cops5 cDNA ORF clone, Danio rerio(zebrafish)

Gene
Clones
gRNAs

Summary

Gene Symbol	cops5
Entrez Gene ID	393698
Full Name	COP9 signalosome subunit 5
Synonyms	zgc:73130
General protein information	Preferred Names COP9 signalosome subunit 5 Names COP9 signalosome complex subunit 5 COP9 constitutive photomorphogenic homolog subunit 5 signalosome subunit 5
Gene Type	protein-coding
Organism	Danio rerio(zebrafish)

mRNA and Protein(s)

mRNA	Protein	Name
NM_200725.1	NP_957019.1	COP9 signalosome complex subunit 5

Pathways from BioSystems

Homologies

Homo sapiens (human)	COPS5	NP_006828.2
Bos taurus (cattle)	COPS5	NP_001179068.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP002880	XP_312032.5
Mus musculus (house mouse)	Cops5	NP_038743.1
Arabidopsis thaliana (thale cress)	CSN5B	NP_177279.1
Oryza sativa (rice)	Os04g0654700	NP_001054112.1
Xenopus tropicalis (tropical clawed frog)	cops5	NP_989109.1
Pan troglodytes (chimpanzee)	COPS5	XP_001162723.1
Canis lupus familiaris (dog)	COPS5	XP_005638087.1
Gallus gallus (chicken)	COPS5	NP_001034400.1
Drosophila melanogaster (fruit fly)	CSN5	NP_477442.1
Caenorhabditis elegans (roundworm)	csn-5	NP_500841.1
Magnaporthe oryzae (rice blast fungus)	MGG_05274	XP_003712833.1
Neurospora crassa	NCU00467	XP_956786.1
	COPS5	XP_001097856.1
Rattus norvegicus (Norway rat)	Cops5	NP_001020866.1
Danio rerio (zebrafish)	cops5	NP_957019.1
Arabidopsis thaliana (thale cress)	CSN5A	NP_173705.1

Gene Ontology
Bibliography

Related articles in PubMed

The role of jab1, a putative downstream effector of the neurotrophic cytokine macrophage migration inhibitory factor (MIF) in zebrafish inner ear hair cell development.
Weber LJ, Marcy HK, Shen YC, Tomkovich SE, Brooks KM, Hilk KE, Barald KF
Experimental neurology(2017 Sep)

Evolution of complexity in the zebrafish synapse proteome.
Bay?s ?, Collins MO, Reig-Viader R, Gou G, Goulding D, Izquierdo A, Choudhary JS, Emes RD, Grant SG
Nature communications814613(2017 Mar)

RFX transcription factors are essential for hearing in mice.
Elkon R, Milon B, Morrison L, Shah M, Vijayakumar S, Racherla M, Leitch CC, Silipino L, Hadi S, Weiss-Gayet M, Barras E, Schmid CD, Ait-Lounis A, Barnes A, Song Y, Eisenman DJ, Eliyahu E, Frolenkov GI, Strome SE, Durand B, Zaghloul NA, Jones SM, Reith W, Hertzano R
Nature communications68549(2015 Oct)

Benzo[a]pyrene exposure influences the cardiac development and the expression of cardiovascular relative genes in zebrafish (Danio rerio) embryos.
Huang L, Wang C, Zhang Y, Li J, Zhong Y, Zhou Y, Chen Y, Zuo Z
Chemosphere87(4)369-75(2012 Apr)

Genome-wide loss-of-function analysis of deubiquitylating enzymes for zebrafish development.
Tse WK, Eisenhaber B, Ho SH, Ng Q, Eisenhaber F, Jiang YJ
BMC genomics10637(2009 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following cops5 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the cops5 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ODa02904	NM_200725.1 Latest version!	Danio rerio COP9 signalosome subunit 5 (cops5), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$258.30 $369.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

cops5 ( NM_200725.1 ) cDNA ORF clone, Danio rerio(zebrafish) -> NP_957019.1 Danio rerio COP9 signalosome subunit 5 (cops5), mRNA.

