FABP1 cDNA ORF clone, Gallus gallus(chicken)

Gene
Clones
gRNAs

Summary

Gene Symbol	FABP1
Entrez Gene ID	374015
Full Name	fatty acid binding protein 1
Synonyms	L-FABP,LFABP
General protein information	Preferred Names fatty acid binding protein 1 Names fatty acid-binding protein, liver fatty acid binding protein 1, liver fatty acid-binding protein liver fatty acid binding protein
Gene Type	protein-coding
Organism	Gallus gallus(chicken)

mRNA and Protein(s)

mRNA	Protein	Name
NM_204192.3	NP_989523.1	fatty acid-binding protein, liver

Pathways from BioSystems

Homologies

Homo sapiens (human)	FABP1	NP_001434.1
Xenopus tropicalis (tropical clawed frog)	fabp1	NP_001116883.1
Mus musculus (house mouse)	Fabp1	NP_059095.1
Gallus gallus (chicken)	FABP1	NP_989523.1
Canis lupus familiaris (dog)	FABP1	XP_005630521.1
Bos taurus (cattle)	FABP1	NP_787011.1
Danio rerio (zebrafish)	fabp1a	NP_001038177.1
Pan troglodytes (chimpanzee)	FABP1	XP_001140263.1
Rattus norvegicus (Norway rat)	Fabp1	NP_036688.1

Gene Ontology
Bibliography

Related articles in PubMed

Cold stress initiates the Nrf2/UGT1A1/L-FABP signaling pathway in chickens.
Chen XY, Li R, Geng ZY
Poultry science94(11)2597-603(2015 Nov)

Role of a liver fatty acid-binding protein gene in lipid metabolism in chicken hepatocytes.
Gao GL, Na W, Wang YX, Zhang HF, Li H, Wang QG
Genetics and molecular research : GMR14(2)4847-57(2015 May)

Differential expression of L-FABP and L-BABP between fat and lean chickens.
Zhang Q, Shi H, Liu W, Wang Y, Wang Q, Li H
Genetics and molecular research : GMR12(4)4192-206(2013 Oct)

[Whole cDNA sequence cloning and expression of chicken L-FABP gene and its relationship with lipid deposition of hybrid chickens].
Yu Y, Wang D, Sun DX, Xu GY, Li JY, Zhang Y
Yi chuan = Hereditas33(7)763-7(2011 Jul)

Characterization of critical factors influencing gene expression of two types of fatty acid-binding proteins (L-FABP and Lb-FABP) in the liver of birds.
Murai A, Furuse M, Kitaguchi K, Kusumoto K, Nakanishi Y, Kobayashi M, Horio F
Comparative biochemistry and physiology. Part A, Molecular & integrative physiology154(2)216-23(2009 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Chickens under cold stress generate anti-oxidative stress and trigger the Nrf2/ARE signaling pathway, which further up-regulates L-FABP expression to inactivate cell membrane lipid peroxidation and promote fatty acid storage against the cold environment.
Title: Cold stress initiates the Nrf2/UGT1A1/L-FABP signaling pathway in chickens.

L-FABP may affect lipid metabolism by regulating PPARalpha and L-BABP in chicken hepatocytes.
Title: Role of a liver fatty acid-binding protein gene in lipid metabolism in chicken hepatocytes.

A high expression level of L-FABP and L-BABP leads to a high lipogenesis rate and, ultimately, to lipid deposition.
Title: Differential expression of L-FABP and L-BABP between fat and lean chickens.

The L-FABP gene was over-expressed in the liver tissue and contributed to the increased lipid deposition.
Title: [Whole cDNA sequence cloning and expression of chicken L-FABP gene and its relationship with lipid deposition of hybrid chickens].

investigation of the gene expression levels of L-FABP and Lb-FABP in relation to the pre-and post-hatching development, diurnal cycle and feeding state in the liver
Title: Characterization of critical factors influencing gene expression of two types of fatty acid-binding proteins (L-FABP and Lb-FABP) in the liver of birds.

The following FABP1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the FABP1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OGa00644	NM_204192.3 Latest version!	Gallus gallus fatty acid binding protein 1 (FABP1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$104.30 $149.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

FABP1 ( NM_204192.3 ) cDNA ORF clone, Gallus gallus(chicken) -> NP_989523.1 Gallus gallus fatty acid binding protein 1 (FABP1), mRNA.

