thoc1 cDNA ORF clone, Danio rerio(zebrafish)

Gene
Clones
gRNAs

Summary

Gene Symbol	thoc1
Entrez Gene ID	373077
Full Name	THO complex 1
Synonyms	p84
General protein information	Preferred Names THO complex 1 Names THO complex subunit 1
Gene Type	protein-coding
Organism	Danio rerio(zebrafish)

mRNA and Protein(s)

mRNA	Protein	Name
NM_201324.1	NP_958481.1	THO complex subunit 1

Pathways from BioSystems

Homologies

Bos taurus (cattle)	THOC1	NP_001192409.1
Canis lupus familiaris (dog)	THOC1	XP_547651.2
Mus musculus (house mouse)	Thoc1	NP_705780.1
Drosophila melanogaster (fruit fly)	Hpr1	NP_649594.1
Caenorhabditis elegans (roundworm)	thoc-1	NP_493796.2
Gallus gallus (chicken)	THOC1	XP_419149.4
Homo sapiens (human)	THOC1	NP_005122.2
	THOC1	XP_001090085.1
Danio rerio (zebrafish)	thoc1	NP_958481.1
Pan troglodytes (chimpanzee)	THOC1	XP_512049.2
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP004070	XP_309625.4
Xenopus tropicalis (tropical clawed frog)	thoc1	XP_002934170.1

Gene Ontology
Bibliography

Related articles in PubMed

RFX transcription factors are essential for hearing in mice.
Elkon R, Milon B, Morrison L, Shah M, Vijayakumar S, Racherla M, Leitch CC, Silipino L, Hadi S, Weiss-Gayet M, Barras E, Schmid CD, Ait-Lounis A, Barnes A, Song Y, Eisenman DJ, Eliyahu E, Frolenkov GI, Strome SE, Durand B, Zaghloul NA, Jones SM, Reith W, Hertzano R
Nature communications68549(2015 Oct)

A new mib allele with a chromosomal deletion covering foxc1a exhibits anterior somite specification defect.
Hsu CH, Lin JS, Po Lai K, Li JW, Chan TF, You MS, Tse WK, Jiang YJ
Scientific reports510673(2015 Jun)

Sublethal effects of waterborne uranium exposures on the zebrafish brain: transcriptional responses and alterations of the olfactory bulb ultrastructure.
Lerebours A, Bourdineaud JP, van der Ven K, Vandenbrouck T, Gonzalez P, Camilleri V, Floriani M, Garnier-Laplace J, Adam-Guillermin C
Environmental science & technology44(4)1438-43(2010 Feb)

Genes with homology to mammalian apoptosis regulators identified in zebrafish.
Inohara N, Nu?ez G
Cell death and differentiation7(5)509-10(2000 May)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following thoc1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the thoc1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ODa34712	NM_201324.1 Latest version!	Danio rerio THO complex 1 (thoc1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$342.30 $489.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

thoc1 ( NM_201324.1 ) cDNA ORF clone, Danio rerio(zebrafish) -> NP_958481.1 Danio rerio THO complex 1 (thoc1), mRNA.

Price & Availability↑

CloneID	ODa34712
Clone ID Related Accession (Same CDS sequence)	NM_201324.1
Accession Version	NM_201324.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1968bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-11-23
Organism	Danio rerio(zebrafish)
Product	THO complex subunit 1
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC054938.1. On Jul 6, 2005 this sequence version replaced XM_697403.1. ##Evidence-Data-START## Transcript exon combination :: BC054938.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2168446, SAMEA2168447 [ECO:0000348] ##Evidence-Data-END##

