IFNG cDNA ORF clone, Gallus gallus(chicken)

Gene
Clones
gRNAs

Summary

Gene Symbol	IFNG
Entrez Gene ID	396054
Full Name	interferon gamma
General protein information	Preferred Names interferon gamma Names interferon gamma IFN-gamma Interferon-gamma level interferon-gama
Gene Type	protein-coding
Organism	Gallus gallus(chicken)
Genome	Chromosome: 1 Map Location: 1\|1 248.1 cM

mRNA and Protein(s)

mRNA	Protein	Name
NM_205149.1	NP_990480.1	interferon gamma precursor

Pathways from BioSystems
Gene Ontology
Bibliography

Related articles in PubMed

Splenic gene expression profiling in White Leghorn layer inoculated with the Salmonella enterica serovar Enteritidis.
Wu G, Liu L, Qi Y, Sun Y, Yang N, Xu G, Zhou H, Li X
Animal genetics46(6)617-26(2015 Dec)

Effects of interferon-? knockdown on vaccine-induced immunity against Marek's disease in chickens.
Haq K, Wootton SK, Barjesteh N, Golovan S, Bendall A, Sharif S
Canadian journal of veterinary research = Revue canadienne de recherche veterinaire79(1)1-7(2015 Jan)

Both host and parasite MIF molecules bind to chicken macrophages via CD74 surface receptor.
Kim S, Cox CM, Jenkins MC, Fetterer RH, Miska KB, Dalloul RA
Developmental and comparative immunology47(2)319-26(2014 Dec)

The effects of subcutaneous and intraocular administration of class B ODN CpG in chicken on the expression of TLR21, IFN-? and IL-1?.
Chrz?stek K, Wieliczko A
Polish journal of veterinary sciences17(4)593-9(2014)

Effects of zearalenone on IL-2, IL-6, and IFN-? mRNA levels in the splenic lymphocytes of chickens.
Wang YC, Deng JL, Xu SW, Peng X, Zuo ZC, Cui HM, Wang Y, Ren ZH
TheScientificWorldJournal2012567327(2012)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Knockdown of IFN-gamma did not seem to fully abrogate vaccine-induced protection against Marek's disease in chickens.
Title: Effects of interferon-? knockdown on vaccine-induced immunity against Marek's disease in chickens.

The effect of class B CpG ODN administered by subcutaneous or intraocular injection on cytokine expression in chickens is reported.
Title: The effects of subcutaneous and intraocular administration of class B ODN CpG in chicken on the expression of TLR21, IFN-? and IL-1?.

Data show that IL-10, IFN-gamma and TNF-alpha contents in the cecal tonsil were significantly decreased in the 30, 45 and 60 mg/kg groups, while IL-6 content in the cecal tonsil was only decreased in 60 mg/kg at 14 and 28 days of age.
Title: Changes of IgA+ cells and cytokines in the cecal tonsil of broilers fed on diets supplemented with vanadium.

Vitiligo in Smyth line chickens appears to be a Th1-polarized autoimmune disease, whereby IFN-gamma expression is strongly associated with parallel increases in IL-10 and IL-21, particularly during the early and active stages of vitiligo.
Title: IFN-?, IL-21, and IL-10 co-expression in evolving autoimmune vitiligo lesions of Smyth line chickens.

zearalenone affects IL-2, IL-6, and IFN-gamma mRNA levels in the splenic lymphocytes of chickens
Title: Effects of zearalenone on IL-2, IL-6, and IFN-? mRNA levels in the splenic lymphocytes of chickens.

The following IFNG gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the IFNG cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OGa26808	NM_205149.1 Latest version!	Gallus gallus interferon gamma (IFNG), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$104.30 $149.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

IFNG ( NM_205149.1 ) cDNA ORF clone, Gallus gallus(chicken) -> NP_990480.1 Gallus gallus interferon gamma (IFNG), mRNA.

