DMBX1 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	DMBX1
Entrez Gene ID	127343
Full Name	diencephalon/mesencephalon homeobox 1
Synonyms	MBX,OTX3,PAXB
General protein information	Preferred Names diencephalon/mesencephalon homeobox 1 Names diencephalon/mesencephalon homeobox protein 1 homeoprotein MBX orthodenticle homolog 3 paired-like homeobox protein DMBX1
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 1 Map Location: 1p33
Summary	This gene encodes a member of the bicoid sub-family of homeodomain-containing transcription factors. The encoded protein acts as a transcription factor and may play a role in brain and sensory organ development. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008].
Disorder MIM:	607410

mRNA and Protein(s)

mRNA	Protein	Name
NM_147192.2	NP_671725.1	diencephalon/mesencephalon homeobox protein 1 isoform b
XM_011540668.2	XP_011538970.1	diencephalon/mesencephalon homeobox protein 1 isoform X1
XM_017000289.1	XP_016855778.1	diencephalon/mesencephalon homeobox protein 1 isoform X1
NM_147192.3	NP_671725.1	diencephalon/mesencephalon homeobox protein 1 isoform b
NM_172225.2	NP_757379.1	diencephalon/mesencephalon homeobox protein 1 isoform a
NM_172225.1	NP_757379.1	diencephalon/mesencephalon homeobox protein 1 isoform a

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Dmbx1	NP_570935.3
	DMBX1	XP_001098052.2
Homo sapiens (human)	DMBX1	NP_671725.1
Rattus norvegicus (Norway rat)	Dmbx1	NP_001101431.1
Danio rerio (zebrafish)	dmbx1b	NP_001017625.1
Xenopus tropicalis (tropical clawed frog)	LOC100493907	XP_002931450.2
Gallus gallus (chicken)	DMBX1	XP_001234036.1

Gene Ontology
Bibliography

Related articles in PubMed

Epigenome-wide association data implicates DNA methylation-mediated genetic risk in psoriasis.
Zhou F, Shen C, Xu J, Gao J, Zheng X, Ko R, Dou J, Cheng Y, Zhu C, Xu S, Tang X, Zuo X, Yin X, Cui Y, Sun L, Tsoi LC, Hsu YH, Yang S, Zhang X
Clinical epigenetics8131(2016)

An atlas of genetic influences on human blood metabolites.
Shin SY, Fauman EB, Petersen AK, Krumsiek J, Santos R, Huang J, Arnold M, Erte I, Forgetta V, Yang TP, Walter K, Menni C, Chen L, Vasquez L, Valdes AM, Hyde CL, Wang V, Ziemek D, Roberts P, Xi L, Grundberg E, , Waldenberger M, Richards JB, Mohney RP, Milburn MV, John SL, Trimmer J, Theis FJ, Overington JP, Suhre K, Brosnan MJ, Gieger C, Kastenm?ller G, Spector TD, Soranzo N
Nature genetics46(6)543-550(2014 Jun)

A census of human transcription factors: function, expression and evolution.
Vaquerizas JM, Kummerfeld SK, Teichmann SA, Luscombe NM
Nature reviews. Genetics10(4)252-63(2009 04)

Mutational analysis of the human MBX gene in four Korean families demonstrating microphthalmia with congenital cataract.
Miyamoto T, Yu YS, Sato H, Hayashi H, Sakugawa N, Ishikawa M, Sengoku K
The Turkish journal of pediatrics49(3)334-6(2007 Jul-Sep)

The homeobox gene mbx is involved in eye and tectum development.
Kawahara A, Chien CB, Dawid IB
Developmental biology248(1)107-17(2002 Aug)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Results found that CpG sites of C1orf106, DMBX1, and SIK3 mediate the genetic risk of psoriasis in Chinese Han population.
Title: Epigenome-wide association data implicates DNA methylation-mediated genetic risk in psoriasis.

no indications were found for an association between the MBX gene and microphthalmia with congenital cataract in humans
Title: Mutational analysis of the human MBX gene in four Korean families demonstrating microphthalmia with congenital cataract.

The following DMBX1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the DMBX1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu10203	NM_172225.2 Latest version!	Homo sapiens diencephalon/mesencephalon homeobox 1 (DMBX1), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
OHu10203	XM_017000289.1 Latest version!	Homo sapiens diencephalon/mesencephalon homeobox 1 (DMBX1), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
OHu10203	XM_011540668.2 Latest version!	Homo sapiens diencephalon/mesencephalon homeobox 1 (DMBX1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
OHu10423	NM_147192.3 Latest version!	Homo sapiens diencephalon/mesencephalon homeobox 1 (DMBX1), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
View Old Accession Versions >>
OHu10423	NM_147192.2	Homo sapiens diencephalon/mesencephalon homeobox 1 (DMBX1), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
OHu10203	NM_172225.1	Homo sapiens diencephalon/mesencephalon homeobox 1 (DMBX1), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

DMBX1 ( NM_172225.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_757379.1 Homo sapiens diencephalon/mesencephalon homeobox 1 (DMBX1), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu10203
Clone ID Related Accession (Same CDS sequence)	XM_011540668.2 , XM_017000289.1 , NM_172225.2 , NM_172225.1
Accession Version	NM_172225.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1134bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-21
Organism	Homo sapiens(human)
Product	diencephalon/mesencephalon homeobox protein 1 isoform a
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL137797.9. This sequence is a reference standard in the RefSeqGene project. On May 9, 2019 this sequence version replaced NM_172225.1. Transcript Variant: This variant (1) represents the longer transcript and encodes the shorter isoform (a). Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## CDS exon combination :: AF398527.1 [ECO:0000331] RNAseq introns :: single sample supports all introns SAMEA2158188 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on conservation, expression ##RefSeq-Attributes-END##

