PDE6G cDNA ORF clone, Canis lupus familiaris(dog)

Gene
Clones
gRNAs

Summary

Gene Symbol	PDE6G
Entrez Gene ID	403911
Full Name	phosphodiesterase 6G
Synonyms	PDEG
General protein information	Preferred Names phosphodiesterase 6G Names retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma GMP-PDE gamma cyclic-GMP phosphodiesterase gamma subunit
Gene Type	protein-coding
Organism	Canis lupus familiaris(dog)

mRNA and Protein(s)

mRNA	Protein	Name
XM_022422536.1	XP_022278244.1	retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma isoform X1
XM_014116188.1	XP_013971663.1	retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma isoform X1
NM_001003235.1	NP_001003235.1	retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma

Pathways from BioSystems

Homologies

Xenopus tropicalis (tropical clawed frog)	pde6g	NP_001165049.1
Homo sapiens (human)	PDE6G	NP_002593.1
Canis lupus familiaris (dog)	PDE6G	NP_001003235.1
Mus musculus (house mouse)	Pde6g	NP_036197.1
Gallus gallus (chicken)	PDE6G	NP_989776.1
Rattus norvegicus (Norway rat)	Pde6g	XP_003751031.1
	LOC719052	XP_001112634.2
Bos taurus (cattle)	PDE6G	NP_776846.1
Danio rerio (zebrafish)	pde6g	NP_997964.1
Xenopus tropicalis (tropical clawed frog)	LOC101732382	XP_004916403.1

Gene Ontology
Bibliography

Related articles in PubMed

Cloning of the cDNA encoding rod photoreceptor cGMP-phosphodiesterase alpha and gamma subunits from the retinal degenerate Labrador retriever dog.
Kylm? T, Paulin L, Hurwitz MY, Hurwitz RL, Kommonen B
Research in veterinary science62(3)293-6(1997 May-Jun)

Cloning and characterization of the cDNA and gene encoding the gamma-subunit of cGMP-phosphodiesterase in canine retinal rod photoreceptor cells.
Wang W, Acland GM, Aguirre GD, Ray K
Gene181(1-2)1-5(1996 Nov)

Elevation of cGMP with normal expression and activity of rod cGMP-PDE in photoreceptor degenerate labrador retrievers.
Kommonen B, Kylma T, Cohen RJ, Penn JS, Paulin L, Hurwitz M, Hurwitz RL
Ophthalmic research28(1)19-28(1996)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following PDE6G gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the PDE6G cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OCe00075	NM_001003235.1 Latest version!	Canis lupus familiaris phosphodiesterase 6G (PDE6G), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$104.30 $149.00
OCe00075	XM_014116188.1 Latest version!	Canis lupus familiaris phosphodiesterase 6G, cGMP-specific, rod, gamma (PDE6G), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$104.30 $149.00
OCe00075	XM_022422536.1 Latest version!	Canis lupus familiaris phosphodiesterase 6G (PDE6G), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$104.30 $149.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

PDE6G ( NM_001003235.1 ) cDNA ORF clone, Canis lupus familiaris(dog) -> NP_001003235.1 Canis lupus familiaris phosphodiesterase 6G (PDE6G), mRNA.

Price & Availability↑

CloneID	OCe00075
Clone ID Related Accession (Same CDS sequence)	XM_022422536.1 , XM_014116188.1 , NM_001003235.1
Accession Version	NM_001003235.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 264bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-25
Organism	Canis lupus familiaris(dog)
Product	retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from U49359.1. ##Evidence-Data-START## Transcript exon combination :: U49359.1, DN904453.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4547739 [ECO:0000348] ##Evidence-Data-END##

ATGAACCTGG AGCCACCGAA GGCCGAGATC CGGTCGGCCA CCAGGGTGAT TGGGGGGCCC 
GTCACTCCCA GAAAAGGGCC CCCCAAATTT AAGCAGCGGC AAACCAGGCA GTTCAAGAGC 
AAGCCCCCCA AGAAAGGCGT CCAAGGGTTT GGGGACGACA TCCCTGGAAT GGAAGGCCTG 
GGGACAGACA TCACGGTCAT CTGCCCTTGG GAGGCCTTCA ACCACCTGGA GCTGCACGAG 
CTGGCCCAGT ACGGCATCAT CTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001003235.1
CDS	170..433
Translation	MNLEPPKAEIRSATRVIGGPVTPRKGPPKFKQRQTRQFKSKPPKKGVQGFGDDIPGMEGLGTDITVICPWEAFNHLELHELAQYGII

Target ORF information:

RefSeq Version	NM_001003235.1
Organism	Canis lupus familiaris(dog)
Definition	Canis lupus familiaris phosphodiesterase 6G (PDE6G), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001003235.1

ORF Insert Sequence:

ATGAACCTGG AGCCACCGAA GGCCGAGATC CGGTCGGCCA CCAGGGTGAT TGGGGGGCCC 
GTCACTCCCA GAAAAGGGCC CCCCAAATTT AAGCAGCGGC AAACCAGGCA GTTCAAGAGC 
AAGCCCCCCA AGAAAGGCGT CCAAGGGTTT GGGGACGACA TCCCTGGAAT GGAAGGCCTG 
GGGACAGACA TCACGGTCAT CTGCCCTTGG GAGGCCTTCA ACCACCTGGA GCTGCACGAG 
CTGGCCCAGT ACGGCATCAT CTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PDE6G ( XM_022422536.1 ) cDNA ORF clone, Canis lupus familiaris(dog) -> XP_022278244.1 Canis lupus familiaris phosphodiesterase 6G (PDE6G), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OCe00075
Clone ID Related Accession (Same CDS sequence)	XM_022422536.1 , XM_014116188.1 , NM_001003235.1
Accession Version	XM_022422536.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 264bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-09-04
Organism	Canis lupus familiaris(dog)
Product	retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_006591.3) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Canis lupus familiaris Annotation Release 105 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAACCTGG AGCCACCGAA GGCCGAGATC CGGTCGGCCA CCAGGGTGAT TGGGGGGCCC 
GTCACTCCCA GAAAAGGGCC CCCCAAATTT AAGCAGCGGC AAACCAGGCA GTTCAAGAGC 
AAGCCCCCCA AGAAAGGCGT CCAAGGGTTT GGGGACGACA TCCCTGGAAT GGAAGGCCTG 
GGGACAGACA TCACGGTCAT CTGCCCTTGG GAGGCCTTCA ACCACCTGGA GCTGCACGAG 
CTGGCCCAGT ACGGCATCAT CTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_022278244.1
CDS	892..1155
Translation	MNLEPPKAEIRSATRVIGGPVTPRKGPPKFKQRQTRQFKSKPPKKGVQGFGDDIPGMEGLGTDITVICPWEAFNHLELHELAQYGII

Target ORF information:

RefSeq Version	XM_022422536.1
Organism	Canis lupus familiaris(dog)
Definition	Canis lupus familiaris phosphodiesterase 6G (PDE6G), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_022422536.1

ORF Insert Sequence:

ATGAACCTGG AGCCACCGAA GGCCGAGATC CGGTCGGCCA CCAGGGTGAT TGGGGGGCCC 
GTCACTCCCA GAAAAGGGCC CCCCAAATTT AAGCAGCGGC AAACCAGGCA GTTCAAGAGC 
AAGCCCCCCA AGAAAGGCGT CCAAGGGTTT GGGGACGACA TCCCTGGAAT GGAAGGCCTG 
GGGACAGACA TCACGGTCAT CTGCCCTTGG GAGGCCTTCA ACCACCTGGA GCTGCACGAG 
CTGGCCCAGT ACGGCATCAT CTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PDE6G ( XM_014116188.1 ) cDNA ORF clone, Canis lupus familiaris(dog) -> XP_013971663.1 Canis lupus familiaris phosphodiesterase 6G, cGMP-specific, rod, gamma (PDE6G), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OCe00075
Clone ID Related Accession (Same CDS sequence)	XM_022422536.1 , XM_014116188.1 , NM_001003235.1
Accession Version	XM_014116188.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 264bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-09-16
Organism	Canis lupus familiaris(Dog)
Product	retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma isoform X1
Comment	MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003726072.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Canis lupus familiaris Annotation Release 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAACCTGG AGCCACCGAA GGCCGAGATC CGGTCGGCCA CCAGGGTGAT TGGGGGGCCC 
GTCACTCCCA GAAAAGGGCC CCCCAAATTT AAGCAGCGGC AAACCAGGCA GTTCAAGAGC 
AAGCCCCCCA AGAAAGGCGT CCAAGGGTTT GGGGACGACA TCCCTGGAAT GGAAGGCCTG 
GGGACAGACA TCACGGTCAT CTGCCCTTGG GAGGCCTTCA ACCACCTGGA GCTGCACGAG 
CTGGCCCAGT ACGGCATCAT CTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_013971663.1
CDS	382..645
Translation	MNLEPPKAEIRSATRVIGGPVTPRKGPPKFKQRQTRQFKSKPPKKGVQGFGDDIPGMEGLGTDITVICPWEAFNHLELHELAQYGII

Target ORF information:

RefSeq Version	XM_014116188.1
Organism	Canis lupus familiaris(Dog)
Definition	Canis lupus familiaris phosphodiesterase 6G, cGMP-specific, rod, gamma (PDE6G), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_014116188.1

ORF Insert Sequence:

ATGAACCTGG AGCCACCGAA GGCCGAGATC CGGTCGGCCA CCAGGGTGAT TGGGGGGCCC 
GTCACTCCCA GAAAAGGGCC CCCCAAATTT AAGCAGCGGC AAACCAGGCA GTTCAAGAGC 
AAGCCCCCCA AGAAAGGCGT CCAAGGGTTT GGGGACGACA TCCCTGGAAT GGAAGGCCTG 
GGGACAGACA TCACGGTCAT CTGCCCTTGG GAGGCCTTCA ACCACCTGGA GCTGCACGAG 
CTGGCCCAGT ACGGCATCAT CTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Cloning of the cDNA encoding rod photoreceptor cGMP-phosphodiesterase alpha and gamma subunits from the retinal degenerate Labrador retriever dog.
Research in veterinary science62(3)293-6(1997 May-Jun)
Kylm? T,Paulin L,Hurwitz MY,Hurwitz RL,Kommonen B

Cloning and characterization of the cDNA and gene encoding the gamma-subunit of cGMP-phosphodiesterase in canine retinal rod photoreceptor cells.
Gene181(1-2)1-5(1996 Nov)
Wang W,Acland GM,Aguirre GD,Ray K

Elevation of cGMP with normal expression and activity of rod cGMP-PDE in photoreceptor degenerate labrador retrievers.
Ophthalmic research28(1)19-28(1996)
Kommonen B,Kylma T,Cohen RJ,Penn JS,Paulin L,Hurwitz M,Hurwitz RL