CCR5 cDNA ORF clone, Callithrix jacchus(white-tufted-ear marmoset)

Gene
Clones
gRNAs

Summary

Gene Symbol	CCR5
Entrez Gene ID	100399144
Full Name	C-C motif chemokine receptor 5
Gene Type	protein-coding
Organism	Callithrix jacchus(white-tufted-ear marmoset)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001257216.1	NP_001244145.1	C-C chemokine receptor type 5

Pathways from BioSystems
Gene Ontology
Bibliography

Related articles in PubMed

De novo assembly of the common marmoset transcriptome from NextGen mRNA sequences.
Maudhoo MD, Ren D, Gradnigo JS, Gibbs RM, Lubker AC, Moriyama EN, French JA, Norgren RB Jr
GigaScience314(2014)

CCR5 chemokine receptor gene evolution in New World monkeys (Platyrrhini, Primates): implication on resistance to lentiviruses.
Ribeiro IP, Schrago CG, Soares EA, Pissinatti A, Seuanez HN, Russo CA, Tanuri A, Soares MA
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases5(3)271-80(2005 Apr)

Blockade of HIV-1 infection of New World monkey cells occurs primarily at the stage of virus entry.
LaBonte JA, Babcock GJ, Patel T, Sodroski J
The Journal of experimental medicine196(4)431-45(2002 Aug)

Evolution of human and non-human primate CC chemokine receptor 5 gene and mRNA. Potential roles for haplotype and mRNA diversity, differential haplotype-specific transcriptional activity, and altered transcription factor binding to polymorphic nucleotides in the pathogenesis of HIV-1 and simian immunodeficiency virus.
Mummidi S, Bamshad M, Ahuja SS, Gonzalez E, Feuillet PM, Begum K, Galvis MC, Kostecki V, Valente AJ, Murthy KK, Haro L, Dolan MJ, Allan JS, Ahuja SK
The Journal of biological chemistry275(25)18946-61(2000 Jun)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following CCR5 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CCR5 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OCb21267	NM_001257216.1 Latest version!	Callithrix jacchus C-C motif chemokine receptor 5 (CCR5), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$258.30 $369.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

CCR5 ( NM_001257216.1 ) cDNA ORF clone, Callithrix jacchus(white-tufted-ear marmoset) -> NP_001244145.1 Callithrix jacchus C-C motif chemokine receptor 5 (CCR5), mRNA.

Price & Availability↑

CloneID	OCb21267
Clone ID Related Accession (Same CDS sequence)	NM_001257216.1
Accession Version	NM_001257216.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1059bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-06-25
Organism	Callithrix jacchus(white-tufted-ear marmoset)
Product	C-C chemokine receptor type 5
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AF452614.1 and ACFV01038714.1. On Mar 22, 2012 this sequence version replaced XM_002758281.1. ##Evidence-Data-START## Transcript is intronless :: AF452614.1 [ECO:0000345] ##Evidence-Data-END##

ATGGATTATC AAGTGTCAAG TCCAATCTAT GACATCGATT ATGGCCCATC GGAGCCCTGC 
CGAAAAATCG ACGTGAAGCA AATGGGAGCC CACCTCCTGC CTCCGCTCTA CTCCATGGTG 
TTCCTCTTTG GTTTCGTGGG CAACATGCTG GTTGTCCTCA TTCTGATAAA CTGCAAAAGG 
CTGAAGAGTA TGACTGACAT CTACCTGCTC AACCTGGCCA TCTCTGACCT GATTTTCCTT 
TTTACTGTCC CCTTCTGGGC TCACTATGCT GCAGGCCAGT GGGACTTCGG AAATACAATG 
TGTCAGTTCT TGACAGGGCT CTATTTTATA GGCTTCTTCT CTGGAATCTT CTTCATCATC 
CTCCTGACAA TCGATAGGTA CCTGGCTATC GTCCATGCTG TGTTTGCTTT AAAAGCCAGG 
ACGGTCACCT TTGGGGTGGT GACAAGTGTG ATCACTTGGG TGGTGGCTGT ATTTGCCTCT 
CTCCCAGGAA TCATCTTTAC CAGGTCTCAA AAAGAAGGTT ATCATTACAC CTGCAGCCCT 
CATTTTCCAT TCAGCCAATA TCAGTTCTGG AAGAATTTCG AGACATTAAA GATGGTCATC 
TTGGGGCTGG TCCTGCCACT GCTCGTCATG GTCATCTGCT ACTCGGGAAT CCTTAAAACC 
CTGCTTCGGT GTCGAAATGA GAAGAAGAGG CACAGGGCTG TGAGGCTTAT CTTCACCATC 
ATGATTGTTT ATTTTCTCTT CTGGGCTCCC TACAACATTG TCCTTCTCCT GAACACCTAC 
CAGGAATTCT TTGGCCTGAA TAATTGCAGT AGCTCTAACA GGTTGGACCA AGCCATGCAA 
GTGACAGAGA CTCTTGGGAT GACACATTGC TGCGTCAACC CCATCATCTA TGCTTTTGTC 
GGGGAGAAGT TTAGAAACTA CCTCGCGGTC TTCTTCCAAA AGCACATTGC CAAGTGCTTC 
TGTGAATGCT GTTCCATCTT CCAGAAAGAG GCTCCCGAGC GAGCAAACTC AGTTTATACT 
CGATCCACCG GGGAGCAGGA AATATCTGTG GGCTTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001244145.1
CDS	1..1059
Translation	MDYQVSSPIYDIDYGPSEPCRKIDVKQMGAHLLPPLYSMVFLFGFVGNMLVVLILINCKRLKSMTDIYLLNLAISDLIFLFTVPFWAHYAAGQWDFGNTMCQFLTGLYFIGFFSGIFFIILLTIDRYLAIVHAVFALKARTVTFGVVTSVITWVVAVFASLPGIIFTRSQKEGYHYTCSPHFPFSQYQFWKNFETLKMVILGLVLPLLVMVICYSGILKTLLRCRNEKKRHRAVRLIFTIMIVYFLFWAPYNIVLLLNTYQEFFGLNNCSSSNRLDQAMQVTETLGMTHCCVNPIIYAFVGEKFRNYLAVFFQKHIAKCFCECCSIFQKEAPERANSVYTRSTGEQEISVGL

