SLC27A2 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	SLC27A2
Entrez Gene ID	11001
Full Name	solute carrier family 27 member 2
Synonyms	ACSVL1,FACVL1,FATP2,HsT17226,VLACS,VLCS,hFACVL1
General protein information	Preferred Names solute carrier family 27 member 2 Names very long-chain acyl-CoA synthetase FATP-2 THCA-CoA ligase fatty acid transport protein 2 fatty-acid-coenzyme A ligase, very long-chain 1 long-chain-fatty-acid--CoA ligase solute carrier family 27 (fatty acid transporter), member 2 very long-chain fatty-acid-coenzyme A ligase 1 very long-chain-fatty-acid-CoA ligase
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 15 Map Location: 15q21.2
Summary	The protein encoded by this gene is an isozyme of long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. This isozyme activates long-chain, branched-chain and very-long-chain fatty acids containing 22 or more carbons to their CoA derivatives. It is expressed primarily in liver and kidney, and is present in both endoplasmic reticulum and peroxisomes, but not in mitochondria. Its decreased peroxisomal enzyme activity is in part responsible for the biochemical pathology in X-linked adrenoleukodystrophy. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2009].
Disorder MIM:	603247

mRNA and Protein(s)

mRNA	Protein	Name
NM_003645.3	NP_003636.2	very long-chain acyl-CoA synthetase isoform 1
NM_001159629.1	NP_001153101.1	very long-chain acyl-CoA synthetase isoform 2
NM_003645.4	NP_003636.2	very long-chain acyl-CoA synthetase isoform 1

Pathways from BioSystems

Homologies

Homo sapiens (human)	SLC27A2	NP_003636.2
	SLC27A2	XP_001114121.1
Canis lupus familiaris (dog)	SLC27A2	XP_535473.2
Rattus norvegicus (Norway rat)	Slc27a2	NP_113924.1
Magnaporthe oryzae (rice blast fungus)	MGG_05025	XP_003712531.1
Bos taurus (cattle)	SLC27A2	NP_001179792.1
Danio rerio (zebrafish)	slc27a2b	XP_001336957.1
Xenopus tropicalis (tropical clawed frog)	LOC100494612	XP_002938916.1
Pan troglodytes (chimpanzee)	SLC27A2	XP_510394.2
Mus musculus (house mouse)	Slc27a2	NP_036108.2
Gallus gallus (chicken)	SLC27A2	XP_424010.3
Danio rerio (zebrafish)	zgc:101540	NP_001008639.1

Gene Ontology
Bibliography

Related articles in PubMed

Protein expression of fatty acid transporter 2 is polarized to the trophoblast basal plasma membrane and increased in placentas from overweight/obese women.
Lager S, Ramirez VI, Gaccioli F, Jang B, Jansson T, Powell TL
Placenta4060-6(2016 Apr)

Fatty acid transport protein-2 inhibitor Grassofermata/CB5 protects cells against lipid accumulation and toxicity.
Saini N, Black PN, Montefusco D, DiRusso CC
Biochemical and biophysical research communications465(3)534-41(2015 Sep)

Influence of breastfeeding on blood-cell transcript-based biomarkers of health in children.
Priego T, S?nchez J, Pic? C, Ahrens W, Bammann K, De Henauw S, Fraterman A, Iacoviello L, Lissner L, Moln?r D, Moreno LA, Siani A, Tornaritis M, Veidebaum T, Palou A,
Pediatric obesity9(6)463-70(2014 Dec)

An atlas of genetic influences on human blood metabolites.
Shin SY, Fauman EB, Petersen AK, Krumsiek J, Santos R, Huang J, Arnold M, Erte I, Forgetta V, Yang TP, Walter K, Menni C, Chen L, Vasquez L, Valdes AM, Hyde CL, Wang V, Ziemek D, Roberts P, Xi L, Grundberg E, , Waldenberger M, Richards JB, Mohney RP, Milburn MV, John SL, Trimmer J, Theis FJ, Overington JP, Suhre K, Brosnan MJ, Gieger C, Kastenm?ller G, Spector TD, Soranzo N
Nature genetics46(6)543-550(2014 Jun)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

In overweight/obese pregnancies, the increased FATP2 placental expression could contribute to increased fatty acid delivery to the fetus.
Title: Protein expression of fatty acid transporter 2 is polarized to the trophoblast basal plasma membrane and increased in placentas from overweight/obese women.

In mice Grassofermata decreased absorption of (13)C-oleate demonstrating its potential as a therapeutic agent.
Title: Fatty acid transport protein-2 inhibitor Grassofermata/CB5 protects cells against lipid accumulation and toxicity.