ATGCAGCACT ACGGGGTGAA CGGCTACTCA CTGCACGCCA TGAACTCACT CAGCGCCATG 
TACAACCTGC ACCAGCAGGC AGCCCAGCAG GCCCAGCATG CCCCCGACTA CCGGCCTTCA 
GTGCATGCGC TTACATTGGC TGAGCGCCTG GCTGACATCA TCTTGGAGGC CCGTTATGGT 
TCCCAGCACC GCAAACAACG TCGCAGCCGC ACAGCGTTCA CGGCTCAGCA GCTCGAGGCC 
CTGGAAAAGA CCTTCCAGAA GACTCACTAC CCAGATGTGG TGATGCGTGA GAGGCTGGCC 
ATGTGCACCA ACCTGCCTGA GGCCCGGGTG CAGGTGTGGT TCAAGAACCG CCGGGCCAAG 
TTCCGGAAGA AGCAGCGTAG CCTGCAGAAG GAACAGCTCC AGAAGCAGAA GGAGGCTGAG 
GGCTCCCATG GGGAAGGCAA GGCCGAGGCC CCCACTCCAG ATACCCAGCT GGACACTGAG 
CAGCCCCCAC GTCTGCCTGG CAGCGACCCC CCTGCTGAGC TTCACCTGAG TCTGTCTGAG 
CAGTCAGCCA GTGAGTCAGC CCCCGAGGAT CAGCCGGACC GTGAGGAGGA CCCCAGGGCA 
GGGGCTGAGG ACCCCAAAGC TGAGAAGAGC CCTGGGGCTG ACAGCAAGGG GCTGGGCTGC 
AAGAGGGGCA GCCCCAAGGC AGATTCCCCA GGCAGCCTGA CCATCACTCC TGTGGCCCCA 
GGGGGTGGCC TCCTGGGCCC CTCCCACTCC TATTCCTCGT CCCCGCTGAG CCTCTTCCGT 
CTGCAGGAGC AATTCCGCCA GCACATGGCG GCCACCAACA ACCTGGTGCA CTACTCGTCC 
TTCGAAGTAG GGGGTCCGGC CCCTGCTGCT GCAGCGGCGG CTGCTGCTGT GCCCTACCTG 
GGCGTCAACA TGGCCCCGCT GGGCTCACTG CACTGCCAGT CCTACTACCA GTCCCTGTCA 
GCAGCCGCTG CTGCCCACCA GGGTGTGTGG GGGTCTCCTC TGCTGCCTGC ACCCCCAGCA 
GGCCTGGCTC CTGCATCAGC TACCCTGAAC AGTAAAACCA CAAGCATCGA GAACCTGCGG 
CTCCGGGCCA AGCAGCACGC GGCCTCCCTG GGACTCGATA CGCTGCCCAA CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_757379.1
CDS	195..1328
Translation	MQHYGVNGYSLHAMNSLSAMYNLHQQAAQQAQHAPDYRPSVHALTLAERLADIILEARYGSQHRKQRRSRTAFTAQQLEALEKTFQKTHYPDVVMRERLAMCTNLPEARVQVWFKNRRAKFRKKQRSLQKEQLQKQKEAEGSHGEGKAEAPTPDTQLDTEQPPRLPGSDPPAELHLSLSEQSASESAPEDQPDREEDPRAGAEDPKAEKSPGADSKGLGCKRGSPKADSPGSLTITPVAPGGGLLGPSHSYSSSPLSLFRLQEQFRQHMAATNNLVHYSSFEVGGPAPAAAAAAAAVPYLGVNMAPLGSLHCQSYYQSLSAAAAAHQGVWGSPLLPAPPAGLAPASATLNSKTTSIENLRLRAKQHAASLGLDTLPN

Target ORF information:

RefSeq Version	NM_172225.2
Organism	Homo sapiens(human)
Definition	Homo sapiens diencephalon/mesencephalon homeobox 1 (DMBX1), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_172225.2

ORF Insert Sequence:

ATGCAGCACT ACGGGGTGAA CGGCTACTCA CTGCACGCCA TGAACTCACT CAGCGCCATG 
TACAACCTGC ACCAGCAGGC AGCCCAGCAG GCCCAGCATG CCCCCGACTA CCGGCCTTCA 
GTGCATGCGC TTACATTGGC TGAGCGCCTG GCTGACATCA TCTTGGAGGC CCGTTATGGT 
TCCCAGCACC GCAAACAACG TCGCAGCCGC ACAGCGTTCA CGGCTCAGCA GCTCGAGGCC 
CTGGAAAAGA CCTTCCAGAA GACTCACTAC CCAGATGTGG TGATGCGTGA GAGGCTGGCC 
ATGTGCACCA ACCTGCCTGA GGCCCGGGTG CAGGTGTGGT TCAAGAACCG CCGGGCCAAG 
TTCCGGAAGA AGCAGCGTAG CCTGCAGAAG GAACAGCTCC AGAAGCAGAA GGAGGCTGAG 
GGCTCCCATG GGGAAGGCAA GGCCGAGGCC CCCACTCCAG ATACCCAGCT GGACACTGAG 
CAGCCCCCAC GTCTGCCTGG CAGCGACCCC CCTGCTGAGC TTCACCTGAG TCTGTCTGAG 
CAGTCAGCCA GTGAGTCAGC CCCCGAGGAT CAGCCGGACC GTGAGGAGGA CCCCAGGGCA 
GGGGCTGAGG ACCCCAAAGC TGAGAAGAGC CCTGGGGCTG ACAGCAAGGG GCTGGGCTGC 
AAGAGGGGCA GCCCCAAGGC AGATTCCCCA GGCAGCCTGA CCATCACTCC TGTGGCCCCA 
GGGGGTGGCC TCCTGGGCCC CTCCCACTCC TATTCCTCGT CCCCGCTGAG CCTCTTCCGT 
CTGCAGGAGC AATTCCGCCA GCACATGGCG GCCACCAACA ACCTGGTGCA CTACTCGTCC 
TTCGAAGTAG GGGGTCCGGC CCCTGCTGCT GCAGCGGCGG CTGCTGCTGT GCCCTACCTG 
GGCGTCAACA TGGCCCCGCT GGGCTCACTG CACTGCCAGT CCTACTACCA GTCCCTGTCA 
GCAGCCGCTG CTGCCCACCA GGGTGTGTGG GGGTCTCCTC TGCTGCCTGC ACCCCCAGCA 
GGCCTGGCTC CTGCATCAGC TACCCTGAAC AGTAAAACCA CAAGCATCGA GAACCTGCGG 
CTCCGGGCCA AGCAGCACGC GGCCTCCCTG GGACTCGATA CGCTGCCCAA CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

