IFITM3 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	IFITM3
Entrez Gene ID	10410
Full Name	interferon induced transmembrane protein 3
Synonyms	1-8U,DSPA2b,IP15
General protein information	Preferred Names interferon induced transmembrane protein 3 Names interferon-induced transmembrane protein 3 dispanin subfamily A member 2b interferon-inducible protein 1-8U
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 11 Map Location: 11p15.5
Summary	The protein encoded by this gene is an interferon-induced membrane protein that helps confer immunity to influenza A H1N1 virus, West Nile virus, and dengue virus. Two transcript variants, only one of them protein-coding, have been found for this gene. Another variant encoding an N-terminally truncated isoform has been reported, but the full-length nature of this variant has not been determined. [provided by RefSeq, May 2012].
Disorder MIM:	605579
Disorder Html:	{Influenza, severe, susceptibility to}, 614680 (3)

mRNA and Protein(s)

mRNA	Protein	Name
NM_021034.2	NP_066362.2	interferon-induced transmembrane protein 3
NM_021034.3	NP_066362.2	interferon-induced transmembrane protein 3

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Ifitm3	NP_079654.1
Rattus norvegicus (Norway rat)	Ifitm3	NP_001129596.1
Homo sapiens (human)	IFITM3	NP_066362.2
Pan troglodytes (chimpanzee)	IFITM3	NP_001185686.1
	LOC100430243	XP_002798409.1

Gene Ontology

The following IFITM3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the IFITM3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu23365	NM_021034.3 Latest version!	Homo sapiens interferon induced transmembrane protein 3 (IFITM3), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
View Old Accession Versions >>
OHu23365	NM_021034.2	Homo sapiens interferon induced transmembrane protein 3 (IFITM3), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

IFITM3 ( NM_021034.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_066362.2 Homo sapiens interferon induced transmembrane protein 3 (IFITM3), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu23365
Clone ID Related Accession (Same CDS sequence)	NM_021034.2 , NM_021034.3
Accession Version	NM_021034.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 402bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-31
Organism	Homo sapiens(human)
Product	interferon-induced transmembrane protein 3
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DB261103.1 and AI355192.1. This sequence is a reference standard in the RefSeqGene project. On Jun 6, 2007 this sequence version replaced NM_021034.1. Transcript Variant: This variant (1) represents the longer, protein-coding transcript. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BU533126.1, CD105165.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1966682, SAMEA1968189 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAATCACA CTGTCCAAAC CTTCTTCTCT CCTGTCAACA GTGGCCAGCC CCCCAACTAT 
GAGATGCTCA AGGAGGAGCA CGAGGTGGCT GTGCTGGGGG CGCCCCACAA CCCTGCTCCC 
CCGACGTCCA CCGTGATCCA CATCCGCAGC GAGACCTCCG TGCCCGACCA TGTCGTCTGG 
TCCCTGTTCA ACACCCTCTT CATGAACCCC TGCTGCCTGG GCTTCATAGC ATTCGCCTAC 
TCCGTGAAGT CTAGGGACAG GAAGATGGTT GGCGACGTGA CCGGGGCCCA GGCCTATGCC 
TCCACCGCCA AGTGCCTGAA CATCTGGGCC CTGATTCTGG GCATCCTCAT GACCATTCTG 
CTCATCGTCA TCCCAGTGCT GATCTTCCAG GCCTATGGAT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_066362.2
CDS	102..503
Translation	MNHTVQTFFSPVNSGQPPNYEMLKEEHEVAVLGAPHNPAPPTSTVIHIRSETSVPDHVVWSLFNTLFMNPCCLGFIAFAYSVKSRDRKMVGDVTGAQAYASTAKCLNIWALILGILMTILLIVIPVLIFQAYG

Target ORF information:

RefSeq Version	NM_021034.2
Organism	Homo sapiens(human)
Definition	Homo sapiens interferon induced transmembrane protein 3 (IFITM3), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_021034.2

ORF Insert Sequence:

ATGAATCACA CTGTCCAAAC CTTCTTCTCT CCTGTCAACA GTGGCCAGCC CCCCAACTAT 
GAGATGCTCA AGGAGGAGCA CGAGGTGGCT GTGCTGGGGG CGCCCCACAA CCCTGCTCCC 
CCGACGTCCA CCGTGATCCA CATCCGCAGC GAGACCTCCG TGCCCGACCA TGTCGTCTGG 
TCCCTGTTCA ACACCCTCTT CATGAACCCC TGCTGCCTGG GCTTCATAGC ATTCGCCTAC 
TCCGTGAAGT CTAGGGACAG GAAGATGGTT GGCGACGTGA CCGGGGCCCA GGCCTATGCC 
TCCACCGCCA AGTGCCTGAA CATCTGGGCC CTGATTCTGG GCATCCTCAT GACCATTCTG 
CTCATCGTCA TCCCAGTGCT GATCTTCCAG GCCTATGGAT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

IFITM3 ( NM_021034.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_066362.2 Homo sapiens interferon induced transmembrane protein 3 (IFITM3), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu23365
Clone ID Related Accession (Same CDS sequence)	NM_021034.2 , NM_021034.3
Accession Version	NM_021034.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 402bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-30
Organism	Homo sapiens(human)
Product	interferon-induced transmembrane protein 3
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DB261103.1 and AI355192.1. This sequence is a reference standard in the RefSeqGene project. On Nov 22, 2018 this sequence version replaced NM_021034.2. Transcript Variant: This variant (1) represents the longer, protein-coding transcript. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: CB150526.1, BC022439.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1966682, SAMEA1968189 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000399808.5/ ENSP00000382707.4 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGAATCACA CTGTCCAAAC CTTCTTCTCT CCTGTCAACA GTGGCCAGCC CCCCAACTAT 
GAGATGCTCA AGGAGGAGCA CGAGGTGGCT GTGCTGGGGG CGCCCCACAA CCCTGCTCCC 
CCGACGTCCA CCGTGATCCA CATCCGCAGC GAGACCTCCG TGCCCGACCA TGTCGTCTGG 
TCCCTGTTCA ACACCCTCTT CATGAACCCC TGCTGCCTGG GCTTCATAGC ATTCGCCTAC 
TCCGTGAAGT CTAGGGACAG GAAGATGGTT GGCGACGTGA CCGGGGCCCA GGCCTATGCC 
TCCACCGCCA AGTGCCTGAA CATCTGGGCC CTGATTCTGG GCATCCTCAT GACCATTCTG 
CTCATCGTCA TCCCAGTGCT GATCTTCCAG GCCTATGGAT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_066362.2
CDS	48..449
Translation	MNHTVQTFFSPVNSGQPPNYEMLKEEHEVAVLGAPHNPAPPTSTVIHIRSETSVPDHVVWSLFNTLFMNPCCLGFIAFAYSVKSRDRKMVGDVTGAQAYASTAKCLNIWALILGILMTILLIVIPVLIFQAYG

Target ORF information:

RefSeq Version	NM_021034.3
Organism	Homo sapiens(human)
Definition	Homo sapiens interferon induced transmembrane protein 3 (IFITM3), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_021034.3

ORF Insert Sequence:

ATGAATCACA CTGTCCAAAC CTTCTTCTCT CCTGTCAACA GTGGCCAGCC CCCCAACTAT 
GAGATGCTCA AGGAGGAGCA CGAGGTGGCT GTGCTGGGGG CGCCCCACAA CCCTGCTCCC 
CCGACGTCCA CCGTGATCCA CATCCGCAGC GAGACCTCCG TGCCCGACCA TGTCGTCTGG 
TCCCTGTTCA ACACCCTCTT CATGAACCCC TGCTGCCTGG GCTTCATAGC ATTCGCCTAC 
TCCGTGAAGT CTAGGGACAG GAAGATGGTT GGCGACGTGA CCGGGGCCCA GGCCTATGCC 
TCCACCGCCA AGTGCCTGAA CATCTGGGCC CTGATTCTGG GCATCCTCAT GACCATTCTG 
CTCATCGTCA TCCCAGTGCT GATCTTCCAG GCCTATGGAT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.