cxcl18a.1 cDNA ORF clone, Danio rerio(zebrafish)

Gene
Clones
gRNAs

Summary

Gene Symbol	cxcl18a.1
Entrez Gene ID	100321314
Full Name	chemokine (C-X-C motif) ligand 18a, duplicate 1
Synonyms	cxc46
General protein information	Preferred Names chemokine (C-X-C motif) ligand 18a, duplicate 1 Names chemokine (C-X-C motif) ligand 18a, duplicate 1 CXC chemokine 46 CXC-46 CXCL-chr13b CXCL18aa dareCXC dr-scNA3668-CCL14-26.8-EK2252
Gene Type	protein-coding
Organism	Danio rerio(zebrafish)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001328090.1	NP_001315019.1	chemokine (C-X-C motif) ligand 18a, duplicate 1 precursor

Pathways from BioSystems
Gene Ontology
Bibliography

Related articles in PubMed

The Vascular Niche Regulates Hematopoietic Stem and Progenitor Cell Lodgment and Expansion via klf6a-ccl25b.
Xue Y, Lv J, Zhang C, Wang L, Ma D, Liu F
Developmental cell42(4)349-362.e4(2017 08)

Loss of DNA methylation in zebrafish embryos activates retrotransposons to trigger antiviral signaling.
Chernyavskaya Y, Mudbhary R, Zhang C, Tokarz D, Jacob V, Gopinath S, Sun X, Wang S, Magnani E, Madakashira BP, Yoder JA, Hoshida Y, Sadler KC
Development (Cambridge, England)144(16)2925-2939(2017 08)

The CXCR3-CXCL11 signaling axis mediates macrophage recruitment and dissemination of mycobacterial infection.
Torraca V, Cui C, Boland R, Bebelman JP, van der Sar AM, Smit MJ, Siderius M, Spaink HP, Meijer AH
Disease models & mechanisms8(3)253-69(2015 Mar)

Characterization of samhd1 morphant zebrafish recapitulates features of the human type I interferonopathy Aicardi-Gouti?res syndrome.
Kasher PR, Jenkinson EM, Briolat V, Gent D, Morrissey C, Zeef LA, Rice GI, Levraud JP, Crow YJ
Journal of immunology (Baltimore, Md. : 1950)194(6)2819-25(2015 Mar)

Deficiency in hematopoietic phosphatase ptpn6/Shp1 hyperactivates the innate immune system and impairs control of bacterial infections in zebrafish embryos.
Kanwal Z, Zakrzewska A, den Hertog J, Spaink HP, Schaaf MJ, Meijer AH
Journal of immunology (Baltimore, Md. : 1950)190(4)1631-45(2013 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following cxcl18a.1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the cxcl18a.1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ODa18906	NM_001328090.1 Latest version!	Danio rerio chemokine (C-X-C motif) ligand 18a, duplicate 1 (cxcl18a.1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$104.30 $149.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
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5 or more Clone	50% OFF
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30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

cxcl18a.1 ( NM_001328090.1 ) cDNA ORF clone, Danio rerio(zebrafish) -> NP_001315019.1 Danio rerio chemokine (C-X-C motif) ligand 18a, duplicate 1 (cxcl18a.1), mRNA.

