RIDA cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	RIDA
Entrez Gene ID	10247
Full Name	reactive intermediate imine deaminase A homolog
Synonyms	HRSP12,P14.5,PSP,UK114,hp14.5
General protein information	Preferred Names reactive intermediate imine deaminase A homolog Names 2-iminobutanoate/2-iminopropanoate deaminase 14.5 kDa translational inhibitor protein UK114 antigen homolog heat-responsive protein 12 perchloric acid-soluble protein ribonuclease UK114 translation inhibitor L-PSP ribonuclease translational inhibitor p14.5 translational inhibitor protein p14.5
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 8 Map Location: 8q22.2
Disorder MIM:	602487

mRNA and Protein(s)

mRNA	Protein	Name
NM_005836.3	NP_005827.1	2-iminobutanoate/2-iminopropanoate deaminase
NM_005836.2	NP_005827.1	2-iminobutanoate/2-iminopropanoate deaminase

Pathways from BioSystems

Homologies

Danio rerio (zebrafish)	hrsp12	NP_001012315.1
Saccharomyces cerevisiae (baker's yeast)	HMF1	NP_010978.3
Gallus gallus (chicken)	HRSP12	XP_001234689.3
Canis lupus familiaris (dog)	HRSP12	XP_532278.3
Mus musculus (house mouse)	Hrsp12	NP_032313.2
Arabidopsis thaliana (thale cress)	AT3G20390	NP_188674.1
	HRSP12	XP_001090682.1
Bos taurus (cattle)	HRSP12	NP_001029380.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP005327	XP_315342.3
Caenorhabditis elegans (roundworm)	CELE_C23G10.2	NP_741177.2
Xenopus tropicalis (tropical clawed frog)	hrp12	XP_004915188.1
Homo sapiens (human)	HRSP12	NP_005827.1
Pan troglodytes (chimpanzee)	HRSP12	XP_001149111.1
Rattus norvegicus (Norway rat)	Hrsp12	NP_113902.1
Drosophila melanogaster (fruit fly)	UK114	NP_001260465.1
Oryza sativa (rice)	Os07g0516200	NP_001059781.1

Gene Ontology
Bibliography

Related articles in PubMed

Insights into RNA biology from an atlas of mammalian mRNA-binding proteins.
Castello A, Fischer B, Eichelbaum K, Horos R, Beckmann BM, Strein C, Davey NE, Humphreys DT, Preiss T, Steinmetz LM, Krijgsveld J, Hentze MW
Cell149(6)1393-406(2012 Jun)

Genome-wide association study in multiple human prion diseases suggests genetic risk factors additional to PRNP.
Mead S, Uphill J, Beck J, Poulter M, Campbell T, Lowe J, Adamson G, Hummerich H, Klopp N, R?ckert IM, Wichmann HE, Azazi D, Plagnol V, Pako WH, Whitfield J, Alpers MP, Whittaker J, Balding DJ, Zerr I, Kretzschmar H, Collinge J
Human molecular genetics21(8)1897-906(2012 Apr)

Conserved YjgF protein family deaminates reactive enamine/imine intermediates of pyridoxal 5'-phosphate (PLP)-dependent enzyme reactions.
Lambrecht JA, Flynn JM, Downs DM
The Journal of biological chemistry287(5)3454-61(2012 Jan)

Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.
Comuzzie AG, Cole SA, Laston SL, Voruganti VS, Haack K, Gibbs RA, Butte NF
PloS one7(12)e51954(2012)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Observational study of gene-disease association. (HuGE Navigator)
Title: Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.

analysis of ligand binding sites of protein p14.5
Title: Structure-based ligand binding sites of protein p14.5, a member of protein family YER057c/YIL051c/YjgF.

x-ray crystallography study of p14.5
Title: Crystal structure of Homo sapiens protein hp14.5.

