UBA2 Antibody, mAb, Rabbit
UBA2 Antibody, MAb, Rabbit

Western blot analysis of SAE2 / UBA2 expression in A549 cell lysate.

UBA2 Antibody, mAb, Rabbit

The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2.
A04021
¥37,309.00

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Overview
Specificity This product is specific to UBA2
Host Species Rabbit
Immunogen A synthesized peptide derived from human UBA2
Species Reactivity Human; Mouse; Rat
Conjugate Unconjugated

Applications
Working concentrations for specific applications should be determined by the investigators. The appropriate concentrations may be affected by secondary antibody affinity, antigen concentration, the sensitivity of the method of detection, temperature, the length of the incubations, and other factors. The suitability of this antibody for applications other than those listed below has not been determined. The following concentration ranges are recommended starting points for this product.
Application Recommended Usage
Western Blot 1:1000-1:2000
Immunohistochemistry (IHC) 1:100-1:200
Immunocytochemistry/Immunofluorescence (ICC/IF) 1:50-1:200
Immunohistochemistry Frozen (IHF) 1:50-1:200
Immunoprecipitation (IP) 1:20-1:50

Properties
Form Liquid
Storage Buffer Supplied in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.
Storage Instructions Store at -20°C. This product is stable for 1 year upon receipt, when handled and stored as instructed.
Purification Affinity-chromatography
Isotype Rabbit IgG
Clonality Monoclonal

Examples
  • UBA2 Antibody, MAb, Rabbit
    • UBA2 Antibody, MAb, Rabbit

    Western blot analysis of SAE2 / UBA2 expression in A549 cell lysate.


Background
Target Background The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2.
Synonyms ARX; SAE2; UBA2; UBLE1B;

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.