ACVR2A Antibody, mAb, Rabbit
ACVR2A Antibody, MAb, Rabbit

Western blot analysis of Activin Receptor Type IIA expression in HeLa cell lysate.

ACVR2A Antibody, mAb, Rabbit

On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for activin A, activin B and inhibin A.
A04847
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Overview
Specificity This product is specific to ACVR2A
Host Species Rabbit
Immunogen A synthesized peptide derived from human ACVR2A
Species Reactivity Human; Mouse; Rat
Conjugate Unconjugated

Applications
Working concentrations for specific applications should be determined by the investigators. The appropriate concentrations may be affected by secondary antibody affinity, antigen concentration, the sensitivity of the method of detection, temperature, the length of the incubations, and other factors. The suitability of this antibody for applications other than those listed below has not been determined. The following concentration ranges are recommended starting points for this product.
Application Recommended Usage
Western Blot 1:1000-1:2000

Properties
Form Liquid
Storage Buffer Supplied in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.
Storage Instructions Store at -20°C. This product is stable for 1 year upon receipt, when handled and stored as instructed.
Purification Affinity-chromatography
Isotype Rabbit IgG
Clonality Monoclonal

Examples
  • ACVR2A Antibody, MAb, Rabbit
    • ACVR2A Antibody, MAb, Rabbit

    Western blot analysis of Activin Receptor Type IIA expression in HeLa cell lysate.


Background
Target Background On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for activin A, activin B and inhibin A.
Synonyms ACTR2; ACTRII; ACTRIIA; Acvr2; ACVR2A;

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.