TC10 Antibody, mAb, Rabbit
TC10 Antibody, MAb, Rabbit

Western blot analysis of TC10 expression in 293T cell lysate.

TC10 Antibody, mAb, Rabbit

Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. May play a role in CFTR trafficking to the plasma membrane. Causes the formation of thin, actin-rich surface projections called filopodia.
A05109
¥37,309.00

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Overview
Specificity This product is specific to TC10
Host Species Rabbit
Immunogen A synthesized peptide derived from human TC10
Species Reactivity Human; Rat
Conjugate Unconjugated

Applications
Working concentrations for specific applications should be determined by the investigators. The appropriate concentrations may be affected by secondary antibody affinity, antigen concentration, the sensitivity of the method of detection, temperature, the length of the incubations, and other factors. The suitability of this antibody for applications other than those listed below has not been determined. The following concentration ranges are recommended starting points for this product.
Application Recommended Usage
Western Blot 1:1000-1:2000
Immunocytochemistry/Immunofluorescence (ICC/IF) 1:50-1:200

Properties
Form Liquid
Storage Buffer Supplied in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.
Storage Instructions Store at -20°C. This product is stable for 1 year upon receipt, when handled and stored as instructed.
Purification Affinity-chromatography
Isotype Rabbit IgG
Clonality Monoclonal

Examples
  • TC10 Antibody, MAb, Rabbit
    • TC10 Antibody, MAb, Rabbit

    Western blot analysis of TC10 expression in 293T cell lysate.


Background
Target Background Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. May play a role in CFTR trafficking to the plasma membrane. Causes the formation of thin, actin-rich surface projections called filopodia.
Synonyms ARHQ; RASL7A; Rho related GTP binding protein RhoQ; Rhoq; TC10A;

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.