ATGTCTCCTC CGTCTCACTT CGACTTCATT GAAGCCAGAG ATAAATTTAC GGTTGCCACT 
AAAAATGCGG TTGATACCAG GAACTGTAAG CCTCTGACCA CCGCTTTCAG TCATCTTCCT 
GGAAACGAAA CGGAGAAAAA GGCCACACTT GATCAAGCTC TGCGTGGAGT TCTGGAAGAG 
CAGATAGTAA ATCAGAAAGT GAATGTTGAC GACTTCCTTT CTTTAATCTA CATCAGTATT 
GATGGTGTGA CTGAAGGCAT CTGCTCTGCT ACCACTCCTT TCCTTCTGCT GGGAGATGTG 
CTGGACTGTC TGCCTCTGGA TCAGTGTGAC AAAATCTTCT CCTTTGTCGA AGAAAACGTA 
TCTACTTGGA AGTCTAACAC ATTTTACTCT GCTGGGAAAA ACTACTTGTT AAGGATGTGC 
AACGACCTCC TCAGAAGACT CTCTAAATCT CAGAACACGG TGTTTTGTGG ACGAATCCAG 
CTGTTTTTAG CACGTCTCTT CCCCCTGTCG GAAAAATCAG GACTAAACCT ACAGAGCCAG 
TTCAACCTTG ATAACATCAC AGTGTTCAAC AAAAATGAGC AGGACAGCAC ACTGGGACAG 
CAGCACACAG AGGTTAAGGA GGAAGGAATG GATGTGGAGG AGGGAGAAAT GGGGGATGAA 
GATGCTCCTG CTCCAAGCTC CATTCCTATT GACTACAACT TGTACAGAAA ATTCTGGACC 
CTGCAGGACT ATTTCAGAAA CCCTGTTCAG TGCTACGACA AGTTCTCCTG GATGACTTTC 
ATTAAGTATT CAGATGAGGC GCTAGCCGTC TTCAAGAGCT TTAAACTGGA TGACATGCAG 
GCGTCAAAGA AAAAGCTGGA GGAGATGAGA ACCTCTTCTG GAGATCATGT CTATTTTGCC 
AAGTTCCTGA CCAGTGAGAA ATTGATGGAT CTTCAGCTGA GCGACAGCAA CTTCAGAAGA 
CACATTCTCC TGCAGTACCT CATCCTCTTC CAGTATCTCA AGGGCCAGGT CAAGTTTAAG 
AGTTCCAGCT GTGTTTTGAA TGACGATCAA TCTTTGTGGA TCGAGGACAC AACCAAACTA 
GTCTATCAGT TGCTGAAAGA AATCCCTCCA GATGGGGACA AGTTTGGATC AATGGTTGAA 
CACATCCTGA ACACAGAGGA AAACTGGAAC TCTTGGAAAA ATGAAGGCTG TCCGAGCTTT 
GTGAAGGAGA GACCCGCAGA GACTAAACCC ATCCGGCCCA GCAGGAAGAG ACAAGCACCA 
GAAGACTTCT TGGGGAAGGG CCCTGATCGC AAAATCCTGA TGGGAAACGA CGAGCTCACG 
