ccr7 cDNA ORF clone, Danio rerio(zebrafish)

Gene
Clones
gRNAs

Summary

Gene Symbol	ccr7
Entrez Gene ID	565958
Full Name	chemokine (C-C motif) receptor 7
Synonyms	zgc:165629
General protein information	Preferred Names chemokine (C-C motif) receptor 7 Names C-C chemokine receptor type 7 zfCCR7
Gene Type	protein-coding
Organism	Danio rerio(zebrafish)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001098743.1	NP_001092213.1	C-C chemokine receptor type 7 precursor

Pathways from BioSystems

Homologies

Bos taurus (cattle)	CCR7	NP_001020101.2
Danio rerio (zebrafish)	ccr7	NP_001092213.1
Pan troglodytes (chimpanzee)	CCR7	XP_511477.3
	CCR7	NP_001028056.1
Canis lupus familiaris (dog)	CCR7	XP_548131.2
Xenopus tropicalis (tropical clawed frog)	ccr7	XP_004918750.1
Homo sapiens (human)	CCR7	NP_001829.1
Mus musculus (house mouse)	Ccr7	NP_031745.2
Rattus norvegicus (Norway rat)	Ccr7	NP_955783.1
Gallus gallus (chicken)	CCR7	NP_001185681.1

Gene Ontology
Bibliography

Related articles in PubMed

CXCR1 remodels the vascular niche to promote hematopoietic stem and progenitor cell engraftment.
Blaser BW, Moore JL, Hagedorn EJ, Li B, Riquelme R, Lichtig A, Yang S, Zhou Y, Tamplin OJ, Binder V, Zon LI
The Journal of experimental medicine214(4)1011-1027(2017 Apr)

Vitamin K reduces hypermineralisation in zebrafish models of PXE and GACI.
Mackay EW, Apschner A, Schulte-Merker S
Development (Cambridge, England)142(6)1095-101(2015 Mar)

Systematic classification of vertebrate chemokines based on conserved synteny and evolutionary history.
Nomiyama H, Osada N, Yoshie O
Genes to cells : devoted to molecular & cellular mechanisms18(1)1-16(2013 Jan)

Chemokine GPCR signaling inhibits ?-catenin during zebrafish axis formation.
Wu SY, Shin J, Sepich DS, Solnica-Krezel L
PLoS biology10(10)e1001403(2012)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Ccr7 functions during axis formation as a GPCR to inhibit beta-catenin, likely by promoting Ca(2+) transients throughout the blastula.
Title: Chemokine GPCR signaling inhibits ?-catenin during zebrafish axis formation.

The following ccr7 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ccr7 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ODa33606	NM_001098743.1 Latest version!	Danio rerio chemokine (C-C motif) receptor 7 (ccr7), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$258.30 $369.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

ccr7 ( NM_001098743.1 ) cDNA ORF clone, Danio rerio(zebrafish) -> NP_001092213.1 Danio rerio chemokine (C-C motif) receptor 7 (ccr7), mRNA.

Price & Availability↑

CloneID	ODa33606
Clone ID Related Accession (Same CDS sequence)	NM_001098743.1
Accession Version	NM_001098743.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1119bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-09-22
Organism	Danio rerio(zebrafish)
Product	C-C chemokine receptor type 7 precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC142913.1. On Jun 20, 2007 this sequence version replaced XM_689227.2. ##Evidence-Data-START## Transcript exon combination :: BC142913.1, CK029874.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01765705 [ECO:0000348] ##Evidence-Data-END##

ATGCACGCGT ATACCGTGTT TTGTCCTGTG TTGCTGATAT GGTCTTGCCA CATAAAGAAA 
AGTTGGTCCA ACATGACTGA ACACCAAATG GGTGAAAAGG CTACAACAGA GTATGATTAT 
ACCACAGGAA CAGTAGATTA TGACATTTAT GAACAAAGTT GCAATAAGAC CAACAATCGT 
ACTTTCCGAG CCTGGTTCCT GCCCACCATC TACACCATCA TCTGCCTCCT GGCTCTCATG 
GGGAACTTTC TGGTCATCCT GACCTACCTT TACTTCAAGA GGCTGAAGAC AATGACCGAT 
GTCTACCTGT TTAATCTGGC CATGGCTGAC CTGCTGTTTG CCATTTCTCT CCCCTTCTGG 
GCAGCTAGTT TCATGAGTAC TTGGCATTTG GGTTTGTATC CATGCAAAGC CATGTTTACT 
ATCTACAAGG TCAGCTTCTT CAGCGGCATG TTCCTCCTCA CCTGCATCAG CATTGATCGC 
TATTTCTCCA TAACGAAGGC TGTTTCTGCT CATCGTTGTC GCTCCAGTGC GGTCTACTAT 
GGTCAGGTGT CTTCTCTAGT CACCTGGGTG ATAGCGATCG TCTTTTCTGT ACCTGACATG 
GTTTTTGCTG TAATCAATAG CAGGGGCACC TGTTCAGCAA ATGTCAACTA TCAGGACTAT 
TATGTTAAGA TGGTGATAAG TCAGATGGTC TTGGGATTTA TCATCCCAGC AGTCGTCATG 
GGGTTCTGTT ACATCTGCAT TATTAAAACC CTCATGCAGG CCAAGAACTT TGAGAGAAAT 
AAAGCCTTCA AGGTAATCAT TGCAGTGGTC GTTGTCTTCG TCTTCAGTCA GCTACCCTAC 
AATGTAGTCA TGGGAGTCTC TGTCCAGCAA ACAACAGATT GTGCCAAGGA CAATACTCGT 
CTTTTTGCTC TGGATGTGAC CATGGCTGTG GCCTTCTTGC GCTGCTGTGT GAACCCATTC 
CTGTACGCCT TCATTGGGGT AAAGTTTCGC AATGATCTCC TGAAGCTTTT GAAAGACCTG 
GGATGTCTCC GAACGAGCCA CTTAATGTAC ACCCACTGCG GGAGACGAAG ATCTTCTGTC 
GGCCTGGACA CAGAAACCAC CACAACCTTT TCCCCATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001092213.1
CDS	42..1160
Translation	MHAYTVFCPVLLIWSCHIKKSWSNMTEHQMGEKATTEYDYTTGTVDYDIYEQSCNKTNNRTFRAWFLPTIYTIICLLALMGNFLVILTYLYFKRLKTMTDVYLFNLAMADLLFAISLPFWAASFMSTWHLGLYPCKAMFTIYKVSFFSGMFLLTCISIDRYFSITKAVSAHRCRSSAVYYGQVSSLVTWVIAIVFSVPDMVFAVINSRGTCSANVNYQDYYVKMVISQMVLGFIIPAVVMGFCYICIIKTLMQAKNFERNKAFKVIIAVVVVFVFSQLPYNVVMGVSVQQTTDCAKDNTRLFALDVTMAVAFLRCCVNPFLYAFIGVKFRNDLLKLLKDLGCLRTSHLMYTHCGRRRSSVGLDTETTTTFSP