DMBX1 ( NM_172225.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_757379.1 Homo sapiens diencephalon/mesencephalon homeobox 1 (DMBX1), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu10203
Clone ID Related Accession (Same CDS sequence)	XM_011540668.2 , XM_017000289.1 , NM_172225.2 , NM_172225.1
Accession Version	NM_172225.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1134bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-06-22
Organism	Homo sapiens(human)
Product	diencephalon/mesencephalon homeobox protein 1 isoform a
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL137797.9. This sequence is a reference standard in the RefSeqGene project. Transcript Variant: This variant (1) represents the shorter transcript and encodes the shorter isoform (a). Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: AB037699.1, AF398527.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2148093 [ECO:0000348] ##Evidence-Data-END##

ATGCAGCACT ACGGGGTGAA CGGCTACTCA CTGCACGCCA TGAACTCACT CAGCGCCATG 
TACAACCTGC ACCAGCAGGC AGCCCAGCAG GCCCAGCATG CCCCCGACTA CCGGCCTTCA 
GTGCATGCGC TTACATTGGC TGAGCGCCTG GCTGACATCA TCTTGGAGGC CCGTTATGGT 
TCCCAGCACC GCAAACAACG TCGCAGCCGC ACAGCGTTCA CGGCTCAGCA GCTCGAGGCC 
CTGGAAAAGA CCTTCCAGAA GACTCACTAC CCAGATGTGG TGATGCGTGA GAGGCTGGCC 
ATGTGCACCA ACCTGCCTGA GGCCCGGGTG CAGGTGTGGT TCAAGAACCG CCGGGCCAAG 
TTCCGGAAGA AGCAGCGTAG CCTGCAGAAG GAACAGCTCC AGAAGCAGAA GGAGGCTGAG 
GGCTCCCATG GGGAAGGCAA GGCCGAGGCC CCCACTCCAG ATACCCAGCT GGACACTGAG 
CAGCCCCCAC GTCTGCCTGG CAGCGACCCC CCTGCTGAGC TTCACCTGAG TCTGTCTGAG 
CAGTCAGCCA GTGAGTCAGC CCCCGAGGAT CAGCCGGACC GTGAGGAGGA CCCCAGGGCA 
GGGGCTGAGG ACCCCAAAGC TGAGAAGAGC CCTGGGGCTG ACAGCAAGGG GCTGGGCTGC 
AAGAGGGGCA GCCCCAAGGC AGATTCCCCA GGCAGCCTGA CCATCACTCC TGTGGCCCCA 
GGGGGTGGCC TCCTGGGCCC CTCCCACTCC TATTCCTCGT CCCCGCTGAG CCTCTTCCGT 
CTGCAGGAGC AATTCCGCCA GCACATGGCG GCCACCAACA ACCTGGTGCA CTACTCGTCC 
TTCGAAGTAG GGGGTCCGGC CCCTGCTGCT GCAGCGGCGG CTGCTGCTGT GCCCTACCTG 
GGCGTCAACA TGGCCCCGCT GGGCTCACTG CACTGCCAGT CCTACTACCA GTCCCTGTCA 
GCAGCCGCTG CTGCCCACCA GGGTGTGTGG GGGTCTCCTC TGCTGCCTGC ACCCCCAGCA 
GGCCTGGCTC CTGCATCAGC TACCCTGAAC AGTAAAACCA CAAGCATCGA GAACCTGCGG 
CTCCGGGCCA AGCAGCACGC GGCCTCCCTG GGACTCGATA CGCTGCCCAA CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_757379.1
CDS	16..1149
Translation	MQHYGVNGYSLHAMNSLSAMYNLHQQAAQQAQHAPDYRPSVHALTLAERLADIILEARYGSQHRKQRRSRTAFTAQQLEALEKTFQKTHYPDVVMRERLAMCTNLPEARVQVWFKNRRAKFRKKQRSLQKEQLQKQKEAEGSHGEGKAEAPTPDTQLDTEQPPRLPGSDPPAELHLSLSEQSASESAPEDQPDREEDPRAGAEDPKAEKSPGADSKGLGCKRGSPKADSPGSLTITPVAPGGGLLGPSHSYSSSPLSLFRLQEQFRQHMAATNNLVHYSSFEVGGPAPAAAAAAAAVPYLGVNMAPLGSLHCQSYYQSLSAAAAAHQGVWGSPLLPAPPAGLAPASATLNSKTTSIENLRLRAKQHAASLGLDTLPN

Target ORF information:

RefSeq Version	NM_172225.1
Organism	Homo sapiens(human)
Definition	Homo sapiens diencephalon/mesencephalon homeobox 1 (DMBX1), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_172225.1

ORF Insert Sequence:

ATGCAGCACT ACGGGGTGAA CGGCTACTCA CTGCACGCCA TGAACTCACT CAGCGCCATG 
TACAACCTGC ACCAGCAGGC AGCCCAGCAG GCCCAGCATG CCCCCGACTA CCGGCCTTCA 
GTGCATGCGC TTACATTGGC TGAGCGCCTG GCTGACATCA TCTTGGAGGC CCGTTATGGT 
TCCCAGCACC GCAAACAACG TCGCAGCCGC ACAGCGTTCA CGGCTCAGCA GCTCGAGGCC 
CTGGAAAAGA CCTTCCAGAA GACTCACTAC CCAGATGTGG TGATGCGTGA GAGGCTGGCC 
ATGTGCACCA ACCTGCCTGA GGCCCGGGTG CAGGTGTGGT TCAAGAACCG CCGGGCCAAG 
TTCCGGAAGA AGCAGCGTAG CCTGCAGAAG GAACAGCTCC AGAAGCAGAA GGAGGCTGAG 
GGCTCCCATG GGGAAGGCAA GGCCGAGGCC CCCACTCCAG ATACCCAGCT GGACACTGAG 
CAGCCCCCAC GTCTGCCTGG CAGCGACCCC CCTGCTGAGC TTCACCTGAG TCTGTCTGAG 
CAGTCAGCCA GTGAGTCAGC CCCCGAGGAT CAGCCGGACC GTGAGGAGGA CCCCAGGGCA 
GGGGCTGAGG ACCCCAAAGC TGAGAAGAGC CCTGGGGCTG ACAGCAAGGG GCTGGGCTGC 
AAGAGGGGCA GCCCCAAGGC AGATTCCCCA GGCAGCCTGA CCATCACTCC TGTGGCCCCA 
GGGGGTGGCC TCCTGGGCCC CTCCCACTCC TATTCCTCGT CCCCGCTGAG CCTCTTCCGT 
CTGCAGGAGC AATTCCGCCA GCACATGGCG GCCACCAACA ACCTGGTGCA CTACTCGTCC 
TTCGAAGTAG GGGGTCCGGC CCCTGCTGCT GCAGCGGCGG CTGCTGCTGT GCCCTACCTG 
GGCGTCAACA TGGCCCCGCT GGGCTCACTG CACTGCCAGT CCTACTACCA GTCCCTGTCA 
GCAGCCGCTG CTGCCCACCA GGGTGTGTGG GGGTCTCCTC TGCTGCCTGC ACCCCCAGCA 
GGCCTGGCTC CTGCATCAGC TACCCTGAAC AGTAAAACCA CAAGCATCGA GAACCTGCGG 
CTCCGGGCCA AGCAGCACGC GGCCTCCCTG GGACTCGATA CGCTGCCCAA CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

