| Gene Symbol | CX3CR1 |
| Entrez Gene ID | 1524 |
| Full Name | C-X3-C motif chemokine receptor 1 |
| Synonyms | CCRL1,CMKBRL1,CMKDR1,GPR13,GPRV28,V28 |
| General protein information |
|
| Gene Type | protein-coding |
| Organism | Homo sapiens(human) |
| Genome | |
| Summary | Fractalkine is a transmembrane protein and chemokine involved in the adhesion and migration of leukocytes. The protein encoded by this gene is a receptor for fractalkine. The encoded protein also is a coreceptor for HIV-1, and some variations in this gene lead to increased susceptibility to HIV-1 infection and rapid progression to AIDS. Four transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jan 2010]. |
| Disorder MIM: | |
| Disorder Html: | {Rapid progression to AIDS from HIV1 infection}, 609423 (3); {Coronary artery disease, resistance to}, 607339 (3); {Macular degeneration, age-related, 12}, 613784 (3) |








































User Manual