Price & Availability↑

CloneID	ODa18906
Clone ID Related Accession (Same CDS sequence)	NM_001328090.1
Accession Version	NM_001328090.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 363bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-22
Organism	Danio rerio(zebrafish)
Product	chemokine (C-X-C motif) ligand 18a, duplicate 1 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CR762483.10 and EH450744.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: DR720639.1, GDQH01028835.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2168446, SAMEA2168447 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCTTTCA AAACTCTGCA AGCAAGTGTC AAAGTCCTGC TCCTGCTCTC AGTCTGTTCA 
CACTTTATCT CAGTTAAAAT GACAGCTGCA ACATTCATCC GAGAAAAATG TGAGTGTGTT 
AAGGAGGCTG GAGCAGTGCA GTGGAGAAAA ATCACAGACT ACACAATCAC TCCGAAAAAT 
CCTCTTTGCA ACAAGGTTCA AATCAAACTC CAGTTGTCAA ATAAAGAAGT GTGTCTAAAT 
CCAGAGTCCA AGCAGGGGAA AAAACTGCAG AAATGCTGGC AAAAAATTAA CTTCAACCCA 
CAGAGGAAGA AGGTCTGTCT GACGATCAAG AAGAATGCAC CAAAAAGACT CAAGAAGCTT 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001315019.1
CDS	44..406
Translation	MAFKTLQASVKVLLLLSVCSHFISVKMTAATFIREKCECVKEAGAVQWRKITDYTITPKNPLCNKVQIKLQLSNKEVCLNPESKQGKKLQKCWQKINFNPQRKKVCLTIKKNAPKRLKKL

Target ORF information:

RefSeq Version	NM_001328090.1
Organism	Danio rerio(zebrafish)
Definition	Danio rerio chemokine (C-X-C motif) ligand 18a, duplicate 1 (cxcl18a.1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001328090.1

ORF Insert Sequence:

ATGGCTTTCA AAACTCTGCA AGCAAGTGTC AAAGTCCTGC TCCTGCTCTC AGTCTGTTCA 
CACTTTATCT CAGTTAAAAT GACAGCTGCA ACATTCATCC GAGAAAAATG TGAGTGTGTT 
AAGGAGGCTG GAGCAGTGCA GTGGAGAAAA ATCACAGACT ACACAATCAC TCCGAAAAAT 
CCTCTTTGCA ACAAGGTTCA AATCAAACTC CAGTTGTCAA ATAAAGAAGT GTGTCTAAAT 
CCAGAGTCCA AGCAGGGGAA AAAACTGCAG AAATGCTGGC AAAAAATTAA CTTCAACCCA 
CAGAGGAAGA AGGTCTGTCT GACGATCAAG AAGAATGCAC CAAAAAGACT CAAGAAGCTT 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

The Vascular Niche Regulates Hematopoietic Stem and Progenitor Cell Lodgment and Expansion via klf6a-ccl25b.
Developmental cell42(4)349-362.e4(2017 08)
Xue Y,Lv J,Zhang C,Wang L,Ma D,Liu F

Loss of DNA methylation in zebrafish embryos activates retrotransposons to trigger antiviral signaling.
Development (Cambridge, England)144(16)2925-2939(2017 08)
Chernyavskaya Y,Mudbhary R,Zhang C,Tokarz D,Jacob V,Gopinath S,Sun X,Wang S,Magnani E,Madakashira BP,Yoder JA,Hoshida Y,Sadler KC

The CXCR3-CXCL11 signaling axis mediates macrophage recruitment and dissemination of mycobacterial infection.
Disease models & mechanisms8(3)253-69(2015 Mar)
Torraca V,Cui C,Boland R,Bebelman JP,van der Sar AM,Smit MJ,Siderius M,Spaink HP,Meijer AH

Characterization of samhd1 morphant zebrafish recapitulates features of the human type I interferonopathy Aicardi-Gouti?res syndrome.
Journal of immunology (Baltimore, Md. : 1950)194(6)2819-25(2015 Mar)
Kasher PR,Jenkinson EM,Briolat V,Gent D,Morrissey C,Zeef LA,Rice GI,Levraud JP,Crow YJ

Deficiency in hematopoietic phosphatase ptpn6/Shp1 hyperactivates the innate immune system and impairs control of bacterial infections in zebrafish embryos.
Journal of immunology (Baltimore, Md. : 1950)190(4)1631-45(2013 Feb)
Kanwal Z,Zakrzewska A,den Hertog J,Spaink HP,Schaaf MJ,Meijer AH