POMC cDNA ORF clone, Bos taurus(cattle)

Gene
Clones
gRNAs

Summary

Gene Symbol	POMC
Entrez Gene ID	281416
Full Name	proopiomelanocortin
General protein information	Preferred Names proopiomelanocortin Names pro-opiomelanocortin adrenocorticotropin alpha-melanocyte stimulating hormone beta-endorphin beta-lipotropin beta-melanocyte stimulating hormone corticotropin-lipotropin proopiomelanocortin (adrenocorticotropin/ beta-lipotropin/ alpha-melanocyte stimulating hormone/ beta-melanocyte stimulating hormone/ beta-endorphin)
Gene Type	protein-coding
Organism	Bos taurus(cattle)

mRNA and Protein(s)

mRNA	Protein	Name
XM_005212920.2	XP_005212977.1	pro-opiomelanocortin isoform X2
XM_010810166.2	XP_010808468.1	pro-opiomelanocortin isoform X1
NM_174151.1	NP_776576.1	pro-opiomelanocortin precursor
XM_010810166.1	XP_010808468.1	pro-opiomelanocortin isoform X1

Pathways from BioSystems

Homologies

Homo sapiens (human)	POMC	NP_000930.1
Mus musculus (house mouse)	Pomc	NP_001265512.1
Rattus norvegicus (Norway rat)	Pomc	NP_647542.1
Danio rerio (zebrafish)	pomca	NP_852103.1
	POMC	XP_001082999.1
Canis lupus familiaris (dog)	POMC	XP_849463.3
Xenopus tropicalis (tropical clawed frog)	pomc	NP_001011318.1
Pan troglodytes (chimpanzee)	POMC	XP_003309010.1
Bos taurus (cattle)	POMC	NP_776576.1
Gallus gallus (chicken)	POMC	NP_001026269.1

Gene Ontology
Bibliography

Related articles in PubMed

Pituitary genomic expression profiles of steers are altered by grazing of high vs. low endophyte-infected tall fescue forages.
Li Q, Hegge R, Bridges PJ, Matthews JC
PloS one12(9)e0184612(2017)

Association between polymorphisms of the CRH and POMC genes with economic traits in Korean cattle (Hanwoo).
Seong J, Kong HS
Genetics and molecular research : GMR14(3)10415-21(2015 Sep)

Endocannabinoid system and proopiomelanocortin gene expression in peripartal bovine liver in response to prepartal plane of nutrition.
Khan MJ, Graugnard DE, Loor JJ
Journal of animal physiology and animal nutrition96(5)907-19(2012 Oct)

Characterization of two pro-opiomelanocortin gene variants and their effects on carcass traits in beef cattle.
Deobald HM, Buchanan FC
BMC genetics122(2011 Jan)

[The polymorphism of bovine POMC gene and its association with the growth traits of Nanyang cattle].
Zhang CL, Wang YH, Chen H, Lei CZ, Fang XT, Wang JQ, Ma GB, Niu H, Xiao J
Yi chuan = Hereditas31(12)1221-5(2009 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The association has been reported between polymorphisms of the CRH and POMC genes with economic traits in Korean cattle.
Title: Association between polymorphisms of the CRH and POMC genes with economic traits in Korean cattle (Hanwoo).

Expression of the hepatic endocannabinoid system and proopiomelanocortin was altered by plane of dietary energy prepartum particularly during the first 2-week postpartum.
Title: Endocannabinoid system and proopiomelanocortin gene expression in peripartal bovine liver in response to prepartal plane of nutrition.

Significant associations were observed between POMC c.288C>T with start-of-finishing weight (SOF WT; P = 0.04), hot carcass weight (HCW; P = 0.02), average fat and grade fat (both P = 0.05), carcass rib-eye area (REA; P = 0.03) and marbling
Title: Characterization of two pro-opiomelanocortin gene variants and their effects on carcass traits in beef cattle.

The polymorphism of POMC gene is associated with the growth traits of Nanyang cattle.
Title: [The polymorphism of bovine POMC gene and its association with the growth traits of Nanyang cattle].

