TBX22 cDNA ORF clone, Gallus gallus(chicken)

Gene
Clones
gRNAs

Summary

Gene Symbol	TBX22
Entrez Gene ID	373895
Full Name	T-box 22
General protein information	Preferred Names T-box 22 Names T-box transcription factor TBX22
Gene Type	protein-coding
Organism	Gallus gallus(chicken)

mRNA and Protein(s)

mRNA	Protein	Name
NM_204106.1	NP_989437.1	T-box transcription factor TBX22

Pathways from BioSystems

Homologies

	TBX22	XP_001102720.2
Bos taurus (cattle)	TBX22	XP_002700004.2
Mus musculus (house mouse)	Tbx22	NP_851836.2
Rattus norvegicus (Norway rat)	Tbx22	NP_001100407.1
Gallus gallus (chicken)	TBX22	NP_989437.1
Homo sapiens (human)	TBX22	NP_001103348.1
Pan troglodytes (chimpanzee)	TBX22	XP_529056.2
Xenopus tropicalis (tropical clawed frog)	tbx22	XP_002940480.2

Gene Ontology
Bibliography

Related articles in PubMed

Regulation of Tbx22 during facial and palatal development.
Fuchs A, Inthal A, Herrmann D, Cheng S, Nakatomi M, Peters H, Neub?ser A
Developmental dynamics : an official publication of the American Association of Anatomists239(11)2860-74(2010 Nov)

The function and regulation of TBX22 in avian frontonasal morphogenesis.
Higashihori N, Buchtov? M, Richman JM
Developmental dynamics : an official publication of the American Association of Anatomists239(2)458-73(2010 Feb)

Cloning and expression analysis of the chick ortholog of TBX22, the gene mutated in X-linked cleft palate and ankyloglossia.
Haenig B, Schmidt C, Kraus F, Pfordt M, Kispert A
Mechanisms of development117(1-2)321-5(2002 Sep)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Results demonstrate that FGF8 induces Tbx22 in the early face while BMP4 represses and thus restricts its expression. This regulation is conserved between chicken and mouse.
Title: Regulation of Tbx22 during facial and palatal development.

Genetic or environmental insults such as those affecting the BMP pathway could lead to a gain-of-function of TBX22 and predispose an individual to cleft lip.
Title: The function and regulation of TBX22 in avian frontonasal morphogenesis.

The following TBX22 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the TBX22 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OGa23879	NM_204106.1 Latest version!	Gallus gallus T-box 22 (TBX22), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$258.30 $369.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

TBX22 ( NM_204106.1 ) cDNA ORF clone, Gallus gallus(chicken) -> NP_989437.1 Gallus gallus T-box 22 (TBX22), mRNA.

Price & Availability↑

CloneID	OGa23879
Clone ID Related Accession (Same CDS sequence)	NM_204106.1
Accession Version	NM_204106.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1470bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-05-20
Organism	Gallus gallus(chicken)
Product	T-box transcription factor TBX22
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AF514777.1. ##Evidence-Data-START## Transcript exon combination :: AF514777.1 [ECO:0000332] ##Evidence-Data-END##

