CLECL1 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	CLECL1
Entrez Gene ID	160365
Full Name	C-type lectin like 1
Synonyms	DCAL-1,DCAL1
General protein information	Preferred Names C-type lectin like 1 Names C-type lectin-like domain family 1 DC-associated lectin-1 dendritic cell-associated lectin 1 type II transmembrane protein DCAL1
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 12 Map Location: 12p13.31
Summary	This gene encodes a type II transmembrane, C-type lectin-like protein that is highly expressed on dendritic and B cells. This protein may act as a T-cell costimulatory molecule that enhances interleukin-4 production, and maybe involved in the regulation of the immune response. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011].
Disorder MIM:	607467

mRNA and Protein(s)

mRNA	Protein	Name
XM_011520574.2	XP_011518876.1	C-type lectin-like domain family 1 isoform X1
NM_172004.3	NP_742001.1	C-type lectin-like domain family 1 isoform 1
NM_001253750.1	NP_001240679.1	C-type lectin-like domain family 1 isoform 3
NM_001267701.1	NP_001254630.1	C-type lectin-like domain family 1 isoform 4
XM_017018885.1	XP_016874374.1	C-type lectin-like domain family 1 isoform X2

Pathways from BioSystems

Homologies

Homo sapiens (human)	CLECL1	NP_001240679.1
Pan troglodytes (chimpanzee)	CLECL1	XP_001136753.3

Gene Ontology
Bibliography

Related articles in PubMed

New genetic associations detected in a host response study to hepatitis B vaccine.
Davila S, Froeling FE, Tan A, Bonnard C, Boland GJ, Snippe H, Hibberd ML, Seielstad M
Genes and immunity11(3)232-8(2010 Apr)

Targeting C-type lectin-like molecule-1 for antibody-mediated immunotherapy in acute myeloid leukemia.
Zhao X, Singh S, Pardoux C, Zhao J, Hsi ED, Abo A, Korver W
Haematologica95(1)71-8(2010 Jan)

Ligation of dendritic cell-associated lectin-1 induces partial maturation of human monocyte derived dendritic cells.
Ryan EJ, Magaletti D, Draves KE, Clark EA
Human immunology70(1)1-5(2009 Jan)

Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls.

Nature447(7145)661-78(2007 Jun)

Dendritic cell-associated lectin-1: a novel dendritic cell-associated, C-type lectin-like molecule enhances T cell secretion of IL-4.
Ryan EJ, Marshall AJ, Magaletti D, Floyd H, Draves KE, Olson NE, Clark EA
Journal of immunology (Baltimore, Md. : 1950)169(10)5638-48(2002 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Observational study of gene-disease association. (HuGE Navigator)
Title: New genetic associations detected in a host response study to hepatitis B vaccine.

C-type lectin-like molecule-1 is expressed in 86.5% of cases of acute myeloid leukemia, in 54.5% of acute myeloid leukemia CD34positiveCD38negative stem cells, but not in acute lymphoblastic leukemia blast cells.
Title: Targeting C-type lectin-like molecule-1 for antibody-mediated immunotherapy in acute myeloid leukemia.

incubation of immature DCs (iDCs) with an anti-DCAL-1 monoclonal antibody (mAb) induced downstream signaling, including phosphorylation of c-Jun N-terminal kinase (JNK) and p44/42 MAP kinase.
Title: Ligation of dendritic cell-associated lectin-1 induces partial maturation of human monocyte derived dendritic cells.

DCAL-1, highly expressed on dendritic cells and B lymphocytes, acts as a T cell costimulatory molecule which skews CD4+ T cells toward a Th2 response by enhancing their secretion of IL-4.
Title: Dendritic cell-associated lectin-1: a novel dendritic cell-associated, C-type lectin-like molecule enhances T cell secretion of IL-4.

