ADARB2 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	ADARB2
Entrez Gene ID	105
Full Name	adenosine deaminase, RNA specific B2 (inactive)
Synonyms	ADAR3,RED2
General protein information	Preferred Names adenosine deaminase, RNA specific B2 (inactive) Names double-stranded RNA-specific editase B2 RED2 homolog RNA-dependent adenosine deaminase 3 RNA-editing deaminase 2 RNA-editing enzyme 2 adenosine deaminase, RNA-specific, B2 (RED1 homolog rat) adenosine deaminase, RNA-specific, B2 (RED2 homolog rat) adenosine deaminase, RNA-specific, B2 (non-functional) dsRNA adenosine deaminase B2 homolog of rat BLUE
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 10 Map Location: 10p15.3
Summary	This gene encodes a member of the double-stranded RNA adenosine deaminase family of RNA-editing enzymes and may play a regulatory role in RNA editing. [provided by RefSeq, Jul 2008].
Disorder MIM:	602065

mRNA and Protein(s)

mRNA	Protein	Name
NM_018702.3	NP_061172.1	double-stranded RNA-specific editase B2
NM_018702.4	NP_061172.1	double-stranded RNA-specific editase B2

Pathways from BioSystems

Homologies

Homo sapiens (human)	ADARB2	NP_061172.1
Gallus gallus (chicken)	ADARB2	XP_418563.4
Danio rerio (zebrafish)	adarb2	XP_686426.5
Pan troglodytes (chimpanzee)	ADARB2	XP_003312479.1
Mus musculus (house mouse)	Adarb2	NP_443209.2
Canis lupus familiaris (dog)	ADARB2	XP_005617264.1
Bos taurus (cattle)	ADARB2	NP_001179517.1
Xenopus tropicalis (tropical clawed frog)	adarb2	XP_002935222.2
Rattus norvegicus (Norway rat)	Adarb2	NP_579836.1

Gene Ontology
Bibliography

Related articles in PubMed

Adenosine Deaminase That Acts on RNA 3 (ADAR3) Binding to Glutamate Receptor Subunit B Pre-mRNA Inhibits RNA Editing in Glioblastoma.
Oakes E, Anderson A, Cohen-Gadol A, Hundley HA
The Journal of biological chemistry292(10)4326-4335(2017 03)

Gene-smoking interactions identify several novel blood pressure loci in the Framingham Heart Study.
Sung YJ, de Las Fuentes L, Schwander KL, Simino J, Rao DC
American journal of hypertension28(3)343-54(2015 Mar)

Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche.
Perry JR, Day F, Elks CE, Sulem P, Thompson DJ, Ferreira T, He C, Chasman DI, Esko T, Thorleifsson G, Albrecht E, Ang WQ, Corre T, Cousminer DL, Feenstra B, Franceschini N, Ganna A, Johnson AD, Kjellqvist S, Lunetta KL, McMahon G, Nolte IM, Paternoster L, Porcu E, Smith AV, Stolk L, Teumer A, T?ernikova N, Tikkanen E, Ulivi S, Wagner EK, Amin N, Bierut LJ, Byrne EM, Hottenga JJ, Koller DL, Mangino M, Pers TH, Yerges-Armstrong LM, Zhao JH, Andrulis IL, Anton-Culver H, Atsma F, Bandinelli S, Beckmann MW, Benitez J, Blomqvist C, Bojesen SE, Bolla MK, Bonanni B, Brauch H, Brenner H, Buring JE, Chang-Claude J, Chanock S, Chen J, Chenevix-Trench G, Coll?e JM, Couch FJ, Couper D, Coveillo AD, Cox A, Czene K, D'adamo AP, Smith GD, De Vivo I, Demerath EW, Dennis J, Devilee P, Dieffenbach AK, Dunning AM, Eiriksdottir G, Eriksson JG, Fasching PA, Ferrucci L, Flesch-Janys D, Flyger H, Foroud T, Franke L, Garcia ME, Garc?a-Closas M, Geller F, de Geus EE, Giles GG, Gudbjartsson DF, Gudnason V, Gu?nel P, Guo S, Hall P, Hamann U, Haring R, Hartman CA, Heath AC, Hofman A, Hooning MJ, Hopper JL, Hu FB, Hunter DJ, Karasik D, Kiel DP, Knight JA, Kosma VM, Kutalik Z, Lai S, Lambrechts D, Lindblom A, M?gi R, Magnusson PK, Mannermaa A, Martin NG, Masson G, McArdle PF, McArdle WL, Melbye M, Michailidou K, Mihailov E, Milani L, Milne RL, Nevanlinna H, Neven P, Nohr EA, Oldehinkel AJ, Oostra BA, Palotie A, Peacock M, Pedersen NL, Peterlongo P, Peto J, Pharoah PD, Postma DS, Pouta A, Pylk?s K, Radice P, Ring S, Rivadeneira F, Robino A, Rose LM, Rudolph A, Salomaa V, Sanna S, Schlessinger D, Schmidt MK, Southey MC, Sovio U, Stampfer MJ, St?ckl D, Storniolo AM, Timpson NJ, Tyrer J, Visser JA, Vollenweider P, V?lzke H, Waeber G, Waldenberger M, Wallaschofski H, Wang Q, Willemsen G, Winqvist R, Wolffenbuttel BH, Wright MJ, , , , , , , Boomsma DI, Econs MJ, Khaw KT, Loos RJ, McCarthy MI, Montgomery GW, Rice JP, Streeten EA, Thorsteinsdottir U, van Duijn CM, Alizadeh BZ, Bergmann S, Boerwinkle E, Boyd HA, Crisponi L, Gasparini P, Gieger C, Harris TB, Ingelsson E, J?rvelin MR, Kraft P, Lawlor D, Metspalu A, Pennell CE, Ridker PM, Snieder H, S?rensen TI, Spector TD, Strachan DP, Uitterlinden AG, Wareham NJ, Widen E, Zygmunt M, Murray A, Easton DF, Stefansson K, Murabito JM, Ong KK
Nature514(7520)92-97(2014 Oct)