Price & Availability↑

CloneID	OGa00644
Clone ID Related Accession (Same CDS sequence)	NM_204192.3
Accession Version	NM_204192.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 384bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-05-20
Organism	Gallus gallus(chicken)
Product	fatty acid-binding protein, liver
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AF380999.1. On Feb 21, 2013 this sequence version replaced NM_204192.2. ##Evidence-Data-START## Transcript exon combination :: AF380999.1, CF249843.1 [ECO:0000332] ##Evidence-Data-END##

ATGAGCTTCA CTGGAAAGTA CGAGCTCCAG TCCCATGAAA ACTTTGAGCC TTTCATGAAA 
GCCCTCGGGC TTCCTGATGA TCAGATCCAG AAGGGTAAGG ACATCAAGAG TATCTCAGAA 
ATTGTGCAGA ATGGGAATAA GTTCAAGATC ACTGTGACTA CTGGCTCCAA AGTAATGACC 
AATGAGTTCA CCATTGGGGA AGAGTGTGAG ATGGAGCTGC TGACAGGAGA GAAGGCCAAG 
TGTATTGTTA ACATGGAAGG TAACAACAAA CTGGTTGCTA ACTTGAAGGG GCTGAAATCC 
GTGACCGAAC TCAACGGAGA CACCATCACC CATACAATGA CGAAGGGAGA CCTCACCTAC 
AAGAGAATTA GCAAGAGAAT CTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_989523.1
CDS	42..425
Translation	MSFTGKYELQSHENFEPFMKALGLPDDQIQKGKDIKSISEIVQNGNKFKITVTTGSKVMTNEFTIGEECEMELLTGEKAKCIVNMEGNNKLVANLKGLKSVTELNGDTITHTMTKGDLTYKRISKRI

Target ORF information:

RefSeq Version	NM_204192.3
Organism	Gallus gallus(chicken)
Definition	Gallus gallus fatty acid binding protein 1 (FABP1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_204192.3

ORF Insert Sequence:

ATGAGCTTCA CTGGAAAGTA CGAGCTCCAG TCCCATGAAA ACTTTGAGCC TTTCATGAAA 
GCCCTCGGGC TTCCTGATGA TCAGATCCAG AAGGGTAAGG ACATCAAGAG TATCTCAGAA 
ATTGTGCAGA ATGGGAATAA GTTCAAGATC ACTGTGACTA CTGGCTCCAA AGTAATGACC 
AATGAGTTCA CCATTGGGGA AGAGTGTGAG ATGGAGCTGC TGACAGGAGA GAAGGCCAAG 
TGTATTGTTA ACATGGAAGG TAACAACAAA CTGGTTGCTA ACTTGAAGGG GCTGAAATCC 
GTGACCGAAC TCAACGGAGA CACCATCACC CATACAATGA CGAAGGGAGA CCTCACCTAC 
AAGAGAATTA GCAAGAGAAT CTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Cold stress initiates the Nrf2/UGT1A1/L-FABP signaling pathway in chickens.
Poultry science94(11)2597-603(2015 Nov)
Chen XY,Li R,Geng ZY

Role of a liver fatty acid-binding protein gene in lipid metabolism in chicken hepatocytes.
Genetics and molecular research : GMR14(2)4847-57(2015 May)
Gao GL,Na W,Wang YX,Zhang HF,Li H,Wang QG

Differential expression of L-FABP and L-BABP between fat and lean chickens.
Genetics and molecular research : GMR12(4)4192-206(2013 Oct)
Zhang Q,Shi H,Liu W,Wang Y,Wang Q,Li H

[Whole cDNA sequence cloning and expression of chicken L-FABP gene and its relationship with lipid deposition of hybrid chickens].
Yi chuan = Hereditas33(7)763-7(2011 Jul)
Yu Y,Wang D,Sun DX,Xu GY,Li JY,Zhang Y

Characterization of critical factors influencing gene expression of two types of fatty acid-binding proteins (L-FABP and Lb-FABP) in the liver of birds.
Comparative biochemistry and physiology. Part A, Molecular & integrative physiology154(2)216-23(2009 Oct)
Murai A,Furuse M,Kitaguchi K,Kusumoto K,Nakanishi Y,Kobayashi M,Horio F