UBR5 Antibody, mAb, Rabbit
UBR5 Antibody, MAb, Rabbit

Western blot analysis of EDD expression in SH-SY5Y cell lysate.

UBR5 Antibody, mAb, Rabbit

E3 ubiquitin-protein ligase which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.
A04679
¥37,309.00

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Overview
Specificity This product is specific to UBR5
Host Species Rabbit
Immunogen A synthesized peptide derived from human UBR5
Species Reactivity Human; Mouse
Conjugate Unconjugated

Applications
Working concentrations for specific applications should be determined by the investigators. The appropriate concentrations may be affected by secondary antibody affinity, antigen concentration, the sensitivity of the method of detection, temperature, the length of the incubations, and other factors. The suitability of this antibody for applications other than those listed below has not been determined. The following concentration ranges are recommended starting points for this product.
Application Recommended Usage
Western Blot 1:1000-1:2000

Properties
Form Liquid
Storage Buffer Supplied in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.
Storage Instructions Store at -20°C. This product is stable for 1 year upon receipt, when handled and stored as instructed.
Purification Affinity-chromatography
Isotype Rabbit IgG
Clonality Monoclonal

Examples
  • UBR5 Antibody, MAb, Rabbit
    • UBR5 Antibody, MAb, Rabbit

    Western blot analysis of EDD expression in SH-SY5Y cell lysate.


Background
Target Background E3 ubiquitin-protein ligase which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.
Synonyms DD5; EDD; EDD1; hHYD; HYD; Rat100; Ubiquitin protein ligase; UBR5;

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.