VKORC1L1 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	VKORC1L1
Entrez Gene ID	154807
Full Name	vitamin K epoxide reductase complex subunit 1 like 1
General protein information	Preferred Names vitamin K epoxide reductase complex subunit 1 like 1 Names vitamin K epoxide reductase complex subunit 1-like protein 1 VKORC1-like protein 1
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 7 Map Location: 7q11.21
Summary	This gene encodes an enzyme important in the vitamin K cycle, which is involved in the carboxylation of glutamate residues present in vitamin K-dependent proteins. The encoded enzyme catalyzes the de-epoxidation of vitamin K 2,3-epoxide. Oxidative stress may upregulate expression of this gene and the encoded protein may protect cells and membrane proteins form oxidative damage. This gene and a related gene (Gene ID: 79001) may have arisen by gene duplication of an ancestral gene. [provided by RefSeq, Oct 2016].
Disorder MIM:	608838

mRNA and Protein(s)

mRNA	Protein	Name
XM_011515830.2	XP_011514132.1	vitamin K epoxide reductase complex subunit 1-like protein 1 isoform X1
XM_011515831.2	XP_011514133.1	vitamin K epoxide reductase complex subunit 1-like protein 1 isoform X2
NM_173517.6	NP_775788.2	vitamin K epoxide reductase complex subunit 1-like protein 1 isoform 1
NM_173517.5	NP_775788.2	vitamin K epoxide reductase complex subunit 1-like protein 1 isoform 1
NM_173517.4	NP_775788.2	vitamin K epoxide reductase complex subunit 1-like protein 1 isoform 1
XM_011515831.3	XP_011514133.1	vitamin K epoxide reductase complex subunit 1-like protein 1 isoform X1
NM_001284342.2	NP_001271271.1	vitamin K epoxide reductase complex subunit 1-like protein 1 isoform 2
NM_001284342.3	NP_001271271.1	vitamin K epoxide reductase complex subunit 1-like protein 1 isoform 2

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Vkorc1l1	NP_081397.1
Homo sapiens (human)	VKORC1L1	NP_775788.2
Pan troglodytes (chimpanzee)	VKORC1L1	XP_527770.2
	VKORC1L1	XP_001088069.1
Bos taurus (cattle)	VKORC1L1	XP_002698121.1
Rattus norvegicus (Norway rat)	Vkorc1l1	NP_976083.1
Xenopus tropicalis (tropical clawed frog)	vkorc1l1	NP_001016769.2
Canis lupus familiaris (dog)	VKORC1L1	XP_848485.1
Gallus gallus (chicken)	VKORC1L1	NP_001001328.1
Danio rerio (zebrafish)	vkorc1l1	NP_001018524.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP000543	XP_310541.3

Gene Ontology
Bibliography

Related articles in PubMed

Polymorphisms of vitamin K-related genes (EPHX1 and VKORC1L1) and stable warfarin doses.
Chung JE, Lee KE, Chang BC, Gwak HS
Gene64168-73(2018 Jan)

The membrane topology of vitamin K epoxide reductase is conserved between human isoforms and the bacterial enzyme.
Cao Z, van Lith M, Mitchell LJ, Pringle MA, Inaba K, Bulleid NJ
The Biochemical journal473(7)851-8(2016 Apr)

VKORC1 and VKORC1L1: Why do Vertebrates Have Two Vitamin K 2,3-Epoxide Reductases?
Oldenburg J, Watzka M, Bevans CG
Nutrients7(8)6250-80(2015 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

This study showed that polymorphisms of EPHX1 and VKORC1L1 could be determinants of stable warfarin doses.
Title: Polymorphisms of vitamin K-related genes (EPHX1 and VKORC1L1) and stable warfarin doses.

a concerted action of the four conserved cysteines of VKORC1L1 for active site regeneration
Title: Conserved loop cysteines of vitamin K epoxide reductase complex subunit 1-like 1 (VKORC1L1) are involved in its active site regeneration.

The involvement of VKORC1L1 in VKOR activity partly explains the low susceptibility of some extrahepatic tissues to vitamin K antagonists.
Title: VKORC1L1, an enzyme rescuing the vitamin K 2,3-epoxide reductase activity in some extrahepatic tissues during anticoagulation therapy.

VKORC1L1 is responsible for driving vitamin K-mediated intracellular antioxidation pathways critical to cell survival.
Title: Human vitamin K 2,3-epoxide reductase complex subunit 1-like 1 (VKORC1L1) mediates vitamin K-dependent intracellular antioxidant function.

Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)
Title: Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.

