blvrb cDNA ORF clone, Danio rerio(zebrafish)

Gene
Clones
gRNAs

Summary

Gene Symbol	blvrb
Entrez Gene ID	436959
Full Name	biliverdin reductase B
Synonyms	CH73-262H23.3,cb1064,wu:fb73f01,zgc:91854
General protein information	Preferred Names biliverdin reductase B Names flavin reductase (NADPH) biliverdin reductase B (flavin reductase (NADPH))
Gene Type	protein-coding
Organism	Danio rerio(zebrafish)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001002686.1	NP_001002686.1	flavin reductase (NADPH)

Pathways from BioSystems

Homologies

Homo sapiens (human)	BLVRB	NP_000704.1
Pan troglodytes (chimpanzee)	BLVRB	XP_512666.3
Danio rerio (zebrafish)	blvrb	NP_001002686.1
Bos taurus (cattle)	BLVRB	NP_776676.1
Rattus norvegicus (Norway rat)	Blvrb	NP_001099706.1
Drosophila melanogaster (fruit fly)	CG9471	NP_649943.2
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP001321	XP_321824.3
Mus musculus (house mouse)	Blvrb	NP_659172.1
Xenopus tropicalis (tropical clawed frog)	blvrb	NP_001096269.1
	BLVRB	XP_001091330.1
Canis lupus familiaris (dog)	BLVRB	XP_533666.2

Gene Ontology
Bibliography

Related articles in PubMed

Evolution of complexity in the zebrafish synapse proteome.
Bay?s ?, Collins MO, Reig-Viader R, Gou G, Goulding D, Izquierdo A, Choudhary JS, Emes RD, Grant SG
Nature communications814613(2017 Mar)

Spatiotemporal expression and transcriptional regulation of heme oxygenase and biliverdin reductase genes in zebrafish (Danio rerio) suggest novel roles during early developmental periods of heightened oxidative stress.
Holowiecki A, O'Shields B, Jenny MJ
Comparative biochemistry and physiology. Toxicology & pharmacology : CBP191138-151(2017 Jan)

Characterization of heme oxygenase and biliverdin reductase gene expression in zebrafish (Danio rerio): Basal expression and response to pro-oxidant exposures.
Holowiecki A, O'Shields B, Jenny MJ
Toxicology and applied pharmacology31174-87(2016 Nov)

Proteomic profile of zebrafish brain based on two-dimensional gel electrophoresis matrix-assisted laser desorption/ionization MS/MS analysis.
Singh SK, Sundaram CS, Shanbhag S, Idris MM
Zebrafish7(2)169-77(2010 Jun)

Loss of gata1 but not gata2 converts erythropoiesis to myelopoiesis in zebrafish embryos.
Galloway JL, Wingert RA, Thisse C, Thisse B, Zon LI
Developmental cell8(1)109-16(2005 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Suggest that Gata-1 and Nrf2a play differential roles in regulating the heme degradation enzymes hmox1a/bvra/bvrb during an early developmental period of heightened cellular stress
Title: Spatiotemporal expression and transcriptional regulation of heme oxygenase and biliverdin reductase genes in zebrafish (Danio rerio) suggest novel roles during early developmental periods of heightened oxidative stress.

The following blvrb gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the blvrb cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ODa31620	NM_001002686.1 Latest version!	Danio rerio biliverdin reductase B (blvrb), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$104.30 $149.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

blvrb ( NM_001002686.1 ) cDNA ORF clone, Danio rerio(zebrafish) -> NP_001002686.1 Danio rerio biliverdin reductase B (blvrb), mRNA.

Price & Availability↑

CloneID	ODa31620
Clone ID Related Accession (Same CDS sequence)	NM_001002686.1
Accession Version	NM_001002686.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 579bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-30
Organism	Danio rerio(zebrafish)
Product	flavin reductase (NADPH)
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC076451.1. On or before Jul 6, 2005 this sequence version replaced XM_679039.1, XM_704691.1. ##Evidence-Data-START## Transcript exon combination :: BC076451.1, EH501610.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2168446, SAMEA2168447 [ECO:0000348] ##Evidence-Data-END##