Genome-wide meta-analysis identifies new susceptibility loci for migraine.
Anttila V, Winsvold BS, Gormley P, Kurth T, Bettella F, McMahon G, Kallela M, Malik R, de Vries B, Terwindt G, Medland SE, Todt U, McArdle WL, Quaye L, Koiranen M, Ikram MA, Lehtim?ki T, Stam AH, Ligthart L, Wedenoja J, Dunham I, Neale BM, Palta P, Hamalainen E, Sch?rks M, Rose LM, Buring JE, Ridker PM, Steinberg S, Stefansson H, Jakobsson F, Lawlor DA, Evans DM, Ring SM, F?rkkil? M, Artto V, Kaunisto MA, Freilinger T, Schoenen J, Frants RR, Pelzer N, Weller CM, Zielman R, Heath AC, Madden PAF, Montgomery GW, Martin NG, Borck G, G?bel H, Heinze A, Heinze-Kuhn K, Williams FMK, Hartikainen AL, Pouta A, van den Ende J, Uitterlinden AG, Hofman A, Amin N, Hottenga JJ, Vink JM, Heikkil? K, Alexander M, Muller-Myhsok B, Schreiber S, Meitinger T, Wichmann HE, Aromaa A, Eriksson JG, Traynor B, Trabzuni D, , , Rossin E, Lage K, Jacobs SBR, Gibbs JR, Birney E, Kaprio J, Penninx BW, Boomsma DI, van Duijn C, Raitakari O, Jarvelin MR, Zwart JA, Cherkas L, Strachan DP, Kubisch C, Ferrari MD, van den Maagdenberg AMJM, Dichgans M, Wessman M, Smith GD, Stefansson K, Daly MJ, Nyholt DR, Chasman D, Palotie A
Nature genetics45(8)912-917(2013 Aug)

Genome wide association study (GWAS) of Chagas cardiomyopathy in Trypanosoma cruzi seropositive subjects.
Deng X, Sabino EC, Cunha-Neto E, Ribeiro AL, Ianni B, Mady C, Busch MP, Seielstad M,
PloS one8(11)e79629(2013)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

High ADAR3 expression is associated with Glioblastoma.
Title: Adenosine Deaminase That Acts on RNA 3 (ADAR3) Binding to Glutamate Receptor Subunit B Pre-mRNA Inhibits RNA Editing in Glioblastoma.

The SNP in ADARB2 related to longevity is associated with metabolic disorders. This finding suggests that genetic factors modulate human longevity via the regulation of metabolic factors such as abdominal obesity and lipid profiles.
Title: A single nucleotide polymorphism of the adenosine deaminase, RNA-specific gene is associated with the serum triglyceride level, abdominal circumference, and serum adiponectin concentration.

Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)
Title: Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.

Observational study of gene-disease association. (HuGE Navigator)
Title: RNA editing genes associated with extreme old age in humans and with lifespan in C. elegans.

Observational study of gene-disease association. (HuGE Navigator)
Title: A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease.

