NR4A1 Antibody, mAb, Rabbit
NR4A1 Antibody, MAb, Rabbit

Western blot analysis of NUR77 expression in HepG2 cell lysate.

NR4A1 Antibody, mAb, Rabbit

In the cytosol, upon its detection of both bacterial lipopolysaccharide (LPS) and NBRE-containing mitochondrial DNA released by GSDMD pores during pyroptosis, it promotes non-canonical NLRP3 inflammasome activation by stimulating association of NLRP3 and NEK7.
A03700
¥37,309.00

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Overview
Specificity This product is specific to NR4A1
Host Species Rabbit
Immunogen A synthesized peptide derived from human NR4A1
Species Reactivity Human; Mouse; Rat
Conjugate Unconjugated

Applications
Working concentrations for specific applications should be determined by the investigators. The appropriate concentrations may be affected by secondary antibody affinity, antigen concentration, the sensitivity of the method of detection, temperature, the length of the incubations, and other factors. The suitability of this antibody for applications other than those listed below has not been determined. The following concentration ranges are recommended starting points for this product.
Application Recommended Usage
Western Blot 1:1000-1:2000

Properties
Form Liquid
Storage Buffer Supplied in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.
Storage Instructions Store at -20°C. This product is stable for 1 year upon receipt, when handled and stored as instructed.
Purification Affinity-chromatography
Isotype Rabbit IgG
Clonality Monoclonal

Examples
  • NR4A1 Antibody, MAb, Rabbit
    • NR4A1 Antibody, MAb, Rabbit

    Western blot analysis of NUR77 expression in HepG2 cell lysate.


Background
Target Background In the cytosol, upon its detection of both bacterial lipopolysaccharide (LPS) and NBRE-containing mitochondrial DNA released by GSDMD pores during pyroptosis, it promotes non-canonical NLRP3 inflammasome activation by stimulating association of NLRP3 and NEK7.
Synonyms Nur77; Orphan nuclear receptor HMR; Orphan nuclear receptor TR3; ST-59; Testicular receptor 3; NR4A1; GFRP1; HMR; NAK1;

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.