| Gene Symbol | dat-1 |
| Entrez Gene ID | 176304 |
| Full Name | Sodium-dependent dopamine transporter |
| Gene Type | protein-coding |
| Organism | Caenorhabditis elegans |
ORF » Species Summary » Caenorhabditis elegans » dat-1 cDNA ORF clone
| Gene Symbol | dat-1 |
| Entrez Gene ID | 176304 |
| Full Name | Sodium-dependent dopamine transporter |
| Gene Type | protein-coding |
| Organism | Caenorhabditis elegans |
| mRNA | Protein | Name |
|---|---|---|
| NM_066642.5 | NP_499043.1 | Sodium-dependent dopamine transporter |
| NM_066642.6 | NP_499043.1 | Sodium-dependent dopamine transporter |
| Mus musculus (house mouse) | Slc6a2 | NP_033235.3 |
| Gallus gallus (chicken) | SLC6A2 | NP_990047.1 |
| Caenorhabditis elegans (roundworm) | dat-1 | NP_499043.1 |
| SLC6A2 | NP_001028195.1 | |
| Rattus norvegicus (Norway rat) | Slc6a2 | NP_112633.1 |
| Anopheles gambiae (African malaria mosquito) | AgaP_AGAP007367 | XP_308462.4 |
| Homo sapiens (human) | SLC6A2 | NP_001165972.1 |
| Drosophila melanogaster (fruit fly) | DAT | NP_523763.2 |
| Pan troglodytes (chimpanzee) | SLC6A2 | XP_001167725.1 |
| Bos taurus (cattle) | SLC6A2 | NP_777033.1 |
| Canis lupus familiaris (dog) | SLC6A2 | NP_001129974.1 |
| Danio rerio (zebrafish) | LOC565776 | XP_694138.3 |
| Xenopus tropicalis (tropical clawed frog) | slc6a2 | XP_002939272.2 |
Genome sequence of the nematode C. elegans: a platform for investigating biology.
Science (New York, N.Y.)282(5396)2012-8(1998 Dec)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
loss of UNC-64/DAT-1 interactions leads to enhanced synaptic dopamine release
Title: Dopamine transporter/syntaxin 1A interactions regulate transporter channel activity and dopaminergic synaptic transmission.
Endogenous dopamine actions in C. elegans are tightly regulated by synaptic DAT-1.
Title: Vigorous motor activity in Caenorhabditis elegans requires efficient clearance of dopamine mediated by synaptic localization of the dopamine transporter DAT-1.
T23G5.5-transfected HeLa transports dopamine. Weaker activity for other biogenic amines (tyramine, octopamine, serotonin, norepinephrine). Inhibitors include the tricyclics imipramine and desipramine, cocaine, nomifensine, nisoxetine, and D-amphetamine.
Title: The Caenorhabditis elegans gene T23G5.5 encodes an antidepressant- and cocaine-sensitive dopamine transporter.
The following dat-1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the dat-1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | OCa340080 | |
| Clone ID Related Accession (Same CDS sequence) | NM_066642.5 , NM_066642.6 | |
| Accession Version | NM_066642.5 | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 1848bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-04-08 | |
| Organism | Caenorhabditis elegans | |
| Product | Sodium-dependent dopamine transporter | |
| Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003281). On Jun 26, 2012 this sequence version replaced NM_066642.4. COMPLETENESS: incomplete on both ends. | |
1 | ATGCAGTTGG TGCCTACAGA CGATCCCGAC GAAAAAATCG GTCGGACGTC TAATGGCATG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_499043.1 |
| CDS | 1..1848 |
| Translation |
Target ORF information:
Target ORF information:
|
NM_066642.5 |
1 | ATGCAGTTGG TGCCTACAGA CGATCCCGAC GAAAAAATCG GTCGGACGTC TAATGGCATG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OCa340080 | |
| Clone ID Related Accession (Same CDS sequence) | NM_066642.5 , NM_066642.6 | |
| Accession Version | NM_066642.6 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 1848bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-10-17 | |
| Organism | Caenorhabditis elegans | |
| Product | Sodium-dependent dopamine transporter | |
| Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003281). On Sep 4, 2019 this sequence version replaced NM_066642.5. | |
1 | ATGCAGTTGG TGCCTACAGA CGATCCCGAC GAAAAAATCG GTCGGACGTC TAATGGCATG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_499043.1 |
| CDS | 62..1909 |
| Translation |
Target ORF information:
Target ORF information:
|
NM_066642.6 |
1 | ATGCAGTTGG TGCCTACAGA CGATCCCGAC GAAAAAATCG GTCGGACGTC TAATGGCATG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Genome sequence of the nematode C. elegans: a platform for investigating biology. |