Protective effects of breastfeeding are reflected in higher expression levels of SLC27A2, FASN, PPARalpha and INSR in blood cells.
Title: Influence of breastfeeding on blood-cell transcript-based biomarkers of health in children.

these data support the conclusion that FATP2 has a dual function in the pathways linking the transport and activation of exogenous fatty acids.
Title: Overexpression of human fatty acid transport protein 2/very long chain acyl-CoA synthetase 1 (FATP2/Acsvl1) reveals distinct patterns of trafficking of exogenous fatty acids.

even though hypoxia regulates the expression of FATP2 and FATP4 in human trophoblasts, mouse Fatp2 and Fatp4 are not essential for intrauterine fetal growth.
Title: The expression and function of fatty acid transport protein-2 and -4 in the murine placenta.

The following SLC27A2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the SLC27A2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu09077	NM_003645.4 Latest version!	Homo sapiens solute carrier family 27 member 2 (SLC27A2), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$259.50-$363.30 $519.00
OHu09179	NM_001159629.1 Latest version!	Homo sapiens solute carrier family 27 member 2 (SLC27A2), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$265.30 $379.00
View Old Accession Versions >>
OHu09077	NM_003645.3	Homo sapiens solute carrier family 27 member 2 (SLC27A2), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$259.50-$363.30 $519.00
Hide Old Accession Versions >>

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***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

SLC27A2 ( NM_003645.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_003636.2 Homo sapiens solute carrier family 27 member 2 (SLC27A2), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu09077
Clone ID Related Accession (Same CDS sequence)	NM_003645.3 , NM_003645.4
Accession Version	NM_003645.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1863bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Homo sapiens(human)
Product	very long-chain acyl-CoA synthetase isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK290262.1, AK223145.1 and BM980042.1. On Apr 25, 2009 this sequence version replaced NM_003645.2. Transcript Variant: This variant (1) represents the predominant transcript and encodes the longer isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK290262.1, SRR1660807.53854.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCTTTCCG CCATCTACAC AGTCCTGGCG GGACTGCTGT TCCTGCCGCT CCTGGTGAAC 
CTCTGCTGCC CATACTTCTT CCAGGACATA GGCTACTTCT TGAAGGTGGC CGCCGTGGGC 
