CYP3A5 cDNA ORF clone, Gallus gallus(chicken)

Gene
Clones
gRNAs

Summary

Gene Symbol	CYP3A5
Entrez Gene ID	414832
Full Name	cytochrome P450 family 3 subfamily A member 5
Synonyms	CYP3A37,CYP3A7
General protein information	Preferred Names cytochrome P450 family 3 subfamily A member 5 Names cytochrome P450 family 3 subfamily A member 5 cytochrome P450 A 37 cytochrome P450 CYP3A37
Gene Type	protein-coding
Organism	Gallus gallus(chicken)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001001751.2	NP_001001751.1	cytochrome P450 family 3 subfamily A member 5

Pathways from BioSystems

Homologies

Rattus norvegicus (Norway rat)	Cyp3a9	NP_671739.2
Xenopus tropicalis (tropical clawed frog)	cyp3a4	NP_001015786.1
Xenopus tropicalis (tropical clawed frog)	LOC100494419	XP_002943949.2
Gallus gallus (chicken)	CYP3A7	NP_001001751.1
Danio rerio (zebrafish)	cyp3a65	NP_001032515.1
Homo sapiens (human)	CYP3A7	NP_000756.2
Pan troglodytes (chimpanzee)	LOC100608616	XP_003318674.1
Mus musculus (house mouse)	Cyp3a13	NP_031845.1
Xenopus tropicalis (tropical clawed frog)	LOC100487665	XP_002933962.1
Oryza sativa (rice)	Os02g0221900	NP_001046325.1

Gene Ontology
Bibliography

Related articles in PubMed

E. coli infection modulates the pharmacokinetics of oral enrofloxacin by targeting P-glycoprotein in small intestine and CYP450 3A in liver and kidney of broilers.
Guo M, Sun Y, Zhang Y, Bughio S, Dai X, Ren W, Wang L
PloS one9(1)e87781(2014)

Hepatic and intestinal CYP3A expression and activity in broilers.
Osselaere A, De Bock L, Eeckhaut V, De Backer P, Van Bocxlaer J, Boussery K, Croubels S
Journal of veterinary pharmacology and therapeutics36(6)588-93(2013 Dec)

NUBIScan, an in silico approach for prediction of nuclear receptor response elements.
Podvinec M, Kaufmann MR, Handschin C, Meyer UA
Molecular endocrinology (Baltimore, Md.)16(6)1269-79(2002 Jun)

Cloning and functional expression of a first inducible avian cytochrome P450 of the CYP3A subfamily (CYP3A37).
Ourlin JC, Baader M, Fraser D, Halpert JR, Meyer UA
Archives of biochemistry and biophysics373(2)375-84(2000 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

E. coli infection modulates the pharmacokinetics of oral enrofloxacin by targeting P-glycoprotein in small intestine and CYP450 3A in liver and kidney of broilers.
Title: E. coli infection modulates the pharmacokinetics of oral enrofloxacin by targeting P-glycoprotein in small intestine and CYP450 3A in liver and kidney of broilers.

CYP3A activity revealed to be the highest in the duodenum with a decreasing trend towards the ileum. Activity in liver was comparable to duodenal activity.
Title: Hepatic and intestinal CYP3A expression and activity in broilers.

The following CYP3A5 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CYP3A5 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OGa26260	NM_001001751.2 Latest version!	Gallus gallus cytochrome P450 family 3 subfamily A member 5 (CYP3A5), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$342.30 $489.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

CYP3A5 ( NM_001001751.2 ) cDNA ORF clone, Gallus gallus(chicken) -> NP_001001751.1 Gallus gallus cytochrome P450 family 3 subfamily A member 5 (CYP3A5), mRNA.

Price & Availability↑

CloneID	OGa26260
Clone ID Related Accession (Same CDS sequence)	NM_001001751.2
Accession Version	NM_001001751.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1527bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-05-20
Organism	Gallus gallus(chicken)
Product	cytochrome P450 family 3 subfamily A member 5
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AJ250337.1. On Aug 31, 2012 this sequence version replaced NM_001001751.1. ##Evidence-Data-START## Transcript exon combination :: AJ250337.1 [ECO:0000332] ##Evidence-Data-END##