The following CLECL1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CLECL1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu27138	NM_172004.3 Latest version!	Homo sapiens C-type lectin like 1 (CLECL1), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu27196	NM_001253750.1 Latest version!	Homo sapiens C-type lectin like 1 (CLECL1), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
OHu27456	NM_001267701.1 Latest version!	Homo sapiens C-type lectin like 1 (CLECL1), transcript variant 4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
OHu27196	XM_011520574.2 Latest version!	Homo sapiens C-type lectin like 1 (CLECL1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
OHu83556	XM_017018885.1 Latest version!	Homo sapiens C-type lectin like 1 (CLECL1), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
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2-4 Clone	40% OFF
5 or more Clone	50% OFF
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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

CLECL1 ( NM_172004.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_742001.1 Homo sapiens C-type lectin like 1 (CLECL1), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu27138
Clone ID Related Accession (Same CDS sequence)	NM_172004.3
Accession Version	NM_172004.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 504bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-23
Organism	Homo sapiens(human)
Product	C-type lectin-like domain family 1 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC093859.1 and BX103210.1. On or before Jun 12, 2012 this sequence version replaced NM_001253748.1, NM_172004.2. Transcript Variant: This variant (1) represents the predominant transcript, and encodes isoform 1. ##Evidence-Data-START## Transcript exon combination :: BC093857.1, SRR1163658.435833.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2155751 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on expression ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGTTAGTA ATTTCTTCCA TGTCATACAA GTATTCGAGA AATCTGCTAC CTTGATTAGT 
AAGACTGAAC ACATTGGTTT TGTCATTTAT TCATGGAGGA AGTCCACCAC CCACTTGGGG 
AGCAGAAGGA AATTTGCCAT CTCAATTTAC TTATCAGAAG TTTCTTTGCA GAAATATGAT 
TGTCCCTTCA GTGGGACATC ATTTGTGGTC TTCTCTCTCT TTTTGATCTG TGCAATGGCT 
GGAGATGTAG TCTACGCTGA CATCAAAACT GTTCGGACTT CCCCGTTAGA ACTCGCGTTT 
CCACTTCAGA GATCTGTTTC TTTCAACTTT TCTACTGTCC ATAAATCATG TCCTGCCAAA 
GACTGGAAGG TGCATAAGGG AAAATGTTAC TGGATTGCTG AAACTAAGAA ATCTTGGAAC 
AAAAGTCAAA ATGACTGTGC CATAAACAAT TCATATCTCA TGGTGATTCA AGACATTACT 
GCTATGGTGA GATTTAACAT TTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_742001.1
CDS	36..539
Translation	MVSNFFHVIQVFEKSATLISKTEHIGFVIYSWRKSTTHLGSRRKFAISIYLSEVSLQKYDCPFSGTSFVVFSLFLICAMAGDVVYADIKTVRTSPLELAFPLQRSVSFNFSTVHKSCPAKDWKVHKGKCYWIAETKKSWNKSQNDCAINNSYLMVIQDITAMVRFNI

Target ORF information:

RefSeq Version	NM_172004.3
Organism	Homo sapiens(human)
Definition	Homo sapiens C-type lectin like 1 (CLECL1), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_172004.3

ORF Insert Sequence:

ATGGTTAGTA ATTTCTTCCA TGTCATACAA GTATTCGAGA AATCTGCTAC CTTGATTAGT 
AAGACTGAAC ACATTGGTTT TGTCATTTAT TCATGGAGGA AGTCCACCAC CCACTTGGGG 
AGCAGAAGGA AATTTGCCAT CTCAATTTAC TTATCAGAAG TTTCTTTGCA GAAATATGAT 
TGTCCCTTCA GTGGGACATC ATTTGTGGTC TTCTCTCTCT TTTTGATCTG TGCAATGGCT 
GGAGATGTAG TCTACGCTGA CATCAAAACT GTTCGGACTT CCCCGTTAGA ACTCGCGTTT 
CCACTTCAGA GATCTGTTTC TTTCAACTTT TCTACTGTCC ATAAATCATG TCCTGCCAAA 
GACTGGAAGG TGCATAAGGG AAAATGTTAC TGGATTGCTG AAACTAAGAA ATCTTGGAAC 
AAAAGTCAAA ATGACTGTGC CATAAACAAT TCATATCTCA TGGTGATTCA AGACATTACT 
GCTATGGTGA GATTTAACAT TTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CLECL1 ( NM_001253750.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001240679.1 Homo sapiens C-type lectin like 1 (CLECL1), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu27196
Clone ID Related Accession (Same CDS sequence)	XM_011520574.2 , NM_001253750.1
Accession Version	NM_001253750.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 576bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-22
Organism	Homo sapiens(human)
Product	C-type lectin-like domain family 1 isoform 3
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC093859.1 and BC042176.1. Transcript Variant: This variant (3) contains two additional exons at the 3' end resulting in a novel 3' coding region and 3' UTR compared to variant 1. It encodes isoform 3 which is longer and has a distinct C-terminus, compared to isoform 1. ##Evidence-Data-START## RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA2146236 [ECO:0000350] ##Evidence-Data-END##

