GAB1 Antibody, mAb, Rabbit
GAB1 Antibody, MAb, Rabbit

Western blot analysis of GAB1 expression in HEK293 cell lysate.

GAB1 Antibody, mAb, Rabbit

Adapter protein that plays a role in intracellular signaling cascades triggered by activated receptor-type kinases. Plays a role in FGFR1 signaling. Probably involved in signaling by the epidermal growth factor receptor (EGFR) and the insulin receptor (INSR). Involved in the MET/HGF-signaling pathway.
A04980
¥37,309.00

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Overview
Specificity This product is specific to GAB1
Host Species Rabbit
Immunogen A synthesized peptide derived from human GAB1
Species Reactivity Human; Mouse; Rat
Conjugate Unconjugated

Applications
Working concentrations for specific applications should be determined by the investigators. The appropriate concentrations may be affected by secondary antibody affinity, antigen concentration, the sensitivity of the method of detection, temperature, the length of the incubations, and other factors. The suitability of this antibody for applications other than those listed below has not been determined. The following concentration ranges are recommended starting points for this product.
Application Recommended Usage
Western Blot 1:1000-1:2000
Immunocytochemistry/Immunofluorescence (ICC/IF) 1:50-1:200
Flow Cytometry 1:20-1:100

Properties
Form Liquid
Storage Buffer Supplied in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.
Storage Instructions Store at -20°C. This product is stable for 1 year upon receipt, when handled and stored as instructed.
Purification Affinity-chromatography
Isotype Rabbit IgG
Clonality Monoclonal

Examples
  • GAB1 Antibody, MAb, Rabbit
    • GAB1 Antibody, MAb, Rabbit

    Western blot analysis of GAB1 expression in HEK293 cell lysate.


Background
Target Background Adapter protein that plays a role in intracellular signaling cascades triggered by activated receptor-type kinases. Plays a role in FGFR1 signaling. Probably involved in signaling by the epidermal growth factor receptor (EGFR) and the insulin receptor (INSR). Involved in the MET/HGF-signaling pathway.
Synonyms GAB1; GRB 2 associated binder 1;

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.