DMBX1 ( XM_011540668.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011538970.1 Homo sapiens diencephalon/mesencephalon homeobox 1 (DMBX1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu10203
Clone ID Related Accession (Same CDS sequence)	XM_011540668.2 , XM_017000289.1 , NM_172225.2 , NM_172225.1
Accession Version	XM_011540668.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1134bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	diencephalon/mesencephalon homeobox protein 1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000001.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011540668.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCAGCACT ACGGGGTGAA CGGCTACTCA CTGCACGCCA TGAACTCACT CAGCGCCATG 
TACAACCTGC ACCAGCAGGC AGCCCAGCAG GCCCAGCATG CCCCCGACTA CCGGCCTTCA 
GTGCATGCGC TTACATTGGC TGAGCGCCTG GCTGACATCA TCTTGGAGGC CCGTTATGGT 
TCCCAGCACC GCAAACAACG TCGCAGCCGC ACAGCGTTCA CGGCTCAGCA GCTCGAGGCC 
CTGGAAAAGA CCTTCCAGAA GACTCACTAC CCAGATGTGG TGATGCGTGA GAGGCTGGCC 
ATGTGCACCA ACCTGCCTGA GGCCCGGGTG CAGGTGTGGT TCAAGAACCG CCGGGCCAAG 
TTCCGGAAGA AGCAGCGTAG CCTGCAGAAG GAACAGCTCC AGAAGCAGAA GGAGGCTGAG 
GGCTCCCATG GGGAAGGCAA GGCCGAGGCC CCCACTCCAG ATACCCAGCT GGACACTGAG 
CAGCCCCCAC GTCTGCCTGG CAGCGACCCC CCTGCTGAGC TTCACCTGAG TCTGTCTGAG 
CAGTCAGCCA GTGAGTCAGC CCCCGAGGAT CAGCCGGACC GTGAGGAGGA CCCCAGGGCA 
GGGGCTGAGG ACCCCAAAGC TGAGAAGAGC CCTGGGGCTG ACAGCAAGGG GCTGGGCTGC 
AAGAGGGGCA GCCCCAAGGC AGATTCCCCA GGCAGCCTGA CCATCACTCC TGTGGCCCCA 
GGGGGTGGCC TCCTGGGCCC CTCCCACTCC TATTCCTCGT CCCCGCTGAG CCTCTTCCGT 
CTGCAGGAGC AATTCCGCCA GCACATGGCG GCCACCAACA ACCTGGTGCA CTACTCGTCC 
TTCGAAGTAG GGGGTCCGGC CCCTGCTGCT GCAGCGGCGG CTGCTGCTGT GCCCTACCTG 
GGCGTCAACA TGGCCCCGCT GGGCTCACTG CACTGCCAGT CCTACTACCA GTCCCTGTCA 
GCAGCCGCTG CTGCCCACCA GGGTGTGTGG GGGTCTCCTC TGCTGCCTGC ACCCCCAGCA 
GGCCTGGCTC CTGCATCAGC TACCCTGAAC AGTAAAACCA CAAGCATCGA GAACCTGCGG 
CTCCGGGCCA AGCAGCACGC GGCCTCCCTG GGACTCGATA CGCTGCCCAA CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011538970.1
CDS	262..1395
Translation	MQHYGVNGYSLHAMNSLSAMYNLHQQAAQQAQHAPDYRPSVHALTLAERLADIILEARYGSQHRKQRRSRTAFTAQQLEALEKTFQKTHYPDVVMRERLAMCTNLPEARVQVWFKNRRAKFRKKQRSLQKEQLQKQKEAEGSHGEGKAEAPTPDTQLDTEQPPRLPGSDPPAELHLSLSEQSASESAPEDQPDREEDPRAGAEDPKAEKSPGADSKGLGCKRGSPKADSPGSLTITPVAPGGGLLGPSHSYSSSPLSLFRLQEQFRQHMAATNNLVHYSSFEVGGPAPAAAAAAAAVPYLGVNMAPLGSLHCQSYYQSLSAAAAAHQGVWGSPLLPAPPAGLAPASATLNSKTTSIENLRLRAKQHAASLGLDTLPN

Target ORF information:

RefSeq Version	XM_011540668.2
Organism	Homo sapiens(human)
Definition	Homo sapiens diencephalon/mesencephalon homeobox 1 (DMBX1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011540668.2

ORF Insert Sequence:

ATGCAGCACT ACGGGGTGAA CGGCTACTCA CTGCACGCCA TGAACTCACT CAGCGCCATG 
TACAACCTGC ACCAGCAGGC AGCCCAGCAG GCCCAGCATG CCCCCGACTA CCGGCCTTCA 
GTGCATGCGC TTACATTGGC TGAGCGCCTG GCTGACATCA TCTTGGAGGC CCGTTATGGT 
TCCCAGCACC GCAAACAACG TCGCAGCCGC ACAGCGTTCA CGGCTCAGCA GCTCGAGGCC 
CTGGAAAAGA CCTTCCAGAA GACTCACTAC CCAGATGTGG TGATGCGTGA GAGGCTGGCC 
ATGTGCACCA ACCTGCCTGA GGCCCGGGTG CAGGTGTGGT TCAAGAACCG CCGGGCCAAG 
TTCCGGAAGA AGCAGCGTAG CCTGCAGAAG GAACAGCTCC AGAAGCAGAA GGAGGCTGAG 
GGCTCCCATG GGGAAGGCAA GGCCGAGGCC CCCACTCCAG ATACCCAGCT GGACACTGAG 
CAGCCCCCAC GTCTGCCTGG CAGCGACCCC CCTGCTGAGC TTCACCTGAG TCTGTCTGAG 
CAGTCAGCCA GTGAGTCAGC CCCCGAGGAT CAGCCGGACC GTGAGGAGGA CCCCAGGGCA 
GGGGCTGAGG ACCCCAAAGC TGAGAAGAGC CCTGGGGCTG ACAGCAAGGG GCTGGGCTGC 
AAGAGGGGCA GCCCCAAGGC AGATTCCCCA GGCAGCCTGA CCATCACTCC TGTGGCCCCA 
GGGGGTGGCC TCCTGGGCCC CTCCCACTCC TATTCCTCGT CCCCGCTGAG CCTCTTCCGT 
CTGCAGGAGC AATTCCGCCA GCACATGGCG GCCACCAACA ACCTGGTGCA CTACTCGTCC 
TTCGAAGTAG GGGGTCCGGC CCCTGCTGCT GCAGCGGCGG CTGCTGCTGT GCCCTACCTG 
GGCGTCAACA TGGCCCCGCT GGGCTCACTG CACTGCCAGT CCTACTACCA GTCCCTGTCA 
GCAGCCGCTG CTGCCCACCA GGGTGTGTGG GGGTCTCCTC TGCTGCCTGC ACCCCCAGCA 
GGCCTGGCTC CTGCATCAGC TACCCTGAAC AGTAAAACCA CAAGCATCGA GAACCTGCGG 
CTCCGGGCCA AGCAGCACGC GGCCTCCCTG GGACTCGATA CGCTGCCCAA CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

DMBX1 ( XM_017000289.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016855778.1 Homo sapiens diencephalon/mesencephalon homeobox 1 (DMBX1), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu10203
Clone ID Related Accession (Same CDS sequence)	XM_011540668.2 , XM_017000289.1 , NM_172225.2 , NM_172225.1
Accession Version	XM_017000289.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1134bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	diencephalon/mesencephalon homeobox protein 1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000001.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCAGCACT ACGGGGTGAA CGGCTACTCA CTGCACGCCA TGAACTCACT CAGCGCCATG 
TACAACCTGC ACCAGCAGGC AGCCCAGCAG GCCCAGCATG CCCCCGACTA CCGGCCTTCA 
GTGCATGCGC TTACATTGGC TGAGCGCCTG GCTGACATCA TCTTGGAGGC CCGTTATGGT 
TCCCAGCACC GCAAACAACG TCGCAGCCGC ACAGCGTTCA CGGCTCAGCA GCTCGAGGCC 
CTGGAAAAGA CCTTCCAGAA GACTCACTAC CCAGATGTGG TGATGCGTGA GAGGCTGGCC 
ATGTGCACCA ACCTGCCTGA GGCCCGGGTG CAGGTGTGGT TCAAGAACCG CCGGGCCAAG 
TTCCGGAAGA AGCAGCGTAG CCTGCAGAAG GAACAGCTCC AGAAGCAGAA GGAGGCTGAG 
GGCTCCCATG GGGAAGGCAA GGCCGAGGCC CCCACTCCAG ATACCCAGCT GGACACTGAG 
CAGCCCCCAC GTCTGCCTGG CAGCGACCCC CCTGCTGAGC TTCACCTGAG TCTGTCTGAG 
CAGTCAGCCA GTGAGTCAGC CCCCGAGGAT CAGCCGGACC GTGAGGAGGA CCCCAGGGCA 
GGGGCTGAGG ACCCCAAAGC TGAGAAGAGC CCTGGGGCTG ACAGCAAGGG GCTGGGCTGC 
AAGAGGGGCA GCCCCAAGGC AGATTCCCCA GGCAGCCTGA CCATCACTCC TGTGGCCCCA 
GGGGGTGGCC TCCTGGGCCC CTCCCACTCC TATTCCTCGT CCCCGCTGAG CCTCTTCCGT 
CTGCAGGAGC AATTCCGCCA GCACATGGCG GCCACCAACA ACCTGGTGCA CTACTCGTCC 
TTCGAAGTAG GGGGTCCGGC CCCTGCTGCT GCAGCGGCGG CTGCTGCTGT GCCCTACCTG 
GGCGTCAACA TGGCCCCGCT GGGCTCACTG CACTGCCAGT CCTACTACCA GTCCCTGTCA 
GCAGCCGCTG CTGCCCACCA GGGTGTGTGG GGGTCTCCTC TGCTGCCTGC ACCCCCAGCA 
GGCCTGGCTC CTGCATCAGC TACCCTGAAC AGTAAAACCA CAAGCATCGA GAACCTGCGG 
CTCCGGGCCA AGCAGCACGC GGCCTCCCTG GGACTCGATA CGCTGCCCAA CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016855778.1
CDS	54..1187
Translation	MQHYGVNGYSLHAMNSLSAMYNLHQQAAQQAQHAPDYRPSVHALTLAERLADIILEARYGSQHRKQRRSRTAFTAQQLEALEKTFQKTHYPDVVMRERLAMCTNLPEARVQVWFKNRRAKFRKKQRSLQKEQLQKQKEAEGSHGEGKAEAPTPDTQLDTEQPPRLPGSDPPAELHLSLSEQSASESAPEDQPDREEDPRAGAEDPKAEKSPGADSKGLGCKRGSPKADSPGSLTITPVAPGGGLLGPSHSYSSSPLSLFRLQEQFRQHMAATNNLVHYSSFEVGGPAPAAAAAAAAVPYLGVNMAPLGSLHCQSYYQSLSAAAAAHQGVWGSPLLPAPPAGLAPASATLNSKTTSIENLRLRAKQHAASLGLDTLPN

Target ORF information:

RefSeq Version	XM_017000289.1
Organism	Homo sapiens(human)
Definition	Homo sapiens diencephalon/mesencephalon homeobox 1 (DMBX1), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017000289.1

ORF Insert Sequence:

ATGCAGCACT ACGGGGTGAA CGGCTACTCA CTGCACGCCA TGAACTCACT CAGCGCCATG 
TACAACCTGC ACCAGCAGGC AGCCCAGCAG GCCCAGCATG CCCCCGACTA CCGGCCTTCA 
GTGCATGCGC TTACATTGGC TGAGCGCCTG GCTGACATCA TCTTGGAGGC CCGTTATGGT 
TCCCAGCACC GCAAACAACG TCGCAGCCGC ACAGCGTTCA CGGCTCAGCA GCTCGAGGCC 
CTGGAAAAGA CCTTCCAGAA GACTCACTAC CCAGATGTGG TGATGCGTGA GAGGCTGGCC 
ATGTGCACCA ACCTGCCTGA GGCCCGGGTG CAGGTGTGGT TCAAGAACCG CCGGGCCAAG 
TTCCGGAAGA AGCAGCGTAG CCTGCAGAAG GAACAGCTCC AGAAGCAGAA GGAGGCTGAG 
GGCTCCCATG GGGAAGGCAA GGCCGAGGCC CCCACTCCAG ATACCCAGCT GGACACTGAG 
CAGCCCCCAC GTCTGCCTGG CAGCGACCCC CCTGCTGAGC TTCACCTGAG TCTGTCTGAG 
CAGTCAGCCA GTGAGTCAGC CCCCGAGGAT CAGCCGGACC GTGAGGAGGA CCCCAGGGCA 
GGGGCTGAGG ACCCCAAAGC TGAGAAGAGC CCTGGGGCTG ACAGCAAGGG GCTGGGCTGC 
AAGAGGGGCA GCCCCAAGGC AGATTCCCCA GGCAGCCTGA CCATCACTCC TGTGGCCCCA 
GGGGGTGGCC TCCTGGGCCC CTCCCACTCC TATTCCTCGT CCCCGCTGAG CCTCTTCCGT 
CTGCAGGAGC AATTCCGCCA GCACATGGCG GCCACCAACA ACCTGGTGCA CTACTCGTCC 
TTCGAAGTAG GGGGTCCGGC CCCTGCTGCT GCAGCGGCGG CTGCTGCTGT GCCCTACCTG 
GGCGTCAACA TGGCCCCGCT GGGCTCACTG CACTGCCAGT CCTACTACCA GTCCCTGTCA 
GCAGCCGCTG CTGCCCACCA GGGTGTGTGG GGGTCTCCTC TGCTGCCTGC ACCCCCAGCA 
GGCCTGGCTC CTGCATCAGC TACCCTGAAC AGTAAAACCA CAAGCATCGA GAACCTGCGG 
CTCCGGGCCA AGCAGCACGC GGCCTCCCTG GGACTCGATA CGCTGCCCAA CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

DMBX1 ( NM_147192.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_671725.1 Homo sapiens diencephalon/mesencephalon homeobox 1 (DMBX1), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu10423
Clone ID Related Accession (Same CDS sequence)	NM_147192.2 , NM_147192.3
Accession Version	NM_147192.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1149bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-06-22
Organism	Homo sapiens(human)
Product	diencephalon/mesencephalon homeobox protein 1 isoform b
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL137797.9. On Dec 31, 2002 this sequence version replaced NM_147192.1. Transcript Variant: This variant (2) uses an alternate in-frame splice site, compared to variant 1. The encoded isoform (b) is longer than isoform a. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: AF398528.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2148874 [ECO:0000348] ##Evidence-Data-END##

ATGCAGCACT ACGGGGTGAA CGGCTACTCA CTGCACGCCA TGAACTCACT CAGCGCCATG 
TACAACCTGC ACCAGCAGGC AGCCCAGCAG GCCCAGCATG CCCCCGACTA CCGGCCTTCA 
GTGCATGCGC TTACATTGGC TGAGCGCCTG GCTGGCTGTA CATTTCAAGA CATCATCTTG 
GAGGCCCGTT ATGGTTCCCA GCACCGCAAA CAACGTCGCA GCCGCACAGC GTTCACGGCT 
CAGCAGCTCG AGGCCCTGGA AAAGACCTTC CAGAAGACTC ACTACCCAGA TGTGGTGATG 
CGTGAGAGGC TGGCCATGTG CACCAACCTG CCTGAGGCCC GGGTGCAGGT GTGGTTCAAG 
AACCGCCGGG CCAAGTTCCG GAAGAAGCAG CGTAGCCTGC AGAAGGAACA GCTCCAGAAG 
CAGAAGGAGG CTGAGGGCTC CCATGGGGAA GGCAAGGCCG AGGCCCCCAC TCCAGATACC 
CAGCTGGACA CTGAGCAGCC CCCACGTCTG CCTGGCAGCG ACCCCCCTGC TGAGCTTCAC 
CTGAGTCTGT CTGAGCAGTC AGCCAGTGAG TCAGCCCCCG AGGATCAGCC GGACCGTGAG 
GAGGACCCCA GGGCAGGGGC TGAGGACCCC AAAGCTGAGA AGAGCCCTGG GGCTGACAGC 
AAGGGGCTGG GCTGCAAGAG GGGCAGCCCC AAGGCAGATT CCCCAGGCAG CCTGACCATC 
ACTCCTGTGG CCCCAGGGGG TGGCCTCCTG GGCCCCTCCC ACTCCTATTC CTCGTCCCCG 
CTGAGCCTCT TCCGTCTGCA GGAGCAATTC CGCCAGCACA TGGCGGCCAC CAACAACCTG 
GTGCACTACT CGTCCTTCGA AGTAGGGGGT CCGGCCCCTG CTGCTGCAGC GGCGGCTGCT 
GCTGTGCCCT ACCTGGGCGT CAACATGGCC CCGCTGGGCT CACTGCACTG CCAGTCCTAC 
TACCAGTCCC TGTCAGCAGC CGCTGCTGCC CACCAGGGTG TGTGGGGGTC TCCTCTGCTG 
CCTGCACCCC CAGCAGGCCT GGCTCCTGCA TCAGCTACCC TGAACAGTAA AACCACAAGC 
ATCGAGAACC TGCGGCTCCG GGCCAAGCAG CACGCGGCCT CCCTGGGACT CGATACGCTG 
CCCAACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_671725.1
CDS	16..1164
Translation	MQHYGVNGYSLHAMNSLSAMYNLHQQAAQQAQHAPDYRPSVHALTLAERLAGCTFQDIILEARYGSQHRKQRRSRTAFTAQQLEALEKTFQKTHYPDVVMRERLAMCTNLPEARVQVWFKNRRAKFRKKQRSLQKEQLQKQKEAEGSHGEGKAEAPTPDTQLDTEQPPRLPGSDPPAELHLSLSEQSASESAPEDQPDREEDPRAGAEDPKAEKSPGADSKGLGCKRGSPKADSPGSLTITPVAPGGGLLGPSHSYSSSPLSLFRLQEQFRQHMAATNNLVHYSSFEVGGPAPAAAAAAAAVPYLGVNMAPLGSLHCQSYYQSLSAAAAAHQGVWGSPLLPAPPAGLAPASATLNSKTTSIENLRLRAKQHAASLGLDTLPN