Price & Availability↑

CloneID	OGa26808
Clone ID Related Accession (Same CDS sequence)	NM_205149.1
Accession Version	NM_205149.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 495bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-25
Organism	Gallus gallus(chicken)
Product	interferon gamma precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from X99774.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: X99774.1, AY705909.1 [ECO:0000332] ##Evidence-Data-END##

ATGACTTGCC AGACTTACAA CTTGTTTGTT CTGTCTGTCA TCATGATTTA TTATGGACAT 
ACTGCAAGTA GTCTAAATCT TGTTCAACTT CAAGATGATA TAGACAAACT GAAAGCTGAC 
TTTAACTCAA GTCATTCAGA TGTAGCTGAC GGTGGACCTA TTATTGTAGA GAAACTGAAG 
AACTGGACAG AGAGAAATGA GAAAAGGATC ATACTGAGCC AGATTGTTTC GATGTACTTG 
GAAATGCTTG AAAACACTGA CAAGTCAAAG CCGCACATCA AACACATATC TGAGGAGCTC 
TATACTCTGA AAAACAACCT TCCTGATGGC GTGAAGAAGG TGAAAGATAT CATGGACCTG 
GCCAAGCTCC CGATGAACGA CTTGAGAATC CAGCGCAAAG CCGCGAATGA ACTCTTCAGC 
ATCTTACAGA AGCTGGTGGA TCCTCCGAGT TTCAAAAGGA AAAGGAGCCA GTCTCAGAGG 
AGATGCAATT GCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_990480.1
CDS	106..600
Translation	MTCQTYNLFVLSVIMIYYGHTASSLNLVQLQDDIDKLKADFNSSHSDVADGGPIIVEKLKNWTERNEKRIILSQIVSMYLEMLENTDKSKPHIKHISEELYTLKNNLPDGVKKVKDIMDLAKLPMNDLRIQRKAANELFSILQKLVDPPSFKRKRSQSQRRCNC

Target ORF information:

RefSeq Version	NM_205149.1
Organism	Gallus gallus(chicken)
Definition	Gallus gallus interferon gamma (IFNG), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_205149.1

ORF Insert Sequence:

ATGACTTGCC AGACTTACAA CTTGTTTGTT CTGTCTGTCA TCATGATTTA TTATGGACAT 
ACTGCAAGTA GTCTAAATCT TGTTCAACTT CAAGATGATA TAGACAAACT GAAAGCTGAC 
TTTAACTCAA GTCATTCAGA TGTAGCTGAC GGTGGACCTA TTATTGTAGA GAAACTGAAG 
AACTGGACAG AGAGAAATGA GAAAAGGATC ATACTGAGCC AGATTGTTTC GATGTACTTG 
GAAATGCTTG AAAACACTGA CAAGTCAAAG CCGCACATCA AACACATATC TGAGGAGCTC 
TATACTCTGA AAAACAACCT TCCTGATGGC GTGAAGAAGG TGAAAGATAT CATGGACCTG 
GCCAAGCTCC CGATGAACGA CTTGAGAATC CAGCGCAAAG CCGCGAATGA ACTCTTCAGC 
ATCTTACAGA AGCTGGTGGA TCCTCCGAGT TTCAAAAGGA AAAGGAGCCA GTCTCAGAGG 
AGATGCAATT GCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Splenic gene expression profiling in White Leghorn layer inoculated with the Salmonella enterica serovar Enteritidis.
Animal genetics46(6)617-26(2015 Dec)
Wu G,Liu L,Qi Y,Sun Y,Yang N,Xu G,Zhou H,Li X

Effects of interferon-? knockdown on vaccine-induced immunity against Marek's disease in chickens.
Canadian journal of veterinary research = Revue canadienne de recherche veterinaire79(1)1-7(2015 Jan)
Haq K,Wootton SK,Barjesteh N,Golovan S,Bendall A,Sharif S

Both host and parasite MIF molecules bind to chicken macrophages via CD74 surface receptor.
Developmental and comparative immunology47(2)319-26(2014 Dec)
Kim S,Cox CM,Jenkins MC,Fetterer RH,Miska KB,Dalloul RA

The effects of subcutaneous and intraocular administration of class B ODN CpG in chicken on the expression of TLR21, IFN-? and IL-1?.
Polish journal of veterinary sciences17(4)593-9(2014)
Chrz?stek K,Wieliczko A

Effects of zearalenone on IL-2, IL-6, and IFN-? mRNA levels in the splenic lymphocytes of chickens.
TheScientificWorldJournal2012567327(2012)
Wang YC,Deng JL,Xu SW,Peng X,Zuo ZC,Cui HM,Wang Y,Ren ZH