The following ADARB2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ADARB2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu22812	NM_018702.4 Latest version!	Homo sapiens adenosine deaminase RNA specific B2 (inactive) (ADARB2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$279.50-$391.30 $559.00
View Old Accession Versions >>
OHu22812	NM_018702.3	Homo sapiens adenosine deaminase, RNA specific B2 (inactive) (ADARB2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$279.50-$391.30 $559.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

ADARB2 ( NM_018702.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_061172.1 Homo sapiens adenosine deaminase, RNA specific B2 (inactive) (ADARB2), mRNA.

Price & Availability↑

CloneID	OHu22812
Clone ID Related Accession (Same CDS sequence)	NM_018702.3 , NM_018702.4
Accession Version	NM_018702.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2220bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Homo sapiens(human)
Product	double-stranded RNA-specific editase B2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AF034837.1, BC140852.1 and AL392083.17. On Jun 1, 2011 this sequence version replaced NM_018702.2. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF034837.1, BC137477.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2157437, SAMN03465403 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCCTCGG TCCTGGGGAG CGGCAGAGGG TCTGGAGGGC TGAGCAGTCA ACTCAAATGC 
AAGTCCAAGA GGAGGAGGAG GCGGAGGTCC AAGCGGAAAG ATAAAGTAAG CATATTGTCA 
ACCTTCCTCG CTCCTTTCAA GCACCTGAGT CCTGGCATCA CAAACACGGA GGATGACGAC 
ACCCTCAGTA CCAGCAGCGC GGAGGTGAAG GAGAACCGCA ACGTGGGCAA CCTGGCCGCG 
CGGCCACCGC CCTCCGGGGA CCGGGCCCGG GGCGGCGCGC CCGGCGCGAA GAGGAAGCGG 
CCGCTGGAGG AGGGGAATGG GGGCCACTTG TGCAAACTGC AGCTGGTCTG GAAGAAGCTG 
TCGTGGTCGG TGGCGCCCAA GAACGCGCTG GTGCAGCTGC ACGAGCTGAG GCCGGGCCTG 
CAGTACCGGA CAGTGTCGCA GACGGGCCCG GTGCATGCCC CGGTCTTCGC GGTAGCGGTG 
GAGGTGAACG GGCTCACGTT CGAGGGCACA GGCCCCACCA AGAAGAAGGC CAAGATGCGC 
GCGGCGGAGC TGGCACTCAG GTCCTTCGTG CAGTTCCCCA ACGCCTGCCA GGCGCACCTG 
GCCATGGGCG GGGGCCCGGG CCCCGGCACG GACTTCACCT CCGACCAGGC CGATTTCCCC 
GACACGCTCT TCCAGGAGTT CGAGCCCCCG GCGCCGCGCC CCGGACTCGC GGGAGGCCGC 
CCCGGGGACG CCGCGCTTCT GTCCGCGGCC TACGGGCGAC GGCGGCTGCT GTGCCGCGCG 
CTGGACCTGG TGGGCCCGAC CCCCGCCACC CCCGCGGCCC CGGGCGAGCG CAACCCCGTG 