The following POMC gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the POMC cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OBa41709	NM_174151.1 Latest version!	Bos taurus proopiomelanocortin (POMC), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$174.30 $249.00
OBa24144	XM_005212920.2 Latest version!	Bos taurus proopiomelanocortin (POMC), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$174.30 $249.00
OBa45136	XM_010810166.2 Latest version!	Bos taurus proopiomelanocortin (POMC), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$174.30 $249.00
View Old Accession Versions >>
OBa45136	XM_010810166.1	Bos taurus proopiomelanocortin (POMC), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$174.30 $249.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

POMC ( NM_174151.1 ) cDNA ORF clone, Bos taurus(cattle) -> NP_776576.1 Bos taurus proopiomelanocortin (POMC), mRNA.

Price & Availability↑

CloneID	OBa41709
Clone ID Related Accession (Same CDS sequence)	NM_174151.1
Accession Version	NM_174151.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 798bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-19
Organism	Bos taurus(cattle)
Product	pro-opiomelanocortin precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from M25587.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: M25587.1, CO879715.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN03145419, SAMN03145429 [ECO:0000348] ##Evidence-Data-END##

ATGCCGAGAC TGTGCAGCAG TCGTTCGGCC GCCCTGCTGC TGGCCTTGCT GCTTCAGGCC 
TCCATGGAAG TGCGTGGTTG GTGCCTGGAG AGCAGCCAGT GTCAGGACCT CACCACGGAA 
AGTAACCTGC TGGCGTGCAT CCGGGCCTGC AAGCCCGACC TCTCCGCCGA GACGCCGGTG 
TTCCCCGGCA ACGGCGATGA GCAGCCGCTG ACTGAGAACC CCCGGAAGTA CGTCATGGGC 
CATTTCCGCT GGGACCGCTT CGGCCGTCGG AATGGTAGCA GCAGCAGCGG AGTTGGGGGC 
GCGGCCCAGA AGCGCGAGGA GGAAGTGGCG GTGGGCGAAG GCCCCGGGCC CCGCGGCGAT 
GACGCCGAGA CGGGTCCGCG CGAGGACAAG CGTTCTTACT CCATGGAACA CTTCCCCTGG 
GGCAAGCCGG TGGGCAAGAA GCGGCGCCCG GTGAAGGTGT ACCCCAACGG CGCCGAGGAC 
GAGTCGGCCC AGGCCTTTCC CCTCGAATTC AAGAGGGAGC TGACCGGGGA GAGGCTCGAG 
CAGGCGCGCG GCCCCGAGGC CCAGGCTGAG AGTGCGGCCG CCCGGCCTGA GCTGGAGTAT 
GGCCTGGTGG CGGAGGCGGA GGCTGAGGCG GCCGAGAAGA AGGACTCGGG GCCCTATAAG 
ATGGAACACT TCCGCTGGGG CAGCCCGCCC AAGGACAAGC GCTACGGCGG GTTCATGACC 
TCCGAGAAGA GCCAAACGCC CCTTGTCACG CTGTTCAAAA ACGCCATCAT CAAGAACGCC 
CACAAGAAGG GCCAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_776576.1
CDS	114..911
Translation	MPRLCSSRSAALLLALLLQASMEVRGWCLESSQCQDLTTESNLLACIRACKPDLSAETPVFPGNGDEQPLTENPRKYVMGHFRWDRFGRRNGSSSSGVGGAAQKREEEVAVGEGPGPRGDDAETGPREDKRSYSMEHFPWGKPVGKKRRPVKVYPNGAEDESAQAFPLEFKRELTGERLEQARGPEAQAESAAARPELEYGLVAEAEAEAAEKKDSGPYKMEHFRWGSPPKDKRYGGFMTSEKSQTPLVTLFKNAIIKNAHKKGQ

Target ORF information:

RefSeq Version	NM_174151.1
Organism	Bos taurus(cattle)
Definition	Bos taurus proopiomelanocortin (POMC), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_174151.1

