Caspase 8 Antibody, mAb, Rabbit
Caspase 8 Antibody, MAb, Rabbit

All lanes use Caspase 8 Antibody, mAb, Rabbit at 1:1K dilution for 1 hour at room temperature.

Caspase 8 Antibody, mAb, Rabbit

Thiol protease that plays a key role in programmed cell death by acting as a molecular switch for apoptosis, necroptosis and pyroptosis, and is required to prevent tissue damage during embryonic development and adulthood.Initiator protease that induces extrinsic apoptosis by mediating cleavage and activation of effector caspases responsible for FAS/CD95-mediated and TNFRSF1A-induced cell death.
A02448
¥37,309.00

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Overview
Specificity This product is specific to Caspase 8
Host Species Rabbit
Immunogen A synthesized peptide derived from human Caspase 8
Species Reactivity Human
Conjugate Unconjugated

Applications
Working concentrations for specific applications should be determined by the investigators. The appropriate concentrations may be affected by secondary antibody affinity, antigen concentration, the sensitivity of the method of detection, temperature, the length of the incubations, and other factors. The suitability of this antibody for applications other than those listed below has not been determined. The following concentration ranges are recommended starting points for this product.
Application Recommended Usage
Western Blot 1:1000-1:2000
Immunocytochemistry/Immunofluorescence (ICC/IF) 1:50-1:200

Properties
Form Liquid
Storage Buffer Supplied in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.
Storage Instructions Store at -20°C. This product is stable for 1 year upon receipt, when handled and stored as instructed.
Purification Affinity-chromatography
Isotype Rabbit IgG
Clonality Monoclonal

Examples
  • Caspase 8 Antibody, MAb, Rabbit
    • Caspase 8 Antibody, MAb, Rabbit

    All lanes use Caspase 8 Antibody, mAb, Rabbit at 1:1K dilution for 1 hour at room temperature.


Background
Target Background Thiol protease that plays a key role in programmed cell death by acting as a molecular switch for apoptosis, necroptosis and pyroptosis, and is required to prevent tissue damage during embryonic development and adulthood.Initiator protease that induces extrinsic apoptosis by mediating cleavage and activation of effector caspases responsible for FAS/CD95-mediated and TNFRSF1A-induced cell death.
Synonyms FADD-like ICE; FLICE; ICE8; MACH; MCH5; MORT1-associated CED-3 homolog; CAP4; Caspase-8 precursor;

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.