sncgb cDNA ORF clone, Danio rerio(zebrafish)

Gene
Clones
gRNAs

Summary

Gene Symbol	sncgb
Entrez Gene ID	553679
Full Name	synuclein, gamma b (breast cancer-specific protein 1)
Synonyms	sncg,zgc:112131
General protein information	Preferred Names synuclein, gamma b (breast cancer-specific protein 1) Names synuclein, gamma b (breast cancer-specific protein 1) Sncg1 gamma1a-synuclein sncga synuclein, gamma (breast cancer-specific protein 1) zSyn-γ1 zSynA
Gene Type	protein-coding
Organism	Danio rerio(zebrafish)

mRNA and Protein(s)

mRNA	Protein	Name
XM_021480112.1	XP_021335787.1	synuclein, gamma b (breast cancer-specific protein 1) isoform X1
NM_001020652.1	NP_001018488.1	synuclein, gamma b (breast cancer-specific protein 1)

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	SNCG	XP_507891.2
	SNCG	XP_001083650.1
Bos taurus (cattle)	SNCG	NP_776611.1
Canis lupus familiaris (dog)	SNCG	XP_005619498.1
Rattus norvegicus (Norway rat)	Sncg	NP_113876.1
Homo sapiens (human)	SNCG	NP_003078.2
Mus musculus (house mouse)	Sncg	NP_035560.1
Gallus gallus (chicken)	SNCG	NP_990003.1
Danio rerio (zebrafish)	sncgb	NP_001018488.1
Danio rerio (zebrafish)	sncga	NP_001017567.1
Xenopus tropicalis (tropical clawed frog)	sncg	NP_001016102.1

Gene Ontology
Bibliography

Related articles in PubMed

Neurotoxicity of the Parkinson Disease-Associated Pesticide Ziram Is Synuclein-Dependent in Zebrafish Embryos.
Lulla A, Barnhill L, Bitan G, Ivanova MI, Nguyen B, O'Donnell K, Stahl MC, Yamashiro C, Kl?rner FG, Schrader T, Sagasti A, Bronstein JM
Environmental health perspectives124(11)1766-1775(2016 Nov)

1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine induced Parkinson's disease in zebrafish.
Sarath Babu N, Murthy ChL, Kakara S, Sharma R, Brahmendra Swamy CV, Idris MM
Proteomics16(9)1407-20(2016 05)

Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.
Pasquier J, Cabau C, Nguyen T, Jouanno E, Severac D, Braasch I, Journot L, Pontarotti P, Klopp C, Postlethwait JH, Guiguen Y, Bobe J
BMC genomics17368(2016 05)

Zinc finger protein 219-like (ZNF219L) and Sox9a regulate synuclein-?2 (sncgb) expression in the developing notochord of zebrafish.
Lien HW, Yang CH, Cheng CH, Liao YF, Han YS, Huang CJ
Biochemical and biophysical research communications442(3-4)189-94(2013 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

these results reveal that coordination of ZNF219L with Sox9a is involved in the regulation of notochord-specific expression of sncgb.
Title: Zinc finger protein 219-like (ZNF219L) and Sox9a regulate synuclein-?2 (sncgb) expression in the developing notochord of zebrafish.

Data show the sequences of zebrafish synucleins are very similar to those of the human proteins. Whole-mount in situ hybridization show that sncgb was expressed exclusively in the notochord.
Title: Discovery and characterization of three novel synuclein genes in zebrafish.

The following sncgb gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the sncgb cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ODa01574	NM_001020652.1 Latest version!	Danio rerio synuclein, gamma b (breast cancer-specific protein 1) (sncgb), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$104.30 $149.00
ODa148197	XM_021480112.1 Latest version!	Danio rerio synuclein, gamma b (breast cancer-specific protein 1) (sncgb), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$104.30 $149.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

sncgb ( NM_001020652.1 ) cDNA ORF clone, Danio rerio(zebrafish) -> NP_001018488.1 Danio rerio synuclein, gamma b (breast cancer-specific protein 1) (sncgb), mRNA.

Price & Availability↑

CloneID	ODa01574
Clone ID Related Accession (Same CDS sequence)	NM_001020652.1
Accession Version	NM_001020652.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 345bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-20
Organism	Danio rerio(zebrafish)
Product	synuclein, gamma b (breast cancer-specific protein 1)
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC095672.1. ##Evidence-Data-START## Transcript exon combination :: BC095672.1, EU368946.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END##

ATGGATGTTC TAATGAAGGG ATTCTCCATG GCCAAAGAAG GAGTGGTGGC GGCCGCTGAG 
AAGACTAAAG CTGGGGTTGA AGAGGCAGCG CTCAAGACCA AGGAAGGGGT CACGTATGTG 
GGCAACAAGA CAAAGGAGGG AATGGTTTCA GGTGTAAACA CAGTTGTCCA GAAGACCACC 
GACCAGGCAA ATATAGTGGG TGAAACGGCA GTAGGCGGTG CTAATGTAGC GGGCCAGAAT 
ACAGTAGAGG GACTGGAGAA CGTGGCGGCA TCGACCGGCA TGGTGAACCC GGGTGACTTC 
TCTCATGGTG GTATGGAAGG AGGAGAGGGT GGAGAGGGAT ATTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001018488.1
CDS	142..486
Translation	MDVLMKGFSMAKEGVVAAAEKTKAGVEEAALKTKEGVTYVGNKTKEGMVSGVNTVVQKTTDQANIVGETAVGGANVAGQNTVEGLENVAASTGMVNPGDFSHGGMEGGEGGEGY