CGGAGGGTGC GCAGCTACGG GAAGCGGCGG CCGGCGCGCA CCATCCTGCG GGCGTTCCTG 
GAGAAAGCGC GCCAGACGCC ACACAAGCCT TTTCTGCTCT TCCGCGACGA GACTCTCACC 
TACGCGCAGG TGGACCGGCG CAGCAATCAA GTGGCCCGGG CGCTGCACGA CCACCTCGGC 
CTGCGCCAGG GAGACTGCGT GGCGCTCCTT ATGGGTAACG AGCCGGCCTA CGTGTGGCTG 
TGGCTGGGGC TGGTGAAGCT GGGCTGTGCC ATGGCGTGCC TCAATTACAA CATCCGCGCG 
AAGTCCCTGC TGCACTGCTT CCAGTGCTGC GGGGCGAAGG TGCTGCTGGT GTCGCCAGAA 
CTACAAGCAG CTGTCGAAGA GATACTGCCA AGCCTTAAAA AAGATGATGT GTCCATCTAT 
TATGTGAGCA GAACTTCTAA CACAGATGGG ATTGACTCTT TCCTGGACAA AGTGGATGAA 
GTATCAACTG AACCTATCCC AGAGTCATGG AGGTCTGAAG TCACTTTTTC CACTCCTGCC 
TTATACATTT ATACTTCTGG AACCACAGGT CTTCCAAAAG CAGCCATGAT CACTCATCAG 
CGCATATGGT ATGGAACTGG CCTCACTTTT GTAAGCGGAT TGAAGGCAGA TGATGTCATC 
TATATCACTC TGCCCTTTTA CCACAGTGCT GCACTACTGA TTGGCATTCA CGGATGTATT 
GTGGCTGGTG CTACTCTTGC CTTGCGGACT AAATTTTCAG CCAGCCAGTT TTGGGATGAC 
TGCAGAAAAT ACAACGTCAC TGTCATTCAG TATATCGGTG AACTGCTTCG GTATTTATGC 
AACTCACCAC AGAAACCAAA TGACCGTGAT CATAAAGTGA GACTGGCACT GGGAAATGGC 
TTACGAGGAG ATGTGTGGAG ACAATTTGTC AAGAGATTTG GGGACATATG CATCTATGAG 
TTCTATGCTG CCACTGAAGG CAATATTGGA TTTATGAATT ATGCGAGAAA AGTTGGTGCT 
GTTGGAAGAG TAAACTACCT ACAGAAAAAA ATCATAACTT ATGACCTGAT TAAATATGAT 
GTGGAGAAAG ATGAACCTGT CCGTGATGAA AATGGATATT GCGTCAGAGT TCCCAAAGGT 
GAAGTTGGAC TTCTGGTTTG CAAAATCACA CAACTTACAC CATTTAATGG CTATGCTGGA 
GCAAAGGCTC AGACAGAGAA GAAAAAACTG AGAGATGTCT TTAAGAAAGG AGACCTCTAT 
TTCAACAGTG GAGATCTCTT AATGGTTGAC CATGAAAATT TCATCTATTT CCACGACAGA 
GTTGGAGATA CATTCCGGTG GAAAGGGGAA AATGTGGCCA CCACTGAAGT TGCTGATACA 
GTTGGACTGG TTGATTTTGT CCAAGAAGTA AATGTTTATG GAGTGCATGT GCCAGATCAT 
GAGGGTCGCA TTGGCATGGC CTCCATCAAA ATGAAAGAAA ACCATGAATT TGATGGAAAG 
AAACTCTTTC AGCACATTGC TGATTACCTA CCTAGTTATG CAAGGCCCCG GTTTCTAAGA 
ATACAGGACA CCATTGAGAT CACTGGAACT TTTAAACACC GCAAAATGAC CCTGGTGGAG 
GAGGGCTTTA ACCCTGCTGT CATCAAAGAT GCCTTGTATT TCTTGGATGA CACAGCAAAA 
ATGTATGTGC CTATGACTGA GGACATCTAT AATGCCATAA GTGCTAAAAC CCTGAAACTC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_003636.2
CDS	233..2095
Translation	MLSAIYTVLAGLLFLPLLVNLCCPYFFQDIGYFLKVAAVGRRVRSYGKRRPARTILRAFLEKARQTPHKPFLLFRDETLTYAQVDRRSNQVARALHDHLGLRQGDCVALLMGNEPAYVWLWLGLVKLGCAMACLNYNIRAKSLLHCFQCCGAKVLLVSPELQAAVEEILPSLKKDDVSIYYVSRTSNTDGIDSFLDKVDEVSTEPIPESWRSEVTFSTPALYIYTSGTTGLPKAAMITHQRIWYGTGLTFVSGLKADDVIYITLPFYHSAALLIGIHGCIVAGATLALRTKFSASQFWDDCRKYNVTVIQYIGELLRYLCNSPQKPNDRDHKVRLALGNGLRGDVWRQFVKRFGDICIYEFYAATEGNIGFMNYARKVGAVGRVNYLQKKIITYDLIKYDVEKDEPVRDENGYCVRVPKGEVGLLVCKITQLTPFNGYAGAKAQTEKKKLRDVFKKGDLYFNSGDLLMVDHENFIYFHDRVGDTFRWKGENVATTEVADTVGLVDFVQEVNVYGVHVPDHEGRIGMASIKMKENHEFDGKKLFQHIADYLPSYARPRFLRIQDTIEITGTFKHRKMTLVEEGFNPAVIKDALYFLDDTAKMYVPMTEDIYNAISAKTLKL