ORF Insert Sequence:

ATGCCGAGAC TGTGCAGCAG TCGTTCGGCC GCCCTGCTGC TGGCCTTGCT GCTTCAGGCC 
TCCATGGAAG TGCGTGGTTG GTGCCTGGAG AGCAGCCAGT GTCAGGACCT CACCACGGAA 
AGTAACCTGC TGGCGTGCAT CCGGGCCTGC AAGCCCGACC TCTCCGCCGA GACGCCGGTG 
TTCCCCGGCA ACGGCGATGA GCAGCCGCTG ACTGAGAACC CCCGGAAGTA CGTCATGGGC 
CATTTCCGCT GGGACCGCTT CGGCCGTCGG AATGGTAGCA GCAGCAGCGG AGTTGGGGGC 
GCGGCCCAGA AGCGCGAGGA GGAAGTGGCG GTGGGCGAAG GCCCCGGGCC CCGCGGCGAT 
GACGCCGAGA CGGGTCCGCG CGAGGACAAG CGTTCTTACT CCATGGAACA CTTCCCCTGG 
GGCAAGCCGG TGGGCAAGAA GCGGCGCCCG GTGAAGGTGT ACCCCAACGG CGCCGAGGAC 
GAGTCGGCCC AGGCCTTTCC CCTCGAATTC AAGAGGGAGC TGACCGGGGA GAGGCTCGAG 
CAGGCGCGCG GCCCCGAGGC CCAGGCTGAG AGTGCGGCCG CCCGGCCTGA GCTGGAGTAT 
GGCCTGGTGG CGGAGGCGGA GGCTGAGGCG GCCGAGAAGA AGGACTCGGG GCCCTATAAG 
ATGGAACACT TCCGCTGGGG CAGCCCGCCC AAGGACAAGC GCTACGGCGG GTTCATGACC 
TCCGAGAAGA GCCAAACGCC CCTTGTCACG CTGTTCAAAA ACGCCATCAT CAAGAACGCC 
CACAAGAAGG GCCAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

POMC ( XM_005212920.2 ) cDNA ORF clone, Bos taurus(cattle) -> XP_005212977.1 Bos taurus proopiomelanocortin (POMC), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OBa24144
Clone ID Related Accession (Same CDS sequence)	XM_005212920.2
Accession Version	XM_005212920.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 798bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-05-06
Organism	Bos taurus(cattle)
Product	pro-opiomelanocortin isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_037338.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Dec 30, 2014 this sequence version replaced XM_005212920.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Bos taurus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCCGAGAC TGTGCAGCAG TCGTTCGGGC GCCCTGCTGC TGGCCTTGCT GCTTCAGGCC 
TCCATGGAAG TGCGTGGTTG GTGCCTGGAG AGCAGCCAGT GTCAGGACCT CACCACGGAA 
AGTAACCTGC TGGCGTGCAT CCGGGCCTGC AAGCCCGACC TCTCCGCCGA GACGCCGGTG 
TTCCCCGGCA ACGGCGATGA GCAGCCGCTG ACTGAGAACC CCCGGAAGTA CGTCATGGGC 
CATTTCCGCT GGGACCGCTT CGGCCGTCGG AATGGTAGCA GCAGCAGCGG AGTTGGGGGC 
GCGGCCCAGA AGCGCGAGGA GGAAGTGGCG GTGGGCGAAG GCCCCGGGCC CCGCGGCGAT 
GACGCCGAGA CGGGTCCGCG CGAGGACAAG CGTTCTTACT CCATGGAACA CTTCCGCTGG 
GGCAAGCCGG TGGGCAAGAA GCGGCGCCCG GTGAAGGTGT ACCCCAACGG CGCCGAGGAC 
GAGTCGGCCC AGGCCTTTCC CCTCGAATTC AAGAGGGAGC TGACCGGGGA GAGGCTCGAG 
CAGGCGCGCG GCCCCGAGGC CCAGGCTGAG AGTGCGGCCG CCCGGGCTGA GCTGGAGTAT 
GGCCTGGTGG CGGAGGCGGA GGCTGAGGCG GCCGAGAAGA AGGACTCGGG GCCCTATAAG 
ATGGAACACT TCCGCTGGGG CAGCCCGCCC AAGGACAAGC GCTACGGCGG GTTCATGACC 
TCCGAGAAGA GCCAAACGCC CCTTGTCACG CTGTTCAAAA ACGCCATCAT CAAGAACGCC 
CACAAGAAGG GCCAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005212977.1
CDS	287..1084
Translation	MPRLCSSRSGALLLALLLQASMEVRGWCLESSQCQDLTTESNLLACIRACKPDLSAETPVFPGNGDEQPLTENPRKYVMGHFRWDRFGRRNGSSSSGVGGAAQKREEEVAVGEGPGPRGDDAETGPREDKRSYSMEHFRWGKPVGKKRRPVKVYPNGAEDESAQAFPLEFKRELTGERLEQARGPEAQAESAAARAELEYGLVAEAEAEAAEKKDSGPYKMEHFRWGSPPKDKRYGGFMTSEKSQTPLVTLFKNAIIKNAHKKGQ