The following RIDA gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the RIDA cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu25061	NM_005836.3 Latest version!	Homo sapiens reactive intermediate imine deaminase A homolog (RIDA), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
View Old Accession Versions >>
OHu25061	NM_005836.2	Homo sapiens reactive intermediate imine deaminase A homolog (RIDA), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

RIDA ( NM_005836.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_005827.1 Homo sapiens reactive intermediate imine deaminase A homolog (RIDA), mRNA.

Price & Availability↑

CloneID	OHu25061
Clone ID Related Accession (Same CDS sequence)	NM_005836.3 , NM_005836.2
Accession Version	NM_005836.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 414bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-26
Organism	Homo sapiens(human)
Product	2-iminobutanoate/2-iminopropanoate deaminase
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from X95384.1 and BC012592.1. On Nov 23, 2018 this sequence version replaced NM_005836.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC012592.1, X95384.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1970526, SAMEA2159080 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000254878.8/ ENSP00000254878.3 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGTCGTCCT TGATCAGAAG GGTGATCAGC ACCGCGAAAG CCCCAGGGGC CATTGGACCC 
TACAGTCAAG CTGTATTAGT CGACAGGACC ATTTACATTT CAGGACAGAT AGGCATGGAC 
CCTTCAAGTG GACAGCTTGT GTCAGGAGGG GTAGCAGAAG AAGCTAAACA AGCTCTTAAA 
AACATGGGTG AAATTCTGAA AGCTGCAGGC TGTGACTTCA CTAACGTGGT GAAAACAACT 
GTTCTTCTGG CTGACATAAA TGACTTCAAT ACTGTCAATG AAATCTACAA ACAGTATTTC 
AAGAGTAATT TTCCTGCTAG AGCTGCTTAC CAAGTTGCTG CTTTACCCAA AGGCAGCCGA 
ATTGAAATTG AAGCAGTAGC TATCCAAGGA CCACTGACAA CGGCATCACT ATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_005827.1
CDS	76..489
Translation	MSSLIRRVISTAKAPGAIGPYSQAVLVDRTIYISGQIGMDPSSGQLVSGGVAEEAKQALKNMGEILKAAGCDFTNVVKTTVLLADINDFNTVNEIYKQYFKSNFPARAAYQVAALPKGSRIEIEAVAIQGPLTTASL

Target ORF information:

RefSeq Version	NM_005836.3
Organism	Homo sapiens(human)
Definition	Homo sapiens reactive intermediate imine deaminase A homolog (RIDA), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_005836.3

ORF Insert Sequence:

ATGTCGTCCT TGATCAGAAG GGTGATCAGC ACCGCGAAAG CCCCAGGGGC CATTGGACCC 
TACAGTCAAG CTGTATTAGT CGACAGGACC ATTTACATTT CAGGACAGAT AGGCATGGAC 
CCTTCAAGTG GACAGCTTGT GTCAGGAGGG GTAGCAGAAG AAGCTAAACA AGCTCTTAAA 
AACATGGGTG AAATTCTGAA AGCTGCAGGC TGTGACTTCA CTAACGTGGT GAAAACAACT 
GTTCTTCTGG CTGACATAAA TGACTTCAAT ACTGTCAATG AAATCTACAA ACAGTATTTC 
AAGAGTAATT TTCCTGCTAG AGCTGCTTAC CAAGTTGCTG CTTTACCCAA AGGCAGCCGA 
ATTGAAATTG AAGCAGTAGC TATCCAAGGA CCACTGACAA CGGCATCACT ATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RIDA ( NM_005836.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_005827.1 Homo sapiens reactive intermediate imine deaminase A homolog (RIDA), mRNA.

