| Gene Symbol | top-1 |
| Entrez Gene ID | 266847 |
| Full Name | DNA topoisomerase 1 |
| Gene Type | protein-coding |
| Organism | Caenorhabditis elegans |
ORF » Species Summary » Caenorhabditis elegans » top-1 cDNA ORF clone
| Gene Symbol | top-1 |
| Entrez Gene ID | 266847 |
| Full Name | DNA topoisomerase 1 |
| Gene Type | protein-coding |
| Organism | Caenorhabditis elegans |
| mRNA | Protein | Name |
|---|---|---|
| NM_001026407.5 | NP_001021578.1 | DNA topoisomerase 1 |
| NM_060936.6 | NP_493337.1 | DNA topoisomerase 1 |
| NM_001026407.6 | NP_001021578.1 | DNA topoisomerase 1 |
| NM_060936.5 | NP_493337.1 | DNA topoisomerase 1 |
| TOP1 | XP_001088021.1 | |
| Bos taurus (cattle) | TOP1 | NP_001193416.1 |
| Gallus gallus (chicken) | TOP1 | NP_990441.1 |
| Neurospora crassa | NCU09118 | XP_958033.2 |
| Arabidopsis thaliana (thale cress) | TOP1ALPHA | NP_200341.1 |
| Canis lupus familiaris (dog) | TOP1 | XP_534420.3 |
| Caenorhabditis elegans (roundworm) | top-1 | NP_001021578.1 |
| Saccharomyces cerevisiae (baker's yeast) | TOP1 | NP_014637.1 |
| Magnaporthe oryzae (rice blast fungus) | MGG_09917 | XP_003710015.1 |
| Arabidopsis thaliana (thale cress) | TOP1BETA | NP_200342.1 |
| Kluyveromyces lactis | KLLA0C06116g | XP_452470.1 |
| Eremothecium gossypii | AGOS_ACL008C | NP_983396.2 |
| Xenopus tropicalis (tropical clawed frog) | LOC100496521 | XP_002932918.2 |
| Mus musculus (house mouse) | Top1 | NP_033434.2 |
| Danio rerio (zebrafish) | top1l | NP_001037789.1 |
| Oryza sativa (rice) | Os08g0154600 | NP_001061015.1 |
| Homo sapiens (human) | TOP1 | NP_003277.1 |
| Pan troglodytes (chimpanzee) | TOP1 | XP_514649.2 |
| Rattus norvegicus (Norway rat) | Top1 | NP_072137.1 |
| Drosophila melanogaster (fruit fly) | Top1 | NP_001014742.1 |
| Anopheles gambiae (African malaria mosquito) | AgaP_AGAP004078 | XP_003436707.1 |
| Schizosaccharomyces pombe (fission yeast) | top1 | NP_596209.1 |
Genome sequence of the nematode C. elegans: a platform for investigating biology.
Science (New York, N.Y.)282(5396)2012-8(1998 Dec)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
While TOP-1alpha isoform has tissue specificity, the TOP-1beta isoform is expressed in most tissues and cells. RNAi targeted to both TOP-1 isoforms demonstrated that TOP-1 is required for chromosomal segregation, germline proliferation and gonadal migration.
Title: Differential subcellular localization of DNA topoisomerase-1 isoforms and their roles during Caenorhabditis elegans development.
The following top-1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the top-1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | OCa335871 | |
| Clone ID Related Accession (Same CDS sequence) | NM_001026407.5 , NM_001026407.6 | |
| Accession Version | NM_001026407.5 | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 2205bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-04-08 | |
| Organism | Caenorhabditis elegans | |
| Product | DNA topoisomerase 1 | |
| Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003279). On Jun 26, 2012 this sequence version replaced NM_001026407.4. COMPLETENESS: incomplete on both ends. | |
1 | ATGAGTGTAG TGTCGAATCA TCACTCGAAC GGAAACGGCA ACTCAACAGT CTACGATACG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_001021578.1 |
| CDS | 1..2205 |
| Translation |
Target ORF information:
Target ORF information:
|
NM_001026407.5 |
1 | ATGAGTGTAG TGTCGAATCA TCACTCGAAC GGAAACGGCA ACTCAACAGT CTACGATACG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OCa335871 | |
| Clone ID Related Accession (Same CDS sequence) | NM_001026407.5 , NM_001026407.6 | |
| Accession Version | NM_001026407.6 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 2205bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-10-17 | |
| Organism | Caenorhabditis elegans | |
| Product | DNA topoisomerase 1 | |
| Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003279). On Sep 4, 2019 this sequence version replaced NM_001026407.5. | |
1 | ATGAGTGTAG TGTCGAATCA TCACTCGAAC GGAAACGGCA ACTCAACAGT CTACGATACG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_001021578.1 |
| CDS | 113..2317 |
| Translation |
Target ORF information:
Target ORF information:
|
NM_001026407.6 |
1 | ATGAGTGTAG TGTCGAATCA TCACTCGAAC GGAAACGGCA ACTCAACAGT CTACGATACG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OCa335872 | |
| Clone ID Related Accession (Same CDS sequence) | NM_060936.6 , NM_060936.5 | |
| Accession Version | NM_060936.6 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 2421bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-10-17 | |
| Organism | Caenorhabditis elegans | |
| Product | DNA topoisomerase 1 | |
| Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003279). On Sep 4, 2019 this sequence version replaced NM_060936.5. | |
1 | ATGAGTGTAG TGTCGAATCA TCACTCGAAC GGAAACGGCA ACTCAACAGT CTACGATACG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_493337.1 |
| CDS | 113..2533 |
| Translation |
Target ORF information:
Target ORF information:
|
NM_060936.6 |
1 | ATGAGTGTAG TGTCGAATCA TCACTCGAAC GGAAACGGCA ACTCAACAGT CTACGATACG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OCa335872 | |
| Clone ID Related Accession (Same CDS sequence) | NM_060936.6 , NM_060936.5 | |
| Accession Version | NM_060936.5 | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 2421bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-04-08 | |
| Organism | Caenorhabditis elegans | |
| Product | DNA topoisomerase 1 | |
| Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003279). On Jun 26, 2012 this sequence version replaced NM_060936.4. COMPLETENESS: incomplete on both ends. | |
1 | ATGAGTGTAG TGTCGAATCA TCACTCGAAC GGAAACGGCA ACTCAACAGT CTACGATACG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_493337.1 |
| CDS | 1..2421 |
| Translation |
Target ORF information:
Target ORF information:
|
NM_060936.5 |
1 | ATGAGTGTAG TGTCGAATCA TCACTCGAAC GGAAACGGCA ACTCAACAGT CTACGATACG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Genome sequence of the nematode C. elegans: a platform for investigating biology. |