDPEYPDDYSQGGTRLDGKNLVQEWLAKRQGARYVWNRTELMQASLDPSVTHLMGLFEPGDMKYEIHRDSTLDPSLMEMTEAALRLLSRNPRGFFLFVEGGRIDHGHHESRAYRALTETIMFDDAIERAGQLTSEEDTLSLVTADHSHVFSFGGYPLRGSSIFGLAPGKARDRKAYTVLLYGNGPGYVLKDGARPDVTESESGSPEYRQQSAVPLDEETHAGEDVAVFARGPQAHLVHGVQEQTFIAHVMAFAACLEPYTACDLAPPAGTTDAAHPGRSVVPALLPLLAGTLLLLETATAP

Target ORF information:

RefSeq Version	NM_001632.4
Organism	Homo sapiens(human)
Definition	Homo sapiens alkaline phosphatase, placental (ALPP), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001632.4

ORF Insert Sequence:

ATGCTGGGGC CCTGCATGCT GCTGCTGCTG CTGCTGCTGG GCCTGAGGCT ACAGCTCTCC 
CTGGGCATCA TCCCAGTTGA GGAGGAGAAC CCGGACTTCT GGAACCGCGA GGCAGCCGAG 
GCCCTGGGTG CCGCCAAGAA GCTGCAGCCT GCACAGACAG CCGCCAAGAA CCTCATCATC 
TTCCTGGGCG ATGGGATGGG GGTGTCTACG GTGACAGCTG CCAGGATCCT AAAAGGGCAG 
AAGAAGGACA AACTGGGGCC TGAGATACCC CTGGCCATGG ACCGCTTCCC ATATGTGGCT 
CTGTCCAAGA CATACAATGT AGACAAACAT GTGCCAGACA GTGGAGCCAC AGCCACGGCC 
TACCTGTGCG GGGTCAAGGG CAACTTCCAG ACCATTGGCT TGAGTGCAGC CGCCCGCTTT 
AACCAGTGCA ACACGACACG CGGCAACGAG GTCATCTCCG TGATGAATCG GGCCAAGAAA 
GCAGGGAAGT CAGTGGGAGT GGTAACCACC ACACGAGTGC AGCACGCCTC GCCAGCCGGC 
ACCTACGCCC ACACGGTGAA CCGCAACTGG TACTCGGACG CCGACGTGCC TGCCTCCGCC 
CGCCAGGAGG GGTGCCAGGA CATCGCTACG CAGCTCATCT CCAACATGGA CATTGACGTG 
ATCCTAGGTG GAGGCCGAAA GTACATGTTT CGCATGGGAA CCCCAGACCC TGAGTACCCA 
GATGACTACA GCCAAGGTGG GACCAGGCTG GACGGGAAGA ATCTGGTGCA GGAATGGCTG 
GCGAAGCGCC AGGGTGCCCG GTATGTGTGG AACCGCACTG AGCTCATGCA GGCTTCCCTG 
GACCCGTCTG TGACCCATCT CATGGGTCTC TTTGAGCCTG GAGACATGAA ATACGAGATC 
CACCGAGACT CCACACTGGA CCCCTCCCTG ATGGAGATGA CAGAGGCTGC CCTGCGCCTG 
CTGAGCAGGA ACCCCCGCGG CTTCTTCCTC TTCGTGGAGG GTGGTCGCAT CGACCATGGT 
CATCATGAAA GCAGGGCTTA CCGGGCACTG ACTGAGACGA TCATGTTCGA CGACGCCATT 
GAGAGGGCGG GCCAGCTCAC CAGCGAGGAG GACACGCTGA GCCTCGTCAC TGCCGACCAC 
TCCCACGTCT TCTCCTTCGG AGGCTACCCC CTGCGAGGGA GCTCCATCTT CGGGCTGGCC 
CCTGGCAAGG CCCGGGACAG GAAGGCCTAC ACGGTCCTCC TATACGGAAA CGGTCCAGGC 
TATGTGCTCA AGGACGGCGC CCGGCCGGAT GTTACCGAGA GCGAGAGCGG GAGCCCCGAG 
TATCGGCAGC AGTCAGCAGT GCCCCTGGAC GAAGAGACCC ACGCAGGCGA GGACGTGGCG 
GTGTTCGCGC GCGGCCCGCA GGCGCACCTG GTTCACGGCG TGCAGGAGCA GACCTTCATA 
GCGCACGTCA TGGCCTTCGC CGCCTGCCTG GAGCCCTACA CCGCCTGCGA CCTGGCGCCC 
CCCGCCGGCA CCACCGACGC CGCGCACCCG GGGCGGTCCG TGGTCCCCGC GTTGCTTCCT 
CTGCTGGCCG GGACCCTGCT GCTGCTGGAG ACGGCCACTG CTCCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Placental biomarkers and angiogenic factors in oral fluids of patients with preeclampsia.
Prenatal diagnosis36(5)476-82(2016 May)
Chaparro A,Gaedechens D,Ram?rez V,Zu?iga E,Kusanovic JP,Inostroza C,Varas-Godoy M,Silva K,Salomon C,Rice G,Illanes SE

Metastatic Treated Malignant Germ Cell Tumors: Is SALL4 a Better Marker Than Placental Alkaline Phosphatase?
Applied immunohistochemistry & molecular morphology : AIMM24(3)210-4(2016 Mar)
Andeen NK,Tretiakova MS

Identification of a region within the placental alkaline phosphatase mRNA that mediates p180-dependent targeting to the endoplasmic reticulum.
The Journal of biological chemistry288(41)29633-41(2013 Oct)
Cui XA,Zhang Y,Hong SJ,Palazzo AF

Refined structures of placental alkaline phosphatase show a consistent pattern of interactions at the peripheral site.
Acta crystallographica. Section F, Structural biology and crystallization communications66(Pt 8)866-70(2010 Aug)
Stec B,Cheltsov A,Mill?n JL