Target ORF information:

RefSeq Version	XM_005212920.2
Organism	Bos taurus(cattle)
Definition	Bos taurus proopiomelanocortin (POMC), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005212920.2

ORF Insert Sequence:

ATGCCGAGAC TGTGCAGCAG TCGTTCGGGC GCCCTGCTGC TGGCCTTGCT GCTTCAGGCC 
TCCATGGAAG TGCGTGGTTG GTGCCTGGAG AGCAGCCAGT GTCAGGACCT CACCACGGAA 
AGTAACCTGC TGGCGTGCAT CCGGGCCTGC AAGCCCGACC TCTCCGCCGA GACGCCGGTG 
TTCCCCGGCA ACGGCGATGA GCAGCCGCTG ACTGAGAACC CCCGGAAGTA CGTCATGGGC 
CATTTCCGCT GGGACCGCTT CGGCCGTCGG AATGGTAGCA GCAGCAGCGG AGTTGGGGGC 
GCGGCCCAGA AGCGCGAGGA GGAAGTGGCG GTGGGCGAAG GCCCCGGGCC CCGCGGCGAT 
GACGCCGAGA CGGGTCCGCG CGAGGACAAG CGTTCTTACT CCATGGAACA CTTCCGCTGG 
GGCAAGCCGG TGGGCAAGAA GCGGCGCCCG GTGAAGGTGT ACCCCAACGG CGCCGAGGAC 
GAGTCGGCCC AGGCCTTTCC CCTCGAATTC AAGAGGGAGC TGACCGGGGA GAGGCTCGAG 
CAGGCGCGCG GCCCCGAGGC CCAGGCTGAG AGTGCGGCCG CCCGGGCTGA GCTGGAGTAT 
GGCCTGGTGG CGGAGGCGGA GGCTGAGGCG GCCGAGAAGA AGGACTCGGG GCCCTATAAG 
ATGGAACACT TCCGCTGGGG CAGCCCGCCC AAGGACAAGC GCTACGGCGG GTTCATGACC 
TCCGAGAAGA GCCAAACGCC CCTTGTCACG CTGTTCAAAA ACGCCATCAT CAAGAACGCC 
CACAAGAAGG GCCAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