The following VKORC1L1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the VKORC1L1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu25660	NM_173517.6 Latest version!	Homo sapiens vitamin K epoxide reductase complex subunit 1 like 1 (VKORC1L1), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu25663	NM_001284342.3 Latest version!	Homo sapiens vitamin K epoxide reductase complex subunit 1 like 1 (VKORC1L1), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
OHu76865	XM_011515830.2 Latest version!	Homo sapiens vitamin K epoxide reductase complex subunit 1 like 1 (VKORC1L1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
OHu76866	XM_011515831.3 Latest version!	Homo sapiens vitamin K epoxide reductase complex subunit 1 like 1 (VKORC1L1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
View Old Accession Versions >>
OHu25660	NM_173517.5	Homo sapiens vitamin K epoxide reductase complex subunit 1 like 1 (VKORC1L1), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu25660	NM_173517.4	Homo sapiens vitamin K epoxide reductase complex, subunit 1-like 1 (VKORC1L1), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu76866	XM_011515831.2	Homo sapiens vitamin K epoxide reductase complex subunit 1 like 1 (VKORC1L1), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
OHu25663	NM_001284342.2	Homo sapiens vitamin K epoxide reductase complex subunit 1 like 1 (VKORC1L1), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
Hide Old Accession Versions >>

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***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

VKORC1L1 ( NM_173517.6 ) cDNA ORF clone, Homo sapiens(human) -> NP_775788.2 Homo sapiens vitamin K epoxide reductase complex subunit 1 like 1 (VKORC1L1), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu25660
Clone ID Related Accession (Same CDS sequence)	NM_173517.6 , NM_173517.5 , NM_173517.4
Accession Version	NM_173517.6 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 531bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-21
Organism	Homo sapiens(human)
Product	vitamin K epoxide reductase complex subunit 1-like protein 1 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC093582.3, HY064992.1, AK289522.1, AC073261.8 and BM991935.1. This sequence is a reference standard in the RefSeqGene project. On Nov 23, 2018 this sequence version replaced NM_173517.5. Transcript Variant: This variant (1) represents the longer transcript but encodes the shorter isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803612.245096.1, SRR1803617.280945.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## CDS uses downstream in-frame AUG :: community standard (PMID:26264021) MANE Ensembl match :: ENST00000360768.5/ ENSP00000353998.2 RefSeq Select criteria :: based on conservation, expression ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCGGCTC CCGTCCTGCT AAGAGTGTCG GTGCCGCGGT GGGAGCGGGT GGCCCGGTAT 
GCAGTGTGCG CTGCCGGAAT CCTGCTCTCC ATCTACGCCT ACCACGTGGA GCGGGAGAAG 
GAGCGGGACC CCGAGCACCG GGCCCTCTGC GACCTGGGGC CCTGGGTGAA GTGCTCCGCC 
GCCCTTGCCT CCAGATGGGG TCGAGGATTT GGTCTTTTGG GTTCCATTTT TGGAAAGGAT 
GGTGTATTAA ACCAGCCAAA CAGTGTCTTT GGACTTATAT TTTATATACT ACAGTTATTA 
CTTGGCATGA CAGCAAGCGC TGTGGCGGCT TTGATCCTCA TGACGTCCTC CATCATGTCG 
GTCGTGGGGT CCCTGTACCT GGCCTACATT CTGTACTTTG TGCTGAAGGA GTTCTGCATC 
ATCTGCATCG TCACGTACGT GCTGAACTTC CTTCTTCTCA TTATCAACTA CAAACGACTA 
GTTTACTTGA ACGAGGCCTG GAAGCGGCAG CTGCAACCCA AGCAGGACTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_775788.2
CDS	299..829
Translation	MAAPVLLRVSVPRWERVARYAVCAAGILLSIYAYHVEREKERDPEHRALCDLGPWVKCSAALASRWGRGFGLLGSIFGKDGVLNQPNSVFGLIFYILQLLLGMTASAVAALILMTSSIMSVVGSLYLAYILYFVLKEFCIICIVTYVLNFLLLIINYKRLVYLNEAWKRQLQPKQD

Target ORF information:

RefSeq Version	NM_173517.6
Organism	Homo sapiens(human)
Definition	Homo sapiens vitamin K epoxide reductase complex subunit 1 like 1 (VKORC1L1), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_173517.6

ORF Insert Sequence:

ATGGCGGCTC CCGTCCTGCT AAGAGTGTCG GTGCCGCGGT GGGAGCGGGT GGCCCGGTAT 
GCAGTGTGCG CTGCCGGAAT CCTGCTCTCC ATCTACGCCT ACCACGTGGA GCGGGAGAAG 
GAGCGGGACC CCGAGCACCG GGCCCTCTGC GACCTGGGGC CCTGGGTGAA GTGCTCCGCC 
GCCCTTGCCT CCAGATGGGG TCGAGGATTT GGTCTTTTGG GTTCCATTTT TGGAAAGGAT 
GGTGTATTAA ACCAGCCAAA CAGTGTCTTT GGACTTATAT TTTATATACT ACAGTTATTA 
CTTGGCATGA CAGCAAGCGC TGTGGCGGCT TTGATCCTCA TGACGTCCTC CATCATGTCG 
GTCGTGGGGT CCCTGTACCT GGCCTACATT CTGTACTTTG TGCTGAAGGA GTTCTGCATC 
ATCTGCATCG TCACGTACGT GCTGAACTTC CTTCTTCTCA TTATCAACTA CAAACGACTA 
GTTTACTTGA ACGAGGCCTG GAAGCGGCAG CTGCAACCCA AGCAGGACTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

VKORC1L1 ( NM_173517.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_775788.2 Homo sapiens vitamin K epoxide reductase complex subunit 1 like 1 (VKORC1L1), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu25660
Clone ID Related Accession (Same CDS sequence)	NM_173517.6 , NM_173517.5 , NM_173517.4
Accession Version	NM_173517.5	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 531bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-11-29
Organism	Homo sapiens(human)
Product	vitamin K epoxide reductase complex subunit 1-like protein 1 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from HY064992.1, AK289522.1, AC073261.8 and BM991935.1. This sequence is a reference standard in the RefSeqGene project. On Oct 22, 2016 this sequence version replaced NM_173517.4. Transcript Variant: This variant (1) represents the longer transcript but encodes the shorter isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803612.245096.1, SRR1803617.280945.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## CDS uses downstream in-frame AUG :: community standard (PMID:26264021) ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGCGGCTC CCGTCCTGCT AAGAGTGTCG GTGCCGCGGT GGGAGCGGGT GGCCCGGTAT 
GCAGTGTGCG CTGCCGGAAT CCTGCTCTCC ATCTACGCCT ACCACGTGGA GCGGGAGAAG 
GAGCGGGACC CCGAGCACCG GGCCCTCTGC GACCTGGGGC CCTGGGTGAA GTGCTCCGCC 
GCCCTTGCCT CCAGATGGGG TCGAGGATTT GGTCTTTTGG GTTCCATTTT TGGAAAGGAT 
GGTGTATTAA ACCAGCCAAA CAGTGTCTTT GGACTTATAT TTTATATACT ACAGTTATTA 
CTTGGCATGA CAGCAAGCGC TGTGGCGGCT TTGATCCTCA TGACGTCCTC CATCATGTCG 
GTCGTGGGGT CCCTGTACCT GGCCTACATT CTGTACTTTG TGCTGAAGGA GTTCTGCATC 
ATCTGCATCG TCACGTACGT GCTGAACTTC CTTCTTCTCA TTATCAACTA CAAACGACTA 
GTTTACTTGA ACGAGGCCTG GAAGCGGCAG CTGCAACCCA AGCAGGACTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_775788.2
CDS	274..804
Translation	MAAPVLLRVSVPRWERVARYAVCAAGILLSIYAYHVEREKERDPEHRALCDLGPWVKCSAALASRWGRGFGLLGSIFGKDGVLNQPNSVFGLIFYILQLLLGMTASAVAALILMTSSIMSVVGSLYLAYILYFVLKEFCIICIVTYVLNFLLLIINYKRLVYLNEAWKRQLQPKQD

Target ORF information:

RefSeq Version	NM_173517.5
Organism	Homo sapiens(human)
Definition	Homo sapiens vitamin K epoxide reductase complex subunit 1 like 1 (VKORC1L1), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_173517.5

ORF Insert Sequence:

ATGGCGGCTC CCGTCCTGCT AAGAGTGTCG GTGCCGCGGT GGGAGCGGGT GGCCCGGTAT 
GCAGTGTGCG CTGCCGGAAT CCTGCTCTCC ATCTACGCCT ACCACGTGGA GCGGGAGAAG 
GAGCGGGACC CCGAGCACCG GGCCCTCTGC GACCTGGGGC CCTGGGTGAA GTGCTCCGCC 
GCCCTTGCCT CCAGATGGGG TCGAGGATTT GGTCTTTTGG GTTCCATTTT TGGAAAGGAT 
GGTGTATTAA ACCAGCCAAA CAGTGTCTTT GGACTTATAT TTTATATACT ACAGTTATTA 
CTTGGCATGA CAGCAAGCGC TGTGGCGGCT TTGATCCTCA TGACGTCCTC CATCATGTCG 
GTCGTGGGGT CCCTGTACCT GGCCTACATT CTGTACTTTG TGCTGAAGGA GTTCTGCATC 
ATCTGCATCG TCACGTACGT GCTGAACTTC CTTCTTCTCA TTATCAACTA CAAACGACTA 
GTTTACTTGA ACGAGGCCTG GAAGCGGCAG CTGCAACCCA AGCAGGACTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