GTGCTGCTGA ACCGCCTGCG CGCCGGGCTG CGCTACGTGT GTCTGGCAGA ACCGGCCGAG 
CGGCGCGCGC GGAGCTTCGT GATGGCCGTG AGCGTGGACG GCAGGACGTT CGAGGGCTCG 
GGGCGCAGCA AGAAGCTGGC CCGGGGTCAG GCCGCGCAGG CCGCACTGCA GGAGCTGTTC 
GACATCCAGA TGCCCGGCCA CGCGCCCGGC AGGGCCAGGA GGACGCCAAT GCCGCAGGAA 
TTCGCAGACT CCATATCCCA GCTGGTCACA CAGAAGTTCC GCGAGGTGAC GACGGACCTC 
ACGCCCATGC ACGCCCGCCA TAAAGCGCTG GCAGGAATCG TCATGACCAA AGGCCTGGAT 
GCTCGGCAGG CGCAGGTCGT GGCCCTGTCC TCGGGGACCA AGTGCATCAG CGGCGAGCAC 
CTCAGTGACC AGGGGCTGGT GGTGAATGAC TGCCACGCGG AGGTCGTGGC CCGGCGGGCG 
TTCCTGCACT TCCTCTACAC GCAGCTGGAG CTGCACCTGA GCAAGCGGCG CGAGGACTCA 
GAGCGATCGA TATTCGTGCG GTTAAAAGAA GGTGGCTACC GGCTGCGAGA GAACATCCTC 
TTCCATCTCT ACGTGAGCAC CTCCCCCTGT GGAGACGCAA GACTCCACTC TCCCTACGAG 
ATCACCACAG ACCTGCACAG CAGCAAACAC CTCGTCAGGA AGTTCCGCGG GCACCTGCGC 
ACCAAGATCG AGTCCGGGGA AGGGACGGTC CCCGTGCGTG GCCCCAGCGC AGTGCAGACC 
TGGGACGGCG TCCTGCTGGG GGAGCAGCTG ATCACCATGT CCTGCACGGA CAAGATCGCC 
AGGTGGAACG TCCTGGGGCT GCAGGGCGCG CTCCTGTCCC ACTTCGTGGA GCCCGTGTAC 
CTGCAGAGCA TCGTGGTGGG CAGCCTGCAC CACACGGGCC ACCTCGCACG CGTCATGAGC 
CACCGCATGG AGGGTGTCGG CCAGCTGCCC GCCTCCTACC GGCACAACCG GCCTCTCCTC 
AGCGGCGTGA GTGACGCCGA GGCGCGCCAG CCGGGGAAGT CGCCCCCCTT CAGCATGAAC 
TGGGTCGTGG GCAGCGCGGA CCTGGAGATT ATCAACGCCA CCACTGGGCG GAGGAGCTGT 
GGGGGCCCAT CCCGGCTCTG CAAGCACGTG CTGTCTGCAC GGTGGGCGCG GCTGTATGGC 
AGGCTGAGCA CACGGACACC CAGCCCTGGA GACACGCCCT CCATGTACTG TGAGGCCAAG 
CTGGGGGCGC ACACCTACCA GTCTGTGAAA CAGCAGCTGT TCAAGGCCTT TCAGAAGGCT 
GGCCTGGGCA CCTGGGTGAG GAAACCACCG GAGCAGCAGC AGTTTCTACT GACTCTCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_061172.1
CDS	327..2546
Translation	MASVLGSGRGSGGLSSQLKCKSKRRRRRRSKRKDKVSILSTFLAPFKHLSPGITNTEDDDTLSTSSAEVKENRNVGNLAARPPPSGDRARGGAPGAKRKRPLEEGNGGHLCKLQLVWKKLSWSVAPKNALVQLHELRPGLQYRTVSQTGPVHAPVFAVAVEVNGLTFEGTGPTKKKAKMRAAELALRSFVQFPNACQAHLAMGGGPGPGTDFTSDQADFPDTLFQEFEPPAPRPGLAGGRPGDAALLSAAYGRRRLLCRALDLVGPTPATPAAPGERNPVVLLNRLRAGLRYVCLAEPAERRARSFVMAVSVDGRTFEGSGRSKKLARGQAAQAALQELFDIQMPGHAPGRARRTPMPQEFADSISQLVTQKFREVTTDLTPMHARHKALAGIVMTKGLDARQAQVVALSSGTKCISGEHLSDQGLVVNDCHAEVVARRAFLHFLYTQLELHLSKRREDSERSIFVRLKEGGYRLRENILFHLYVSTSPCGDARLHSPYEITTDLHSSKHLVRKFRGHLRTKIESGEGTVPVRGPSAVQTWDGVLLGEQLITMSCTDKIARWNVLGLQGALLSHFVEPVYLQSIVVGSLHHTGHLARVMSHRMEGVGQLPASYRHNRPLLSGVSDAEARQPGKSPPFSMNWVVGSADLEIINATTGRRSCGGPSRLCKHVLSARWARLYGRLSTRTPSPGDTPSMYCEAKLGAHTYQSVKQQLFKAFQKAGLGTWVRKPPEQQQFLLTL