Target ORF information:

RefSeq Version	NM_001257216.1
Organism	Callithrix jacchus(white-tufted-ear marmoset)
Definition	Callithrix jacchus C-C motif chemokine receptor 5 (CCR5), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001257216.1

ORF Insert Sequence:

ATGGATTATC AAGTGTCAAG TCCAATCTAT GACATCGATT ATGGCCCATC GGAGCCCTGC 
CGAAAAATCG ACGTGAAGCA AATGGGAGCC CACCTCCTGC CTCCGCTCTA CTCCATGGTG 
TTCCTCTTTG GTTTCGTGGG CAACATGCTG GTTGTCCTCA TTCTGATAAA CTGCAAAAGG 
CTGAAGAGTA TGACTGACAT CTACCTGCTC AACCTGGCCA TCTCTGACCT GATTTTCCTT 
TTTACTGTCC CCTTCTGGGC TCACTATGCT GCAGGCCAGT GGGACTTCGG AAATACAATG 
TGTCAGTTCT TGACAGGGCT CTATTTTATA GGCTTCTTCT CTGGAATCTT CTTCATCATC 
CTCCTGACAA TCGATAGGTA CCTGGCTATC GTCCATGCTG TGTTTGCTTT AAAAGCCAGG 
ACGGTCACCT TTGGGGTGGT GACAAGTGTG ATCACTTGGG TGGTGGCTGT ATTTGCCTCT 
CTCCCAGGAA TCATCTTTAC CAGGTCTCAA AAAGAAGGTT ATCATTACAC CTGCAGCCCT 
CATTTTCCAT TCAGCCAATA TCAGTTCTGG AAGAATTTCG AGACATTAAA GATGGTCATC 
TTGGGGCTGG TCCTGCCACT GCTCGTCATG GTCATCTGCT ACTCGGGAAT CCTTAAAACC 
CTGCTTCGGT GTCGAAATGA GAAGAAGAGG CACAGGGCTG TGAGGCTTAT CTTCACCATC 
ATGATTGTTT ATTTTCTCTT CTGGGCTCCC TACAACATTG TCCTTCTCCT GAACACCTAC 
CAGGAATTCT TTGGCCTGAA TAATTGCAGT AGCTCTAACA GGTTGGACCA AGCCATGCAA 
GTGACAGAGA CTCTTGGGAT GACACATTGC TGCGTCAACC CCATCATCTA TGCTTTTGTC 
GGGGAGAAGT TTAGAAACTA CCTCGCGGTC TTCTTCCAAA AGCACATTGC CAAGTGCTTC 
TGTGAATGCT GTTCCATCTT CCAGAAAGAG GCTCCCGAGC GAGCAAACTC AGTTTATACT 
CGATCCACCG GGGAGCAGGA AATATCTGTG GGCTTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

De novo assembly of the common marmoset transcriptome from NextGen mRNA sequences.
GigaScience314(2014)
Maudhoo MD,Ren D,Gradnigo JS,Gibbs RM,Lubker AC,Moriyama EN,French JA,Norgren RB Jr

CCR5 chemokine receptor gene evolution in New World monkeys (Platyrrhini, Primates): implication on resistance to lentiviruses.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases5(3)271-80(2005 Apr)
Ribeiro IP,Schrago CG,Soares EA,Pissinatti A,Seuanez HN,Russo CA,Tanuri A,Soares MA

Blockade of HIV-1 infection of New World monkey cells occurs primarily at the stage of virus entry.
The Journal of experimental medicine196(4)431-45(2002 Aug)
LaBonte JA,Babcock GJ,Patel T,Sodroski J

Evolution of human and non-human primate CC chemokine receptor 5 gene and mRNA. Potential roles for haplotype and mRNA diversity, differential haplotype-specific transcriptional activity, and altered transcription factor binding to polymorphic nucleotides in the pathogenesis of HIV-1 and simian immunodeficiency virus.
The Journal of biological chemistry275(25)18946-61(2000 Jun)
Mummidi S,Bamshad M,Ahuja SS,Gonzalez E,Feuillet PM,Begum K,Galvis MC,Kostecki V,Valente AJ,Murthy KK,Haro L,Dolan MJ,Allan JS,Ahuja SK