VKORC1L1 ( NM_173517.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_775788.2 Homo sapiens vitamin K epoxide reductase complex, subunit 1-like 1 (VKORC1L1), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu25660
Clone ID Related Accession (Same CDS sequence)	NM_173517.6 , NM_173517.5 , NM_173517.4
Accession Version	NM_173517.4	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 531bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-03-14
Organism	Homo sapiens(Human)
Product	vitamin K epoxide reductase complex subunit 1-like protein 1 isoform 1
Comment

ATGGCGGCTC CCGTCCTGCT AAGAGTGTCG GTGCCGCGGT GGGAGCGGGT GGCCCGGTAT 
GCAGTGTGCG CTGCCGGAAT CCTGCTCTCC ATCTACGCCT ACCACGTGGA GCGGGAGAAG 
GAGCGGGACC CCGAGCACCG GGCCCTCTGC GACCTGGGGC CCTGGGTGAA GTGCTCCGCC 
GCCCTTGCCT CCAGATGGGG TCGAGGATTT GGTCTTTTGG GTTCCATTTT TGGAAAGGAT 
GGTGTATTAA ACCAGCCAAA CAGTGTCTTT GGACTTATAT TTTATATACT ACAGTTATTA 
CTTGGCATGA CAGCAAGCGC TGTGGCGGCT TTGATCCTCA TGACGTCCTC CATCATGTCG 
GTCGTGGGGT CCCTGTACCT GGCCTACATT CTGTACTTTG TGCTGAAGGA GTTCTGCATC 
ATCTGCATCG TCACGTACGT GCTGAACTTC CTTCTTCTCA TTATCAACTA CAAACGACTA 
GTTTACTTGA ACGAGGCCTG GAAGCGGCAG CTGCAACCCA AGCAGGACTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_775788.2
Translation	MAAPVLLRVSVPRWERVARYAVCAAGILLSIYAYHVEREKERDPEHRALCDLGPWVKCSAALASRWGRGFGLLGSIFGKDGVLNQPNSVFGLIFYILQLLLGMTASAVAALILMTSSIMSVVGSLYLAYILYFVLKEFCIICIVTYVLNFLLLIINYKRLVYLNEAWKRQLQPKQD

Target ORF information:

RefSeq Version	NM_173517.4
Organism	Homo sapiens(Human)
Definition	Homo sapiens vitamin K epoxide reductase complex, subunit 1-like 1 (VKORC1L1), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_173517.4

ORF Insert Sequence:

ATGGCGGCTC CCGTCCTGCT AAGAGTGTCG GTGCCGCGGT GGGAGCGGGT GGCCCGGTAT 
GCAGTGTGCG CTGCCGGAAT CCTGCTCTCC ATCTACGCCT ACCACGTGGA GCGGGAGAAG 
GAGCGGGACC CCGAGCACCG GGCCCTCTGC GACCTGGGGC CCTGGGTGAA GTGCTCCGCC 
GCCCTTGCCT CCAGATGGGG TCGAGGATTT GGTCTTTTGG GTTCCATTTT TGGAAAGGAT 
GGTGTATTAA ACCAGCCAAA CAGTGTCTTT GGACTTATAT TTTATATACT ACAGTTATTA 
CTTGGCATGA CAGCAAGCGC TGTGGCGGCT TTGATCCTCA TGACGTCCTC CATCATGTCG 
GTCGTGGGGT CCCTGTACCT GGCCTACATT CTGTACTTTG TGCTGAAGGA GTTCTGCATC 
ATCTGCATCG TCACGTACGT GCTGAACTTC CTTCTTCTCA TTATCAACTA CAAACGACTA 
GTTTACTTGA ACGAGGCCTG GAAGCGGCAG CTGCAACCCA AGCAGGACTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