POMC ( XM_010810166.2 ) cDNA ORF clone, Bos taurus(cattle) -> XP_010808468.1 Bos taurus proopiomelanocortin (POMC), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OBa45136
Clone ID Related Accession (Same CDS sequence)	XM_010810166.2 , XM_010810166.1
Accession Version	XM_010810166.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 852bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-05-06
Organism	Bos taurus(cattle)
Product	pro-opiomelanocortin isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_037338.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On May 7, 2018 this sequence version replaced XM_010810166.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Bos taurus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAAGCTC AGACAAGACG CAGGCTCAGG CAAGAGCCTC AGCCTGCCTG GAAGATGCCG 
AGACTGTGCA GCAGTCGTTC GGGCGCCCTG CTGCTGGCCT TGCTGCTTCA GGCCTCCATG 
GAAGTGCGTG GTTGGTGCCT GGAGAGCAGC CAGTGTCAGG ACCTCACCAC GGAAAGTAAC 
CTGCTGGCGT GCATCCGGGC CTGCAAGCCC GACCTCTCCG CCGAGACGCC GGTGTTCCCC 
GGCAACGGCG ATGAGCAGCC GCTGACTGAG AACCCCCGGA AGTACGTCAT GGGCCATTTC 
CGCTGGGACC GCTTCGGCCG TCGGAATGGT AGCAGCAGCA GCGGAGTTGG GGGCGCGGCC 
CAGAAGCGCG AGGAGGAAGT GGCGGTGGGC GAAGGCCCCG GGCCCCGCGG CGATGACGCC 
GAGACGGGTC CGCGCGAGGA CAAGCGTTCT TACTCCATGG AACACTTCCG CTGGGGCAAG 
CCGGTGGGCA AGAAGCGGCG CCCGGTGAAG GTGTACCCCA ACGGCGCCGA GGACGAGTCG 
GCCCAGGCCT TTCCCCTCGA ATTCAAGAGG GAGCTGACCG GGGAGAGGCT CGAGCAGGCG 
CGCGGCCCCG AGGCCCAGGC TGAGAGTGCG GCCGCCCGGG CTGAGCTGGA GTATGGCCTG 
GTGGCGGAGG CGGAGGCTGA GGCGGCCGAG AAGAAGGACT CGGGGCCCTA TAAGATGGAA 
CACTTCCGCT GGGGCAGCCC GCCCAAGGAC AAGCGCTACG GCGGGTTCAT GACCTCCGAG 
AAGAGCCAAA CGCCCCTTGT CACGCTGTTC AAAAACGCCA TCATCAAGAA CGCCCACAAG 
AAGGGCCAGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_010808468.1
CDS	306..1157
Translation	MEAQTRRRLRQEPQPAWKMPRLCSSRSGALLLALLLQASMEVRGWCLESSQCQDLTTESNLLACIRACKPDLSAETPVFPGNGDEQPLTENPRKYVMGHFRWDRFGRRNGSSSSGVGGAAQKREEEVAVGEGPGPRGDDAETGPREDKRSYSMEHFRWGKPVGKKRRPVKVYPNGAEDESAQAFPLEFKRELTGERLEQARGPEAQAESAAARAELEYGLVAEAEAEAAEKKDSGPYKMEHFRWGSPPKDKRYGGFMTSEKSQTPLVTLFKNAIIKNAHKKGQ

Target ORF information:

RefSeq Version	XM_010810166.2
Organism	Bos taurus(cattle)
Definition	Bos taurus proopiomelanocortin (POMC), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_010810166.2

ORF Insert Sequence:

ATGGAAGCTC AGACAAGACG CAGGCTCAGG CAAGAGCCTC AGCCTGCCTG GAAGATGCCG 
AGACTGTGCA GCAGTCGTTC GGGCGCCCTG CTGCTGGCCT TGCTGCTTCA GGCCTCCATG 
GAAGTGCGTG GTTGGTGCCT GGAGAGCAGC CAGTGTCAGG ACCTCACCAC GGAAAGTAAC 
CTGCTGGCGT GCATCCGGGC CTGCAAGCCC GACCTCTCCG CCGAGACGCC GGTGTTCCCC 
GGCAACGGCG ATGAGCAGCC GCTGACTGAG AACCCCCGGA AGTACGTCAT GGGCCATTTC 
CGCTGGGACC GCTTCGGCCG TCGGAATGGT AGCAGCAGCA GCGGAGTTGG GGGCGCGGCC 
CAGAAGCGCG AGGAGGAAGT GGCGGTGGGC GAAGGCCCCG GGCCCCGCGG CGATGACGCC 
GAGACGGGTC CGCGCGAGGA CAAGCGTTCT TACTCCATGG AACACTTCCG CTGGGGCAAG 
CCGGTGGGCA AGAAGCGGCG CCCGGTGAAG GTGTACCCCA ACGGCGCCGA GGACGAGTCG 
GCCCAGGCCT TTCCCCTCGA ATTCAAGAGG GAGCTGACCG GGGAGAGGCT CGAGCAGGCG 
CGCGGCCCCG AGGCCCAGGC TGAGAGTGCG GCCGCCCGGG CTGAGCTGGA GTATGGCCTG 
GTGGCGGAGG CGGAGGCTGA GGCGGCCGAG AAGAAGGACT CGGGGCCCTA TAAGATGGAA 
CACTTCCGCT GGGGCAGCCC GCCCAAGGAC AAGCGCTACG GCGGGTTCAT GACCTCCGAG 
AAGAGCCAAA CGCCCCTTGT CACGCTGTTC AAAAACGCCA TCATCAAGAA CGCCCACAAG 
AAGGGCCAGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

POMC ( XM_010810166.1 ) cDNA ORF clone, Bos taurus(cattle) -> XP_010808468.1 Bos taurus proopiomelanocortin (POMC), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OBa45136
Clone ID Related Accession (Same CDS sequence)	XM_010810166.2 , XM_010810166.1
Accession Version	XM_010810166.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 852bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-01-25
Organism	Bos taurus(cattle)
Product	pro-opiomelanocortin isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003104296.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Bos taurus Annotation Release 105 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.5 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAAGCTC AGACAAGACG CAGGCTCAGG CAAGAGCCTC AGCCTGCCTG GAAGATGCCG 
AGACTGTGCA GCAGTCGTTC GGGCGCCCTG CTGCTGGCCT TGCTGCTTCA GGCCTCCATG 
GAAGTGCGTG GTTGGTGCCT GGAGAGCAGC CAGTGTCAGG ACCTCACCAC GGAAAGTAAC 
CTGCTGGCGT GCATCCGGGC CTGCAAGCCC GACCTCTCCG CCGAGACGCC GGTGTTCCCC 
GGCAACGGCG ATGAGCAGCC GCTGACTGAG AACCCCCGGA AGTACGTCAT GGGCCATTTC 
CGCTGGGACC GCTTCGGCCG TCGGAATGGT AGCAGCAGCA GCGGAGTTGG GGGCGCGGCC 
CAGAAGCGCG AGGAGGAAGT GGCGGTGGGC GAAGGCCCCG GGCCCCGCGG CGATGACGCC 
GAGACGGGTC CGCGCGAGGA CAAGCGTTCT TACTCCATGG AACACTTCCG CTGGGGCAAG 
CCGGTGGGCA AGAAGCGGCG CCCGGTGAAG GTGTACCCCA ACGGCGCCGA GGACGAGTCG 
GCCCAGGCCT TTCCCCTCGA ATTCAAGAGG GAGCTGACCG GGGAGAGGCT CGAGCAGGCG 
CGCGGCCCCG AGGCCCAGGC TGAGAGTGCG GCCGCCCGGG CTGAGCTGGA GTATGGCCTG 
GTGGCGGAGG CGGAGGCTGA GGCGGCCGAG AAGAAGGACT CGGGGCCCTA TAAGATGGAA 
CACTTCCGCT GGGGCAGCCC GCCCAAGGAC AAGCGCTACG GCGGGTTCAT GACCTCCGAG 
AAGAGCCAAA CGCCCCTTGT CACGCTGTTC AAAAACGCCA TCATCAAGAA CGCCCACAAG 
AAGGGCCAGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_010808468.1
CDS	308..1159
Translation	MEAQTRRRLRQEPQPAWKMPRLCSSRSGALLLALLLQASMEVRGWCLESSQCQDLTTESNLLACIRACKPDLSAETPVFPGNGDEQPLTENPRKYVMGHFRWDRFGRRNGSSSSGVGGAAQKREEEVAVGEGPGPRGDDAETGPREDKRSYSMEHFRWGKPVGKKRRPVKVYPNGAEDESAQAFPLEFKRELTGERLEQARGPEAQAESAAARAELEYGLVAEAEAEAAEKKDSGPYKMEHFRWGSPPKDKRYGGFMTSEKSQTPLVTLFKNAIIKNAHKKGQ