Price & Availability↑

CloneID	ODa02904
Clone ID Related Accession (Same CDS sequence)	NM_200725.1
Accession Version	NM_200725.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1005bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-25
Organism	Danio rerio(zebrafish)
Product	COP9 signalosome complex subunit 5
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC059493.1. ##Evidence-Data-START## Transcript exon combination :: EE684876.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2168446, SAMEA2168447 [ECO:0000348] ##Evidence-Data-END##

ATGGCTGGCA GTAGCATAGC GATGAAAACA TGGGAGCTGT CAAACAGCAT GCAGGAAGTT 
CAGAGTATCG ACGAAATATA TAAATATGAC AAAAAACAAC AACAAGAAAT TCTGGCGGCC 
AAACCGTGGA CTAAAGATCA TCATTATTTT AAATACTGCA AGCTATCGGC GTTGGCACTG 
CTGAAGATGG TGATGCACGC TAGATCTGGA GGAAACCTGG AGGTGATGGG ACTTATGCTG 
GGGAAGGTGG ATGGAGAGAC CATGATCATC ATGGACAGTT TTGCTTTACC AGTGGAAGGC 
ACTGAAACCA GAGTCAACGC TCAGGCTGCA GCCTATGAAT ACATGGCTGC TTATATAGAG 
AATGCTAAAC AGGTGGGGCG GTTGGAGAAT GCCATTGGAT GGTACCACAG TCATCCAGGA 
TACGGCTGCT GGCTTTCAGG CATAGATGTC AGCACTCAGA TGCTTAACCA GCAGTTTCAA 
GAGCCCTTTG TCGCAGTAGT GATCGATCCC ACAAGGACTA TATCCGCAGG GAAGGTCAAT 
CTTGGAGCTT TCAGGACATA TCCGAAGGGT TACAAGCCTC CAGATGAGGG TCCTTCTGAA 
TACCAGACGA TACCTCTTAA CAAAATTGAG GATTTTGGAG TGCATTGCAA ACAGTATTAT 
GCATTAGAAG TGTCTTATTT TAAGTCTTCC CTGGACCGCA AACTCCTAGA GCTGCTGTGG 
AATAAGTATT GGGTCAACAC TTTGAGCTCC TCAAGCCTAC TGACAAATGC AGACTACACC 
ACCGGACAGG TGTTTGACTT GTCTGAGAAG CTGGAGCAGG CGGAAGCGCA GCTGGGACGA 
GGCAGCTTCA TGCTGGGCTT GGACACACAT GATAGAAAAT CTGAGGACAA ACTAGCAAAG 
GCAACACGTG ACAGCTGCAA AACAACCATT GAAGCGATTC ATGGTTTGAT GTCCCAGGTA 
ATCAAAGATA AACTCTTCAA TCAAGTGAAC ACATCTGCCA ACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_957019.1
CDS	181..1185
Translation	MAGSSIAMKTWELSNSMQEVQSIDEIYKYDKKQQQEILAAKPWTKDHHYFKYCKLSALALLKMVMHARSGGNLEVMGLMLGKVDGETMIIMDSFALPVEGTETRVNAQAAAYEYMAAYIENAKQVGRLENAIGWYHSHPGYGCWLSGIDVSTQMLNQQFQEPFVAVVIDPTRTISAGKVNLGAFRTYPKGYKPPDEGPSEYQTIPLNKIEDFGVHCKQYYALEVSYFKSSLDRKLLELLWNKYWVNTLSSSSLLTNADYTTGQVFDLSEKLEQAEAQLGRGSFMLGLDTHDRKSEDKLAKATRDSCKTTIEAIHGLMSQVIKDKLFNQVNTSAN

Target ORF information:

RefSeq Version	NM_200725.1
Organism	Danio rerio(zebrafish)
Definition	Danio rerio COP9 signalosome subunit 5 (cops5), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_200725.1

ORF Insert Sequence:

ATGGCTGGCA GTAGCATAGC GATGAAAACA TGGGAGCTGT CAAACAGCAT GCAGGAAGTT 
CAGAGTATCG ACGAAATATA TAAATATGAC AAAAAACAAC AACAAGAAAT TCTGGCGGCC 
AAACCGTGGA CTAAAGATCA TCATTATTTT AAATACTGCA AGCTATCGGC GTTGGCACTG 
CTGAAGATGG TGATGCACGC TAGATCTGGA GGAAACCTGG AGGTGATGGG ACTTATGCTG 
GGGAAGGTGG ATGGAGAGAC CATGATCATC ATGGACAGTT TTGCTTTACC AGTGGAAGGC 
ACTGAAACCA GAGTCAACGC TCAGGCTGCA GCCTATGAAT ACATGGCTGC TTATATAGAG 
AATGCTAAAC AGGTGGGGCG GTTGGAGAAT GCCATTGGAT GGTACCACAG TCATCCAGGA 
TACGGCTGCT GGCTTTCAGG CATAGATGTC AGCACTCAGA TGCTTAACCA GCAGTTTCAA 
GAGCCCTTTG TCGCAGTAGT GATCGATCCC ACAAGGACTA TATCCGCAGG GAAGGTCAAT 
CTTGGAGCTT TCAGGACATA TCCGAAGGGT TACAAGCCTC CAGATGAGGG TCCTTCTGAA 
TACCAGACGA TACCTCTTAA CAAAATTGAG GATTTTGGAG TGCATTGCAA ACAGTATTAT 
GCATTAGAAG TGTCTTATTT TAAGTCTTCC CTGGACCGCA AACTCCTAGA GCTGCTGTGG 
AATAAGTATT GGGTCAACAC TTTGAGCTCC TCAAGCCTAC TGACAAATGC AGACTACACC 
ACCGGACAGG TGTTTGACTT GTCTGAGAAG CTGGAGCAGG CGGAAGCGCA GCTGGGACGA 
GGCAGCTTCA TGCTGGGCTT GGACACACAT GATAGAAAAT CTGAGGACAA ACTAGCAAAG 
GCAACACGTG ACAGCTGCAA AACAACCATT GAAGCGATTC ATGGTTTGAT GTCCCAGGTA 
ATCAAAGATA AACTCTTCAA TCAAGTGAAC ACATCTGCCA ACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

The role of jab1, a putative downstream effector of the neurotrophic cytokine macrophage migration inhibitory factor (MIF) in zebrafish inner ear hair cell development.
Experimental neurology(2017 Sep)
Weber LJ,Marcy HK,Shen YC,Tomkovich SE,Brooks KM,Hilk KE,Barald KF

Evolution of complexity in the zebrafish synapse proteome.
Nature communications814613(2017 Mar)
Bay?s ?,Collins MO,Reig-Viader R,Gou G,Goulding D,Izquierdo A,Choudhary JS,Emes RD,Grant SG

RFX transcription factors are essential for hearing in mice.
Nature communications68549(2015 Oct)
Elkon R,Milon B,Morrison L,Shah M,Vijayakumar S,Racherla M,Leitch CC,Silipino L,Hadi S,Weiss-Gayet M,Barras E,Schmid CD,Ait-Lounis A,Barnes A,Song Y,Eisenman DJ,Eliyahu E,Frolenkov GI,Strome SE,Durand B,Zaghloul NA,Jones SM,Reith W,Hertzano R

Benzo[a]pyrene exposure influences the cardiac development and the expression of cardiovascular relative genes in zebrafish (Danio rerio) embryos.
Chemosphere87(4)369-75(2012 Apr)
Huang L,Wang C,Zhang Y,Li J,Zhong Y,Zhou Y,Chen Y,Zuo Z

Genome-wide loss-of-function analysis of deubiquitylating enzymes for zebrafish development.
BMC genomics10637(2009 Dec)
Tse WK,Eisenhaber B,Ho SH,Ng Q,Eisenhaber F,Jiang YJ