DBF4 Antibody, mAb, Rabbit
DBF4 Antibody, MAb, Rabbit

Western blot analysis of DBF4 expression in Jurkat cell lysate.

DBF4 Antibody, mAb, Rabbit

Regulatory subunit for CDC7 which activates its kinase activity thereby playing a central role in DNA replication and cell proliferation. Required for progression of S phase. The complex CDC7-DBF4A selectively phosphorylates MCM2 subunit at 'Ser-40' and 'Ser-53' and then is involved in regulating the initiation of DNA replication during cell cycle.
A05209
¥37,309.00

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Overview
Specificity This product is specific to DBF4
Host Species Rabbit
Immunogen A synthesized peptide derived from human DBF4
Species Reactivity Human
Conjugate Unconjugated

Applications
Working concentrations for specific applications should be determined by the investigators. The appropriate concentrations may be affected by secondary antibody affinity, antigen concentration, the sensitivity of the method of detection, temperature, the length of the incubations, and other factors. The suitability of this antibody for applications other than those listed below has not been determined. The following concentration ranges are recommended starting points for this product.
Application Recommended Usage
Western Blot 1:1000-1:2000

Properties
Form Liquid
Storage Buffer Supplied in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.
Storage Instructions Store at -20°C. This product is stable for 1 year upon receipt, when handled and stored as instructed.
Purification Affinity-chromatography
Isotype Rabbit IgG
Clonality Monoclonal

Examples
  • DBF4 Antibody, MAb, Rabbit
    • DBF4 Antibody, MAb, Rabbit

    Western blot analysis of DBF4 expression in Jurkat cell lysate.


Background
Target Background Regulatory subunit for CDC7 which activates its kinase activity thereby playing a central role in DNA replication and cell proliferation. Required for progression of S phase. The complex CDC7-DBF4A selectively phosphorylates MCM2 subunit at 'Ser-40' and 'Ser-53' and then is involved in regulating the initiation of DNA replication during cell cycle.
Synonyms ASK; CHIF; DBF4; DBF4 zinc finger A; DBF4A; ZDBF1;

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.