Target ORF information:

RefSeq Version	XM_010810166.1
Organism	Bos taurus(cattle)
Definition	Bos taurus proopiomelanocortin (POMC), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_010810166.1

ORF Insert Sequence:

ATGGAAGCTC AGACAAGACG CAGGCTCAGG CAAGAGCCTC AGCCTGCCTG GAAGATGCCG 
AGACTGTGCA GCAGTCGTTC GGGCGCCCTG CTGCTGGCCT TGCTGCTTCA GGCCTCCATG 
GAAGTGCGTG GTTGGTGCCT GGAGAGCAGC CAGTGTCAGG ACCTCACCAC GGAAAGTAAC 
CTGCTGGCGT GCATCCGGGC CTGCAAGCCC GACCTCTCCG CCGAGACGCC GGTGTTCCCC 
GGCAACGGCG ATGAGCAGCC GCTGACTGAG AACCCCCGGA AGTACGTCAT GGGCCATTTC 
CGCTGGGACC GCTTCGGCCG TCGGAATGGT AGCAGCAGCA GCGGAGTTGG GGGCGCGGCC 
CAGAAGCGCG AGGAGGAAGT GGCGGTGGGC GAAGGCCCCG GGCCCCGCGG CGATGACGCC 
GAGACGGGTC CGCGCGAGGA CAAGCGTTCT TACTCCATGG AACACTTCCG CTGGGGCAAG 
CCGGTGGGCA AGAAGCGGCG CCCGGTGAAG GTGTACCCCA ACGGCGCCGA GGACGAGTCG 
GCCCAGGCCT TTCCCCTCGA ATTCAAGAGG GAGCTGACCG GGGAGAGGCT CGAGCAGGCG 
CGCGGCCCCG AGGCCCAGGC TGAGAGTGCG GCCGCCCGGG CTGAGCTGGA GTATGGCCTG 
GTGGCGGAGG CGGAGGCTGA GGCGGCCGAG AAGAAGGACT CGGGGCCCTA TAAGATGGAA 
CACTTCCGCT GGGGCAGCCC GCCCAAGGAC AAGCGCTACG GCGGGTTCAT GACCTCCGAG 
AAGAGCCAAA CGCCCCTTGT CACGCTGTTC AAAAACGCCA TCATCAAGAA CGCCCACAAG 
AAGGGCCAGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Pituitary genomic expression profiles of steers are altered by grazing of high vs. low endophyte-infected tall fescue forages.
PloS one12(9)e0184612(2017)
Li Q,Hegge R,Bridges PJ,Matthews JC

Association between polymorphisms of the CRH and POMC genes with economic traits in Korean cattle (Hanwoo).
Genetics and molecular research : GMR14(3)10415-21(2015 Sep)
Seong J,Kong HS

Endocannabinoid system and proopiomelanocortin gene expression in peripartal bovine liver in response to prepartal plane of nutrition.
Journal of animal physiology and animal nutrition96(5)907-19(2012 Oct)
Khan MJ,Graugnard DE,Loor JJ

Characterization of two pro-opiomelanocortin gene variants and their effects on carcass traits in beef cattle.
BMC genetics122(2011 Jan)
Deobald HM,Buchanan FC

[The polymorphism of bovine POMC gene and its association with the growth traits of Nanyang cattle].
Yi chuan = Hereditas31(12)1221-5(2009 Dec)
Zhang CL,Wang YH,Chen H,Lei CZ,Fang XT,Wang JQ,Ma GB,Niu H,Xiao J