LIMK 1 Antibody, mAb, Rabbit
LIMK 1 Antibody, MAb, Rabbit

Western blot analysis of LIM Kinase 1 expression in U-87MG cell lysate.

LIMK 1 Antibody, mAb, Rabbit

Serine/threonine-protein kinase that plays an essential role in the regulation of actin filament dynamics. Acts downstream of several Rho family GTPase signal transduction pathways.Activated by upstream kinases including ROCK1, PAK1 and PAK4, which phosphorylate LIMK1 on a threonine residue located in its activation loop.
A04940
¥37,309.00

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Overview
Specificity This product is specific to LIMK 1
Host Species Rabbit
Immunogen A synthesized peptide derived from human LIMK 1
Species Reactivity Human; Mouse; Rat
Conjugate Unconjugated

Applications
Working concentrations for specific applications should be determined by the investigators. The appropriate concentrations may be affected by secondary antibody affinity, antigen concentration, the sensitivity of the method of detection, temperature, the length of the incubations, and other factors. The suitability of this antibody for applications other than those listed below has not been determined. The following concentration ranges are recommended starting points for this product.
Application Recommended Usage
Western Blot 1:1000-1:2000

Properties
Form Liquid
Storage Buffer Supplied in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.
Storage Instructions Store at -20°C. This product is stable for 1 year upon receipt, when handled and stored as instructed.
Purification Affinity-chromatography
Isotype Rabbit IgG
Clonality Monoclonal

Examples
  • LIMK 1 Antibody, MAb, Rabbit
    • LIMK 1 Antibody, MAb, Rabbit

    Western blot analysis of LIM Kinase 1 expression in U-87MG cell lysate.


Background
Target Background Serine/threonine-protein kinase that plays an essential role in the regulation of actin filament dynamics. Acts downstream of several Rho family GTPase signal transduction pathways.Activated by upstream kinases including ROCK1, PAK1 and PAK4, which phosphorylate LIMK1 on a threonine residue located in its activation loop.
Synonyms LIM kinase; LIMK 1; LIMK;

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.