pdcd2 cDNA ORF clone, Danio rerio(zebrafish)

Gene
Clones
gRNAs

Summary

Gene Symbol	pdcd2
Entrez Gene ID	393370
Full Name	programmed cell death 2
Synonyms	zgc:63685
General protein information	Preferred Names programmed cell death 2 Names programmed cell death protein 2
Gene Type	protein-coding
Organism	Danio rerio(zebrafish)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001045138.1	NP_001038603.1	programmed cell death protein 2

Pathways from BioSystems

Homologies

Rattus norvegicus (Norway rat)	Pdcd2	NP_113826.1
Homo sapiens (human)	PDCD2	NP_002589.2
Pan troglodytes (chimpanzee)	PDCD2	XP_520603.2
	PDCD2	XP_001086513.1
Canis lupus familiaris (dog)	PDCD2	XP_854542.1
Gallus gallus (chicken)	PDCD2	NP_001026235.1
Arabidopsis thaliana (thale cress)	AT4G02220	NP_567225.1
Xenopus tropicalis (tropical clawed frog)	pdcd2	XP_002931535.1
Drosophila melanogaster (fruit fly)	Zfrp8	NP_611890.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP005582	XP_315591.4
Oryza sativa (rice)	Os03g0300200	NP_001049855.1
Bos taurus (cattle)	PDCD2	NP_001039574.1
Mus musculus (house mouse)	Pdcd2	NP_032825.2
Danio rerio (zebrafish)	pdcd2	NP_001038603.1
Caenorhabditis elegans (roundworm)	pdcd-2	NP_497896.1

Gene Ontology
Bibliography

Related articles in PubMed

Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.
Pasquier J, Cabau C, Nguyen T, Jouanno E, Severac D, Braasch I, Journot L, Pontarotti P, Klopp C, Postlethwait JH, Guiguen Y, Bobe J
BMC genomics17368(2016 05)

RFX transcription factors are essential for hearing in mice.
Elkon R, Milon B, Morrison L, Shah M, Vijayakumar S, Racherla M, Leitch CC, Silipino L, Hadi S, Weiss-Gayet M, Barras E, Schmid CD, Ait-Lounis A, Barnes A, Song Y, Eisenman DJ, Eliyahu E, Frolenkov GI, Strome SE, Durand B, Zaghloul NA, Jones SM, Reith W, Hertzano R
Nature communications68549(2015 Oct)

PDCD2 controls hematopoietic stem cell differentiation during development.
Kramer J, Granier CJ, Davis S, Piso K, Hand J, Rabson AB, Sabaawy HE
Stem cells and development22(1)58-72(2013 Jan)

Comparative analysis of the PDCD2-TBP-PSMB1 region in vertebrates.
Trachtulec Z, Vlcek C, Mihola O, Forejt J
Gene335151-7(2004 Jun)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

pdcd2 plays a critical role in regulating the transcriptional hierarchy controlling hematopoietic lineage determination.
Title: PDCD2 controls hematopoietic stem cell differentiation during development.

The following pdcd2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the pdcd2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ODa31940	NM_001045138.1 Latest version!	Danio rerio programmed cell death 2 (pdcd2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$258.30 $369.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

pdcd2 ( NM_001045138.1 ) cDNA ORF clone, Danio rerio(zebrafish) -> NP_001038603.1 Danio rerio programmed cell death 2 (pdcd2), mRNA.

Price & Availability↑

CloneID	ODa31940
Clone ID Related Accession (Same CDS sequence)	NM_001045138.1
Accession Version	NM_001045138.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1077bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-11-23
Organism	Danio rerio(zebrafish)
Product	programmed cell death protein 2
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AL772388.35. On or before Apr 21, 2008 this sequence version replaced NM_200399.1, XM_690925.1. ##Evidence-Data-START## Transcript exon combination :: BC054132.1, GDQH01007701.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2168446, SAMEA2168447 [ECO:0000348] ##Evidence-Data-END##

ATGGCTGCAA ATACATTGAA AGAGTCAAAT ACACACAGTG ACGTCGTGCT GGGCTTCTTA 
GAGGAGGCAG AATCATGGCA GCTTCTGAGT GACCAGTTTC CAAGTAAAGT CGGCGGGCGA 
CCAGCGTGGC TGAGCCAGTC GGATTTACCA GCCGTGTCTG AGTTACAGTG CGAGGAGTGC 
AAACTGCCGG CGGTGTTTCT TCTGCAGGTC TATGCGCCAG TCACTGAATA TGATCGATGT 
TTTCACAGGA CACTGTTTGT GTTCTGCTGC AAGACACCAG CCTGCTATAC TCGAAACGAC 
AGCAAGTGTT TTAAAGTGTT CAGAAGTCAG TTACCAAGGA AAAATGAGTT TTACCCTTTT 
AATCCTCCTC CTGACGAAAA GCCTGAACAG CCAGTACATG ATGCTCAGGT TTTGGGTTCA 
GGACTCAAAC TGTGCAGGCT GTGTGGTTGT CTGGGACAGA AAGCCTGCTC TCGATGTCAC 
TCTGTCACAT ATTGCTGTAA GGAGCATCAG ACCACAGACT GGAAACAAAG ACACAAGAAA 
GAGTGCTTAG CTGAGGCTTC TCAAGTTTCA GGGGAGCTGA ATTCATTTCT GTTTCCTGAG 
TGGGAGCTGG TCACCGAACC AGAGGTGATT CCGGCAAAAG ATGAACTTCA GGAATCCCCC 
AGTCTGGATC AGGAGAACAT TGCATCTTTA AATAGCGGTT TGGAGGACAG TGAGCTGGAG 
AGTATGGCTC TTCATGAAAC GTTAGACTCC AAAGTCTTTC AAAAGTTCAA GCAGCGCATT 
GCTAATGAGC CACAACAGGT TTTGCGGTAT TGTAGAGGGG GATCTCCTCT TTGGGTGACA 
GCTGAACATG TGCCACGTGA AGAGGAAGTT CCAGAGTGTA CATGTGGCGC AAAACGGCTC 
TTTGAATTCC AGATAATGCC CCAATTACTA AATCACCTGA AAGTGGACAG TACAGATGCC 
AGCATAGACT GGGGGACAGT GGCCATCTAC ACCTGTGCTG AAAGCTGTGA TCAAGGCAAC 
AAATATTCCC CTGAGTTCAT CTGGAAACAA GACTTTTCAG GAGATCAAGC AGAGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001038603.1
CDS	102..1178
Translation	MAANTLKESNTHSDVVLGFLEEAESWQLLSDQFPSKVGGRPAWLSQSDLPAVSELQCEECKLPAVFLLQVYAPVTEYDRCFHRTLFVFCCKTPACYTRNDSKCFKVFRSQLPRKNEFYPFNPPPDEKPEQPVHDAQVLGSGLKLCRLCGCLGQKACSRCHSVTYCCKEHQTTDWKQRHKKECLAEASQVSGELNSFLFPEWELVTEPEVIPAKDELQESPSLDQENIASLNSGLEDSELESMALHETLDSKVFQKFKQRIANEPQQVLRYCRGGSPLWVTAEHVPREEEVPECTCGAKRLFEFQIMPQLLNHLKVDSTDASIDWGTVAIYTCAESCDQGNKYSPEFIWKQDFSGDQAE