AGGCTCTGGA ATCTGAACCC CGACAATATG GAGGCCTGCA AGTCAGAAAA CAGGGAATTC 
ATGCCGTCAC TGGAGGATTT CTTTGAAGAA GCCATCGAAC AGGCAGATCC AGCAAACATG 
GTGGAGGACG AATACAAAGT CGTGCGAAAC TCAAACTACG GTTGGCGAGC GCTGCGCCTG 
CTGTCCAGGA GGAGTCCGCA CTTCTTCCAG CCCACAAACC AGCAGTTCAA GAGTCTGGCC 
GACTATCTGG AGAACATGGT CATCAAACTG GCCAAAGAGC TGCCCAAAGA CATTCCTTCT 
GAGGAGATTA AAACCGGAGA GGAGGATGAT GATGAGAATG GAGATAACCT GCTGAAGGAC 
AGTAATGACA GTCCCAGCAT TCAAAGCAAA GCTGTGACCA ACAGCCAAAT GGACGAAATC 
GCAGCAAAAC TCGGCTCCCA ATGGAAAACA CTGGCGGATC ATCTGGAAAT GAGTGACAAG 
GAGATCAGAG TGATCGAGTC GGACAGCGAG GATGTGGATC TACAGGCCAA AATGCTCCTG 
GTGGCCTGGC AGGACCGAGA AGGCTCCCAA GCAACGATGG AGAGCCTGGT CACGGCCCTG 
AACGCAGCCG GTTTCAACAA CATCGCAGAT AATCTGAGCG AAACATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_958481.1
CDS	34..2001
Translation	MSPPSHFDFIEARDKFTVATKNAVDTRNCKPLTTAFSHLPGNETEKKATLDQALRGVLEEQIVNQKVNVDDFLSLIYISIDGVTEGICSATTPFLLLGDVLDCLPLDQCDKIFSFVEENVSTWKSNTFYSAGKNYLLRMCNDLLRRLSKSQNTVFCGRIQLFLARLFPLSEKSGLNLQSQFNLDNITVFNKNEQDSTLGQQHTEVKEEGMDVEEGEMGDEDAPAPSSIPIDYNLYRKFWTLQDYFRNPVQCYDKFSWMTFIKYSDEALAVFKSFKLDDMQASKKKLEEMRTSSGDHVYFAKFLTSEKLMDLQLSDSNFRRHILLQYLILFQYLKGQVKFKSSSCVLNDDQSLWIEDTTKLVYQLLKEIPPDGDKFGSMVEHILNTEENWNSWKNEGCPSFVKERPAETKPIRPSRKRQAPEDFLGKGPDRKILMGNDELTRLWNLNPDNMEACKSENREFMPSLEDFFEEAIEQADPANMVEDEYKVVRNSNYGWRALRLLSRRSPHFFQPTNQQFKSLADYLENMVIKLAKELPKDIPSEEIKTGEEDDDENGDNLLKDSNDSPSIQSKAVTNSQMDEIAAKLGSQWKTLADHLEMSDKEIRVIESDSEDVDLQAKMLLVAWQDREGSQATMESLVTALNAAGFNNIADNLSET