VKORC1L1 ( NM_001284342.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001271271.1 Homo sapiens vitamin K epoxide reductase complex subunit 1 like 1 (VKORC1L1), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu25663
Clone ID Related Accession (Same CDS sequence)	NM_001284342.2 , NM_001284342.3
Accession Version	NM_001284342.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 534bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-02
Organism	Homo sapiens(human)
Product	vitamin K epoxide reductase complex subunit 1-like protein 1 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from HY064992.1, AK304077.1, AC073261.8 and BM991935.1. On Oct 22, 2016 this sequence version replaced NM_001284342.1. Transcript Variant: This variant (2) lacks an in-frame exon in the central coding region compared to variant 1. The encoded isoform (2) is shorter than longer and has a distinct C-terminus compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803616.190639.1, AK304077.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## CDS uses downstream in-frame AUG :: community standard (PMID:26264021) ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGCGGCTC CCGTCCTGCT AAGAGTGTCG GTGCCGCGGT GGGAGCGGGT GGCCCGGTAT 
GCAGTGTGCG CTGCCGGAAT CCTGCTCTCC ATCTACGCCT ACCACGTGGA GCGGGAGAAG 
GAGCGGGACC CCGAGCACCG GGCCCTCTGC GACCTGGGGC CCTGGGTGAA GTGCTCCGCC 
GCCCTTGCCT CCAGGCATGA CAGCAAGCGC TGTGGCGGCT TTGATCCTCA TGACGTCCTC 
CATCATGTCG GTCGTGGGGT CCCTGTACCT GGCCTACATT CTGTACTTTG TGCTGAAGGA 
GTTCTGCATC ATCTGCATCG TCACGTACGT GCTGAACTTC CTTCTTCTCA TTATCAACTA 
CAAACGACTA GTTTACTTGA ACGAGGCCTG GAAGCGGCAG CTGCAACCCA AGCAGGACTG 
ACGCCCGACA GACTCCACCC TAACAGTCTC AAGCCCCTTT CCATTCAGTT TATTTTGCAG 
CAGGTTTTTA TTATTATTAT TATTATTATT ATTCACAACA GACACTTTCC CTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001271271.1
CDS	274..807
Translation	MAAPVLLRVSVPRWERVARYAVCAAGILLSIYAYHVEREKERDPEHRALCDLGPWVKCSAALASRHDSKRCGGFDPHDVLHHVGRGVPVPGLHSVLCAEGVLHHLHRHVRAELPSSHYQLQTTSLLERGLEAAAATQAGLTPDRLHPNSLKPLSIQFILQQVFIIIIIIIIHNRHFP

Target ORF information:

RefSeq Version	NM_001284342.2
Organism	Homo sapiens(human)
Definition	Homo sapiens vitamin K epoxide reductase complex subunit 1 like 1 (VKORC1L1), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001284342.2

ORF Insert Sequence:

ATGGCGGCTC CCGTCCTGCT AAGAGTGTCG GTGCCGCGGT GGGAGCGGGT GGCCCGGTAT 
GCAGTGTGCG CTGCCGGAAT CCTGCTCTCC ATCTACGCCT ACCACGTGGA GCGGGAGAAG 
GAGCGGGACC CCGAGCACCG GGCCCTCTGC GACCTGGGGC CCTGGGTGAA GTGCTCCGCC 
GCCCTTGCCT CCAGGCATGA CAGCAAGCGC TGTGGCGGCT TTGATCCTCA TGACGTCCTC 
CATCATGTCG GTCGTGGGGT CCCTGTACCT GGCCTACATT CTGTACTTTG TGCTGAAGGA 
GTTCTGCATC ATCTGCATCG TCACGTACGT GCTGAACTTC CTTCTTCTCA TTATCAACTA 
CAAACGACTA GTTTACTTGA ACGAGGCCTG GAAGCGGCAG CTGCAACCCA AGCAGGACTG 
ACGCCCGACA GACTCCACCC TAACAGTCTC AAGCCCCTTT CCATTCAGTT TATTTTGCAG 
CAGGTTTTTA TTATTATTAT TATTATTATT ATTCACAACA GACACTTTCC CTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