Target ORF information:

RefSeq Version	NM_001045138.1
Organism	Danio rerio(zebrafish)
Definition	Danio rerio programmed cell death 2 (pdcd2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001045138.1

ORF Insert Sequence:

ATGGCTGCAA ATACATTGAA AGAGTCAAAT ACACACAGTG ACGTCGTGCT GGGCTTCTTA 
GAGGAGGCAG AATCATGGCA GCTTCTGAGT GACCAGTTTC CAAGTAAAGT CGGCGGGCGA 
CCAGCGTGGC TGAGCCAGTC GGATTTACCA GCCGTGTCTG AGTTACAGTG CGAGGAGTGC 
AAACTGCCGG CGGTGTTTCT TCTGCAGGTC TATGCGCCAG TCACTGAATA TGATCGATGT 
TTTCACAGGA CACTGTTTGT GTTCTGCTGC AAGACACCAG CCTGCTATAC TCGAAACGAC 
AGCAAGTGTT TTAAAGTGTT CAGAAGTCAG TTACCAAGGA AAAATGAGTT TTACCCTTTT 
AATCCTCCTC CTGACGAAAA GCCTGAACAG CCAGTACATG ATGCTCAGGT TTTGGGTTCA 
GGACTCAAAC TGTGCAGGCT GTGTGGTTGT CTGGGACAGA AAGCCTGCTC TCGATGTCAC 
TCTGTCACAT ATTGCTGTAA GGAGCATCAG ACCACAGACT GGAAACAAAG ACACAAGAAA 
GAGTGCTTAG CTGAGGCTTC TCAAGTTTCA GGGGAGCTGA ATTCATTTCT GTTTCCTGAG 
TGGGAGCTGG TCACCGAACC AGAGGTGATT CCGGCAAAAG ATGAACTTCA GGAATCCCCC 
AGTCTGGATC AGGAGAACAT TGCATCTTTA AATAGCGGTT TGGAGGACAG TGAGCTGGAG 
AGTATGGCTC TTCATGAAAC GTTAGACTCC AAAGTCTTTC AAAAGTTCAA GCAGCGCATT 
GCTAATGAGC CACAACAGGT TTTGCGGTAT TGTAGAGGGG GATCTCCTCT TTGGGTGACA 
GCTGAACATG TGCCACGTGA AGAGGAAGTT CCAGAGTGTA CATGTGGCGC AAAACGGCTC 
TTTGAATTCC AGATAATGCC CCAATTACTA AATCACCTGA AAGTGGACAG TACAGATGCC 
AGCATAGACT GGGGGACAGT GGCCATCTAC ACCTGTGCTG AAAGCTGTGA TCAAGGCAAC 
AAATATTCCC CTGAGTTCAT CTGGAAACAA GACTTTTCAG GAGATCAAGC AGAGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.
BMC genomics17368(2016 05)
Pasquier J,Cabau C,Nguyen T,Jouanno E,Severac D,Braasch I,Journot L,Pontarotti P,Klopp C,Postlethwait JH,Guiguen Y,Bobe J

RFX transcription factors are essential for hearing in mice.
Nature communications68549(2015 Oct)
Elkon R,Milon B,Morrison L,Shah M,Vijayakumar S,Racherla M,Leitch CC,Silipino L,Hadi S,Weiss-Gayet M,Barras E,Schmid CD,Ait-Lounis A,Barnes A,Song Y,Eisenman DJ,Eliyahu E,Frolenkov GI,Strome SE,Durand B,Zaghloul NA,Jones SM,Reith W,Hertzano R

PDCD2 controls hematopoietic stem cell differentiation during development.
Stem cells and development22(1)58-72(2013 Jan)
Kramer J,Granier CJ,Davis S,Piso K,Hand J,Rabson AB,Sabaawy HE

Comparative analysis of the PDCD2-TBP-PSMB1 region in vertebrates.
Gene335151-7(2004 Jun)
Trachtulec Z,Vlcek C,Mihola O,Forejt J