Target ORF information:

RefSeq Version	NM_201324.1
Organism	Danio rerio(zebrafish)
Definition	Danio rerio THO complex 1 (thoc1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_201324.1

ORF Insert Sequence:

ATGTCTCCTC CGTCTCACTT CGACTTCATT GAAGCCAGAG ATAAATTTAC GGTTGCCACT 
AAAAATGCGG TTGATACCAG GAACTGTAAG CCTCTGACCA CCGCTTTCAG TCATCTTCCT 
GGAAACGAAA CGGAGAAAAA GGCCACACTT GATCAAGCTC TGCGTGGAGT TCTGGAAGAG 
CAGATAGTAA ATCAGAAAGT GAATGTTGAC GACTTCCTTT CTTTAATCTA CATCAGTATT 
GATGGTGTGA CTGAAGGCAT CTGCTCTGCT ACCACTCCTT TCCTTCTGCT GGGAGATGTG 
CTGGACTGTC TGCCTCTGGA TCAGTGTGAC AAAATCTTCT CCTTTGTCGA AGAAAACGTA 
TCTACTTGGA AGTCTAACAC ATTTTACTCT GCTGGGAAAA ACTACTTGTT AAGGATGTGC 
AACGACCTCC TCAGAAGACT CTCTAAATCT CAGAACACGG TGTTTTGTGG ACGAATCCAG 
CTGTTTTTAG CACGTCTCTT CCCCCTGTCG GAAAAATCAG GACTAAACCT ACAGAGCCAG 
TTCAACCTTG ATAACATCAC AGTGTTCAAC AAAAATGAGC AGGACAGCAC ACTGGGACAG 
CAGCACACAG AGGTTAAGGA GGAAGGAATG GATGTGGAGG AGGGAGAAAT GGGGGATGAA 
GATGCTCCTG CTCCAAGCTC CATTCCTATT GACTACAACT TGTACAGAAA ATTCTGGACC 
CTGCAGGACT ATTTCAGAAA CCCTGTTCAG TGCTACGACA AGTTCTCCTG GATGACTTTC 
ATTAAGTATT CAGATGAGGC GCTAGCCGTC TTCAAGAGCT TTAAACTGGA TGACATGCAG 
GCGTCAAAGA AAAAGCTGGA GGAGATGAGA ACCTCTTCTG GAGATCATGT CTATTTTGCC 
AAGTTCCTGA CCAGTGAGAA ATTGATGGAT CTTCAGCTGA GCGACAGCAA CTTCAGAAGA 
CACATTCTCC TGCAGTACCT CATCCTCTTC CAGTATCTCA AGGGCCAGGT CAAGTTTAAG 
AGTTCCAGCT GTGTTTTGAA TGACGATCAA TCTTTGTGGA TCGAGGACAC AACCAAACTA 
GTCTATCAGT TGCTGAAAGA AATCCCTCCA GATGGGGACA AGTTTGGATC AATGGTTGAA 
CACATCCTGA ACACAGAGGA AAACTGGAAC TCTTGGAAAA ATGAAGGCTG TCCGAGCTTT 
GTGAAGGAGA GACCCGCAGA GACTAAACCC ATCCGGCCCA GCAGGAAGAG ACAAGCACCA 
GAAGACTTCT TGGGGAAGGG CCCTGATCGC AAAATCCTGA TGGGAAACGA CGAGCTCACG 
AGGCTCTGGA ATCTGAACCC CGACAATATG GAGGCCTGCA AGTCAGAAAA CAGGGAATTC 
ATGCCGTCAC TGGAGGATTT CTTTGAAGAA GCCATCGAAC AGGCAGATCC AGCAAACATG 
GTGGAGGACG AATACAAAGT CGTGCGAAAC TCAAACTACG GTTGGCGAGC GCTGCGCCTG 
CTGTCCAGGA GGAGTCCGCA CTTCTTCCAG CCCACAAACC AGCAGTTCAA GAGTCTGGCC 
GACTATCTGG AGAACATGGT CATCAAACTG GCCAAAGAGC TGCCCAAAGA CATTCCTTCT 
GAGGAGATTA AAACCGGAGA GGAGGATGAT GATGAGAATG GAGATAACCT GCTGAAGGAC 
AGTAATGACA GTCCCAGCAT TCAAAGCAAA GCTGTGACCA ACAGCCAAAT GGACGAAATC 
GCAGCAAAAC TCGGCTCCCA ATGGAAAACA CTGGCGGATC ATCTGGAAAT GAGTGACAAG 
GAGATCAGAG TGATCGAGTC GGACAGCGAG GATGTGGATC TACAGGCCAA AATGCTCCTG 
GTGGCCTGGC AGGACCGAGA AGGCTCCCAA GCAACGATGG AGAGCCTGGT CACGGCCCTG 
AACGCAGCCG GTTTCAACAA CATCGCAGAT AATCTGAGCG AAACATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

RFX transcription factors are essential for hearing in mice.
Nature communications68549(2015 Oct)
Elkon R,Milon B,Morrison L,Shah M,Vijayakumar S,Racherla M,Leitch CC,Silipino L,Hadi S,Weiss-Gayet M,Barras E,Schmid CD,Ait-Lounis A,Barnes A,Song Y,Eisenman DJ,Eliyahu E,Frolenkov GI,Strome SE,Durand B,Zaghloul NA,Jones SM,Reith W,Hertzano R

A new mib allele with a chromosomal deletion covering foxc1a exhibits anterior somite specification defect.
Scientific reports510673(2015 Jun)
Hsu CH,Lin JS,Po Lai K,Li JW,Chan TF,You MS,Tse WK,Jiang YJ

Sublethal effects of waterborne uranium exposures on the zebrafish brain: transcriptional responses and alterations of the olfactory bulb ultrastructure.
Environmental science & technology44(4)1438-43(2010 Feb)
Lerebours A,Bourdineaud JP,van der Ven K,Vandenbrouck T,Gonzalez P,Camilleri V,Floriani M,Garnier-Laplace J,Adam-Guillermin C

Genes with homology to mammalian apoptosis regulators identified in zebrafish.
Cell death and differentiation7(5)509-10(2000 May)
Inohara N,Nu?ez G