| Gene Symbol | mtcu-2 |
| Entrez Gene ID | 174563 |
| Full Name | Protein MTO1 homolog, mitochondrial |
| Gene Type | protein-coding |
| Organism | Caenorhabditis elegans |
ORF » Species Summary » Caenorhabditis elegans » mtcu-2 cDNA ORF clone
| Gene Symbol | mtcu-2 |
| Entrez Gene ID | 174563 |
| Full Name | Protein MTO1 homolog, mitochondrial |
| Gene Type | protein-coding |
| Organism | Caenorhabditis elegans |
| mRNA | Protein | Name |
|---|---|---|
| NM_063768.5 | NP_496169.1 | Protein MTO1 homolog, mitochondrial |
| NM_063768.6 | NP_496169.1 | Protein MTO1 homolog, mitochondrial |
| Canis lupus familiaris (dog) | MTO1 | XP_532202.3 |
| Anopheles gambiae (African malaria mosquito) | AgaP_AGAP007661 | XP_308209.4 |
| Magnaporthe oryzae (rice blast fungus) | MGG_14754 | XP_003713873.1 |
| Danio rerio (zebrafish) | mto1 | NP_001076478.1 |
| Caenorhabditis elegans (roundworm) | F52H3.2 | NP_496169.1 |
| Eremothecium gossypii | AGOS_AFR255W | NP_985802.2 |
| Oryza sativa (rice) | Os01g0960300 | NP_001045465.1 |
| Homo sapiens (human) | MTO1 | NP_001116698.1 |
| Pan troglodytes (chimpanzee) | MTO1 | XP_003311451.1 |
| Saccharomyces cerevisiae (baker's yeast) | MTO1 | NP_011278.2 |
| Kluyveromyces lactis | KLLA0A00935g | XP_451040.1 |
| Schizosaccharomyces pombe (fission yeast) | SPBC30B4.06c | NP_595531.1 |
| Neurospora crassa | NCU11170 | XP_956189.2 |
| Bos taurus (cattle) | MTO1 | NP_001069537.1 |
| Mus musculus (house mouse) | Mto1 | NP_080934.2 |
| Rattus norvegicus (Norway rat) | Mto1 | NP_001100311.1 |
| Gallus gallus (chicken) | MTO1 | NP_001073232.1 |
| Drosophila melanogaster (fruit fly) | CG4610 | NP_611677.1 |
| Arabidopsis thaliana (thale cress) | AT2G13440 | NP_178974.1 |
Genome sequence of the nematode C. elegans: a platform for investigating biology.
Science (New York, N.Y.)282(5396)2012-8(1998 Dec)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
We further show that mtcu-1; mttu-1 and mtcu-2; mttu-1 double mutants display severe growth defects and sterility. The animal models presented here support the idea that the pathological states in humans may initially develop not as a direct consequence of a bioenergetic defect, but from the cell's maladaptive response to the hypomodification status of mt-tRNAs
Title: Mutations in the Caenorhabditis elegans orthologs of human genes required for mitochondrial tRNA modification cause similar electron transport chain defects but different nuclear responses.
The following mtcu-2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the mtcu-2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | OCa339802 | |
| Clone ID Related Accession (Same CDS sequence) | NM_063768.5 , NM_063768.6 | |
| Accession Version | NM_063768.5 | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 1917bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-04-08 | |
| Organism | Caenorhabditis elegans | |
| Product | Protein MTO1 homolog, mitochondrial | |
| Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003280). On Jun 26, 2012 this sequence version replaced NM_063768.4. COMPLETENESS: incomplete on both ends. | |
1 | ATGTTAAGCA AAAGCACTCG ATTATTGCGA CGATGTTTTC AAACAGATGT TGATGTGATT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_496169.1 |
| CDS | 1..1917 |
| Translation |
Target ORF information:
Target ORF information:
|
NM_063768.5 |
1 | ATGTTAAGCA AAAGCACTCG ATTATTGCGA CGATGTTTTC AAACAGATGT TGATGTGATT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OCa339802 | |
| Clone ID Related Accession (Same CDS sequence) | NM_063768.5 , NM_063768.6 | |
| Accession Version | NM_063768.6 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 1917bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-10-17 | |
| Organism | Caenorhabditis elegans | |
| Product | Protein MTO1 homolog, mitochondrial | |
| Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003280). On Sep 4, 2019 this sequence version replaced NM_063768.5. | |
1 | ATGTTAAGCA AAAGCACTCG ATTATTGCGA CGATGTTTTC AAACAGATGT TGATGTGATT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_496169.1 |
| CDS | 6..1922 |
| Translation |
Target ORF information:
Target ORF information:
|
NM_063768.6 |
1 | ATGTTAAGCA AAAGCACTCG ATTATTGCGA CGATGTTTTC AAACAGATGT TGATGTGATT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Genome sequence of the nematode C. elegans: a platform for investigating biology. |