Target ORF information:

RefSeq Version	NM_147192.2
Organism	Homo sapiens(human)
Definition	Homo sapiens diencephalon/mesencephalon homeobox 1 (DMBX1), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_147192.2

ORF Insert Sequence:

ATGCAGCACT ACGGGGTGAA CGGCTACTCA CTGCACGCCA TGAACTCACT CAGCGCCATG 
TACAACCTGC ACCAGCAGGC AGCCCAGCAG GCCCAGCATG CCCCCGACTA CCGGCCTTCA 
GTGCATGCGC TTACATTGGC TGAGCGCCTG GCTGGCTGTA CATTTCAAGA CATCATCTTG 
GAGGCCCGTT ATGGTTCCCA GCACCGCAAA CAACGTCGCA GCCGCACAGC GTTCACGGCT 
CAGCAGCTCG AGGCCCTGGA AAAGACCTTC CAGAAGACTC ACTACCCAGA TGTGGTGATG 
CGTGAGAGGC TGGCCATGTG CACCAACCTG CCTGAGGCCC GGGTGCAGGT GTGGTTCAAG 
AACCGCCGGG CCAAGTTCCG GAAGAAGCAG CGTAGCCTGC AGAAGGAACA GCTCCAGAAG 
CAGAAGGAGG CTGAGGGCTC CCATGGGGAA GGCAAGGCCG AGGCCCCCAC TCCAGATACC 
CAGCTGGACA CTGAGCAGCC CCCACGTCTG CCTGGCAGCG ACCCCCCTGC TGAGCTTCAC 
CTGAGTCTGT CTGAGCAGTC AGCCAGTGAG TCAGCCCCCG AGGATCAGCC GGACCGTGAG 
GAGGACCCCA GGGCAGGGGC TGAGGACCCC AAAGCTGAGA AGAGCCCTGG GGCTGACAGC 
AAGGGGCTGG GCTGCAAGAG GGGCAGCCCC AAGGCAGATT CCCCAGGCAG CCTGACCATC 
ACTCCTGTGG CCCCAGGGGG TGGCCTCCTG GGCCCCTCCC ACTCCTATTC CTCGTCCCCG 
CTGAGCCTCT TCCGTCTGCA GGAGCAATTC CGCCAGCACA TGGCGGCCAC CAACAACCTG 
GTGCACTACT CGTCCTTCGA AGTAGGGGGT CCGGCCCCTG CTGCTGCAGC GGCGGCTGCT 
GCTGTGCCCT ACCTGGGCGT CAACATGGCC CCGCTGGGCT CACTGCACTG CCAGTCCTAC 
TACCAGTCCC TGTCAGCAGC CGCTGCTGCC CACCAGGGTG TGTGGGGGTC TCCTCTGCTG 
CCTGCACCCC CAGCAGGCCT GGCTCCTGCA TCAGCTACCC TGAACAGTAA AACCACAAGC 
ATCGAGAACC TGCGGCTCCG GGCCAAGCAG CACGCGGCCT CCCTGGGACT CGATACGCTG 
CCCAACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

DMBX1 ( NM_147192.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_671725.1 Homo sapiens diencephalon/mesencephalon homeobox 1 (DMBX1), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu10423
Clone ID Related Accession (Same CDS sequence)	NM_147192.2 , NM_147192.3
Accession Version	NM_147192.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1149bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-06
Organism	Homo sapiens(human)
Product	diencephalon/mesencephalon homeobox protein 1 isoform b
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL137797.9. On May 9, 2019 this sequence version replaced NM_147192.2. Transcript Variant: This variant (2) uses an alternate in-frame splice site, compared to variant 1. The encoded isoform (b) is longer than isoform a. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: AF398528.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2148874 [ECO:0000348] ##Evidence-Data-END##

ATGCAGCACT ACGGGGTGAA CGGCTACTCA CTGCACGCCA TGAACTCACT CAGCGCCATG 
TACAACCTGC ACCAGCAGGC AGCCCAGCAG GCCCAGCATG CCCCCGACTA CCGGCCTTCA 
GTGCATGCGC TTACATTGGC TGAGCGCCTG GCTGGCTGTA CATTTCAAGA CATCATCTTG 
GAGGCCCGTT ATGGTTCCCA GCACCGCAAA CAACGTCGCA GCCGCACAGC GTTCACGGCT 
CAGCAGCTCG AGGCCCTGGA AAAGACCTTC CAGAAGACTC ACTACCCAGA TGTGGTGATG 
CGTGAGAGGC TGGCCATGTG CACCAACCTG CCTGAGGCCC GGGTGCAGGT GTGGTTCAAG 
AACCGCCGGG CCAAGTTCCG GAAGAAGCAG CGTAGCCTGC AGAAGGAACA GCTCCAGAAG 
CAGAAGGAGG CTGAGGGCTC CCATGGGGAA GGCAAGGCCG AGGCCCCCAC TCCAGATACC 
CAGCTGGACA CTGAGCAGCC CCCACGTCTG CCTGGCAGCG ACCCCCCTGC TGAGCTTCAC 
CTGAGTCTGT CTGAGCAGTC AGCCAGTGAG TCAGCCCCCG AGGATCAGCC GGACCGTGAG 
GAGGACCCCA GGGCAGGGGC TGAGGACCCC AAAGCTGAGA AGAGCCCTGG GGCTGACAGC 
AAGGGGCTGG GCTGCAAGAG GGGCAGCCCC AAGGCAGATT CCCCAGGCAG CCTGACCATC 
ACTCCTGTGG CCCCAGGGGG TGGCCTCCTG GGCCCCTCCC ACTCCTATTC CTCGTCCCCG 
CTGAGCCTCT TCCGTCTGCA GGAGCAATTC CGCCAGCACA TGGCGGCCAC CAACAACCTG 
GTGCACTACT CGTCCTTCGA AGTAGGGGGT CCGGCCCCTG CTGCTGCAGC GGCGGCTGCT 
GCTGTGCCCT ACCTGGGCGT CAACATGGCC CCGCTGGGCT CACTGCACTG CCAGTCCTAC 
TACCAGTCCC TGTCAGCAGC CGCTGCTGCC CACCAGGGTG TGTGGGGGTC TCCTCTGCTG 
CCTGCACCCC CAGCAGGCCT GGCTCCTGCA TCAGCTACCC TGAACAGTAA AACCACAAGC 
ATCGAGAACC TGCGGCTCCG GGCCAAGCAG CACGCGGCCT CCCTGGGACT CGATACGCTG 
CCCAACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_671725.1
CDS	13..1161
Translation	MQHYGVNGYSLHAMNSLSAMYNLHQQAAQQAQHAPDYRPSVHALTLAERLAGCTFQDIILEARYGSQHRKQRRSRTAFTAQQLEALEKTFQKTHYPDVVMRERLAMCTNLPEARVQVWFKNRRAKFRKKQRSLQKEQLQKQKEAEGSHGEGKAEAPTPDTQLDTEQPPRLPGSDPPAELHLSLSEQSASESAPEDQPDREEDPRAGAEDPKAEKSPGADSKGLGCKRGSPKADSPGSLTITPVAPGGGLLGPSHSYSSSPLSLFRLQEQFRQHMAATNNLVHYSSFEVGGPAPAAAAAAAAVPYLGVNMAPLGSLHCQSYYQSLSAAAAAHQGVWGSPLLPAPPAGLAPASATLNSKTTSIENLRLRAKQHAASLGLDTLPN