ATGGTTAGTA ATTTCTTCCA TGTCATACAA GTATTCGAGA AATCTGCTAC CTTGATTAGT 
AAGACTGAAC ACATTGGTTT TGTCATTTAT TCATGGAGGA AGTCCACCAC CCACTTGGGG 
AGCAGAAGGA AATTTGCCAT CTCAATTTAC TTATCAGAAG TTTCTTTGCA GAAATATGAT 
TGTCCCTTCA GTGGGACATC ATTTGTGGTC TTCTCTCTCT TTTTGATCTG TGCAATGGCT 
GGAGATGTAG TCTACGCTGA CATCAAAACT GTTCGGACTT CCCCGTTAGA ACTCGCGTTT 
CCACTTCAGA GATCTGTTTC TTTCAACTTT TCTACTGTCC ATAAATCATG TCCTGCCAAA 
GACTGGAAGG TGCATAAGGG AAAATGTTAC TGGATTGCTG AAACTAAGAA ATCTTGGAAC 
AAAAGTCAAA ATGACTGTGC CATAAACAAT TCATATCTCA TGGTGATTCA AGACATTACT 
GCTATGCTGA TCACCTTTTT GCTGTACCTT CAAATGGCAT TTCTTCAATG TGTGTACATC 
TCTGATGTCT CTGTGTATCC AAATTTCTTC TTGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001240679.1
CDS	36..611
Translation	MVSNFFHVIQVFEKSATLISKTEHIGFVIYSWRKSTTHLGSRRKFAISIYLSEVSLQKYDCPFSGTSFVVFSLFLICAMAGDVVYADIKTVRTSPLELAFPLQRSVSFNFSTVHKSCPAKDWKVHKGKCYWIAETKKSWNKSQNDCAINNSYLMVIQDITAMLITFLLYLQMAFLQCVYISDVSVYPNFFL

Target ORF information:

RefSeq Version	NM_001253750.1
Organism	Homo sapiens(human)
Definition	Homo sapiens C-type lectin like 1 (CLECL1), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001253750.1

ORF Insert Sequence:

ATGGTTAGTA ATTTCTTCCA TGTCATACAA GTATTCGAGA AATCTGCTAC CTTGATTAGT 
AAGACTGAAC ACATTGGTTT TGTCATTTAT TCATGGAGGA AGTCCACCAC CCACTTGGGG 
AGCAGAAGGA AATTTGCCAT CTCAATTTAC TTATCAGAAG TTTCTTTGCA GAAATATGAT 
TGTCCCTTCA GTGGGACATC ATTTGTGGTC TTCTCTCTCT TTTTGATCTG TGCAATGGCT 
GGAGATGTAG TCTACGCTGA CATCAAAACT GTTCGGACTT CCCCGTTAGA ACTCGCGTTT 
CCACTTCAGA GATCTGTTTC TTTCAACTTT TCTACTGTCC ATAAATCATG TCCTGCCAAA 
GACTGGAAGG TGCATAAGGG AAAATGTTAC TGGATTGCTG AAACTAAGAA ATCTTGGAAC 
AAAAGTCAAA ATGACTGTGC CATAAACAAT TCATATCTCA TGGTGATTCA AGACATTACT 
GCTATGCTGA TCACCTTTTT GCTGTACCTT CAAATGGCAT TTCTTCAATG TGTGTACATC 
TCTGATGTCT CTGTGTATCC AAATTTCTTC TTGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CLECL1 ( NM_001267701.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001254630.1 Homo sapiens C-type lectin like 1 (CLECL1), transcript variant 4, mRNA.