Target ORF information:

RefSeq Version	NM_003645.3
Organism	Homo sapiens(human)
Definition	Homo sapiens solute carrier family 27 member 2 (SLC27A2), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_003645.3

ORF Insert Sequence:

ATGCTTTCCG CCATCTACAC AGTCCTGGCG GGACTGCTGT TCCTGCCGCT CCTGGTGAAC 
CTCTGCTGCC CATACTTCTT CCAGGACATA GGCTACTTCT TGAAGGTGGC CGCCGTGGGC 
CGGAGGGTGC GCAGCTACGG GAAGCGGCGG CCGGCGCGCA CCATCCTGCG GGCGTTCCTG 
GAGAAAGCGC GCCAGACGCC ACACAAGCCT TTTCTGCTCT TCCGCGACGA GACTCTCACC 
TACGCGCAGG TGGACCGGCG CAGCAATCAA GTGGCCCGGG CGCTGCACGA CCACCTCGGC 
CTGCGCCAGG GAGACTGCGT GGCGCTCCTT ATGGGTAACG AGCCGGCCTA CGTGTGGCTG 
TGGCTGGGGC TGGTGAAGCT GGGCTGTGCC ATGGCGTGCC TCAATTACAA CATCCGCGCG 
AAGTCCCTGC TGCACTGCTT CCAGTGCTGC GGGGCGAAGG TGCTGCTGGT GTCGCCAGAA 
CTACAAGCAG CTGTCGAAGA GATACTGCCA AGCCTTAAAA AAGATGATGT GTCCATCTAT 
TATGTGAGCA GAACTTCTAA CACAGATGGG ATTGACTCTT TCCTGGACAA AGTGGATGAA 
GTATCAACTG AACCTATCCC AGAGTCATGG AGGTCTGAAG TCACTTTTTC CACTCCTGCC 
TTATACATTT ATACTTCTGG AACCACAGGT CTTCCAAAAG CAGCCATGAT CACTCATCAG 
CGCATATGGT ATGGAACTGG CCTCACTTTT GTAAGCGGAT TGAAGGCAGA TGATGTCATC 
TATATCACTC TGCCCTTTTA CCACAGTGCT GCACTACTGA TTGGCATTCA CGGATGTATT 
GTGGCTGGTG CTACTCTTGC CTTGCGGACT AAATTTTCAG CCAGCCAGTT TTGGGATGAC 
TGCAGAAAAT ACAACGTCAC TGTCATTCAG TATATCGGTG AACTGCTTCG GTATTTATGC 
AACTCACCAC AGAAACCAAA TGACCGTGAT CATAAAGTGA GACTGGCACT GGGAAATGGC 
TTACGAGGAG ATGTGTGGAG ACAATTTGTC AAGAGATTTG GGGACATATG CATCTATGAG 
TTCTATGCTG CCACTGAAGG CAATATTGGA TTTATGAATT ATGCGAGAAA AGTTGGTGCT 
GTTGGAAGAG TAAACTACCT ACAGAAAAAA ATCATAACTT ATGACCTGAT TAAATATGAT 
GTGGAGAAAG ATGAACCTGT CCGTGATGAA AATGGATATT GCGTCAGAGT TCCCAAAGGT 
GAAGTTGGAC TTCTGGTTTG CAAAATCACA CAACTTACAC CATTTAATGG CTATGCTGGA 
GCAAAGGCTC AGACAGAGAA GAAAAAACTG AGAGATGTCT TTAAGAAAGG AGACCTCTAT 
TTCAACAGTG GAGATCTCTT AATGGTTGAC CATGAAAATT TCATCTATTT CCACGACAGA 
GTTGGAGATA CATTCCGGTG GAAAGGGGAA AATGTGGCCA CCACTGAAGT TGCTGATACA 
GTTGGACTGG TTGATTTTGT CCAAGAAGTA AATGTTTATG GAGTGCATGT GCCAGATCAT 
GAGGGTCGCA TTGGCATGGC CTCCATCAAA ATGAAAGAAA ACCATGAATT TGATGGAAAG 
AAACTCTTTC AGCACATTGC TGATTACCTA CCTAGTTATG CAAGGCCCCG GTTTCTAAGA 
ATACAGGACA CCATTGAGAT CACTGGAACT TTTAAACACC GCAAAATGAC CCTGGTGGAG 
GAGGGCTTTA ACCCTGCTGT CATCAAAGAT GCCTTGTATT TCTTGGATGA CACAGCAAAA 
ATGTATGTGC CTATGACTGA GGACATCTAT AATGCCATAA GTGCTAAAAC CCTGAAACTC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SLC27A2 ( NM_003645.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_003636.2 Homo sapiens solute carrier family 27 member 2 (SLC27A2), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu09077
Clone ID Related Accession (Same CDS sequence)	NM_003645.3 , NM_003645.4
Accession Version	NM_003645.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1863bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-23
Organism	Homo sapiens(human)