Target ORF information:

RefSeq Version	NM_001098743.1
Organism	Danio rerio(zebrafish)
Definition	Danio rerio chemokine (C-C motif) receptor 7 (ccr7), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001098743.1

ORF Insert Sequence:

ATGCACGCGT ATACCGTGTT TTGTCCTGTG TTGCTGATAT GGTCTTGCCA CATAAAGAAA 
AGTTGGTCCA ACATGACTGA ACACCAAATG GGTGAAAAGG CTACAACAGA GTATGATTAT 
ACCACAGGAA CAGTAGATTA TGACATTTAT GAACAAAGTT GCAATAAGAC CAACAATCGT 
ACTTTCCGAG CCTGGTTCCT GCCCACCATC TACACCATCA TCTGCCTCCT GGCTCTCATG 
GGGAACTTTC TGGTCATCCT GACCTACCTT TACTTCAAGA GGCTGAAGAC AATGACCGAT 
GTCTACCTGT TTAATCTGGC CATGGCTGAC CTGCTGTTTG CCATTTCTCT CCCCTTCTGG 
GCAGCTAGTT TCATGAGTAC TTGGCATTTG GGTTTGTATC CATGCAAAGC CATGTTTACT 
ATCTACAAGG TCAGCTTCTT CAGCGGCATG TTCCTCCTCA CCTGCATCAG CATTGATCGC 
TATTTCTCCA TAACGAAGGC TGTTTCTGCT CATCGTTGTC GCTCCAGTGC GGTCTACTAT 
GGTCAGGTGT CTTCTCTAGT CACCTGGGTG ATAGCGATCG TCTTTTCTGT ACCTGACATG 
GTTTTTGCTG TAATCAATAG CAGGGGCACC TGTTCAGCAA ATGTCAACTA TCAGGACTAT 
TATGTTAAGA TGGTGATAAG TCAGATGGTC TTGGGATTTA TCATCCCAGC AGTCGTCATG 
GGGTTCTGTT ACATCTGCAT TATTAAAACC CTCATGCAGG CCAAGAACTT TGAGAGAAAT 
AAAGCCTTCA AGGTAATCAT TGCAGTGGTC GTTGTCTTCG TCTTCAGTCA GCTACCCTAC 
AATGTAGTCA TGGGAGTCTC TGTCCAGCAA ACAACAGATT GTGCCAAGGA CAATACTCGT 
CTTTTTGCTC TGGATGTGAC CATGGCTGTG GCCTTCTTGC GCTGCTGTGT GAACCCATTC 
CTGTACGCCT TCATTGGGGT AAAGTTTCGC AATGATCTCC TGAAGCTTTT GAAAGACCTG 
GGATGTCTCC GAACGAGCCA CTTAATGTAC ACCCACTGCG GGAGACGAAG ATCTTCTGTC 
GGCCTGGACA CAGAAACCAC CACAACCTTT TCCCCATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

CXCR1 remodels the vascular niche to promote hematopoietic stem and progenitor cell engraftment.
The Journal of experimental medicine214(4)1011-1027(2017 Apr)
Blaser BW,Moore JL,Hagedorn EJ,Li B,Riquelme R,Lichtig A,Yang S,Zhou Y,Tamplin OJ,Binder V,Zon LI

Vitamin K reduces hypermineralisation in zebrafish models of PXE and GACI.
Development (Cambridge, England)142(6)1095-101(2015 Mar)
Mackay EW,Apschner A,Schulte-Merker S

Systematic classification of vertebrate chemokines based on conserved synteny and evolutionary history.
Genes to cells : devoted to molecular & cellular mechanisms18(1)1-16(2013 Jan)
Nomiyama H,Osada N,Yoshie O

Chemokine GPCR signaling inhibits ?-catenin during zebrafish axis formation.
PLoS biology10(10)e1001403(2012)
Wu SY,Shin J,Sepich DS,Solnica-Krezel L