ATGACGGGGT TAGCGACCTT ACCTATCGCA GTGGCCTCAG GTTACAATGT GACGGTGCTG 
GTGAGAGACC CTGCAAGGCT TCCTCCAGAT CATAAGGCCT CCAGAGTGGT TGTGGGAGAC 
GTTCTGAACA AAAACGATGT AAAGAAGACC CTGGAGGGTC AGGATGCAGT CATCATCATT 
CTAGGGACAA GGAATGATCT CAGTCCCACA ACGATGATGT CTGAGGGAAC GCGGAACATC 
GTGGAGGTCA TGAAAGCTCG TGGAATCCGC AAAGTTGTTG GATGCATGTC AGCATTCCTC 
TTGTGGGATC GATCCAAAGT TCCTCCTCGC TTGGTGCCGG TCACTGAAGA TCATGACCGA 
ATGTACACCG TCCTGAAGGA GTCCGGATTG GACTATATAG CAGCCATGCC TCCACATATT 
GCTGGTGACA AGCCTTTGAC GGAGAAATAC ATTGTGACTG AGAACATGCT AAAAGGAAGG 
GTGATCTCCA AATATGATCT GGGCCATTTC TTTGTCAAGT GCCTGTCCAC TTCTGAATGG 
GATGGAAAGA CAGTTGGCAT TTGTGGAGAG TATAGTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001002686.1
CDS	172..750
Translation	MTGLATLPIAVASGYNVTVLVRDPARLPPDHKASRVVVGDVLNKNDVKKTLEGQDAVIIILGTRNDLSPTTMMSEGTRNIVEVMKARGIRKVVGCMSAFLLWDRSKVPPRLVPVTEDHDRMYTVLKESGLDYIAAMPPHIAGDKPLTEKYIVTENMLKGRVISKYDLGHFFVKCLSTSEWDGKTVGICGEYS

Target ORF information:

RefSeq Version	NM_001002686.1
Organism	Danio rerio(zebrafish)
Definition	Danio rerio biliverdin reductase B (blvrb), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001002686.1

ORF Insert Sequence:

ATGACGGGGT TAGCGACCTT ACCTATCGCA GTGGCCTCAG GTTACAATGT GACGGTGCTG 
GTGAGAGACC CTGCAAGGCT TCCTCCAGAT CATAAGGCCT CCAGAGTGGT TGTGGGAGAC 
GTTCTGAACA AAAACGATGT AAAGAAGACC CTGGAGGGTC AGGATGCAGT CATCATCATT 
CTAGGGACAA GGAATGATCT CAGTCCCACA ACGATGATGT CTGAGGGAAC GCGGAACATC 
GTGGAGGTCA TGAAAGCTCG TGGAATCCGC AAAGTTGTTG GATGCATGTC AGCATTCCTC 
TTGTGGGATC GATCCAAAGT TCCTCCTCGC TTGGTGCCGG TCACTGAAGA TCATGACCGA 
ATGTACACCG TCCTGAAGGA GTCCGGATTG GACTATATAG CAGCCATGCC TCCACATATT 
GCTGGTGACA AGCCTTTGAC GGAGAAATAC ATTGTGACTG AGAACATGCT AAAAGGAAGG 
GTGATCTCCA AATATGATCT GGGCCATTTC TTTGTCAAGT GCCTGTCCAC TTCTGAATGG 
GATGGAAAGA CAGTTGGCAT TTGTGGAGAG TATAGTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Evolution of complexity in the zebrafish synapse proteome.
Nature communications814613(2017 Mar)
Bay?s ?,Collins MO,Reig-Viader R,Gou G,Goulding D,Izquierdo A,Choudhary JS,Emes RD,Grant SG

Spatiotemporal expression and transcriptional regulation of heme oxygenase and biliverdin reductase genes in zebrafish (Danio rerio) suggest novel roles during early developmental periods of heightened oxidative stress.
Comparative biochemistry and physiology. Toxicology & pharmacology : CBP191138-151(2017 Jan)
Holowiecki A,O'Shields B,Jenny MJ

Characterization of heme oxygenase and biliverdin reductase gene expression in zebrafish (Danio rerio): Basal expression and response to pro-oxidant exposures.
Toxicology and applied pharmacology31174-87(2016 Nov)
Holowiecki A,O'Shields B,Jenny MJ

Proteomic profile of zebrafish brain based on two-dimensional gel electrophoresis matrix-assisted laser desorption/ionization MS/MS analysis.
Zebrafish7(2)169-77(2010 Jun)
Singh SK,Sundaram CS,Shanbhag S,Idris MM

Loss of gata1 but not gata2 converts erythropoiesis to myelopoiesis in zebrafish embryos.
Developmental cell8(1)109-16(2005 Jan)
Galloway JL,Wingert RA,Thisse C,Thisse B,Zon LI