Product	very long-chain acyl-CoA synthetase isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK290262.1 and AK223145.1. On Nov 22, 2018 this sequence version replaced NM_003645.3. Transcript Variant: This variant (1) represents the predominant transcript and encodes the longer isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK290262.1, SRR1660807.53854.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000267842.10/ ENSP00000267842.5 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGCTTTCCG CCATCTACAC AGTCCTGGCG GGACTGCTGT TCCTGCCGCT CCTGGTGAAC 
CTCTGCTGCC CATACTTCTT CCAGGACATA GGCTACTTCT TGAAGGTGGC CGCCGTGGGC 
CGGAGGGTGC GCAGCTACGG GAAGCGGCGG CCGGCGCGCA CCATCCTGCG GGCGTTCCTG 
GAGAAAGCGC GCCAGACGCC ACACAAGCCT TTTCTGCTCT TCCGCGACGA GACTCTCACC 
TACGCGCAGG TGGACCGGCG CAGCAATCAA GTGGCCCGGG CGCTGCACGA CCACCTCGGC 
CTGCGCCAGG GAGACTGCGT GGCGCTCCTT ATGGGTAACG AGCCGGCCTA CGTGTGGCTG 
TGGCTGGGGC TGGTGAAGCT GGGCTGTGCC ATGGCGTGCC TCAATTACAA CATCCGCGCG 
AAGTCCCTGC TGCACTGCTT CCAGTGCTGC GGGGCGAAGG TGCTGCTGGT GTCGCCAGAA 
CTACAAGCAG CTGTCGAAGA GATACTGCCA AGCCTTAAAA AAGATGATGT GTCCATCTAT 
TATGTGAGCA GAACTTCTAA CACAGATGGG ATTGACTCTT TCCTGGACAA AGTGGATGAA 
GTATCAACTG AACCTATCCC AGAGTCATGG AGGTCTGAAG TCACTTTTTC CACTCCTGCC 
TTATACATTT ATACTTCTGG AACCACAGGT CTTCCAAAAG CAGCCATGAT CACTCATCAG 
CGCATATGGT ATGGAACTGG CCTCACTTTT GTAAGCGGAT TGAAGGCAGA TGATGTCATC 
TATATCACTC TGCCCTTTTA CCACAGTGCT GCACTACTGA TTGGCATTCA CGGATGTATT 
GTGGCTGGTG CTACTCTTGC CTTGCGGACT AAATTTTCAG CCAGCCAGTT TTGGGATGAC 
TGCAGAAAAT ACAACGTCAC TGTCATTCAG TATATCGGTG AACTGCTTCG GTATTTATGC 
AACTCACCAC AGAAACCAAA TGACCGTGAT CATAAAGTGA GACTGGCACT GGGAAATGGC 
TTACGAGGAG ATGTGTGGAG ACAATTTGTC AAGAGATTTG GGGACATATG CATCTATGAG 
TTCTATGCTG CCACTGAAGG CAATATTGGA TTTATGAATT ATGCGAGAAA AGTTGGTGCT 
GTTGGAAGAG TAAACTACCT ACAGAAAAAA ATCATAACTT ATGACCTGAT TAAATATGAT 
GTGGAGAAAG ATGAACCTGT CCGTGATGAA AATGGATATT GCGTCAGAGT TCCCAAAGGT 
GAAGTTGGAC TTCTGGTTTG CAAAATCACA CAACTTACAC CATTTAATGG CTATGCTGGA 
GCAAAGGCTC AGACAGAGAA GAAAAAACTG AGAGATGTCT TTAAGAAAGG AGACCTCTAT 
TTCAACAGTG GAGATCTCTT AATGGTTGAC CATGAAAATT TCATCTATTT CCACGACAGA 
GTTGGAGATA CATTCCGGTG GAAAGGGGAA AATGTGGCCA CCACTGAAGT TGCTGATACA 
GTTGGACTGG TTGATTTTGT CCAAGAAGTA AATGTTTATG GAGTGCATGT GCCAGATCAT 
GAGGGTCGCA TTGGCATGGC CTCCATCAAA ATGAAAGAAA ACCATGAATT TGATGGAAAG 
AAACTCTTTC AGCACATTGC TGATTACCTA CCTAGTTATG CAAGGCCCCG GTTTCTAAGA 
ATACAGGACA CCATTGAGAT CACTGGAACT TTTAAACACC GCAAAATGAC CCTGGTGGAG 
GAGGGCTTTA ACCCTGCTGT CATCAAAGAT GCCTTGTATT TCTTGGATGA CACAGCAAAA 
ATGTATGTGC CTATGACTGA GGACATCTAT AATGCCATAA GTGCTAAAAC CCTGAAACTC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_003636.2
CDS	233..2095
Translation	MLSAIYTVLAGLLFLPLLVNLCCPYFFQDIGYFLKVAAVGRRVRSYGKRRPARTILRAFLEKARQTPHKPFLLFRDETLTYAQVDRRSNQVARALHDHLGLRQGDCVALLMGNEPAYVWLWLGLVKLGCAMACLNYNIRAKSLLHCFQCCGAKVLLVSPELQAAVEEILPSLKKDDVSIYYVSRTSNTDGIDSFLDKVDEVSTEPIPESWRSEVTFSTPALYIYTSGTTGLPKAAMITHQRIWYGTGLTFVSGLKADDVIYITLPFYHSAALLIGIHGCIVAGATLALRTKFSASQFWDDCRKYNVTVIQYIGELLRYLCNSPQKPNDRDHKVRLALGNGLRGDVWRQFVKRFGDICIYEFYAATEGNIGFMNYARKVGAVGRVNYLQKKIITYDLIKYDVEKDEPVRDENGYCVRVPKGEVGLLVCKITQLTPFNGYAGAKAQTEKKKLRDVFKKGDLYFNSGDLLMVDHENFIYFHDRVGDTFRWKGENVATTEVADTVGLVDFVQEVNVYGVHVPDHEGRIGMASIKMKENHEFDGKKLFQHIADYLPSYARPRFLRIQDTIEITGTFKHRKMTLVEEGFNPAVIKDALYFLDDTAKMYVPMTEDIYNAISAKTLKL