Target ORF information:

RefSeq Version	NM_147192.3
Organism	Homo sapiens(human)
Definition	Homo sapiens diencephalon/mesencephalon homeobox 1 (DMBX1), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_147192.3

ORF Insert Sequence:

ATGCAGCACT ACGGGGTGAA CGGCTACTCA CTGCACGCCA TGAACTCACT CAGCGCCATG 
TACAACCTGC ACCAGCAGGC AGCCCAGCAG GCCCAGCATG CCCCCGACTA CCGGCCTTCA 
GTGCATGCGC TTACATTGGC TGAGCGCCTG GCTGGCTGTA CATTTCAAGA CATCATCTTG 
GAGGCCCGTT ATGGTTCCCA GCACCGCAAA CAACGTCGCA GCCGCACAGC GTTCACGGCT 
CAGCAGCTCG AGGCCCTGGA AAAGACCTTC CAGAAGACTC ACTACCCAGA TGTGGTGATG 
CGTGAGAGGC TGGCCATGTG CACCAACCTG CCTGAGGCCC GGGTGCAGGT GTGGTTCAAG 
AACCGCCGGG CCAAGTTCCG GAAGAAGCAG CGTAGCCTGC AGAAGGAACA GCTCCAGAAG 
CAGAAGGAGG CTGAGGGCTC CCATGGGGAA GGCAAGGCCG AGGCCCCCAC TCCAGATACC 
CAGCTGGACA CTGAGCAGCC CCCACGTCTG CCTGGCAGCG ACCCCCCTGC TGAGCTTCAC 
CTGAGTCTGT CTGAGCAGTC AGCCAGTGAG TCAGCCCCCG AGGATCAGCC GGACCGTGAG 
GAGGACCCCA GGGCAGGGGC TGAGGACCCC AAAGCTGAGA AGAGCCCTGG GGCTGACAGC 
AAGGGGCTGG GCTGCAAGAG GGGCAGCCCC AAGGCAGATT CCCCAGGCAG CCTGACCATC 
ACTCCTGTGG CCCCAGGGGG TGGCCTCCTG GGCCCCTCCC ACTCCTATTC CTCGTCCCCG 
CTGAGCCTCT TCCGTCTGCA GGAGCAATTC CGCCAGCACA TGGCGGCCAC CAACAACCTG 
GTGCACTACT CGTCCTTCGA AGTAGGGGGT CCGGCCCCTG CTGCTGCAGC GGCGGCTGCT 
GCTGTGCCCT ACCTGGGCGT CAACATGGCC CCGCTGGGCT CACTGCACTG CCAGTCCTAC 
TACCAGTCCC TGTCAGCAGC CGCTGCTGCC CACCAGGGTG TGTGGGGGTC TCCTCTGCTG 
CCTGCACCCC CAGCAGGCCT GGCTCCTGCA TCAGCTACCC TGAACAGTAA AACCACAAGC 
ATCGAGAACC TGCGGCTCCG GGCCAAGCAG CACGCGGCCT CCCTGGGACT CGATACGCTG 
CCCAACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Epigenome-wide association data implicates DNA methylation-mediated genetic risk in psoriasis.
Clinical epigenetics8131(2016)
Zhou F,Shen C,Xu J,Gao J,Zheng X,Ko R,Dou J,Cheng Y,Zhu C,Xu S,Tang X,Zuo X,Yin X,Cui Y,Sun L,Tsoi LC,Hsu YH,Yang S,Zhang X

An atlas of genetic influences on human blood metabolites.
Nature genetics46(6)543-550(2014 Jun)
Shin SY,Fauman EB,Petersen AK,Krumsiek J,Santos R,Huang J,Arnold M,Erte I,Forgetta V,Yang TP,Walter K,Menni C,Chen L,Vasquez L,Valdes AM,Hyde CL,Wang V,Ziemek D,Roberts P,Xi L,Grundberg E,,Waldenberger M,Richards JB,Mohney RP,Milburn MV,John SL,Trimmer J,Theis FJ,Overington JP,Suhre K,Brosnan MJ,Gieger C,Kastenm?ller G,Spector TD,Soranzo N

A census of human transcription factors: function, expression and evolution.
Nature reviews. Genetics10(4)252-63(2009 04)
Vaquerizas JM,Kummerfeld SK,Teichmann SA,Luscombe NM

Mutational analysis of the human MBX gene in four Korean families demonstrating microphthalmia with congenital cataract.
The Turkish journal of pediatrics49(3)334-6(2007 Jul-Sep)
Miyamoto T,Yu YS,Sato H,Hayashi H,Sakugawa N,Ishikawa M,Sengoku K

The homeobox gene mbx is involved in eye and tectum development.
Developmental biology248(1)107-17(2002 Aug)
Kawahara A,Chien CB,Dawid IB

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DMBX1 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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