BCMA(TNFRSF17) hFc Chimera [iFluor 647], Human
BCMA(TNFRSF17) HFc Chimera [iFluor 647], Human

Flow cytometric analysis of anti-BCMA-based CAR-T cells using BCMA(TNFRSF17) hFc Chimera [iFluor 647], Human (Z06803).
The results show that Z06803 can achieve good cell clustering for CAR-transduced T cells.

BCMA(TNFRSF17) hFc Chimera [iFluor 647], Human

B-cell maturation antigen (BCMA or BCM), also known as tumor necrosis factor receptor superfamily member 17 (TNFRSF17), is a protein that in humans is encoded by the TNFRSF17 gene.TNFRSF17 is a cell surface receptor of the TNF receptor superfamily which recognizes B-cell activating factor (BAFF).
Z06803
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Product Introduction
Species Human
Protein Construction
BCMA/TNFRSF17 (Met1-Ala54)
Accession # Q02223-1		 hFc
N-term C-term
Conjugate iFluor 647
Biological Activity Immobilized Human BAFF/TNFSF13B/CD257, His at 1 μg/ml (100μl/well) on the plate can bind BCMA(TNFRSF17) hFc Chimera [iFluor 647], Human (Cat.No.: Z06803).
Theoretical Molecular Weight 31.4 kDa
Formulation Supplied in PBS (pH 7.2), containing 10 mg/ml BSA, 0.03% ProClin300 and 50% glycerol.
Concentration 0.5 mg/mL
Storage & Stability Store at -20°C. This product is stable for 1 year upon receipt, when handled and stored as instructed.

Applications
Working concentrations for specific applications should be determined by the investigators. The appropriate concentrations may be affected by secondary antibody affinity, antigen concentration, the sensitivity of the method of detection, temperature, the length of the incubations, and other factors. The suitability of this antibody for applications other than those listed below has not been determined. The following concentration ranges are recommended starting points for this product.
Application Recommended Usage
Flow Cytometry 1 µg/ml-10 µg/ml

Examples
  • BCMA(TNFRSF17) HFc Chimera [iFluor 647], Human
    • BCMA(TNFRSF17) HFc Chimera [iFluor 647], Human

    Flow cytometric analysis of anti-BCMA-based CAR-T cells using BCMA(TNFRSF17) hFc Chimera [iFluor 647], Human (Z06803).
    The results show that Z06803 can achieve good cell clustering for CAR-transduced T cells.


Background
Target Background BCMA (B-cell maturation antigen), also called TNFRSF17, is encoded by the TNFRSF17 gene. It acts as a cell surface receptor of the TNF receptor superfamily. BCMA recognizes B-cell activating factor (BAFF). It interacts with the B-cell activating factor TNFSF13B.
Synonyms CD269; TNFRSF17; BCMA; BCM; TNFRSF13A

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.