Target ORF information:

RefSeq Version	NM_001020652.1
Organism	Danio rerio(zebrafish)
Definition	Danio rerio synuclein, gamma b (breast cancer-specific protein 1) (sncgb), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001020652.1

ORF Insert Sequence:

ATGGATGTTC TAATGAAGGG ATTCTCCATG GCCAAAGAAG GAGTGGTGGC GGCCGCTGAG 
AAGACTAAAG CTGGGGTTGA AGAGGCAGCG CTCAAGACCA AGGAAGGGGT CACGTATGTG 
GGCAACAAGA CAAAGGAGGG AATGGTTTCA GGTGTAAACA CAGTTGTCCA GAAGACCACC 
GACCAGGCAA ATATAGTGGG TGAAACGGCA GTAGGCGGTG CTAATGTAGC GGGCCAGAAT 
ACAGTAGAGG GACTGGAGAA CGTGGCGGCA TCGACCGGCA TGGTGAACCC GGGTGACTTC 
TCTCATGGTG GTATGGAAGG AGGAGAGGGT GGAGAGGGAT ATTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

sncgb ( XM_021480112.1 ) cDNA ORF clone, Danio rerio(zebrafish) -> XP_021335787.1 Danio rerio synuclein, gamma b (breast cancer-specific protein 1) (sncgb), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ODa148197
Clone ID Related Accession (Same CDS sequence)	XM_021480112.1
Accession Version	XM_021480112.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 363bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-06-14
Organism	Danio rerio(zebrafish)
Product	synuclein, gamma b (breast cancer-specific protein 1) isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_007123.7) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Danio rerio Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGATGTTC TAATGAAGGG ATTCTCCATG GCCAAAGAAG GAGTGGTGGC GGCCGCTGAG 
AAGACTAAAG CTGGGGTTGA AGAGGCAGCG CTCAAGACCA AGGAAGGGGT CATGTATGTG 
GGCAACAAGA CAAAGGAGGG AATGGTTTCA GGTGTAAACA CAGTTGTCCA GAAGACCACC 
GACCAGGCAA ATATAGTGGG TGAAACGGCA GTAGGCGGTG CTAATGTAGC GGGCCAGAAT 
ACAGTAGAGG GACTGGAGAA CGTGGCGGCA TCGACCGGCA TGGTGAACCC GGATGAGGCT 
TTATATGAGG GTGACTTCTC TCATGGTGGT ATGGAAGGAG GAGAGGGTGG AGAGGGATAT 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_021335787.1
CDS	208..570
Translation	MDVLMKGFSMAKEGVVAAAEKTKAGVEEAALKTKEGVMYVGNKTKEGMVSGVNTVVQKTTDQANIVGETAVGGANVAGQNTVEGLENVAASTGMVNPDEALYEGDFSHGGMEGGEGGEGY

Target ORF information:

RefSeq Version	XM_021480112.1
Organism	Danio rerio(zebrafish)
Definition	Danio rerio synuclein, gamma b (breast cancer-specific protein 1) (sncgb), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_021480112.1

ORF Insert Sequence:

ATGGATGTTC TAATGAAGGG ATTCTCCATG GCCAAAGAAG GAGTGGTGGC GGCCGCTGAG 
AAGACTAAAG CTGGGGTTGA AGAGGCAGCG CTCAAGACCA AGGAAGGGGT CATGTATGTG 
GGCAACAAGA CAAAGGAGGG AATGGTTTCA GGTGTAAACA CAGTTGTCCA GAAGACCACC 
GACCAGGCAA ATATAGTGGG TGAAACGGCA GTAGGCGGTG CTAATGTAGC GGGCCAGAAT 
ACAGTAGAGG GACTGGAGAA CGTGGCGGCA TCGACCGGCA TGGTGAACCC GGATGAGGCT 
TTATATGAGG GTGACTTCTC TCATGGTGGT ATGGAAGGAG GAGAGGGTGG AGAGGGATAT 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Neurotoxicity of the Parkinson Disease-Associated Pesticide Ziram Is Synuclein-Dependent in Zebrafish Embryos.
Environmental health perspectives124(11)1766-1775(2016 Nov)
Lulla A,Barnhill L,Bitan G,Ivanova MI,Nguyen B,O'Donnell K,Stahl MC,Yamashiro C,Kl?rner FG,Schrader T,Sagasti A,Bronstein JM

1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine induced Parkinson's disease in zebrafish.
Proteomics16(9)1407-20(2016 05)
Sarath Babu N,Murthy ChL,Kakara S,Sharma R,Brahmendra Swamy CV,Idris MM

Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.
BMC genomics17368(2016 05)
Pasquier J,Cabau C,Nguyen T,Jouanno E,Severac D,Braasch I,Journot L,Pontarotti P,Klopp C,Postlethwait JH,Guiguen Y,Bobe J

Zinc finger protein 219-like (ZNF219L) and Sox9a regulate synuclein-?2 (sncgb) expression in the developing notochord of zebrafish.
Biochemical and biophysical research communications442(3-4)189-94(2013 Dec)
Lien HW,Yang CH,Cheng CH,Liao YF,Han YS,Huang CJ