Target ORF information:

RefSeq Version	NM_003645.4
Organism	Homo sapiens(human)
Definition	Homo sapiens solute carrier family 27 member 2 (SLC27A2), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_003645.4

ORF Insert Sequence:

ATGCTTTCCG CCATCTACAC AGTCCTGGCG GGACTGCTGT TCCTGCCGCT CCTGGTGAAC 
CTCTGCTGCC CATACTTCTT CCAGGACATA GGCTACTTCT TGAAGGTGGC CGCCGTGGGC 
CGGAGGGTGC GCAGCTACGG GAAGCGGCGG CCGGCGCGCA CCATCCTGCG GGCGTTCCTG 
GAGAAAGCGC GCCAGACGCC ACACAAGCCT TTTCTGCTCT TCCGCGACGA GACTCTCACC 
TACGCGCAGG TGGACCGGCG CAGCAATCAA GTGGCCCGGG CGCTGCACGA CCACCTCGGC 
CTGCGCCAGG GAGACTGCGT GGCGCTCCTT ATGGGTAACG AGCCGGCCTA CGTGTGGCTG 
TGGCTGGGGC TGGTGAAGCT GGGCTGTGCC ATGGCGTGCC TCAATTACAA CATCCGCGCG 
AAGTCCCTGC TGCACTGCTT CCAGTGCTGC GGGGCGAAGG TGCTGCTGGT GTCGCCAGAA 
CTACAAGCAG CTGTCGAAGA GATACTGCCA AGCCTTAAAA AAGATGATGT GTCCATCTAT 
TATGTGAGCA GAACTTCTAA CACAGATGGG ATTGACTCTT TCCTGGACAA AGTGGATGAA 
GTATCAACTG AACCTATCCC AGAGTCATGG AGGTCTGAAG TCACTTTTTC CACTCCTGCC 
TTATACATTT ATACTTCTGG AACCACAGGT CTTCCAAAAG CAGCCATGAT CACTCATCAG 
CGCATATGGT ATGGAACTGG CCTCACTTTT GTAAGCGGAT TGAAGGCAGA TGATGTCATC 
TATATCACTC TGCCCTTTTA CCACAGTGCT GCACTACTGA TTGGCATTCA CGGATGTATT 
GTGGCTGGTG CTACTCTTGC CTTGCGGACT AAATTTTCAG CCAGCCAGTT TTGGGATGAC 
TGCAGAAAAT ACAACGTCAC TGTCATTCAG TATATCGGTG AACTGCTTCG GTATTTATGC 
AACTCACCAC AGAAACCAAA TGACCGTGAT CATAAAGTGA GACTGGCACT GGGAAATGGC 
TTACGAGGAG ATGTGTGGAG ACAATTTGTC AAGAGATTTG GGGACATATG CATCTATGAG 
TTCTATGCTG CCACTGAAGG CAATATTGGA TTTATGAATT ATGCGAGAAA AGTTGGTGCT 
GTTGGAAGAG TAAACTACCT ACAGAAAAAA ATCATAACTT ATGACCTGAT TAAATATGAT 
GTGGAGAAAG ATGAACCTGT CCGTGATGAA AATGGATATT GCGTCAGAGT TCCCAAAGGT 
GAAGTTGGAC TTCTGGTTTG CAAAATCACA CAACTTACAC CATTTAATGG CTATGCTGGA 
GCAAAGGCTC AGACAGAGAA GAAAAAACTG AGAGATGTCT TTAAGAAAGG AGACCTCTAT 
TTCAACAGTG GAGATCTCTT AATGGTTGAC CATGAAAATT TCATCTATTT CCACGACAGA 
GTTGGAGATA CATTCCGGTG GAAAGGGGAA AATGTGGCCA CCACTGAAGT TGCTGATACA 
GTTGGACTGG TTGATTTTGT CCAAGAAGTA AATGTTTATG GAGTGCATGT GCCAGATCAT 
GAGGGTCGCA TTGGCATGGC CTCCATCAAA ATGAAAGAAA ACCATGAATT TGATGGAAAG 
AAACTCTTTC AGCACATTGC TGATTACCTA CCTAGTTATG CAAGGCCCCG GTTTCTAAGA 
ATACAGGACA CCATTGAGAT CACTGGAACT TTTAAACACC GCAAAATGAC CCTGGTGGAG 
GAGGGCTTTA ACCCTGCTGT CATCAAAGAT GCCTTGTATT TCTTGGATGA CACAGCAAAA 
ATGTATGTGC CTATGACTGA GGACATCTAT AATGCCATAA GTGCTAAAAC CCTGAAACTC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SLC27A2 ( NM_001159629.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001153101.1 Homo sapiens solute carrier family 27 member 2 (SLC27A2), transcript variant 2, mRNA.