Target ORF information:

RefSeq Version	NM_018702.3
Organism	Homo sapiens(human)
Definition	Homo sapiens adenosine deaminase, RNA specific B2 (inactive) (ADARB2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_018702.3

ORF Insert Sequence:

ATGGCCTCGG TCCTGGGGAG CGGCAGAGGG TCTGGAGGGC TGAGCAGTCA ACTCAAATGC 
AAGTCCAAGA GGAGGAGGAG GCGGAGGTCC AAGCGGAAAG ATAAAGTAAG CATATTGTCA 
ACCTTCCTCG CTCCTTTCAA GCACCTGAGT CCTGGCATCA CAAACACGGA GGATGACGAC 
ACCCTCAGTA CCAGCAGCGC GGAGGTGAAG GAGAACCGCA ACGTGGGCAA CCTGGCCGCG 
CGGCCACCGC CCTCCGGGGA CCGGGCCCGG GGCGGCGCGC CCGGCGCGAA GAGGAAGCGG 
CCGCTGGAGG AGGGGAATGG GGGCCACTTG TGCAAACTGC AGCTGGTCTG GAAGAAGCTG 
TCGTGGTCGG TGGCGCCCAA GAACGCGCTG GTGCAGCTGC ACGAGCTGAG GCCGGGCCTG 
CAGTACCGGA CAGTGTCGCA GACGGGCCCG GTGCATGCCC CGGTCTTCGC GGTAGCGGTG 
GAGGTGAACG GGCTCACGTT CGAGGGCACA GGCCCCACCA AGAAGAAGGC CAAGATGCGC 
GCGGCGGAGC TGGCACTCAG GTCCTTCGTG CAGTTCCCCA ACGCCTGCCA GGCGCACCTG 
GCCATGGGCG GGGGCCCGGG CCCCGGCACG GACTTCACCT CCGACCAGGC CGATTTCCCC 
GACACGCTCT TCCAGGAGTT CGAGCCCCCG GCGCCGCGCC CCGGACTCGC GGGAGGCCGC 
CCCGGGGACG CCGCGCTTCT GTCCGCGGCC TACGGGCGAC GGCGGCTGCT GTGCCGCGCG 
CTGGACCTGG TGGGCCCGAC CCCCGCCACC CCCGCGGCCC CGGGCGAGCG CAACCCCGTG 
GTGCTGCTGA ACCGCCTGCG CGCCGGGCTG CGCTACGTGT GTCTGGCAGA ACCGGCCGAG 
CGGCGCGCGC GGAGCTTCGT GATGGCCGTG AGCGTGGACG GCAGGACGTT CGAGGGCTCG 
GGGCGCAGCA AGAAGCTGGC CCGGGGTCAG GCCGCGCAGG CCGCACTGCA GGAGCTGTTC 
GACATCCAGA TGCCCGGCCA CGCGCCCGGC AGGGCCAGGA GGACGCCAAT GCCGCAGGAA 
TTCGCAGACT CCATATCCCA GCTGGTCACA CAGAAGTTCC GCGAGGTGAC GACGGACCTC 
ACGCCCATGC ACGCCCGCCA TAAAGCGCTG GCAGGAATCG TCATGACCAA AGGCCTGGAT 
GCTCGGCAGG CGCAGGTCGT GGCCCTGTCC TCGGGGACCA AGTGCATCAG CGGCGAGCAC 
CTCAGTGACC AGGGGCTGGT GGTGAATGAC TGCCACGCGG AGGTCGTGGC CCGGCGGGCG 
TTCCTGCACT TCCTCTACAC GCAGCTGGAG CTGCACCTGA GCAAGCGGCG CGAGGACTCA 
GAGCGATCGA TATTCGTGCG GTTAAAAGAA GGTGGCTACC GGCTGCGAGA GAACATCCTC 
TTCCATCTCT ACGTGAGCAC CTCCCCCTGT GGAGACGCAA GACTCCACTC TCCCTACGAG 
ATCACCACAG ACCTGCACAG CAGCAAACAC CTCGTCAGGA AGTTCCGCGG GCACCTGCGC 
ACCAAGATCG AGTCCGGGGA AGGGACGGTC CCCGTGCGTG GCCCCAGCGC AGTGCAGACC 
TGGGACGGCG TCCTGCTGGG GGAGCAGCTG ATCACCATGT CCTGCACGGA CAAGATCGCC 
AGGTGGAACG TCCTGGGGCT GCAGGGCGCG CTCCTGTCCC ACTTCGTGGA GCCCGTGTAC 
CTGCAGAGCA TCGTGGTGGG CAGCCTGCAC CACACGGGCC ACCTCGCACG CGTCATGAGC 
CACCGCATGG AGGGTGTCGG CCAGCTGCCC GCCTCCTACC GGCACAACCG GCCTCTCCTC 
AGCGGCGTGA GTGACGCCGA GGCGCGCCAG CCGGGGAAGT CGCCCCCCTT CAGCATGAAC 
TGGGTCGTGG GCAGCGCGGA CCTGGAGATT ATCAACGCCA CCACTGGGCG GAGGAGCTGT 
GGGGGCCCAT CCCGGCTCTG CAAGCACGTG CTGTCTGCAC GGTGGGCGCG GCTGTATGGC 
AGGCTGAGCA CACGGACACC CAGCCCTGGA GACACGCCCT CCATGTACTG TGAGGCCAAG 
CTGGGGGCGC ACACCTACCA GTCTGTGAAA CAGCAGCTGT TCAAGGCCTT TCAGAAGGCT 
GGCCTGGGCA CCTGGGTGAG GAAACCACCG GAGCAGCAGC AGTTTCTACT GACTCTCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ADARB2 ( NM_018702.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_061172.1 Homo sapiens adenosine deaminase RNA specific B2 (inactive) (ADARB2), mRNA.

