MAD3 Antibody, mAb, Rabbit
MAD3 Antibody, MAb, Rabbit

Western blot analysis of MAD3 expression in HeLa cell lysate.

MAD3 Antibody, mAb, Rabbit

Transcriptional repressor. Binds with MAX to form a sequence-specific DNA-binding protein complex which recognizes the core sequence 5'-CAC[GA]TG-3'. Antagonizes MYC transcriptional activity by competing for MAX and suppresses MYC dependent cell transformation.
A05137
¥37,309.00

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Overview
Specificity This product is specific to MAD3
Host Species Rabbit
Immunogen A synthesized peptide derived from human MAD3
Species Reactivity Human; Mouse; Rat
Conjugate Unconjugated

Applications
Working concentrations for specific applications should be determined by the investigators. The appropriate concentrations may be affected by secondary antibody affinity, antigen concentration, the sensitivity of the method of detection, temperature, the length of the incubations, and other factors. The suitability of this antibody for applications other than those listed below has not been determined. The following concentration ranges are recommended starting points for this product.
Application Recommended Usage
Western Blot 1:1000-1:2000
Immunohistochemistry (IHC) 1:100-1:200
Flow Cytometry 1:20-1:100

Properties
Form Liquid
Storage Buffer Supplied in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.
Storage Instructions Store at -20°C. This product is stable for 1 year upon receipt, when handled and stored as instructed.
Purification Affinity-chromatography
Isotype Rabbit IgG
Clonality Monoclonal

Examples
  • MAD3 Antibody, MAb, Rabbit
    • MAD3 Antibody, MAb, Rabbit

    Western blot analysis of MAD3 expression in HeLa cell lysate.


Background
Target Background Transcriptional repressor. Binds with MAX to form a sequence-specific DNA-binding protein complex which recognizes the core sequence 5'-CAC[GA]TG-3'. Antagonizes MYC transcriptional activity by competing for MAX and suppresses MYC dependent cell transformation.
Synonyms bHLHc13; mxd3; Myx;

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.