ATGGCGCTCA GCTCCCGGGC TCACGCCTTC TCGGTGGAAG CCCTCGTGGG CCGCTCGGCC 
AAGAGAAAGG GACCCGACGG CCGCGACGAG GAGAGCGGGG CGGGCTGCAG GCAGAGCCGC 
AGAGCCTCCG AGCCCGAGAA GCGGCCCAAG GCCGGCGCCG AGAGCCGGGA GGTGGGGGAC 
GAGGTGCAGG TGGAGCTGCA GGGCTCCGAG CTCTGGAAGA GGTTCCACGA GATCGGCACC 
GAGATGATCA TCACCAAGGC CGGCAGGCGG ATGTTCCCAT CGGTCAGGGT GAAGGTGAAG 
GGGCTGGAGC CACTGCAGCA GTATTACATC GCCATCGATG TTGTGCCAGT GGACTCCAAA 
CGGTACAGGT ATGTCTACCA CAGCTCACAG TGGATGGTGG CAGGGAACAC GGACCACTCC 
TGCATCACAC CACGGCTCTA CATCCACCCC GACTCCCCCT GCTCGGGGGA AACGTGGATG 
AGGCAAATCA TCAGCTTCGA CCGGGTGAAG CTCACCAACA ACGAGATGGA CGACAAGGGG 
CACATCATCC TGCAGTCCAT GCACAAGTAC AAGCCCCGTG TCCACGTTAT CGCCCAGGAC 
TCCCGCTTCG ACCTGGCGCA GATTCAGTCG CTGCCGGCTG AGGGGGTGCG CACCTTCTCC 
TTCCAGGAGA CCGAGTTCAC CACGGTCACA GCCTACCAGA ACCAGCAGAT CACCAAGCTG 
AAGATCGATA GGAACCCCTT CGCCAAAGGC TTTCGGGACC CTGGCAGGAA CAGGGGAGTG 
CTGGATGGGC TCCTGGAGCC CTTCCCATGG CGGCCACCGC TCGCTCTGGA CTTGAAGGCC 
TTTGGCGCAG ACAGCCAGGG CAGCAGCTCC AGCTCTTCCC CGGTGACCTC CAGTGCTGGG 
ACACCCTCTC CTCTCAACCC ACTGCTGTCC CCTCCGTGCT CACCTCCCAC CTTCCACCTG 
GCTGTGAGCG GTGCCAGTGC GCCGTGCCCT GAGTCCCACC TGCCCGGCCT CGGCGTGCCC 
CTCTGCTACC GGCTGTGCCC TGCCAACCTC CTCCGTCAGC AGCCCCTCAT CCTCCCCAGC 
CACCAGAAGC CAGGCGGCCC CGGTCCCCCC ATCCTGCCCC ACTTTGTGGT CGATGTACCC 
AAGCTCTCCT CCCTCGGCAT CGCCAGCCTG AAGAGCGCTA AGTCTGAAGA CCTGAGCGGG 
CCGTGTCTGC AGGTCCCCAA CTCCGCCAGC CAAATGCTGT ATGGATTACA TGCATCTGGA 
AACATTTTCC CATCGAGTCC CATTGCTCGG GAAGCACTTA ATTGTTCCCT ACATCCTCCA 
TATGGTTTGT ACGGCTACAG CTTCTCCATG CCATCCAGAC TGACGAGCAC GGCGAGCCAT 
TTCGGAGTGA GTGACAGCCT GCCCGCTGCC TTCAGGGACG GCCGATGCAA TCACCCCAGC 
TGGCACTCAG CAATTAACCA CTGCCTTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_989437.1
CDS	164..1633
Translation	MALSSRAHAFSVEALVGRSAKRKGPDGRDEESGAGCRQSRRASEPEKRPKAGAESREVGDEVQVELQGSELWKRFHEIGTEMIITKAGRRMFPSVRVKVKGLEPLQQYYIAIDVVPVDSKRYRYVYHSSQWMVAGNTDHSCITPRLYIHPDSPCSGETWMRQIISFDRVKLTNNEMDDKGHIILQSMHKYKPRVHVIAQDSRFDLAQIQSLPAEGVRTFSFQETEFTTVTAYQNQQITKLKIDRNPFAKGFRDPGRNRGVLDGLLEPFPWRPPLALDLKAFGADSQGSSSSSSPVTSSAGTPSPLNPLLSPPCSPPTFHLAVSGASAPCPESHLPGLGVPLCYRLCPANLLRQQPLILPSHQKPGGPGPPILPHFVVDVPKLSSLGIASLKSAKSEDLSGPCLQVPNSASQMLYGLHASGNIFPSSPIAREALNCSLHPPYGLYGYSFSMPSRLTSTASHFGVSDSLPAAFRDGRCNHPSWHSAINHCL

Target ORF information:

RefSeq Version	NM_204106.1
Organism	Gallus gallus(chicken)
Definition	Gallus gallus T-box 22 (TBX22), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_204106.1

ORF Insert Sequence:

ATGGCGCTCA GCTCCCGGGC TCACGCCTTC TCGGTGGAAG CCCTCGTGGG CCGCTCGGCC 
AAGAGAAAGG GACCCGACGG CCGCGACGAG GAGAGCGGGG CGGGCTGCAG GCAGAGCCGC 
AGAGCCTCCG AGCCCGAGAA GCGGCCCAAG GCCGGCGCCG AGAGCCGGGA GGTGGGGGAC 
GAGGTGCAGG TGGAGCTGCA GGGCTCCGAG CTCTGGAAGA GGTTCCACGA GATCGGCACC 
GAGATGATCA TCACCAAGGC CGGCAGGCGG ATGTTCCCAT CGGTCAGGGT GAAGGTGAAG 
GGGCTGGAGC CACTGCAGCA GTATTACATC GCCATCGATG TTGTGCCAGT GGACTCCAAA 
CGGTACAGGT ATGTCTACCA CAGCTCACAG TGGATGGTGG CAGGGAACAC GGACCACTCC 
TGCATCACAC CACGGCTCTA CATCCACCCC GACTCCCCCT GCTCGGGGGA AACGTGGATG 
AGGCAAATCA TCAGCTTCGA CCGGGTGAAG CTCACCAACA ACGAGATGGA CGACAAGGGG 
CACATCATCC TGCAGTCCAT GCACAAGTAC AAGCCCCGTG TCCACGTTAT CGCCCAGGAC 
TCCCGCTTCG ACCTGGCGCA GATTCAGTCG CTGCCGGCTG AGGGGGTGCG CACCTTCTCC 
TTCCAGGAGA CCGAGTTCAC CACGGTCACA GCCTACCAGA ACCAGCAGAT CACCAAGCTG 
AAGATCGATA GGAACCCCTT CGCCAAAGGC TTTCGGGACC CTGGCAGGAA CAGGGGAGTG 
CTGGATGGGC TCCTGGAGCC CTTCCCATGG CGGCCACCGC TCGCTCTGGA CTTGAAGGCC 
TTTGGCGCAG ACAGCCAGGG CAGCAGCTCC AGCTCTTCCC CGGTGACCTC CAGTGCTGGG 
ACACCCTCTC CTCTCAACCC ACTGCTGTCC CCTCCGTGCT CACCTCCCAC CTTCCACCTG 
GCTGTGAGCG GTGCCAGTGC GCCGTGCCCT GAGTCCCACC TGCCCGGCCT CGGCGTGCCC 
CTCTGCTACC GGCTGTGCCC TGCCAACCTC CTCCGTCAGC AGCCCCTCAT CCTCCCCAGC 
CACCAGAAGC CAGGCGGCCC CGGTCCCCCC ATCCTGCCCC ACTTTGTGGT CGATGTACCC 
AAGCTCTCCT CCCTCGGCAT CGCCAGCCTG AAGAGCGCTA AGTCTGAAGA CCTGAGCGGG 
CCGTGTCTGC AGGTCCCCAA CTCCGCCAGC CAAATGCTGT ATGGATTACA TGCATCTGGA 
AACATTTTCC CATCGAGTCC CATTGCTCGG GAAGCACTTA ATTGTTCCCT ACATCCTCCA 
TATGGTTTGT ACGGCTACAG CTTCTCCATG CCATCCAGAC TGACGAGCAC GGCGAGCCAT 
TTCGGAGTGA GTGACAGCCT GCCCGCTGCC TTCAGGGACG GCCGATGCAA TCACCCCAGC 
TGGCACTCAG CAATTAACCA CTGCCTTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Regulation of Tbx22 during facial and palatal development.
Developmental dynamics : an official publication of the American Association of Anatomists239(11)2860-74(2010 Nov)
Fuchs A,Inthal A,Herrmann D,Cheng S,Nakatomi M,Peters H,Neub?ser A

The function and regulation of TBX22 in avian frontonasal morphogenesis.
Developmental dynamics : an official publication of the American Association of Anatomists239(2)458-73(2010 Feb)
Higashihori N,Buchtov? M,Richman JM

Cloning and expression analysis of the chick ortholog of TBX22, the gene mutated in X-linked cleft palate and ankyloglossia.
Mechanisms of development117(1-2)321-5(2002 Sep)
Haenig B,Schmidt C,Kraus F,Pfordt M,Kispert A