Price & Availability↑

CloneID	OHu25061
Clone ID Related Accession (Same CDS sequence)	NM_005836.3 , NM_005836.2
Accession Version	NM_005836.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 414bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-09-30
Organism	Homo sapiens(human)
Product	2-iminobutanoate/2-iminopropanoate deaminase
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BC012592.1, X95384.1, D62115.1 and BX348173.2. On Dec 16, 2004 this sequence version replaced NM_005836.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: X95384.1, BC012592.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1970526, SAMEA2159080 [ECO:0000348] ##Evidence-Data-END##

ATGTCGTCCT TGATCAGAAG GGTGATCAGC ACCGCGAAAG CCCCAGGGGC CATTGGACCC 
TACAGTCAAG CTGTATTAGT CGACAGGACC ATTTACATTT CAGGACAGAT AGGCATGGAC 
CCTTCAAGTG GACAGCTTGT GTCAGGAGGG GTAGCAGAAG AAGCTAAACA AGCTCTTAAA 
AACATGGGTG AAATTCTGAA AGCTGCAGGC TGTGACTTCA CTAACGTGGT GAAAACAACT 
GTTCTTCTGG CTGACATAAA TGACTTCAAT ACTGTCAATG AAATCTACAA ACAGTATTTC 
AAGAGTAATT TTCCTGCTAG AGCTGCTTAC CAAGTTGCTG CTTTACCCAA AGGCAGCCGA 
ATTGAAATTG AAGCAGTAGC TATCCAAGGA CCACTGACAA CGGCATCACT ATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_005827.1
CDS	95..508
Translation	MSSLIRRVISTAKAPGAIGPYSQAVLVDRTIYISGQIGMDPSSGQLVSGGVAEEAKQALKNMGEILKAAGCDFTNVVKTTVLLADINDFNTVNEIYKQYFKSNFPARAAYQVAALPKGSRIEIEAVAIQGPLTTASL

Target ORF information:

RefSeq Version	NM_005836.2
Organism	Homo sapiens(human)
Definition	Homo sapiens reactive intermediate imine deaminase A homolog (RIDA), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_005836.2

ORF Insert Sequence:

ATGTCGTCCT TGATCAGAAG GGTGATCAGC ACCGCGAAAG CCCCAGGGGC CATTGGACCC 
TACAGTCAAG CTGTATTAGT CGACAGGACC ATTTACATTT CAGGACAGAT AGGCATGGAC 
CCTTCAAGTG GACAGCTTGT GTCAGGAGGG GTAGCAGAAG AAGCTAAACA AGCTCTTAAA 
AACATGGGTG AAATTCTGAA AGCTGCAGGC TGTGACTTCA CTAACGTGGT GAAAACAACT 
GTTCTTCTGG CTGACATAAA TGACTTCAAT ACTGTCAATG AAATCTACAA ACAGTATTTC 
AAGAGTAATT TTCCTGCTAG AGCTGCTTAC CAAGTTGCTG CTTTACCCAA AGGCAGCCGA 
ATTGAAATTG AAGCAGTAGC TATCCAAGGA CCACTGACAA CGGCATCACT ATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Insights into RNA biology from an atlas of mammalian mRNA-binding proteins.
Cell149(6)1393-406(2012 Jun)
Castello A,Fischer B,Eichelbaum K,Horos R,Beckmann BM,Strein C,Davey NE,Humphreys DT,Preiss T,Steinmetz LM,Krijgsveld J,Hentze MW

Genome-wide association study in multiple human prion diseases suggests genetic risk factors additional to PRNP.
Human molecular genetics21(8)1897-906(2012 Apr)
Mead S,Uphill J,Beck J,Poulter M,Campbell T,Lowe J,Adamson G,Hummerich H,Klopp N,R?ckert IM,Wichmann HE,Azazi D,Plagnol V,Pako WH,Whitfield J,Alpers MP,Whittaker J,Balding DJ,Zerr I,Kretzschmar H,Collinge J

Conserved YjgF protein family deaminates reactive enamine/imine intermediates of pyridoxal 5'-phosphate (PLP)-dependent enzyme reactions.
The Journal of biological chemistry287(5)3454-61(2012 Jan)
Lambrecht JA,Flynn JM,Downs DM

Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.
PloS one7(12)e51954(2012)
Comuzzie AG,Cole SA,Laston SL,Voruganti VS,Haack K,Gibbs RA,Butte NF