VKORC1L1 ( NM_001284342.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_001271271.1 Homo sapiens vitamin K epoxide reductase complex subunit 1 like 1 (VKORC1L1), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu25663
Clone ID Related Accession (Same CDS sequence)	NM_001284342.2 , NM_001284342.3
Accession Version	NM_001284342.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 534bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-28
Organism	Homo sapiens(human)
Product	vitamin K epoxide reductase complex subunit 1-like protein 1 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC093582.3, HY064992.1, AK304077.1, AC073261.8 and BM991935.1. On Jun 1, 2019 this sequence version replaced NM_001284342.2. Transcript Variant: This variant (2) lacks an in-frame exon in the central coding region compared to variant 1. The encoded isoform (2) is shorter than longer and has a distinct C-terminus compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803616.190639.1, SRR7346977.2626759.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## CDS uses downstream in-frame AUG :: community standard (PMID:26264021) ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGCGGCTC CCGTCCTGCT AAGAGTGTCG GTGCCGCGGT GGGAGCGGGT GGCCCGGTAT 
GCAGTGTGCG CTGCCGGAAT CCTGCTCTCC ATCTACGCCT ACCACGTGGA GCGGGAGAAG 
GAGCGGGACC CCGAGCACCG GGCCCTCTGC GACCTGGGGC CCTGGGTGAA GTGCTCCGCC 
GCCCTTGCCT CCAGGCATGA CAGCAAGCGC TGTGGCGGCT TTGATCCTCA TGACGTCCTC 
CATCATGTCG GTCGTGGGGT CCCTGTACCT GGCCTACATT CTGTACTTTG TGCTGAAGGA 
GTTCTGCATC ATCTGCATCG TCACGTACGT GCTGAACTTC CTTCTTCTCA TTATCAACTA 
CAAACGACTA GTTTACTTGA ACGAGGCCTG GAAGCGGCAG CTGCAACCCA AGCAGGACTG 
ACGCCCGACA GACTCCACCC TAACAGTCTC AAGCCCCTTT CCATTCAGTT TATTTTGCAG 
CAGGTTTTTA TTATTATTAT TATTATTATT ATTCACAACA GACACTTTCC CTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001271271.1
CDS	299..832
Translation	MAAPVLLRVSVPRWERVARYAVCAAGILLSIYAYHVEREKERDPEHRALCDLGPWVKCSAALASRHDSKRCGGFDPHDVLHHVGRGVPVPGLHSVLCAEGVLHHLHRHVRAELPSSHYQLQTTSLLERGLEAAAATQAGLTPDRLHPNSLKPLSIQFILQQVFIIIIIIIIHNRHFP

Target ORF information:

RefSeq Version	NM_001284342.3
Organism	Homo sapiens(human)
Definition	Homo sapiens vitamin K epoxide reductase complex subunit 1 like 1 (VKORC1L1), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001284342.3

ORF Insert Sequence:

ATGGCGGCTC CCGTCCTGCT AAGAGTGTCG GTGCCGCGGT GGGAGCGGGT GGCCCGGTAT 
GCAGTGTGCG CTGCCGGAAT CCTGCTCTCC ATCTACGCCT ACCACGTGGA GCGGGAGAAG 
GAGCGGGACC CCGAGCACCG GGCCCTCTGC GACCTGGGGC CCTGGGTGAA GTGCTCCGCC 
GCCCTTGCCT CCAGGCATGA CAGCAAGCGC TGTGGCGGCT TTGATCCTCA TGACGTCCTC 
CATCATGTCG GTCGTGGGGT CCCTGTACCT GGCCTACATT CTGTACTTTG TGCTGAAGGA 
GTTCTGCATC ATCTGCATCG TCACGTACGT GCTGAACTTC CTTCTTCTCA TTATCAACTA 
CAAACGACTA GTTTACTTGA ACGAGGCCTG GAAGCGGCAG CTGCAACCCA AGCAGGACTG 
ACGCCCGACA GACTCCACCC TAACAGTCTC AAGCCCCTTT CCATTCAGTT TATTTTGCAG 
CAGGTTTTTA TTATTATTAT TATTATTATT ATTCACAACA GACACTTTCC CTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

VKORC1L1 ( XM_011515830.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011514132.1 Homo sapiens vitamin K epoxide reductase complex subunit 1 like 1 (VKORC1L1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu76865
Clone ID Related Accession (Same CDS sequence)	XM_011515830.2
Accession Version	XM_011515830.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 495bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	vitamin K epoxide reductase complex subunit 1-like protein 1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000007.14) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011515830.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCACTTCA GCAGGGGTCC CCAACCCCTG AGCCATGGAG CTGTAAGGAG CCACACAGCA 
GGAGCCTGCC GCTTCTTACC AAGAGGTGCA AGTGGACAGG AAATGATGTC TCCAGCCAAC 
AGCCAGAGAG GACCTCAGGC CTGCCAGCAG CAGTGGAAAT GGGGTCGAGG ATTTGGTCTT 
TTGGGTTCCA TTTTTGGAAA GGATGGTGTA TTAAACCAGC CAAACAGTGT CTTTGGACTT 
ATATTTTATA TACTACAGTT ATTACTTGGC ATGACAGCAA GCGCTGTGGC GGCTTTGATC 
CTCATGACGT CCTCCATCAT GTCGGTCGTG GGGTCCCTGT ACCTGGCCTA CATTCTGTAC 
TTTGTGCTGA AGGAGTTCTG CATCATCTGC ATCGTCACGT ACGTGCTGAA CTTCCTTCTT 
CTCATTATCA ACTACAAACG ACTAGTTTAC TTGAACGAGG CCTGGAAGCG GCAGCTGCAA 
CCCAAGCAGG ACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011514132.1
CDS	1935..2429
Translation	MHFSRGPQPLSHGAVRSHTAGACRFLPRGASGQEMMSPANSQRGPQACQQQWKWGRGFGLLGSIFGKDGVLNQPNSVFGLIFYILQLLLGMTASAVAALILMTSSIMSVVGSLYLAYILYFVLKEFCIICIVTYVLNFLLLIINYKRLVYLNEAWKRQLQPKQD

