Western blot analysis of NLRP3 expression in SH-SY5Y cell lysate.
| A03034 | |
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| ¥37,309.00 | |
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| Specificity | This product is specific to NLRP3 |
| Host Species | Rabbit |
| Immunogen | A synthesized peptide derived from human NLRP3 |
| Species Reactivity | Human; Mouse; Rat |
| Conjugate | Unconjugated |
| Working concentrations for specific applications should be determined by the investigators. The appropriate concentrations may be affected by secondary antibody affinity, antigen concentration, the sensitivity of the method of detection, temperature, the length of the incubations, and other factors. The suitability of this antibody for applications other than those listed below has not been determined. The following concentration ranges are recommended starting points for this product. | |||||||||||
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| Form | Liquid |
| Storage Buffer | Supplied in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol. |
| Storage Instructions | Store at -20°C. This product is stable for 1 year upon receipt, when handled and stored as instructed. |
| Purification | Affinity-chromatography |
| Isotype | Rabbit IgG |
| Clonality | Monoclonal |
Western blot analysis of NLRP3 expression in SH-SY5Y cell lysate.
| Target Background | Sensor component of the NLRP3 inflammasome, which mediates inflammasome activation in response to defects in membrane integrity, leading to secretion of inflammatory cytokines IL1B and IL18 and pyroptosis. |
| Synonyms | FCU; MWS; FCAS; Cias1; Mmig1; NLRP3; Pypaf1; AII/AVP; AGTAVPRL; Cryopyrin; |
For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.