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CloneID	OHu09179
Clone ID Related Accession (Same CDS sequence)	NM_001159629.1
Accession Version	NM_001159629.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1704bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-15
Organism	Homo sapiens(human)
Product	very long-chain acyl-CoA synthetase isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK290262.1, BC057770.1 and BM980042.1. Transcript Variant: This variant (2) is lacking an in-frame coding exon compared to variant 1, resulting in a shorter isoform (2) missing an internal protein segment compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC057770.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA1970526 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCTTTCCG CCATCTACAC AGTCCTGGCG GGACTGCTGT TCCTGCCGCT CCTGGTGAAC 
CTCTGCTGCC CATACTTCTT CCAGGACATA GGCTACTTCT TGAAGGTGGC CGCCGTGGGC 
CGGAGGGTGC GCAGCTACGG GAAGCGGCGG CCGGCGCGCA CCATCCTGCG GGCGTTCCTG 
GAGAAAGCGC GCCAGACGCC ACACAAGCCT TTTCTGCTCT TCCGCGACGA GACTCTCACC 
TACGCGCAGG TGGACCGGCG CAGCAATCAA GTGGCCCGGG CGCTGCACGA CCACCTCGGC 
CTGCGCCAGG GAGACTGCGT GGCGCTCCTT ATGGGTAACG AGCCGGCCTA CGTGTGGCTG 
TGGCTGGGGC TGGTGAAGCT GGGCTGTGCC ATGGCGTGCC TCAATTACAA CATCCGCGCG 
AAGTCCCTGC TGCACTGCTT CCAGTGCTGC GGGGCGAAGG TGCTGCTGGT GTCGCCAGAA 
CTACAAGCAG CTGTCGAAGA GATACTGCCA AGCCTTAAAA AAGATGATGT GTCCATCTAT 
TATGTGAGCA GAACTTCTAA CACAGATGGG ATTGACTCTT TCCTGGACAA AGTGGATGAA 
GTATCAACTG AACCTATCCC AGAGTCATGG AGGTCTGAAG TCACTTTTTC CACTCCTGCC 
TTATACATTT ATACTTCTGG AACCACAGGT GCTACTCTTG CCTTGCGGAC TAAATTTTCA 
GCCAGCCAGT TTTGGGATGA CTGCAGAAAA TACAACGTCA CTGTCATTCA GTATATCGGT 
GAACTGCTTC GGTATTTATG CAACTCACCA CAGAAACCAA ATGACCGTGA TCATAAAGTG 
AGACTGGCAC TGGGAAATGG CTTACGAGGA GATGTGTGGA GACAATTTGT CAAGAGATTT 
GGGGACATAT GCATCTATGA GTTCTATGCT GCCACTGAAG GCAATATTGG ATTTATGAAT 
TATGCGAGAA AAGTTGGTGC TGTTGGAAGA GTAAACTACC TACAGAAAAA AATCATAACT 
TATGACCTGA TTAAATATGA TGTGGAGAAA GATGAACCTG TCCGTGATGA AAATGGATAT 
TGCGTCAGAG TTCCCAAAGG TGAAGTTGGA CTTCTGGTTT GCAAAATCAC ACAACTTACA 
CCATTTAATG GCTATGCTGG AGCAAAGGCT CAGACAGAGA AGAAAAAACT GAGAGATGTC 
TTTAAGAAAG GAGACCTCTA TTTCAACAGT GGAGATCTCT TAATGGTTGA CCATGAAAAT 
TTCATCTATT TCCACGACAG AGTTGGAGAT ACATTCCGGT GGAAAGGGGA AAATGTGGCC 
ACCACTGAAG TTGCTGATAC AGTTGGACTG GTTGATTTTG TCCAAGAAGT AAATGTTTAT 
GGAGTGCATG TGCCAGATCA TGAGGGTCGC ATTGGCATGG CCTCCATCAA AATGAAAGAA 
AACCATGAAT TTGATGGAAA GAAACTCTTT CAGCACATTG CTGATTACCT ACCTAGTTAT 
GCAAGGCCCC GGTTTCTAAG AATACAGGAC ACCATTGAGA TCACTGGAAC TTTTAAACAC 
CGCAAAATGA CCCTGGTGGA GGAGGGCTTT AACCCTGCTG TCATCAAAGA TGCCTTGTAT 
TTCTTGGATG ACACAGCAAA AATGTATGTG CCTATGACTG AGGACATCTA TAATGCCATA 
AGTGCTAAAA CCCTGAAACT CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001153101.1
CDS	233..1936
Translation	MLSAIYTVLAGLLFLPLLVNLCCPYFFQDIGYFLKVAAVGRRVRSYGKRRPARTILRAFLEKARQTPHKPFLLFRDETLTYAQVDRRSNQVARALHDHLGLRQGDCVALLMGNEPAYVWLWLGLVKLGCAMACLNYNIRAKSLLHCFQCCGAKVLLVSPELQAAVEEILPSLKKDDVSIYYVSRTSNTDGIDSFLDKVDEVSTEPIPESWRSEVTFSTPALYIYTSGTTGATLALRTKFSASQFWDDCRKYNVTVIQYIGELLRYLCNSPQKPNDRDHKVRLALGNGLRGDVWRQFVKRFGDICIYEFYAATEGNIGFMNYARKVGAVGRVNYLQKKIITYDLIKYDVEKDEPVRDENGYCVRVPKGEVGLLVCKITQLTPFNGYAGAKAQTEKKKLRDVFKKGDLYFNSGDLLMVDHENFIYFHDRVGDTFRWKGENVATTEVADTVGLVDFVQEVNVYGVHVPDHEGRIGMASIKMKENHEFDGKKLFQHIADYLPSYARPRFLRIQDTIEITGTFKHRKMTLVEEGFNPAVIKDALYFLDDTAKMYVPMTEDIYNAISAKTLKL

Target ORF information:

RefSeq Version	NM_001159629.1
Organism	Homo sapiens(human)
Definition	Homo sapiens solute carrier family 27 member 2 (SLC27A2), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001159629.1

ORF Insert Sequence:

ATGCTTTCCG CCATCTACAC AGTCCTGGCG GGACTGCTGT TCCTGCCGCT CCTGGTGAAC 
CTCTGCTGCC CATACTTCTT CCAGGACATA GGCTACTTCT TGAAGGTGGC CGCCGTGGGC 
CGGAGGGTGC GCAGCTACGG GAAGCGGCGG CCGGCGCGCA CCATCCTGCG GGCGTTCCTG 
GAGAAAGCGC GCCAGACGCC ACACAAGCCT TTTCTGCTCT TCCGCGACGA GACTCTCACC 
TACGCGCAGG TGGACCGGCG CAGCAATCAA GTGGCCCGGG CGCTGCACGA CCACCTCGGC 
CTGCGCCAGG GAGACTGCGT GGCGCTCCTT ATGGGTAACG AGCCGGCCTA CGTGTGGCTG 
TGGCTGGGGC TGGTGAAGCT GGGCTGTGCC ATGGCGTGCC TCAATTACAA CATCCGCGCG 
AAGTCCCTGC TGCACTGCTT CCAGTGCTGC GGGGCGAAGG TGCTGCTGGT GTCGCCAGAA 
CTACAAGCAG CTGTCGAAGA GATACTGCCA AGCCTTAAAA AAGATGATGT GTCCATCTAT 
TATGTGAGCA GAACTTCTAA CACAGATGGG ATTGACTCTT TCCTGGACAA AGTGGATGAA 
GTATCAACTG AACCTATCCC AGAGTCATGG AGGTCTGAAG TCACTTTTTC CACTCCTGCC 
TTATACATTT ATACTTCTGG AACCACAGGT GCTACTCTTG CCTTGCGGAC TAAATTTTCA 
GCCAGCCAGT TTTGGGATGA CTGCAGAAAA TACAACGTCA CTGTCATTCA GTATATCGGT 
GAACTGCTTC GGTATTTATG CAACTCACCA CAGAAACCAA ATGACCGTGA TCATAAAGTG 
AGACTGGCAC TGGGAAATGG CTTACGAGGA GATGTGTGGA GACAATTTGT CAAGAGATTT 
GGGGACATAT GCATCTATGA GTTCTATGCT GCCACTGAAG GCAATATTGG ATTTATGAAT 
TATGCGAGAA AAGTTGGTGC TGTTGGAAGA GTAAACTACC TACAGAAAAA AATCATAACT 
TATGACCTGA TTAAATATGA TGTGGAGAAA GATGAACCTG TCCGTGATGA AAATGGATAT 
TGCGTCAGAG TTCCCAAAGG TGAAGTTGGA CTTCTGGTTT GCAAAATCAC ACAACTTACA 
CCATTTAATG GCTATGCTGG AGCAAAGGCT CAGACAGAGA AGAAAAAACT GAGAGATGTC 
TTTAAGAAAG GAGACCTCTA TTTCAACAGT GGAGATCTCT TAATGGTTGA CCATGAAAAT 
TTCATCTATT TCCACGACAG AGTTGGAGAT ACATTCCGGT GGAAAGGGGA AAATGTGGCC 
ACCACTGAAG TTGCTGATAC AGTTGGACTG GTTGATTTTG TCCAAGAAGT AAATGTTTAT 
GGAGTGCATG TGCCAGATCA TGAGGGTCGC ATTGGCATGG CCTCCATCAA AATGAAAGAA 
AACCATGAAT TTGATGGAAA GAAACTCTTT CAGCACATTG CTGATTACCT ACCTAGTTAT 
GCAAGGCCCC GGTTTCTAAG AATACAGGAC ACCATTGAGA TCACTGGAAC TTTTAAACAC 
CGCAAAATGA CCCTGGTGGA GGAGGGCTTT AACCCTGCTG TCATCAAAGA TGCCTTGTAT 
TTCTTGGATG ACACAGCAAA AATGTATGTG CCTATGACTG AGGACATCTA TAATGCCATA 
AGTGCTAAAA CCCTGAAACT CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Protein expression of fatty acid transporter 2 is polarized to the trophoblast basal plasma membrane and increased in placentas from overweight/obese women.
Placenta4060-6(2016 Apr)
Lager S,Ramirez VI,Gaccioli F,Jang B,Jansson T,Powell TL

Fatty acid transport protein-2 inhibitor Grassofermata/CB5 protects cells against lipid accumulation and toxicity.
Biochemical and biophysical research communications465(3)534-41(2015 Sep)
Saini N,Black PN,Montefusco D,DiRusso CC

Influence of breastfeeding on blood-cell transcript-based biomarkers of health in children.
Pediatric obesity9(6)463-70(2014 Dec)
Priego T,S?nchez J,Pic? C,Ahrens W,Bammann K,De Henauw S,Fraterman A,Iacoviello L,Lissner L,Moln?r D,Moreno LA,Siani A,Tornaritis M,Veidebaum T,Palou A,

An atlas of genetic influences on human blood metabolites.
Nature genetics46(6)543-550(2014 Jun)
Shin SY,Fauman EB,Petersen AK,Krumsiek J,Santos R,Huang J,Arnold M,Erte I,Forgetta V,Yang TP,Walter K,Menni C,Chen L,Vasquez L,Valdes AM,Hyde CL,Wang V,Ziemek D,Roberts P,Xi L,Grundberg E,,Waldenberger M,Richards JB,Mohney RP,Milburn MV,John SL,Trimmer J,Theis FJ,Overington JP,Suhre K,Brosnan MJ,Gieger C,Kastenm?ller G,Spector TD,Soranzo N

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SLC27A2 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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