Target ORF information:

RefSeq Version	XM_011515830.2
Organism	Homo sapiens(human)
Definition	Homo sapiens vitamin K epoxide reductase complex subunit 1 like 1 (VKORC1L1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011515830.2

ORF Insert Sequence:

ATGCACTTCA GCAGGGGTCC CCAACCCCTG AGCCATGGAG CTGTAAGGAG CCACACAGCA 
GGAGCCTGCC GCTTCTTACC AAGAGGTGCA AGTGGACAGG AAATGATGTC TCCAGCCAAC 
AGCCAGAGAG GACCTCAGGC CTGCCAGCAG CAGTGGAAAT GGGGTCGAGG ATTTGGTCTT 
TTGGGTTCCA TTTTTGGAAA GGATGGTGTA TTAAACCAGC CAAACAGTGT CTTTGGACTT 
ATATTTTATA TACTACAGTT ATTACTTGGC ATGACAGCAA GCGCTGTGGC GGCTTTGATC 
CTCATGACGT CCTCCATCAT GTCGGTCGTG GGGTCCCTGT ACCTGGCCTA CATTCTGTAC 
TTTGTGCTGA AGGAGTTCTG CATCATCTGC ATCGTCACGT ACGTGCTGAA CTTCCTTCTT 
CTCATTATCA ACTACAAACG ACTAGTTTAC TTGAACGAGG CCTGGAAGCG GCAGCTGCAA 
CCCAAGCAGG ACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

VKORC1L1 ( XM_011515831.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011514133.1 Homo sapiens vitamin K epoxide reductase complex subunit 1 like 1 (VKORC1L1), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu76866
Clone ID Related Accession (Same CDS sequence)	XM_011515831.2 , XM_011515831.3
Accession Version	XM_011515831.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 444bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	vitamin K epoxide reductase complex subunit 1-like protein 1 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000007.14) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011515831.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGATGAAAC AAGCCTGCCG CTTCTTACCA AGAGGTGCAA GTGGACAGGA AATGATGTCT 
CCAGCCAACA GCCAGAGAGG ACCTCAGGCC TGCCAGCAGC AGTGGAAATG GGGTCGAGGA 
TTTGGTCTTT TGGGTTCCAT TTTTGGAAAG GATGGTGTAT TAAACCAGCC AAACAGTGTC 
TTTGGACTTA TATTTTATAT ACTACAGTTA TTACTTGGCA TGACAGCAAG CGCTGTGGCG 
GCTTTGATCC TCATGACGTC CTCCATCATG TCGGTCGTGG GGTCCCTGTA CCTGGCCTAC 
ATTCTGTACT TTGTGCTGAA GGAGTTCTGC ATCATCTGCA TCGTCACGTA CGTGCTGAAC 
TTCCTTCTTC TCATTATCAA CTACAAACGA CTAGTTTACT TGAACGAGGC CTGGAAGCGG 
CAGCTGCAAC CCAAGCAGGA CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011514133.1
CDS	16..459
Translation	MMKQACRFLPRGASGQEMMSPANSQRGPQACQQQWKWGRGFGLLGSIFGKDGVLNQPNSVFGLIFYILQLLLGMTASAVAALILMTSSIMSVVGSLYLAYILYFVLKEFCIICIVTYVLNFLLLIINYKRLVYLNEAWKRQLQPKQD

Target ORF information:

RefSeq Version	XM_011515831.2
Organism	Homo sapiens(human)
Definition	Homo sapiens vitamin K epoxide reductase complex subunit 1 like 1 (VKORC1L1), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011515831.2

ORF Insert Sequence:

ATGATGAAAC AAGCCTGCCG CTTCTTACCA AGAGGTGCAA GTGGACAGGA AATGATGTCT 
CCAGCCAACA GCCAGAGAGG ACCTCAGGCC TGCCAGCAGC AGTGGAAATG GGGTCGAGGA 
TTTGGTCTTT TGGGTTCCAT TTTTGGAAAG GATGGTGTAT TAAACCAGCC AAACAGTGTC 
TTTGGACTTA TATTTTATAT ACTACAGTTA TTACTTGGCA TGACAGCAAG CGCTGTGGCG 
GCTTTGATCC TCATGACGTC CTCCATCATG TCGGTCGTGG GGTCCCTGTA CCTGGCCTAC 
ATTCTGTACT TTGTGCTGAA GGAGTTCTGC ATCATCTGCA TCGTCACGTA CGTGCTGAAC 
TTCCTTCTTC TCATTATCAA CTACAAACGA CTAGTTTACT TGAACGAGGC CTGGAAGCGG 
CAGCTGCAAC CCAAGCAGGA CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

VKORC1L1 ( XM_011515831.3 ) cDNA ORF clone, Homo sapiens(human) -> XP_011514133.1 Homo sapiens vitamin K epoxide reductase complex subunit 1 like 1 (VKORC1L1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu76866
Clone ID Related Accession (Same CDS sequence)	XM_011515831.2 , XM_011515831.3
Accession Version	XM_011515831.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 444bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	vitamin K epoxide reductase complex subunit 1-like protein 1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000007.14) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_011515831.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGATGAAAC AAGCCTGCCG CTTCTTACCA AGAGGTGCAA GTGGACAGGA AATGATGTCT 
CCAGCCAACA GCCAGAGAGG ACCTCAGGCC TGCCAGCAGC AGTGGAAATG GGGTCGAGGA 
TTTGGTCTTT TGGGTTCCAT TTTTGGAAAG GATGGTGTAT TAAACCAGCC AAACAGTGTC 
TTTGGACTTA TATTTTATAT ACTACAGTTA TTACTTGGCA TGACAGCAAG CGCTGTGGCG 
GCTTTGATCC TCATGACGTC CTCCATCATG TCGGTCGTGG GGTCCCTGTA CCTGGCCTAC 
ATTCTGTACT TTGTGCTGAA GGAGTTCTGC ATCATCTGCA TCGTCACGTA CGTGCTGAAC 
TTCCTTCTTC TCATTATCAA CTACAAACGA CTAGTTTACT TGAACGAGGC CTGGAAGCGG 
CAGCTGCAAC CCAAGCAGGA CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011514133.1
CDS	16..459
Translation	MMKQACRFLPRGASGQEMMSPANSQRGPQACQQQWKWGRGFGLLGSIFGKDGVLNQPNSVFGLIFYILQLLLGMTASAVAALILMTSSIMSVVGSLYLAYILYFVLKEFCIICIVTYVLNFLLLIINYKRLVYLNEAWKRQLQPKQD

Target ORF information:

RefSeq Version	XM_011515831.3
Organism	Homo sapiens(human)
Definition	Homo sapiens vitamin K epoxide reductase complex subunit 1 like 1 (VKORC1L1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011515831.3

ORF Insert Sequence:

ATGATGAAAC AAGCCTGCCG CTTCTTACCA AGAGGTGCAA GTGGACAGGA AATGATGTCT 
CCAGCCAACA GCCAGAGAGG ACCTCAGGCC TGCCAGCAGC AGTGGAAATG GGGTCGAGGA 
TTTGGTCTTT TGGGTTCCAT TTTTGGAAAG GATGGTGTAT TAAACCAGCC AAACAGTGTC 
TTTGGACTTA TATTTTATAT ACTACAGTTA TTACTTGGCA TGACAGCAAG CGCTGTGGCG 
GCTTTGATCC TCATGACGTC CTCCATCATG TCGGTCGTGG GGTCCCTGTA CCTGGCCTAC 
ATTCTGTACT TTGTGCTGAA GGAGTTCTGC ATCATCTGCA TCGTCACGTA CGTGCTGAAC 
TTCCTTCTTC TCATTATCAA CTACAAACGA CTAGTTTACT TGAACGAGGC CTGGAAGCGG 
CAGCTGCAAC CCAAGCAGGA CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Polymorphisms of vitamin K-related genes (EPHX1 and VKORC1L1) and stable warfarin doses.
Gene64168-73(2018 Jan)
Chung JE,Lee KE,Chang BC,Gwak HS

The membrane topology of vitamin K epoxide reductase is conserved between human isoforms and the bacterial enzyme.
The Biochemical journal473(7)851-8(2016 Apr)
Cao Z,van Lith M,Mitchell LJ,Pringle MA,Inaba K,Bulleid NJ

VKORC1 and VKORC1L1: Why do Vertebrates Have Two Vitamin K 2,3-Epoxide Reductases?
Nutrients7(8)6250-80(2015 Jul)
Oldenburg J,Watzka M,Bevans CG

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VKORC1L1 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

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ORF Insert Sequence:

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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FAX

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