| Gene Symbol | PARP1 |
| Entrez Gene ID | 817690 |
| Full Name | poly(ADP-ribose) polymerase 2 |
| Synonyms | ATPARP2,F16D14.16,F16D14_16,POLY(ADP-RIBOSE) POLYMERASE 1,poly(ADP-ribose) polymerase 2 |
| Gene Type | protein-coding |
| Organism | Arabidopsis thaliana(thale cress) |
ORF » Species Summary » Arabidopsis thaliana » PARP1 cDNA ORF clone
| Gene Symbol | PARP1 |
| Entrez Gene ID | 817690 |
| Full Name | poly(ADP-ribose) polymerase 2 |
| Synonyms | ATPARP2,F16D14.16,F16D14_16,POLY(ADP-RIBOSE) POLYMERASE 1,poly(ADP-ribose) polymerase 2 |
| Gene Type | protein-coding |
| Organism | Arabidopsis thaliana(thale cress) |
| mRNA | Protein | Name |
|---|---|---|
| NM_179834.2 | NP_850165.1 | poly(ADP-ribose) polymerase 2 |
| Drosophila melanogaster (fruit fly) | Parp | NP_001104452.1 |
| Arabidopsis thaliana (thale cress) | PARP1 | NP_850165.1 |
| Oryza sativa (rice) | Os07g0413700 | NP_001059453.1 |
| Homo sapiens (human) | PARP1 | NP_001609.2 |
| Pan troglodytes (chimpanzee) | PARP1 | XP_003949754.1 |
| Canis lupus familiaris (dog) | PARP1 | XP_547506.3 |
| Bos taurus (cattle) | PARP1 | NP_777176.1 |
| PARP1 | XP_001090984.1 | |
| Gallus gallus (chicken) | PARP1 | NP_990594.1 |
| Xenopus tropicalis (tropical clawed frog) | parp1 | XP_002941174.2 |
| Danio rerio (zebrafish) | parp1 | NP_001038407.1 |
| Caenorhabditis elegans (roundworm) | pme-1 | NP_491072.1 |
| Mus musculus (house mouse) | Parp1 | NP_031441.2 |
| Rattus norvegicus (Norway rat) | Parp1 | NP_037195.1 |
| Anopheles gambiae (African malaria mosquito) | AgaP_AGAP003230 | XP_312938.4 |
Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.
Lin X, Kaul S, Rounsley S, Shea TP, Benito MI, Town CD, Fujii CY, Mason T, Bowman CL, Barnstead M, Feldblyum TV, Buell CR, Ketchum KA, Lee J, Ronning CM, Koo HL, Moffat KS, Cronin LA, Shen M, Pai G, Van Aken S, Umayam L, Tallon LJ, Gill JE, Adams MD, Carrera AJ, Creasy TH, Goodman HM, Somerville CR, Copenhaver GP, Preuss D, Nierman WC, White O, Eisen JA, Salzberg SL, Fraser CM, Venter JC
Nature402(6763)761-8(1999 Dec)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
We found that larger deletions of >20 bp predominated after DSB repair in ku80 and ku80 parp1 parp2 mutants, corroborating with a role of KU in preventing DSB end resection. Deletion lengths did not significantly differ between ku80 and ku80 parp1 parp2 mutants, suggesting that a KU- and PARP-independent b-NHEJ mechanism becomes active in these mutants.
Title: CRISPR/Cas9-Induced Double-Strand Break Repair in Arabidopsis Nonhomologous End-Joining Mutants.
whilst all isoforms of PARP were localized to the nucleus they are also present in non-nuclear locations with parp1 and parp3 also localised in the cytosol, and parp2 also present in the mitochondria
Title: Analysis of knockout mutants reveals non-redundant functions of poly(ADP-ribose)polymerase isoforms in Arabidopsis.
Studies indicate that a massive and rapid accumulation of a massive and rapid accumulation poly(ADP-ribose) polymerases AtPARP1 and AtPARP2 transcripts was observed upon treatment with ionizing radiation and reactive oxigen species (ROS).
Title: Synthesis and degradation of poly(ADP-ribose) in plants.
PARP isoforms play a minor role in telomere length maintenance in Arabidopsis.
Title: Analysis of poly(ADP-Ribose) polymerases in Arabidopsis telomere biology.
Evidence suggests a link between the glutathione pool and PARP expression and activity that is perhaps related to the distribution of intracellular glutathione between the cytoplasm and the nucleus. [PARP1]
Title: Pyridine nucleotide cycling and control of intracellular redox state in relation to poly (ADP-ribose) polymerase activity and nuclear localization of glutathione during exponential growth of Arabidopsis cells in culture.
The following PARP1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the PARP1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | OAb08444 | |
| Clone ID Related Accession (Same CDS sequence) | NM_179834.2 | |
| Accession Version | NM_179834.2 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 2952bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-02-13 | |
| Organism | Arabidopsis thaliana(thale cress) | |
| Product | poly(ADP-ribose) polymerase 2 | |
| Comment | Comment: REVIEWED REFSEQ: This record has been curated by TAIR and Araport. This record is derived from an annotated genomic sequence (NC_003071). On Sep 12, 2016 this sequence version replaced NM_179834.1. | |
1 | ATGGCAAGCC CACATAAGCC GTGGAGGGCG GAGTATGCAA AGTCGTCGAG GTCTTCATGT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_850165.1 |
| CDS | 173..3124 |
| Translation |
Target ORF information:
Target ORF information:
|
NM_179834.2 |
1 | ATGGCAAGCC CACATAAGCC GTGGAGGGCG GAGTATGCAA AGTCGTCGAG GTCTTCATGT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana. |