Price & Availability↑

CloneID	OHu22812
Clone ID Related Accession (Same CDS sequence)	NM_018702.3 , NM_018702.4
Accession Version	NM_018702.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2220bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Homo sapiens(human)
Product	double-stranded RNA-specific editase B2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC026224.6, AF034837.1, BC140852.1 and AL392083.17. On Nov 23, 2018 this sequence version replaced NM_018702.3. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF034837.1, BC137477.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2157437, SAMN03465403 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000381312.6/ ENSP00000370713.1 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCCTCGG TCCTGGGGAG CGGCAGAGGG TCTGGAGGGC TGAGCAGTCA ACTCAAATGC 
AAGTCCAAGA GGAGGAGGAG GCGGAGGTCC AAGCGGAAAG ATAAAGTAAG CATATTGTCA 
ACCTTCCTCG CTCCTTTCAA GCACCTGAGT CCTGGCATCA CAAACACGGA GGATGACGAC 
ACCCTCAGTA CCAGCAGCGC GGAGGTGAAG GAGAACCGCA ACGTGGGCAA CCTGGCCGCG 
CGGCCACCGC CCTCCGGGGA CCGGGCCCGG GGCGGCGCGC CCGGCGCGAA GAGGAAGCGG 
CCGCTGGAGG AGGGGAATGG GGGCCACTTG TGCAAACTGC AGCTGGTCTG GAAGAAGCTG 
TCGTGGTCGG TGGCGCCCAA GAACGCGCTG GTGCAGCTGC ACGAGCTGAG GCCGGGCCTG 
CAGTACCGGA CAGTGTCGCA GACGGGCCCG GTGCATGCCC CGGTCTTCGC GGTAGCGGTG 
GAGGTGAACG GGCTCACGTT CGAGGGCACA GGCCCCACCA AGAAGAAGGC CAAGATGCGC 
GCGGCGGAGC TGGCACTCAG GTCCTTCGTG CAGTTCCCCA ACGCCTGCCA GGCGCACCTG 
GCCATGGGCG GGGGCCCGGG CCCCGGCACG GACTTCACCT CCGACCAGGC CGATTTCCCC 
GACACGCTCT TCCAGGAGTT CGAGCCCCCG GCGCCGCGCC CCGGACTCGC GGGAGGCCGC 
CCCGGGGACG CCGCGCTTCT GTCCGCGGCC TACGGGCGAC GGCGGCTGCT GTGCCGCGCG 
CTGGACCTGG TGGGCCCGAC CCCCGCCACC CCCGCGGCCC CGGGCGAGCG CAACCCCGTG 
GTGCTGCTGA ACCGCCTGCG CGCCGGGCTG CGCTACGTGT GTCTGGCAGA ACCGGCCGAG 
CGGCGCGCGC GGAGCTTCGT GATGGCCGTG AGCGTGGACG GCAGGACGTT CGAGGGCTCG 
GGGCGCAGCA AGAAGCTGGC CCGGGGTCAG GCCGCGCAGG CCGCACTGCA GGAGCTGTTC 
GACATCCAGA TGCCCGGCCA CGCGCCCGGC AGGGCCAGGA GGACGCCAAT GCCGCAGGAA 
TTCGCAGACT CCATATCCCA GCTGGTCACA CAGAAGTTCC GCGAGGTGAC GACGGACCTC 
