CCR7 cDNA ORF clone, Gallus gallus(chicken)

Gene
Clones
gRNAs

Summary

Gene Symbol	CCR7
Entrez Gene ID	428315
Full Name	C-C motif chemokine receptor 7
General protein information	Preferred Names C-C motif chemokine receptor 7 Names C-C chemokine receptor type 7 chemokine (C-C motif) receptor 7
Gene Type	protein-coding
Organism	Gallus gallus(chicken)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001198752.1	NP_001185681.1	C-C chemokine receptor type 7 precursor

Pathways from BioSystems

Homologies

Bos taurus (cattle)	CCR7	NP_001020101.2
Danio rerio (zebrafish)	ccr7	NP_001092213.1
Pan troglodytes (chimpanzee)	CCR7	XP_511477.3
	CCR7	NP_001028056.1
Canis lupus familiaris (dog)	CCR7	XP_548131.2
Xenopus tropicalis (tropical clawed frog)	ccr7	XP_004918750.1
Homo sapiens (human)	CCR7	NP_001829.1
Mus musculus (house mouse)	Ccr7	NP_031745.2
Rattus norvegicus (Norway rat)	Ccr7	NP_955783.1
Gallus gallus (chicken)	CCR7	NP_001185681.1

Gene Ontology
Bibliography

Related articles in PubMed

Chicken interleukin-21 is costimulatory for T cells and blocks maturation of dendritic cells.
Rothwell L, Hu T, Wu Z, Kaiser P
Developmental and comparative immunology36(2)475-82(2012 Feb)

Chicken CCR6 and CCR7 are markers for immature and mature dendritic cells respectively.
Wu Z, Hu T, Kaiser P
Developmental and comparative immunology35(5)563-7(2011 May)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

After dendritic cells(DC) maturation expression levels of chCCR6 mRNA were down-regulated, whereas those of chCCR7 were up-regulated, suggesting that these two chemokine receptors play a similar role in the trafficking of chicken DC as they do in mammals.
Title: Chicken CCR6 and CCR7 are markers for immature and mature dendritic cells respectively.

The following CCR7 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CCR7 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OGa25780	NM_001198752.1 Latest version!	Gallus gallus C-C motif chemokine receptor 7 (CCR7), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$258.30 $369.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

CCR7 ( NM_001198752.1 ) cDNA ORF clone, Gallus gallus(chicken) -> NP_001185681.1 Gallus gallus C-C motif chemokine receptor 7 (CCR7), mRNA.

Price & Availability↑

CloneID	OGa25780
Clone ID Related Accession (Same CDS sequence)	NM_001198752.1
Accession Version	NM_001198752.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1125bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-06-25
Organism	Gallus gallus(chicken)
Product	C-C chemokine receptor type 7 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from HQ269806.1 and AADN05000735.1. On Nov 11, 2010 this sequence version replaced XM_425875.2. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript from the same strain was available for the full length of the gene. The extent of this transcript is supported by transcript alignments and orthologous data. ##Evidence-Data-START## Transcript exon combination :: HQ269806.1, ERR2365565.47060.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2201357, SAMEA2201362 [ECO:0000348] ##Evidence-Data-END##