Price & Availability↑

CloneID	OHu27456
Clone ID Related Accession (Same CDS sequence)	NM_001267701.1
Accession Version	NM_001267701.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 504bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-23
Organism	Homo sapiens(human)
Product	C-type lectin-like domain family 1 isoform 4
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC093859.1, DA619574.1 and BC042176.1. Transcript Variant: This variant (4) contains an additional exon at the 3' end resulting in a novel 3' coding region and 3' UTR compared to variant 1. It encodes isoform 4 which is the same length and has a distinct C-terminus, compared to isoform 1. ##Evidence-Data-START## Transcript exon combination :: SRR1163658.559816.1, SRR1163657.441837.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2155751 [ECO:0000348] ##Evidence-Data-END##

ATGGTTAGTA ATTTCTTCCA TGTCATACAA GTATTCGAGA AATCTGCTAC CTTGATTAGT 
AAGACTGAAC ACATTGGTTT TGTCATTTAT TCATGGAGGA AGTCCACCAC CCACTTGGGG 
AGCAGAAGGA AATTTGCCAT CTCAATTTAC TTATCAGAAG TTTCTTTGCA GAAATATGAT 
TGTCCCTTCA GTGGGACATC ATTTGTGGTC TTCTCTCTCT TTTTGATCTG TGCAATGGCT 
GGAGATGTAG TCTACGCTGA CATCAAAACT GTTCGGACTT CCCCGTTAGA ACTCGCGTTT 
CCACTTCAGA GATCTGTTTC TTTCAACTTT TCTACTGTCC ATAAATCATG TCCTGCCAAA 
GACTGGAAGG TGCATAAGGG AAAATGTTAC TGGATTGCTG AAACTAAGAA ATCTTGGAAC 
AAAAGTCAAA ATGACTGTGC CATAAACAAT TCATATCTCA TGGTGATTCA AGACATTACT 
GCTATGAAAT CCAATCTTTT TTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001254630.1
CDS	36..539
Translation	MVSNFFHVIQVFEKSATLISKTEHIGFVIYSWRKSTTHLGSRRKFAISIYLSEVSLQKYDCPFSGTSFVVFSLFLICAMAGDVVYADIKTVRTSPLELAFPLQRSVSFNFSTVHKSCPAKDWKVHKGKCYWIAETKKSWNKSQNDCAINNSYLMVIQDITAMKSNLF

Target ORF information:

RefSeq Version	NM_001267701.1
Organism	Homo sapiens(human)
Definition	Homo sapiens C-type lectin like 1 (CLECL1), transcript variant 4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001267701.1

ORF Insert Sequence:

ATGGTTAGTA ATTTCTTCCA TGTCATACAA GTATTCGAGA AATCTGCTAC CTTGATTAGT 
AAGACTGAAC ACATTGGTTT TGTCATTTAT TCATGGAGGA AGTCCACCAC CCACTTGGGG 
AGCAGAAGGA AATTTGCCAT CTCAATTTAC TTATCAGAAG TTTCTTTGCA GAAATATGAT 
TGTCCCTTCA GTGGGACATC ATTTGTGGTC TTCTCTCTCT TTTTGATCTG TGCAATGGCT 
GGAGATGTAG TCTACGCTGA CATCAAAACT GTTCGGACTT CCCCGTTAGA ACTCGCGTTT 
CCACTTCAGA GATCTGTTTC TTTCAACTTT TCTACTGTCC ATAAATCATG TCCTGCCAAA 
GACTGGAAGG TGCATAAGGG AAAATGTTAC TGGATTGCTG AAACTAAGAA ATCTTGGAAC 
AAAAGTCAAA ATGACTGTGC CATAAACAAT TCATATCTCA TGGTGATTCA AGACATTACT 
GCTATGAAAT CCAATCTTTT TTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CLECL1 ( XM_011520574.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011518876.1 Homo sapiens C-type lectin like 1 (CLECL1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu27196
Clone ID Related Accession (Same CDS sequence)	XM_011520574.2 , NM_001253750.1
Accession Version	XM_011520574.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 576bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	C-type lectin-like domain family 1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000012.12) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011520574.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGTTAGTA ATTTCTTCCA TGTCATACAA GTATTCGAGA AATCTGCTAC CTTGATTAGT 
AAGACTGAAC ACATTGGTTT TGTCATTTAT TCATGGAGGA AGTCCACCAC CCACTTGGGG 
AGCAGAAGGA AATTTGCCAT CTCAATTTAC TTATCAGAAG TTTCTTTGCA GAAATATGAT 
TGTCCCTTCA GTGGGACATC ATTTGTGGTC TTCTCTCTCT TTTTGATCTG TGCAATGGCT 
GGAGATGTAG TCTACGCTGA CATCAAAACT GTTCGGACTT CCCCGTTAGA ACTCGCGTTT 
CCACTTCAGA GATCTGTTTC TTTCAACTTT TCTACTGTCC ATAAATCATG TCCTGCCAAA 
GACTGGAAGG TGCATAAGGG AAAATGTTAC TGGATTGCTG AAACTAAGAA ATCTTGGAAC 
AAAAGTCAAA ATGACTGTGC CATAAACAAT TCATATCTCA TGGTGATTCA AGACATTACT 
GCTATGCTGA TCACCTTTTT GCTGTACCTT CAAATGGCAT TTCTTCAATG TGTGTACATC 
TCTGATGTCT CTGTGTATCC AAATTTCTTC TTGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011518876.1
CDS	79..654
Translation	MVSNFFHVIQVFEKSATLISKTEHIGFVIYSWRKSTTHLGSRRKFAISIYLSEVSLQKYDCPFSGTSFVVFSLFLICAMAGDVVYADIKTVRTSPLELAFPLQRSVSFNFSTVHKSCPAKDWKVHKGKCYWIAETKKSWNKSQNDCAINNSYLMVIQDITAMLITFLLYLQMAFLQCVYISDVSVYPNFFL

Target ORF information:

RefSeq Version	XM_011520574.2
Organism	Homo sapiens(human)
Definition	Homo sapiens C-type lectin like 1 (CLECL1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011520574.2

ORF Insert Sequence:

ATGGTTAGTA ATTTCTTCCA TGTCATACAA GTATTCGAGA AATCTGCTAC CTTGATTAGT 
AAGACTGAAC ACATTGGTTT TGTCATTTAT TCATGGAGGA AGTCCACCAC CCACTTGGGG 
AGCAGAAGGA AATTTGCCAT CTCAATTTAC TTATCAGAAG TTTCTTTGCA GAAATATGAT 
TGTCCCTTCA GTGGGACATC ATTTGTGGTC TTCTCTCTCT TTTTGATCTG TGCAATGGCT 
GGAGATGTAG TCTACGCTGA CATCAAAACT GTTCGGACTT CCCCGTTAGA ACTCGCGTTT 
CCACTTCAGA GATCTGTTTC TTTCAACTTT TCTACTGTCC ATAAATCATG TCCTGCCAAA 
GACTGGAAGG TGCATAAGGG AAAATGTTAC TGGATTGCTG AAACTAAGAA ATCTTGGAAC 
AAAAGTCAAA ATGACTGTGC CATAAACAAT TCATATCTCA TGGTGATTCA AGACATTACT 
GCTATGCTGA TCACCTTTTT GCTGTACCTT CAAATGGCAT TTCTTCAATG TGTGTACATC 
TCTGATGTCT CTGTGTATCC AAATTTCTTC TTGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CLECL1 ( XM_017018885.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016874374.1 Homo sapiens C-type lectin like 1 (CLECL1), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu83556
Clone ID Related Accession (Same CDS sequence)	XM_017018885.1
Accession Version	XM_017018885.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 408bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	C-type lectin-like domain family 1 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000012.12) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAAATATG ATTGTCCCTT CAGTGGGACA TCATTTGTGG TCTTCTCTCT CTTTTTGATC 
TGTGCAATGG CTGGAGATGT AGTCTACGCT GACATCAAAA CTGTTCGGAC TTCCCCGTTA 
GAACTCGCGT TTCCACTTCA GAGATCTGTT TCTTTCAACT TTTCTACTGT CCATAAATCA 
TGTCCTGCCA AAGACTGGAA GGTGCATAAG GGAAAATGTT ACTGGATTGC TGAAACTAAG 
AAATCTTGGA ACAAAAGTCA AAATGACTGT GCCATAAACA ATTCATATCT CATGGTGATT 
CAAGACATTA CTGCTATGCT GATCACCTTT TTGCTGTACC TTCAAATGGC ATTTCTTCAA 
TGTGTGTACA TCTCTGATGT CTCTGTGTAT CCAAATTTCT TCTTGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016874374.1
CDS	84..491
Translation	MKYDCPFSGTSFVVFSLFLICAMAGDVVYADIKTVRTSPLELAFPLQRSVSFNFSTVHKSCPAKDWKVHKGKCYWIAETKKSWNKSQNDCAINNSYLMVIQDITAMLITFLLYLQMAFLQCVYISDVSVYPNFFL

Target ORF information:

RefSeq Version	XM_017018885.1
Organism	Homo sapiens(human)
Definition	Homo sapiens C-type lectin like 1 (CLECL1), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017018885.1

ORF Insert Sequence:

ATGAAATATG ATTGTCCCTT CAGTGGGACA TCATTTGTGG TCTTCTCTCT CTTTTTGATC 
TGTGCAATGG CTGGAGATGT AGTCTACGCT GACATCAAAA CTGTTCGGAC TTCCCCGTTA 
GAACTCGCGT TTCCACTTCA GAGATCTGTT TCTTTCAACT TTTCTACTGT CCATAAATCA 
TGTCCTGCCA AAGACTGGAA GGTGCATAAG GGAAAATGTT ACTGGATTGC TGAAACTAAG 
AAATCTTGGA ACAAAAGTCA AAATGACTGT GCCATAAACA ATTCATATCT CATGGTGATT 
CAAGACATTA CTGCTATGCT GATCACCTTT TTGCTGTACC TTCAAATGGC ATTTCTTCAA 
TGTGTGTACA TCTCTGATGT CTCTGTGTAT CCAAATTTCT TCTTGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

New genetic associations detected in a host response study to hepatitis B vaccine.
Genes and immunity11(3)232-8(2010 Apr)
Davila S,Froeling FE,Tan A,Bonnard C,Boland GJ,Snippe H,Hibberd ML,Seielstad M

Targeting C-type lectin-like molecule-1 for antibody-mediated immunotherapy in acute myeloid leukemia.
Haematologica95(1)71-8(2010 Jan)
Zhao X,Singh S,Pardoux C,Zhao J,Hsi ED,Abo A,Korver W

Ligation of dendritic cell-associated lectin-1 induces partial maturation of human monocyte derived dendritic cells.
Human immunology70(1)1-5(2009 Jan)
Ryan EJ,Magaletti D,Draves KE,Clark EA

Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls.
Nature447(7145)661-78(2007 Jun)

Dendritic cell-associated lectin-1: a novel dendritic cell-associated, C-type lectin-like molecule enhances T cell secretion of IL-4.
Journal of immunology (Baltimore, Md. : 1950)169(10)5638-48(2002 Nov)
Ryan EJ,Marshall AJ,Magaletti D,Floyd H,Draves KE,Olson NE,Clark EA

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CLECL1 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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