ACGCCCATGC ACGCCCGCCA TAAAGCGCTG GCAGGAATCG TCATGACCAA AGGCCTGGAT 
GCTCGGCAGG CGCAGGTCGT GGCCCTGTCC TCGGGGACCA AGTGCATCAG CGGCGAGCAC 
CTCAGTGACC AGGGGCTGGT GGTGAATGAC TGCCACGCGG AGGTCGTGGC CCGGCGGGCG 
TTCCTGCACT TCCTCTACAC GCAGCTGGAG CTGCACCTGA GCAAGCGGCG CGAGGACTCA 
GAGCGATCGA TATTCGTGCG GTTAAAAGAA GGTGGCTACC GGCTGCGAGA GAACATCCTC 
TTCCATCTCT ACGTGAGCAC CTCCCCCTGT GGAGACGCAA GACTCCACTC TCCCTACGAG 
ATCACCACAG ACCTGCACAG CAGCAAACAC CTCGTCAGGA AGTTCCGCGG GCACCTGCGC 
ACCAAGATCG AGTCCGGGGA AGGGACGGTC CCCGTGCGTG GCCCCAGCGC AGTGCAGACC 
TGGGACGGCG TCCTGCTGGG GGAGCAGCTG ATCACCATGT CCTGCACGGA CAAGATCGCC 
AGGTGGAACG TCCTGGGGCT GCAGGGCGCG CTCCTGTCCC ACTTCGTGGA GCCCGTGTAC 
CTGCAGAGCA TCGTGGTGGG CAGCCTGCAC CACACGGGCC ACCTCGCACG CGTCATGAGC 
CACCGCATGG AGGGTGTCGG CCAGCTGCCC GCCTCCTACC GGCACAACCG GCCTCTCCTC 
AGCGGCGTGA GTGACGCCGA GGCGCGCCAG CCGGGGAAGT CGCCCCCCTT CAGCATGAAC 
TGGGTCGTGG GCAGCGCGGA CCTGGAGATT ATCAACGCCA CCACTGGGCG GAGGAGCTGT 
GGGGGCCCAT CCCGGCTCTG CAAGCACGTG CTGTCTGCAC GGTGGGCGCG GCTGTATGGC 
AGGCTGAGCA CACGGACACC CAGCCCTGGA GACACGCCCT CCATGTACTG TGAGGCCAAG 
CTGGGGGCGC ACACCTACCA GTCTGTGAAA CAGCAGCTGT TCAAGGCCTT TCAGAAGGCT 
GGCCTGGGCA CCTGGGTGAG GAAACCACCG GAGCAGCAGC AGTTTCTACT GACTCTCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_061172.1
CDS	376..2595
Translation	MASVLGSGRGSGGLSSQLKCKSKRRRRRRSKRKDKVSILSTFLAPFKHLSPGITNTEDDDTLSTSSAEVKENRNVGNLAARPPPSGDRARGGAPGAKRKRPLEEGNGGHLCKLQLVWKKLSWSVAPKNALVQLHELRPGLQYRTVSQTGPVHAPVFAVAVEVNGLTFEGTGPTKKKAKMRAAELALRSFVQFPNACQAHLAMGGGPGPGTDFTSDQADFPDTLFQEFEPPAPRPGLAGGRPGDAALLSAAYGRRRLLCRALDLVGPTPATPAAPGERNPVVLLNRLRAGLRYVCLAEPAERRARSFVMAVSVDGRTFEGSGRSKKLARGQAAQAALQELFDIQMPGHAPGRARRTPMPQEFADSISQLVTQKFREVTTDLTPMHARHKALAGIVMTKGLDARQAQVVALSSGTKCISGEHLSDQGLVVNDCHAEVVARRAFLHFLYTQLELHLSKRREDSERSIFVRLKEGGYRLRENILFHLYVSTSPCGDARLHSPYEITTDLHSSKHLVRKFRGHLRTKIESGEGTVPVRGPSAVQTWDGVLLGEQLITMSCTDKIARWNVLGLQGALLSHFVEPVYLQSIVVGSLHHTGHLARVMSHRMEGVGQLPASYRHNRPLLSGVSDAEARQPGKSPPFSMNWVVGSADLEIINATTGRRSCGGPSRLCKHVLSARWARLYGRLSTRTPSPGDTPSMYCEAKLGAHTYQSVKQQLFKAFQKAGLGTWVRKPPEQQQFLLTL