ATGGACGGCG GTAAACAGCT GAGGGTCACC ATTGCTTTCA GCCTTCCTCT CATTTTTCAG 
TTCTGTGCTG GGAACAACGT CACCGACGAC TATGACGCCA ACACCACCAT TGACTACAAC 
ATGTTTGAGA TGATGTGTGA GAAGAAGGAG GTCCGTGATT TCCGTGCTGC CTTCCTCCCA 
GCCATGTACT CCCTCATCTG CTTCACAGGG CTGCTGGGAA ATGGGCTGGT GATGCTCACC 
TACATCTACT TCAAGCGGCT GAAGACCATG ACAGACATCT ACTTGCTGAA CCTGGCCCTG 
GCAGACATCC TGTTCCTGCT GACCCTCCCA TTTTGGGCCA CAAGTGCAGC CACGTTCTGG 
TGTTTTGGAG AATTTGCCTG CAAAGCAGTC TACTGCATCT GCAAAATGAG CTTCTTCAGC 
GGGATGCTGC TCCTGCTGTC CATCAGCATC GACAGGTACT TTGCCATCGT TCAGGCTGCC 
TCGGCCCACC GCTTCCGTCC CCGAATGATA TTCATTAGCA AAGTCACGTG CATCCTCATT 
TGGCTCCTGG CCTTCGTTCT CTCCATCCCC GAGCTGGTTC ACAGTGGTGT AAATAACTAT 
GACAGCCATC CCCGGTGCTC CATCATTGCC AGTGACTTGC AGACTTTCAG CACTGGCATC 
AAAGTGTCCC AGATGGTTTT TGGCTTCTTA GTTCCCCTGG TGGTCATGTC TGTCTGCTAC 
CTCATCATTA TCAAAACGTT ACTCCAGGCC CGAAACTTTG AGAAGAATAA AGCCATCAAG 
GTGATCATTG CGGTGGTCAT CGTCTTCGTC GTCTTCCAGC TGCCCTACAA CGGTGTCATG 
CTGGCCAAGA CCATCTCAGT CTTCAACAAC ACCAGCTCAT GCGACGAGAG CAAGAAGCTG 
GACATGGCAG ACGATGTGAC CTACACTCTA GCCTGCTTCC GATGCTGCCT CAATCCCTTC 
CTCTATGCCT TCATAGGCGT CAAATTCCGC AACGACCTCT TCAAGCTCTT GAAGGAGCTG 
GGCTGCCTGA GCCAGCAGCG CCTCTGGCAG CTGTCCTCCT GCCGGGAGAG CAAGAGGTTT 
TCCTTTGCCA TGGAGACAGA GACAACTACC ACCTTCTCCC CATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001185681.1
CDS	71..1195
Translation	MDGGKQLRVTIAFSLPLIFQFCAGNNVTDDYDANTTIDYNMFEMMCEKKEVRDFRAAFLPAMYSLICFTGLLGNGLVMLTYIYFKRLKTMTDIYLLNLALADILFLLTLPFWATSAATFWCFGEFACKAVYCICKMSFFSGMLLLLSISIDRYFAIVQAASAHRFRPRMIFISKVTCILIWLLAFVLSIPELVHSGVNNYDSHPRCSIIASDLQTFSTGIKVSQMVFGFLVPLVVMSVCYLIIIKTLLQARNFEKNKAIKVIIAVVIVFVVFQLPYNGVMLAKTISVFNNTSSCDESKKLDMADDVTYTLACFRCCLNPFLYAFIGVKFRNDLFKLLKELGCLSQQRLWQLSSCRESKRFSFAMETETTTTFSP

Target ORF information:

RefSeq Version	NM_001198752.1
Organism	Gallus gallus(chicken)
Definition	Gallus gallus C-C motif chemokine receptor 7 (CCR7), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001198752.1

ORF Insert Sequence:

ATGGACGGCG GTAAACAGCT GAGGGTCACC ATTGCTTTCA GCCTTCCTCT CATTTTTCAG 
TTCTGTGCTG GGAACAACGT CACCGACGAC TATGACGCCA ACACCACCAT TGACTACAAC 
ATGTTTGAGA TGATGTGTGA GAAGAAGGAG GTCCGTGATT TCCGTGCTGC CTTCCTCCCA 
GCCATGTACT CCCTCATCTG CTTCACAGGG CTGCTGGGAA ATGGGCTGGT GATGCTCACC 
TACATCTACT TCAAGCGGCT GAAGACCATG ACAGACATCT ACTTGCTGAA CCTGGCCCTG 
GCAGACATCC TGTTCCTGCT GACCCTCCCA TTTTGGGCCA CAAGTGCAGC CACGTTCTGG 
TGTTTTGGAG AATTTGCCTG CAAAGCAGTC TACTGCATCT GCAAAATGAG CTTCTTCAGC 
GGGATGCTGC TCCTGCTGTC CATCAGCATC GACAGGTACT TTGCCATCGT TCAGGCTGCC 
TCGGCCCACC GCTTCCGTCC CCGAATGATA TTCATTAGCA AAGTCACGTG CATCCTCATT 
TGGCTCCTGG CCTTCGTTCT CTCCATCCCC GAGCTGGTTC ACAGTGGTGT AAATAACTAT 
GACAGCCATC CCCGGTGCTC CATCATTGCC AGTGACTTGC AGACTTTCAG CACTGGCATC 
AAAGTGTCCC AGATGGTTTT TGGCTTCTTA GTTCCCCTGG TGGTCATGTC TGTCTGCTAC 
CTCATCATTA TCAAAACGTT ACTCCAGGCC CGAAACTTTG AGAAGAATAA AGCCATCAAG 
GTGATCATTG CGGTGGTCAT CGTCTTCGTC GTCTTCCAGC TGCCCTACAA CGGTGTCATG 
CTGGCCAAGA CCATCTCAGT CTTCAACAAC ACCAGCTCAT GCGACGAGAG CAAGAAGCTG 
GACATGGCAG ACGATGTGAC CTACACTCTA GCCTGCTTCC GATGCTGCCT CAATCCCTTC 
CTCTATGCCT TCATAGGCGT CAAATTCCGC AACGACCTCT TCAAGCTCTT GAAGGAGCTG 
GGCTGCCTGA GCCAGCAGCG CCTCTGGCAG CTGTCCTCCT GCCGGGAGAG CAAGAGGTTT 
TCCTTTGCCA TGGAGACAGA GACAACTACC ACCTTCTCCC CATGA