ATGAACTTTC TTCCTTTCTT CTCCATTGAA ACCTGGATCA TCTTGCTTAT TTTTGTAGTC 
CTCCTGATAA TATACGGAAC ATGGCCATTT GGGTTGTTCA AGAAGCTGGG CATTCCTGGG 
CCAAGACCAT TGCCTTTCTT TGGGACATGC CTGGAATACC GCAAAGGCTT CTTGGATTTT 
GACACTGAGT GCTTCCAGAA GTATGGGAAA ATCTGGGGGA TTTACGATGG CAGGCAGCCT 
GCGGTTGTTG TCATGGACCC CCAGATCATC AAAACCGTGC TGGTGAAAGA GTGCTACTCC 
ACCTTCACCA ACCGCAGGCG CACGGATCTA GCAGGGGTAC TGAGAAACGC TGTCTCATTA 
GCTGAAGATG ATCAGTGGAA AAGGCTCCGC ACTGTGCTCT CTCCAACCTT CACCAGTGGG 
AAGCTAAAGG AGATGTTTCC TACAATGAAG TACTTTGGGG AAATGTTGGT GAAAAATATT 
CAAAAAAGAG TGGAAAAGAA CAGCTCTGTC CCTGTGAAGG ACTTCTTTGG AAGCTACAGC 
ATGGACGTAG TCACAAGCAC TTCCTTCGGT GTGAACATCG ACTCCATGAA CAACCCCAAA 
AGCCCCTTTG TCAGAGAGAT GCAGAAGCTG ACCAAGTTTG ACTTCTTTGA TCCAGTCTTC 
ATCTTGTCAT TTGTATGTCC ATTCCTCACT CCTCTTATGG CCAAGATGAA CATCAGCTTT 
TTCCCCAGTG ATGCTGTAGA TTTCTTCATG AGGTCTATTG ACAAAATCAA GAAGGATCGT 
GAAAGGGAGA CTCACACGGG CAGAGTAGAT TTCCTGCAGA TGATGATCGA ATCCCAGAAA 
TCAGACAGCA ATGGGAGCAG CGATGCGAAG CACTCGTATA AAGCCTTGAG TGACATAGAG 
GTCCTGTCAC AAGCATTCAT CTTCATTTTT GCTGGGTATG AGCCCACCAG TAACACACTT 
GGTTACCTGG CTTACCAGCT GGCCTTGCAT CCTGATGTAC AGCAGAAGGT GGTGAATGAA 
ATAGATACCA TACTACCCAA TAAGGCTCCG CTCACGTATG AAGCGATAAT GCAGTTGGAA 
TACCTCGACA TGGCCGTGAA TGAAACCCTC CGGCTCTATC CTCTCGGAGG ACGGCTTGAG 
AGAACCTGCA AGAGAGATGT GGAAATAAAC GGGGTGACCA TTCCAAAAGG AACAATTGTT 
ATCATCCCAC CTTACACCCT GCACCGCAGC CCCGAGTACT GGCCAAACCC AGAAGAGTTC 
AGACCAGAAA GGTTCAGTAA GGAAAATAAA GACAACATAG ACCCATACAC ATACCTACCT 
TTTGGAGCTG GTCCCAGGAA CTGCATTGGG ATGCGATTTG CTCTCCTGAC TCTGAAAGTT 
GCCATCACTG CTGTATTGCA GCACTTCACC TTCCAGGTCT GCAAAGAAAC CCAGATCCCT 
CTCAAGCTGC AGTCGCTGGG ACTCACGACC CCAGAGAAGC CCATTGTTCT CAAGCTAGTC 
CCTCGGACCA ACACTGCCAA GGCATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001001751.1
CDS	47..1573
Translation	MNFLPFFSIETWIILLIFVVLLIIYGTWPFGLFKKLGIPGPRPLPFFGTCLEYRKGFLDFDTECFQKYGKIWGIYDGRQPAVVVMDPQIIKTVLVKECYSTFTNRRRTDLAGVLRNAVSLAEDDQWKRLRTVLSPTFTSGKLKEMFPTMKYFGEMLVKNIQKRVEKNSSVPVKDFFGSYSMDVVTSTSFGVNIDSMNNPKSPFVREMQKLTKFDFFDPVFILSFVCPFLTPLMAKMNISFFPSDAVDFFMRSIDKIKKDRERETHTGRVDFLQMMIESQKSDSNGSSDAKHSYKALSDIEVLSQAFIFIFAGYEPTSNTLGYLAYQLALHPDVQQKVVNEIDTILPNKAPLTYEAIMQLEYLDMAVNETLRLYPLGGRLERTCKRDVEINGVTIPKGTIVIIPPYTLHRSPEYWPNPEEFRPERFSKENKDNIDPYTYLPFGAGPRNCIGMRFALLTLKVAITAVLQHFTFQVCKETQIPLKLQSLGLTTPEKPIVLKLVPRTNTAKA

Target ORF information:

RefSeq Version	NM_001001751.2
Organism	Gallus gallus(chicken)
Definition	Gallus gallus cytochrome P450 family 3 subfamily A member 5 (CYP3A5), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001001751.2

ORF Insert Sequence:

ATGAACTTTC TTCCTTTCTT CTCCATTGAA ACCTGGATCA TCTTGCTTAT TTTTGTAGTC 
CTCCTGATAA TATACGGAAC ATGGCCATTT GGGTTGTTCA AGAAGCTGGG CATTCCTGGG 
CCAAGACCAT TGCCTTTCTT TGGGACATGC CTGGAATACC GCAAAGGCTT CTTGGATTTT 
GACACTGAGT GCTTCCAGAA GTATGGGAAA ATCTGGGGGA TTTACGATGG CAGGCAGCCT 
GCGGTTGTTG TCATGGACCC CCAGATCATC AAAACCGTGC TGGTGAAAGA GTGCTACTCC 
ACCTTCACCA ACCGCAGGCG CACGGATCTA GCAGGGGTAC TGAGAAACGC TGTCTCATTA 
GCTGAAGATG ATCAGTGGAA AAGGCTCCGC ACTGTGCTCT CTCCAACCTT CACCAGTGGG 
AAGCTAAAGG AGATGTTTCC TACAATGAAG TACTTTGGGG AAATGTTGGT GAAAAATATT 
CAAAAAAGAG TGGAAAAGAA CAGCTCTGTC CCTGTGAAGG ACTTCTTTGG AAGCTACAGC 
ATGGACGTAG TCACAAGCAC TTCCTTCGGT GTGAACATCG ACTCCATGAA CAACCCCAAA 
AGCCCCTTTG TCAGAGAGAT GCAGAAGCTG ACCAAGTTTG ACTTCTTTGA TCCAGTCTTC 
ATCTTGTCAT TTGTATGTCC ATTCCTCACT CCTCTTATGG CCAAGATGAA CATCAGCTTT 
TTCCCCAGTG ATGCTGTAGA TTTCTTCATG AGGTCTATTG ACAAAATCAA GAAGGATCGT 
GAAAGGGAGA CTCACACGGG CAGAGTAGAT TTCCTGCAGA TGATGATCGA ATCCCAGAAA 
TCAGACAGCA ATGGGAGCAG CGATGCGAAG CACTCGTATA AAGCCTTGAG TGACATAGAG 
GTCCTGTCAC AAGCATTCAT CTTCATTTTT GCTGGGTATG AGCCCACCAG TAACACACTT 
GGTTACCTGG CTTACCAGCT GGCCTTGCAT CCTGATGTAC AGCAGAAGGT GGTGAATGAA 
ATAGATACCA TACTACCCAA TAAGGCTCCG CTCACGTATG AAGCGATAAT GCAGTTGGAA 
TACCTCGACA TGGCCGTGAA TGAAACCCTC CGGCTCTATC CTCTCGGAGG ACGGCTTGAG 
AGAACCTGCA AGAGAGATGT GGAAATAAAC GGGGTGACCA TTCCAAAAGG AACAATTGTT 
ATCATCCCAC CTTACACCCT GCACCGCAGC CCCGAGTACT GGCCAAACCC AGAAGAGTTC 
AGACCAGAAA GGTTCAGTAA GGAAAATAAA GACAACATAG ACCCATACAC ATACCTACCT 
TTTGGAGCTG GTCCCAGGAA CTGCATTGGG ATGCGATTTG CTCTCCTGAC TCTGAAAGTT 
GCCATCACTG CTGTATTGCA GCACTTCACC TTCCAGGTCT GCAAAGAAAC CCAGATCCCT 
CTCAAGCTGC AGTCGCTGGG ACTCACGACC CCAGAGAAGC CCATTGTTCT CAAGCTAGTC 
CCTCGGACCA ACACTGCCAA GGCATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

E. coli infection modulates the pharmacokinetics of oral enrofloxacin by targeting P-glycoprotein in small intestine and CYP450 3A in liver and kidney of broilers.
PloS one9(1)e87781(2014)
Guo M,Sun Y,Zhang Y,Bughio S,Dai X,Ren W,Wang L

Hepatic and intestinal CYP3A expression and activity in broilers.
Journal of veterinary pharmacology and therapeutics36(6)588-93(2013 Dec)
Osselaere A,De Bock L,Eeckhaut V,De Backer P,Van Bocxlaer J,Boussery K,Croubels S

NUBIScan, an in silico approach for prediction of nuclear receptor response elements.
Molecular endocrinology (Baltimore, Md.)16(6)1269-79(2002 Jun)
Podvinec M,Kaufmann MR,Handschin C,Meyer UA

Cloning and functional expression of a first inducible avian cytochrome P450 of the CYP3A subfamily (CYP3A37).
Archives of biochemistry and biophysics373(2)375-84(2000 Jan)
Ourlin JC,Baader M,Fraser D,Halpert JR,Meyer UA