| Gene Symbol | IQSEC2 |
| Entrez Gene ID | 23096 |
| Full Name | IQ motif and Sec7 domain 2 |
| Synonyms | BRAG1,MRX1,MRX18,MRX78 |
| General protein information |
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| Gene Type | protein-coding |
| Organism | Homo sapiens(human) |
| Genome | |
| Summary | This gene encodes a guanine nucleotide exchange factor for the ARF family of small GTP-binding proteins. The encoded protein is a component of the postsynaptic density at excitatory synapses, and may play a critical role in cytoskeletal and synaptic organization through the activation of selected ARF substrates including ARF1 and ARF6. Mutations in this gene have been implicated in nonsyndromic X-linked cognitive disability. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2011]. |
| Disorder MIM: | |
| Disorder Html: | Mental retardation, X-linked 1/78, 309530 (3) |







































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