Target ORF information:

RefSeq Version	NM_018702.4
Organism	Homo sapiens(human)
Definition	Homo sapiens adenosine deaminase RNA specific B2 (inactive) (ADARB2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_018702.4

ORF Insert Sequence:

ATGGCCTCGG TCCTGGGGAG CGGCAGAGGG TCTGGAGGGC TGAGCAGTCA ACTCAAATGC 
AAGTCCAAGA GGAGGAGGAG GCGGAGGTCC AAGCGGAAAG ATAAAGTAAG CATATTGTCA 
ACCTTCCTCG CTCCTTTCAA GCACCTGAGT CCTGGCATCA CAAACACGGA GGATGACGAC 
ACCCTCAGTA CCAGCAGCGC GGAGGTGAAG GAGAACCGCA ACGTGGGCAA CCTGGCCGCG 
CGGCCACCGC CCTCCGGGGA CCGGGCCCGG GGCGGCGCGC CCGGCGCGAA GAGGAAGCGG 
CCGCTGGAGG AGGGGAATGG GGGCCACTTG TGCAAACTGC AGCTGGTCTG GAAGAAGCTG 
TCGTGGTCGG TGGCGCCCAA GAACGCGCTG GTGCAGCTGC ACGAGCTGAG GCCGGGCCTG 
CAGTACCGGA CAGTGTCGCA GACGGGCCCG GTGCATGCCC CGGTCTTCGC GGTAGCGGTG 
GAGGTGAACG GGCTCACGTT CGAGGGCACA GGCCCCACCA AGAAGAAGGC CAAGATGCGC 
GCGGCGGAGC TGGCACTCAG GTCCTTCGTG CAGTTCCCCA ACGCCTGCCA GGCGCACCTG 
GCCATGGGCG GGGGCCCGGG CCCCGGCACG GACTTCACCT CCGACCAGGC CGATTTCCCC 
GACACGCTCT TCCAGGAGTT CGAGCCCCCG GCGCCGCGCC CCGGACTCGC GGGAGGCCGC 
CCCGGGGACG CCGCGCTTCT GTCCGCGGCC TACGGGCGAC GGCGGCTGCT GTGCCGCGCG 
CTGGACCTGG TGGGCCCGAC CCCCGCCACC CCCGCGGCCC CGGGCGAGCG CAACCCCGTG 
GTGCTGCTGA ACCGCCTGCG CGCCGGGCTG CGCTACGTGT GTCTGGCAGA ACCGGCCGAG 
CGGCGCGCGC GGAGCTTCGT GATGGCCGTG AGCGTGGACG GCAGGACGTT CGAGGGCTCG 
GGGCGCAGCA AGAAGCTGGC CCGGGGTCAG GCCGCGCAGG CCGCACTGCA GGAGCTGTTC 
GACATCCAGA TGCCCGGCCA CGCGCCCGGC AGGGCCAGGA GGACGCCAAT GCCGCAGGAA 
TTCGCAGACT CCATATCCCA GCTGGTCACA CAGAAGTTCC GCGAGGTGAC GACGGACCTC 
ACGCCCATGC ACGCCCGCCA TAAAGCGCTG GCAGGAATCG TCATGACCAA AGGCCTGGAT 
GCTCGGCAGG CGCAGGTCGT GGCCCTGTCC TCGGGGACCA AGTGCATCAG CGGCGAGCAC 
CTCAGTGACC AGGGGCTGGT GGTGAATGAC TGCCACGCGG AGGTCGTGGC CCGGCGGGCG 
TTCCTGCACT TCCTCTACAC GCAGCTGGAG CTGCACCTGA GCAAGCGGCG CGAGGACTCA 
GAGCGATCGA TATTCGTGCG GTTAAAAGAA GGTGGCTACC GGCTGCGAGA GAACATCCTC 
TTCCATCTCT ACGTGAGCAC CTCCCCCTGT GGAGACGCAA GACTCCACTC TCCCTACGAG 
ATCACCACAG ACCTGCACAG CAGCAAACAC CTCGTCAGGA AGTTCCGCGG GCACCTGCGC 
ACCAAGATCG AGTCCGGGGA AGGGACGGTC CCCGTGCGTG GCCCCAGCGC AGTGCAGACC 
TGGGACGGCG TCCTGCTGGG GGAGCAGCTG ATCACCATGT CCTGCACGGA CAAGATCGCC 
AGGTGGAACG TCCTGGGGCT GCAGGGCGCG CTCCTGTCCC ACTTCGTGGA GCCCGTGTAC 
CTGCAGAGCA TCGTGGTGGG CAGCCTGCAC CACACGGGCC ACCTCGCACG CGTCATGAGC 
CACCGCATGG AGGGTGTCGG CCAGCTGCCC GCCTCCTACC GGCACAACCG GCCTCTCCTC 
AGCGGCGTGA GTGACGCCGA GGCGCGCCAG CCGGGGAAGT CGCCCCCCTT CAGCATGAAC 
TGGGTCGTGG GCAGCGCGGA CCTGGAGATT ATCAACGCCA CCACTGGGCG GAGGAGCTGT 
GGGGGCCCAT CCCGGCTCTG CAAGCACGTG CTGTCTGCAC GGTGGGCGCG GCTGTATGGC 
AGGCTGAGCA CACGGACACC CAGCCCTGGA GACACGCCCT CCATGTACTG TGAGGCCAAG 
CTGGGGGCGC ACACCTACCA GTCTGTGAAA CAGCAGCTGT TCAAGGCCTT TCAGAAGGCT 
GGCCTGGGCA CCTGGGTGAG GAAACCACCG GAGCAGCAGC AGTTTCTACT GACTCTCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

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